Role of ketoconazole treatment in urinary-free cortisol-to-cortisone and tetrahydrocortisol-to-tetrahydrocortisone ratios in nonectopic Cushing's syndrome.

abstract：:Urocortin 3 (Ucn3) is recognized as a member of the corticotropin-releasing factor (CRF) family, which plays an important role in regulating food intake. We investigated the effects of centrally administered Ucn3 on food intake and gastric emptying in mice. Intracerebroventricular (ICV)administration of Ucn3 (0.1–1 nm...

journal_title：Endocrine

authors： Ushikai M,Asakawa A,Sakoguchi T,Tanaka C,Inui A

更新日期：2011-04-01 00:00:00

abstract：:PET/CT with (18)F-fluorodeoxyglucose (FDG) or using different radiocompounds has proven accuracy for detection of adrenal metastases in patients undergoing cancer staging. It can assist the diagnostic work-up in oncology patients by identifying distant metastases to the adrenal(s) and defining oligometastatic disease ...

journal_title：Endocrine

authors： Kandathil A,Wong KK,Wale DJ,Zatelli MC,Maffione AM,Gross MD,Rubello D

更新日期：2015-05-01 00:00:00

abstract：:Insulin resistance in skeletal muscle is a key feature in the pathogenesis of type 2 diabetes (T2D) that often manifests early in its development. Pharmaceutical and dietary strategies have targeted insulin resistance to control T2D, and many natural products with excellent pharmacological properties are good candidat...

journal_title：Endocrine

authors： Shi L,Zhang T,Zhou Y,Zeng X,Ran L,Zhang Q,Zhu J,Mi M

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:The institutional database of the Thyroid Surgery Division in China-Japan Union Hospital of Jilin University was queried to audit time trend patterns in thyroid cancer (TC) management between 2008 and 2017. METHODS:Retrospective longitudinal analysis. Clinicopathological features and treatment strategies were ...

journal_title：Endocrine

authors： Sui C,Liang N,Du R,He Q,Zhang D,Li F,Fu Y,Dionigi G,Sun H

更新日期：2020-06-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) and somatostatin are the most important hypothalamic neurohormones controlling growth hormone (GH) secretion. Several neurotransmitters and neuropeptides also play an important role in the control of GH secretion, mainly acting via modulation of GHRH and somatostatin. In the pas...

journal_title：Endocrine

authors： Arvat E,Gianotti L,Giordano R,Broglio F,Maccario M,Lanfranco F,Muccioli G,Papotti M,Graziani A,Ghigo E,Deghenghi R

更新日期：2001-02-01 00:00:00

abstract：:In arthropods, development is controlled by cholesterol-derived steroid hormones: the ecdysteroids. In vertebrates and insects, steroidogenesis is positively regulated and this is mediated by cAMP. In crustaceans, ecdysteroid biosynthesis by steroidogenic organs (Y-organs) is negatively regulated by a neuropeptide, th...

journal_title：Endocrine

authors： Lachaise F,Sommé G,Carpentier G,Granjeon E,Webster S,Baghdassarian D

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:In order to study the association of G241R polymorphism of ICAM-1 gene with an earlier onset of Graves' disease (GD) and the susceptibility of K469E polymorphism to Graves' ophthalmopathy (GO) in Chinese population. STUDY DESIGN:A case-control and replication study was performed in 212 GD patients and 204 he...

journal_title：Endocrine

authors： Wang S,Sun H,Chen HY,Zhao ZF,Yang Y,Zhao YJ,Cui B,Ning G

更新日期：2007-04-01 00:00:00

abstract：:The comparative efficacy and safety profiles of selected daily 1000 IU, weekly 7000 IU and monthly 30,000 IU vitamin D 3-not previously investigated-will be evaluated. Here, a prospective, randomized clinical trial, comparing efficacy and safety of a daily single dose of 1000 IU (group A) to a once-weekly 7000 IU dose...

journal_title：Endocrine

authors： Takács I,Tóth BE,Szekeres L,Szabó B,Bakos B,Lakatos P

更新日期：2017-01-01 00:00:00

abstract：:The application of a hemolytic plaque assay to antigen-secreting endocrine cells has brought about great advances in the study of regulation of hormone secretion. The reverse hemolytic plaque assay (RHPA) has enabled quantitation of secretion at the single cell level with simultaneous analysis of the population respon...

