Abstract:
OBJECTIVES:To describe the role of neurosurgical techniques in treatment of symptoms of multiple sclerosis (MS). METHODS:A review of the existing world literature searching (using PubMed, August 22, 2005) for key words 'multiple sclerosis' and multiple symptoms associated with MS including trigeminal neuralgia, pain (pump and rhizotomy), spasticity, intrathecal pump, hydrocephalus and stimulation (brain and spinal). RESULTS:In total, 1,404 articles met selection criteria. These were narrowed based upon uniqueness of technique described, nature of information provided and avoidance of redundancy. Further, the methods listed were classified into groups of cranial and spinal techniques. Indications, brief description of technique and outcome/side effects were noted for each technique. DISCUSSION:A vast, growing body of literature exists for various neurosurgical applications for MS treatment. Older techniques such as rhizolysis for neuralgia and rhizotomy for spasticity have been modified using stereotactic radiosurgery and deep brain stimulation, along with central nervous system stimulation and intrathecal pumps. Other applications continue to be found with varying degrees of success. CONCLUSIONS:Neurosurgical techniques, based upon proper selection criteria, can significantly improve MS-related symptoms with low procedure-associated risk and therefore can substantially improve patients' quality of life.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Patwardhan RV,Minagar A,Kelley RE,Nanda Adoi
10.1179/016164106X98224subject
Has Abstractpub_date
2006-04-01 00:00:00pages
320-5issue
3eissn
0161-6412issn
1743-1328journal_volume
28pub_type
杂志文章,评审abstract::Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1994.11740217
更新日期:1994-06-01 00:00:00
abstract::Nerve growth factor (NGF) synthesis in cultured mouse L-M fibroblast and astroglial cells can be increased after the treatment with L-threo-3,4-dihydroxyphenylserine (DOPS). Since the increase of NGF is not blocked by the treatment with decarboxylase inhibitor, DOPS may have direct effect to increase the NGF content. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1994.11740227
更新日期:1994-06-01 00:00:00
abstract::We describe a case of rebleeding from an intracranial vertebral dissecting aneurysm following proximal clipping. This case suggests that proximal clipping alone may not be an adequate surgical procedure to prevent rebleeding. Surgical treatment of intracranial dissecting aneurysms in the vertebral artery presenting as...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1080/01616412.1994.11740213
更新日期:1994-04-01 00:00:00
abstract::The abnormal muscle response, elicited by electrical stimulation of one branch of the facial nerve and recorded from muscles innervated by another branch, has been used previously as an objective sign of hemifacial spasm in the development of animal models of this disorder. In the present study we recorded spontaneous...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1994.11740241
更新日期:1994-08-01 00:00:00
abstract::Complete thrombosis followed by recanalization of giant aneurysms is an infrequent process that has been exceptionally mentioned in relation to nongiant saccular aneurysms. A 25-year-old male presented with a right temporal hematoma and associated subarachnoid hemorrhage. Cerebral angiography revealed a small blister-...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164103771953961
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:In about 10% of glioblastoma patients, preoperative MRI discloses the presence of tumor cysts. Whereas the impact of cystic appearance on prognosis has been discussed extensively, only little is known about the tumor cyst fluid. In this study, we tested the feasibility of the surface enhanced laser desorptio...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164113X13756993777580
更新日期:2013-12-01 00:00:00
abstract::The mechanism of cerebral ischaemic injury is complex and likely involves more than a single pathophysiologic event. Drugs are available which interfere with numerous harmful biochemical and pharmacologic processes begun by ischaemia. Hence, combination chemotherapy might be useful in cerebral ischaemia. The purpose o...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1995.11740301
更新日期:1995-04-01 00:00:00
abstract::This paper describes a previously unreported clinical onset of carcinomatous meningitis with bilateral deafness. Typical changes in the cerebrospinal fluid aside from positive cytology findings are reviewed. In cases of suspected carcinomatous meningitis the clustering of increased CSF protein, lactate, decreased gluc...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164102101200708
更新日期:2002-10-01 00:00:00
abstract::Insertion of pedicle screws in the thoracolumbar spine can be challenging. Incorrect placement can lead to a failure of fusion or to significant neurologic morbidity. Recently, techniques utilizing intraoperative monitoring and stereotaxis have been developed to achieve proper screw placement. While these techniques m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740877
更新日期:1997-12-01 00:00:00
abstract::The possible role of nitric oxide (NO) on vibrissa-stimulated increase of regional cerebral cerebral blood flow (rCBF) and cerebral metabolic rate of glucose (rCMRglu) was investigated in conscious Wistar rats by using an inhibitor of NO synthase, NG-nitro-L-arginine (NOLAG) at a concentration of 30 mg/kg. In vivo aut...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740103
更新日期:1993-02-01 00:00:00
abstract::The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199388
