Atrial conduction times and left atrium mechanical functions in patients with active acromegaly.

abstract：:There are no data about the optimal supplementation therapy in HIV-infected patients with vitamin D (25OHD) deficiency. The aim of this study was to assess the effect of an oral monthly dose of 16,000 IU calcidiol. We performed a longitudinal cohort study of 365 HIV-infected patients (24 % females) was with sequential...

journal_title：Endocrine

authors： Bañón S,Rosillo M,Gómez A,Pérez-Elias MJ,Moreno S,Casado JL

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：:Graves' disease, an autoimmune disease with heterogeneous symptoms including Graves' orbitopathy, has a combined genetic/environmental background, where variations within CD28/CTLA-4/ICOS genes are considered as disease markers.Association of CD28c.17+3T>C(rs3116496), CTLA-4g.319C>T(rs5742909), CTLA-4c.49A>G(rs231775)...

journal_title：Endocrine

authors： Pawlak-Adamska E,Frydecka I,Bolanowski M,Tomkiewicz A,Jonkisz A,Karabon L,Partyka A,Nowak O,Szalinski M,Daroszewski J

更新日期：2017-01-01 00:00:00

abstract：:We investigated the expression and activity of cytosolic phospholipase A2 (cPLA2) in the corpus luteum during spontaneous and induced luteolysis in pseudopregnant rats. In both models, luteal PLA2 activity rose in association with functional regression and persisted during the following structural regression. Tissue c...

journal_title：Endocrine

authors： Kurusu S,Sakaguchi S,Kawaminami M,Hashimoto I

更新日期：2001-04-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures. A growing body of literature has provided indirect and some direct evidence for possible extraskeletal vitamin D-related effects. PURPOSE AND METHODS:Members of...

journal_title：Endocrine

authors： Cianferotti L,Bertoldo F,Bischoff-Ferrari HA,Bruyere O,Cooper C,Cutolo M,Kanis JA,Kaufman JM,Reginster JY,Rizzoli R,Brandi ML

更新日期：2017-05-01 00:00:00

abstract：:Cytoplasmic calcium ([Ca(2+)](i)) changes evoked by adenosine 5(1)-triphosphate (ATP) were recorded in cultured individual Leydig cells within 10-18 h after cell dispersion. [Ca(2+)](i) was monitored using Fura-2AM loaded cells with a digital ratio imaging system. Five micromolars ATP induced biphasic [Ca(2+)](i) resp...

journal_title：Endocrine

authors： Pérez-Armendariz EM,Nadal A,Fuentes E,Spray DC

更新日期：1996-06-01 00:00:00

abstract：:Aging can be defined as a progressive decline in the ability of the organism to resist stress, damage, and disease. Although there are currently over 300 theories to explain the aging phenomenon, it is still not well understood why organisms age and why the aging process can vary so much in speed and quality from indi...

journal_title：Endocrine

authors： Frisard M,Ravussin E

更新日期：2006-02-01 00:00:00

abstract：:Aging could be due to the accumulation of oxidative damage. On the other hand, growth hormone (GH) and estrogen deficiency induce deleterious effects on different tissues, and hormonal replacement could counteract these effects. We have investigated whether GH and estrogen administration modify some parameters related...

journal_title：Endocrine

authors： Castillo C,Salazar V,Ariznavarreta C,Vara E,Tresguerres JA

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:Acromegaly is a systemic metabolic disease. Growth hormone (GH) have a significant impact on adipose tissue (AT). A huge reduction of serum GH after surgical treatment may cause substantial AT redistribution. The objective of this study was to illustrate the dynamic changes in distribution of facial and abdomin...

journal_title：Endocrine

authors： Xie T,Ding H,Xia M,Zhang X,Sun W,Liu T,Gu Y,Sun C,Hu F

更新日期：2018-12-01 00:00:00

abstract：:MicroRNAs (miRNAs) have been identified to play important functions during osteoblast proliferation, differentiation, and apoptosis. The miR-17~92 cluster is highly conserved in all vertebrates. Loss-of-function of the miR-17-92 cluster results in smaller embryos and immediate postnatal death of all animals. Germline ...