journal_title：Endocrine

authors： Gregerson KA

更新日期：1995-05-01 00:00:00

abstract：:Recently, the microhistologic evaluation by core needle biopsy (CNB) has been reported as high accurate to diagnose thyroid nodules with previous indeterminate or not adequate fine-needle aspiration cytology. In addition, sparse data have been reported regarding the use of CNB in other conditions. Aim of this review w...

journal_title：Endocrine

authors： Trimboli P,Crescenzi A

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:Insulin resistance is an important factor in the pathogenesis of polycystic ovary syndrome (PCOS), which is associated with higher risk of metabolic syndrome (MetS) and cardiovascular complications. Early atherosclerotic lesions may be diagnosed by ultrasonographic parameters: brachial artery flow-mediated dila...

journal_title：Endocrine

authors： Krentowska A,Łebkowska A,Jacewicz-Święcka M,Hryniewicka J,Leśniewska M,Adamska A,Kowalska I

更新日期：2021-01-13 00:00:00

abstract：PURPOSE:Corticosterone prevents cold-induced stimulation of thyrotropin-releasing hormone (Trh) expression in rats, and the stimulatory effect of dibutyryl cyclic-adenosine monophosphate (dB-cAMP) on Trh transcription in hypothalamic cultures. We searched for the mechanism of this interference. METHODS:Immunohistochem...

journal_title：Endocrine

authors： Sotelo-Rivera I,Cote-Vélez A,Uribe RM,Charli JL,Joseph-Bravo P

更新日期：2017-03-01 00:00:00

abstract：:Giant prolactinomas are rare tumors characterized by their large size, compressive symptoms, and extremely high prolactin secretion. The aim of this study is to describe our experience with a series of 16 giant prolactinomas cases in terms of clinical presentation, therapeutic decisions, and final outcomes. Retrospect...

journal_title：Endocrine

authors： Andujar-Plata P,Villar-Taibo R,Ballesteros-Pomar MD,Vidal-Casariego A,Pérez-Corral B,Cabezas-Agrícola JM,Álvarez-Vázquez P,Serramito R,Bernabeu I

更新日期：2017-01-01 00:00:00

abstract：:The U.S. Institute of Medicine considers that a serum 25-hydroxyvitamin D (25OHD) concentration >20 ng/mL corresponds to optimal vitamin D status in the general population. Old studies of vitamin D status in the French general population have demonstrated high prevalence of insufficiency. We measured serum 25OHD, 1,25...

journal_title：Endocrine

authors： Souberbielle JC,Massart C,Brailly-Tabard S,Cavalier E,Chanson P

更新日期：2016-08-01 00:00:00

abstract：:Chronic ethanol exposure causes alterations in biologic membranes of different cell types. (Na + K) adenosine triphosphatase (ATPase), a membrane-bound enzyme inhibited by the acute presence of ethanol, increases its activity in rat kidney after chronic ethanol consumption. The aim of this investigation was to evaluat...

journal_title：Endocrine

authors： Rodrigo R,Rivera G,Lucero Y,Larraguibel C

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Growth hormone deficiency (GHD) is a condition associated with increased cardiovascular risk and insulin-resistance. Oxidative stress (OS) could be a mechanism underlying both these phenomena. In order to investigate plasma antioxidant defenses in such condition, we evaluated adults with GHD, compar...

journal_title：Endocrine

authors： Mancini A,Di Segni C,Bruno C,Olivieri G,Guidi F,Silvestrini A,Meucci E,Orlando P,Silvestri S,Tiano L,Pontecorvi A

更新日期：2018-01-01 00:00:00

abstract：:Strict glucose control is a well-proven therapeutic approach for peripheral neuropathies in patients with diabetes. Alpha lipoic acid (ALA) has also been accepted as a therapeutic agent for diabetic peripheral neuropathy (DPN) in the respect of pathogenesis. However, the potential of ALA as a treatment for DPN in comp...

journal_title：Endocrine

authors： Lee KA,Lee NY,Park TS,Jin HY

更新日期：2018-07-01 00:00:00

abstract：:Genetic mutations of steroidogenic factor 1 (also known as Ad4BP or Nr5a1) have increasingly been reported in patients with 46,XY disorders of sex development (46,XY disorders of sex development). However, because the phenotype of 46,XY disorders of sex development with a steroidogenic factor 1 mutation is wide-rangin...

journal_title：Endocrine

authors： Hatano M,Migita T,Ohishi T,Shima Y,Ogawa Y,Morohashi KI,Hasegawa Y,Shibasaki F

