Abstract：
:The alar plate of the prosencephalon differentiates into a tectum-like structure when transplanted into the mesencephalon around the 10-somite stage. Here, we report on the projection pattern of the retinal ganglion cells to the transplants. Optic nerve fibers were labeled with horseradish peroxidase (HRP) and 3H-proline, and the innervation of the optic nerve fibers to the chimeric tectum was analyzed by HRP histochemistry on whole-mounted specimens, by autoradiography and by electron microscopy on embryonic day 16. In the chimeric tectum, the transplant was distinguished from the host by difference in nuclear structure between the quail and the chick cells. It was shown that the transplant had the laminar pattern of the optic tectum when the transplant was integrated into the host mesencephalon. The whole-mount HRP histochemistry showed that the optic nerve fibers extend to the transplants. Autoradiography showed that the distribution pattern of silver grains was similar in both the host and the transplant. These results may indicate that the optic nerve fibers turn to the transplant and terminate on the transplant. Electron microscopy further confirmed that optic nerve fibers ended by making synaptic contacts with the dendrites in the transplant region of the tectum. These results indicate that the transplant with the laminar pattern of the optic tectum is a true tectum receiving input from the eye.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Nakamura H,Matsui KA,Takagi S,Fujisawa Hdoi
10.1016/0168-0102(91)90042-wsubject
Has Abstractpub_date
1991-08-01 00:00:00pages
189-97issue
3eissn
0168-0102issn
1872-8111pii
0168-0102(91)90042-Wjournal_volume
11pub_type
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doi：10.1016/0168-0102(94)00864-c
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pub_type： 杂志文章,评审
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更新日期：2017-03-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-07-01 00:00:00
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更新日期：2002-10-01 00:00:00
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journal_title：Neuroscience research
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doi：10.1016/j.neures.2007.12.002
更新日期：2008-03-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(91)90101-4
更新日期：1991-10-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2015.07.002
更新日期：2015-12-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(98)00075-3
更新日期：1998-10-01 00:00:00
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更新日期：2020-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1985-04-01 00:00:00
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更新日期：2020-04-01 00:00:00
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journal_title：Neuroscience research
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更新日期：2013-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：1992-12-01 00:00:00
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更新日期：2009-07-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
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更新日期：2009-10-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.11.009
更新日期：2006-03-01 00:00:00
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更新日期：1993-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：1988-12-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
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更新日期：2010-07-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2018.07.007
更新日期：2019-07-01 00:00:00
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journal_title：Neuroscience research
pub_type： 历史文章,杂志文章,评审
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更新日期：2007-01-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/s0168-0102(01)00209-7
更新日期：2001-05-01 00:00:00
abstract：:Glutamate receptor subtypes mediating excitatory synaptic neurotransmission in the cerebellar cortex are briefly reviewed from molecular biological, electrophysiological and pharmacological points of view. In particular, molecular biological findings of a novel family of AMPA-selective glutamate receptors are introduc...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/0168-0102(91)90023-r
更新日期：1991-01-01 00:00:00