journal_title：Endocrine

authors： Zhou M,Ma J,Chen S,Chen X,Yu X

更新日期：2014-03-01 00:00:00

abstract：:We hypothesized that in nonectopic Cushing syndrome there is an insufficient activity of type II (renal) 11beta-hydroxysteroid dehydrogenase (11beta-HSD2) that is related to cortisol excess, rather than to corticotropin (adrenocorticotropic hormone [ACTH]) levels. We measured plasma ACTH and urinary-free cortisol (UFF...

journal_title：Endocrine

authors： Stiefel P,García-Morillo JS,Jimenez L,Pamies E,Miranda ML,Carneado J,Villar J,Leal-Cerro A

更新日期：2002-08-01 00:00:00

abstract：:Succinic acid esters are currently under investigation as possible insulinotropic tools in the treatment of noninsulin-dependent diabetes mellitus. The present article introduces three novel nutrient esters and aims mainly to explore, in both normal and GK rats, the secretory response to such esters when tested alone ...

journal_title：Endocrine

authors： Sener A,Kadiata MM,Ladrière L,Malaisse WJ

更新日期：1997-10-01 00:00:00

abstract：:Thyroid hormones are now recognized to change in different disease states with important consequences on severity and prognosis of disease. However, little is known about thyroid hormones' alterations in acute liver failure (ALF). To study the changes in thyroid hormones and cardiac thyroid receptors during ALF, we su...

journal_title：Endocrine

authors： Kostopanagiotou G,Kalimeris K,Mourouzis I,Kostopanagiotou K,Arkadopoulos N,Panagopoulos D,Papoutsidakis N,Chranioti A,Pafiti A,Spanou D,Smyrniotis V,Pantos C

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:Parathyroid cancer is a rare tumor associated with poor prognosis particularly when disseminated. While chemotherapy and/or radiotherapy are of no clinical value in disseminated disease, immunotherapy should be considered. SUBJECT AND RESULTS:A patient with CDC73-associated metastatic parathyroid carcinoma was...

journal_title：Endocrine

authors： Sarquis M,Marx SJ,Beckers A,Bradwell AR,Simonds WF,Bicalho MAC,Daly AF,Betea D,Friedman E,De Marco L

更新日期：2020-01-01 00:00:00

abstract：:The association between cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) exon-1 +49 A/G polymorphism and Hashimoto's thyroiditis (HT) has been widely studied. The results, however, are mixed. This study provides a comprehensive evaluation of the relationship between the genetic risks of CTLA-4 +49 A/G polymorphism...

journal_title：Endocrine

authors： Qiu H,Tang W,Yin P,Cheng F,Wang L

更新日期：2014-03-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and heterogenous malignancies. Recent advances in histopathological classification according to the anatomical site of origin, proliferation rate, and extend of the disease have created a valid and powerful tool for the prognostic stratificati...

journal_title：Endocrine

authors： Alexandraki KI,Kaltsas G

更新日期：2012-02-01 00:00:00

abstract：:Autoimmune thyroid diseases (AITDs) (Hashimoto thyroiditis and Graves' disease) are complex polygenic disorders with multiple genes thought to contribute to the risk of disease. The contribution of these genes differs by different populations. The PTPN22 gene is reported to be associated with multiple autoimmune disea...

journal_title：Endocrine

authors： Alkhateeb A,Marzouka NA,Tashtoush R

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Patients with cortisol secreting adrenal adenomas present with Cushing's syndrome (CS), while 5-15% of subjects with adrenal incidentalomas have subclinical hypercortisolism (SH) as they have biochemical abnormalities suggesting autonomous cortisol secretion without associated clinical features of CS. GOALS...

journal_title：Endocrine

authors： Khawandanah D,ElAsmar N,Arafah BM

更新日期：2019-01-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) effects on the lactotroph function have been widely studied, but they probably result from paracrine interactions. No visual data about GnRH receptor in the pituitary are available. In order to identify the GnRH target cells in the pituitary of adult rats, the cellular distributio...