更新日期：2016-11-01 00:00:00

abstract：:Ames dwarf mice have primary deficiency of prolactin (PRL), growth hormone (GH), and thyroid-stimulating hormone (TSH), and live considerably longer than normal animals from the same line. In view of the documented effects of GH, PRL, and thyroid hormones on lean and fat body mass and skeletal growth, and the suspecte...

journal_title：Endocrine

authors： Heiman ML,Tinsley FC,Mattison JA,Hauck S,Bartke A

更新日期：2003-02-01 00:00:00

abstract：:The prevalence of adrenal incidentaloma has increased with the increasing use of imaging techniques. While majority are benign adenoma, a small but significant minority may be primary adrenal carcinoma or have endocrine hyper secretion. Existing guidance suggests that excess catecholamine and cortisol secretion should...

journal_title：Endocrine

authors： Bujawansa S,Bowen-Jones D

更新日期：2011-08-01 00:00:00

abstract：:To investigate the role of NAMPT/visfatin in euthyroid patients with Graves' disease without (GD) and with Graves' ophthalmopathy (GO), we analyzed NAMPT leukocyte expression and its serum concentration. This was a single-center, cross-sectional study with consecutive enrollment. In total, 149 patients diagnosed with ...

journal_title：Endocrine

authors： Sawicka-Gutaj N,Budny B,Zybek-Kocik A,Sowiński J,Ziemnicka K,Waligórska-Stachura J,Ruchała M

更新日期：2016-08-01 00:00:00

abstract：:Glucocorticoid hormones potentiate the toxic effects of neuronal stressors. Alteration of gene expression by glucocorticoids could contribute to neuronal susceptibility by downregulating the synthesis of proteins necessary to adapt to challenge. Using heat shock of hippocampal slices as a model for cellular insult, pr...

journal_title：Endocrine

authors： Barr CS,Dokas LA

更新日期：1998-04-01 00:00:00

abstract：:Ovulation and conversion of the follicle into the corpus luteum involve remarkable changes in vascular permeability and neovascularization of the luteinizing granulosa layer. To evaluate the importance of these vascular events in follicle rupture and luteal development, sequential experiments were designed in which ve...

journal_title：Endocrine

authors： Hazzard TM,Rohan RM,Molskness TA,Fanton JW,D'Amato RJ,Stouffer RL

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:Metastatic disease is common in medullary thyroid carcinoma (MTC) and it is usually detected by raising calcitonin and carcinoembryonic antigen (CEA) levels. Nuclear medicine imaging has an important role in lesion identification/characterisation. We aim to compare 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT perfo...

journal_title：Endocrine

authors： Souteiro P,Gouveia P,Ferreira G,Belo S,Costa C,Carvalho D,Duarte H,Sampaio IL

更新日期：2019-05-01 00:00:00

abstract：:Progesterone is a steroid which regulates neural function, thereby modulating neurotransmission, cell survival, and behavior. Previous studies by our group have shown that chronic administration of low doses of progesterone in diestrus II female rats has an antidepressant-like effect in the forced swimming test (FST)....

journal_title：Endocrine

authors： Arbo BD,Andrade S,Osterkamp G,Gomez R,Ribeiro MF

更新日期：2014-08-01 00:00:00

abstract：:To explore the regulation of follistatin gene expression, porcine granulosa cells were incubated with the translational inhibitor, cycloheximide (CHX), for periods from 6-24 h. This resulted in a 3 to 10-fold increase in follistatin mRNA accumulation compared to vehicle treated control cultures. At 20 h, CHX augmented...

journal_title：Endocrine

authors： Lindsell CE,Misra V,Murphy BD

更新日期：1995-08-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：CONTEXT:Pseudoacromegaly describes conditions with an acromegaly related physical appearance without abnormalities in the growth hormone (GH) axis. Acromegaloid facies, together with hypertrichosis, are typical manifestations of Cantú syndrome. CASE DESCRIPTION:We present a three-generation family with 5 affected memb...

journal_title：Endocrine

authors： Marques P,Spencer R,Morrison PJ,Carr IM,Dang MN,Bonthron DT,Hunter S,Korbonits M

更新日期：2018-03-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:Levothyroxine supplementation is insufficient for the management of one tenth of patients with hypothyroidism. Iodothyronine deiodinases have been suggested to play a role in residual hypothyroid symptoms of these patients by controlling local thyroid hormone homeostasis. Previous research has suggested a relat...

journal_title：Endocrine

authors： Young Cho Y,Jeong Kim H,Won Jang H,Hyuk Kim T,Ki CS,Wook Kim S,Hoon Chung J

更新日期：2017-07-01 00:00:00