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hypothermia has shown promise as a neuroprotective strategy for stroke. The use of whole body hypothermia has limited clinical utility due to many severe side effects. Selective brain cooling, or local brain hypothermia, has been previously proposed as an alternative treatment strategy. This st...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1187827
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X204666
更新日期:2007-06-01 00:00:00
abstract::The influence of acidic fibroblast growth factor (aFGF) on sleep was studied in conscious rabbits. An intravenous (i.v.) bolus injection of aFGF induced a significant increase in sleep duration in comparison with animals that received vehicle solution. Somnogenic effects were obtained 30 min following i.v. aFGF admini...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1996.11740472
更新日期:1996-12-01 00:00:00
abstract::The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1998.11740573
更新日期:1998-10-01 00:00:00
abstract::An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1980.11739588
更新日期:1980-01-01 00:00:00
abstract::Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1428276
更新日期:2018-03-01 00:00:00
abstract::The survival of a group of patients with malignant gliomas of the brain submitted to radical surgery and radiotherapy was studied. The average survival was nearly 4 times longer with X-ray treatment than with cobalt 60 irradiation when a comparison was made between 24 patients with glioblasto-astroblastoma (grade 3-4)...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1987.11739796
更新日期:1987-09-01 00:00:00
abstract:OBJECTIVE:Infection is a major complication and risk factor of cerebrospinal fluid (CSF) shunting procedures. Recently, antibiotic-impregnated shunt systems have been developed in an attempt to prevent or reduce the CSF infection. The aim of this study was to determine the efficacy of silver-impregnated polyurethane ve...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/174313209X380973
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Intracranial artery stenosis may be the most frequent cause of ischemic stroke in the world. Early detection of asymptomatic intracranial artery stenosis may allow for therapeutic intervention. Most elements of the Framingham stroke risk profile (FSRP) are also risk factors for intracranial artery stenosis....
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000024
更新日期:2012-05-01 00:00:00
abstract::We developed a confocal laser scanning microscope for intra-operative imaging of brain tumors using near infrared fluorescence. The quality of near infrared images of Indocyanine Green (ICG) was compared with the surgical confocal scanning (SCS) microscope and a conventional charge-coupled device (CCD) camera; we comp...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11740714
更新日期:2000-07-01 00:00:00
abstract::The objective of this study was to improve the ability to detect cerebrovascular complications in patients undergoing complicated neurosurgical procedures using on-line monitoring of cerebral pH with in vivo microdialysis. We employed on-line pH monitoring in patients with a variety of neurosurgical procedures includi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740497
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To investigate risk factors for neurological complications after off-pump coronary artery bypass grafting (OPCABG). METHODS:We reviewed the cases of 813 patients who underwent OPCABG between August 2010 and September 2013.Data from preoperative 320 dynamic volume computed tomography (CT), CT angiography (CTA...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000030
更新日期:2015-05-01 00:00:00
abstract::The authors have done a revision of 450 patients admitted during the last 3 years to the emergency service of the Hospital de S. José with the diagnosis of CVA. In this retrospective study were included the patients of greater than or equal to 3 degree of the RLS/85 coma scale, the diagnostic being confirmed by CAT, a...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1992.11740023
更新日期:1992-01-01 00:00:00
abstract::This study was designed to evaluate the effects of two consecutive ischaemias on extracellular monoaminergic neurotransmitter concentrations. The data on the neuroamine changes induced by the second ischaemia could be used to assess the delay in aminergic neurotransmission subsequent to the primary injury. Dopamine (D...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740134
更新日期:1993-06-01 00:00:00
abstract::Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164102101199503
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000216
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:Susceptibility-weighted (SW) magnetic resonance (MR) imaging is a sensitive test to detect intravenous deoxygenated blood. On SW images, dilated appearing draining veins in tissue with perfusion impairment occur due to an increase in intravenous deoxyhemoglobin levels, and could indicate poor perfusion areas...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12644252260510
更新日期:2011-04-01 00:00:00
abstract::The normal cerebral circulation has the ability to maintain a stable cerebral blood flow over a wide range of cerebral perfusion pressures and this is known as cerebral autoregulation. This autoregulation may be impaired in the injured brain. Closed head injury was induced in 28 Sprague-Dawley rats weighing 400-450 g....
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740832
更新日期:1997-08-01 00:00:00
abstract::The decrease in intracellular creatine concentration in Duchenne muscular dystrophy may contribute to the deterioration of intracellular energy homeostasis and may thus be one of the factors aggravating muscle weakness and degeneration. Oral creatine supplementation should have potential in alleviating the clinical sy...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11741051
更新日期:2000-03-01 00:00:00