journal_title：Endocrine

authors： Mertani HC,Testart C,Ouhtit A,Brisson C,Morel G

更新日期：1996-04-01 00:00:00

abstract：PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

journal_title：Endocrine

authors： Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-09-01 00:00:00

abstract：:Hypothyroidism is one of the most common endocrine disorders, affecting as much as 10% of the global population. There is a rich cultural milieu of treatment history and interventions dating as far back as 2 millennia. Chinese cretins were treated with sheep thyroid in the 6th century. In 1890, transplanted animal thy...

journal_title：Endocrine

authors： Mateo RCI,Hennessey JV

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Dopamine agonist (DA)-resistant prolactinomas are rare but they constitute a real challenge, since there are few therapeutic alternatives left for these patients. DESIGN AND SETTING:Proof-of-concept study at a tertiary care, referral center. PATIENTS AND METHODS:The studied population consis...

journal_title：Endocrine

authors： Sosa-Eroza E,Espinosa E,Ramírez-Rentería C,Mendoza V,Arreola R,Mercado M

更新日期：2018-08-01 00:00:00

abstract：:The aim is to study the association of estrogen receptor α (ERα) and estrogen receptor β (ERβ) gene polymorphisms and diplotypes with ovarian response to follicle-stimulating hormone (FSH) stimulation and the hormone levels [FSH, luteinizing hormone (LH), E2] at the third day of the menstrual cycle. Three hundred wome...

journal_title：Endocrine

authors： Lazaros L,Pamporaki C,Vlahos N,Takenaka A,Kitsou C,Kosmas I,Sofikitis N,Stefos T,Zikopoulos K,Hatzi E,Georgiou I

更新日期：2014-12-01 00:00:00

abstract：:Vertebral fractures are an emerging complication of acromegaly but their prediction is still difficult occurring even in patients with normal bone mineral density. In this study we evaluated the ability of high-resolution cone-beam computed tomography to provide information on skeletal abnormalities associated with ve...

journal_title：Endocrine

authors： Maffezzoni F,Maddalo M,Frara S,Mezzone M,Zorza I,Baruffaldi F,Doglietto F,Mazziotti G,Maroldi R,Giustina A

更新日期：2016-11-01 00:00:00

abstract：:Aberrant accumulation of β-catenin plays an important role in a variety of human neoplasms. This can be caused by stabilizing mutation of β-catenin (CTNNB1, exon 3) or by mutation or deregulated expression of other components of the WNT/β-catenin signaling pathway. Accumulation of non-phosphorylated active β-catenin h...

journal_title：Endocrine

authors： Starker LF,Fonseca AL,Akerström G,Björklund P,Westin G,Carling T

更新日期：2012-12-01 00:00:00

abstract：:Nordic walking (NW), characterized by the use of two walking poles, has positive effects on several muscle groups. Muscle strength and mass decrease with age, and recently, this decrease is defined as sarcopenia. Sarcopenia may be triggered by oxidative stress. We investigated whether changes in the oxidative stress m...

journal_title：Endocrine

authors： Kawamoto R,Kohara K,Katoh T,Kusunoki T,Ohtsuka N,Abe M,Kumagi T,Miki T

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:This study aimed to analyze the clinical and genetic characteristics of Chinese children with congenital hyperinsulinemia (CHI) that is spontaneously relieved. METHODS:The patient group comprised 200 children with CHI that were treated at the Beijing Children's Hospital from January 2006 to December 2018. Th...

journal_title：Endocrine

authors： Xu ZD,Hui PP,Zhang W,Zeng Q,Zhang L,Liu M,Yan J,Wu YJ,Sang YM

更新日期：2021-01-27 00:00:00

abstract：:The original version of this article unfortunately contained a mistake in given and family names of all the authors. ...

journal_title：Endocrine

authors： Di Mario C,Petricca L,Gigante MR,Barini A,Barini A,Varriano V,Paglionico A,Cattani P,Ferraccioli G,Tolusso B,Gremese E

更新日期：2019-02-01 00:00:00

abstract：:Extrinsic and intrinsic signaling gradients determine expression patterns of pituitary-specific factors in the developing anterior pituitary gland. The temporal and spatial relations of these developmental factors are required for the determination of each of the pituitary cell lineages. Rpx is required for early diff...

journal_title：Endocrine

authors： Cohen LE

更新日期：2000-04-01 00:00:00