Probing the function of neuronal populations: combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging.

abstract：:Recent studies have compared default-mode network (DMN) connectivity in different arousal levels to investigate the relationship between consciousness and DMN. The comparison between the DMN in rapid eye movement (REM) sleep with that in non-REM (NREM) sleep is useful for revealing the relationship between arousal lev...

journal_title：Neuroscience research

authors： Koike T,Kan S,Misaki M,Miyauchi S

更新日期：2011-04-01 00:00:00

abstract：:To study the contribution of retinal and cortical afferents to the patterns of glutamate- and homocysteate-like immunoreactivities in dorsal lateral geniculate, combined retinal and cortical ablations were performed in rats. In controls, glutamate immunoreactivity was in terminal-like dots and neurons. Homocysteate im...

journal_title：Neuroscience research

authors： Grandes P,Mateos JM,Azkue J,Sarría R,Cuénod M,Streit P

更新日期：1997-04-01 00:00:00

abstract：:A disynaptic projection from the spinal cord to the striatum was observed in the rat light and electron microscopically. An anterograde tracer, wheat germ agglutinin conjugated to horseradish peroxidase was injected into the ventral gray matter of the upper cervical spinal cord, and a retrograde tracer, biotinylated d...

journal_title：Neuroscience research

authors： Nakamura Y,Otake K,Tokuno H

更新日期：2006-09-01 00:00:00

abstract：:We investigated the neural mechanisms underlying the ability to cope in atypical or novel situations using tools. We hypothesized that two cognitive components support this ability: adaptive coordination (for adapting to situational demands) and cognitive inhibition (for inhibiting the incongruent actions afforded by ...

journal_title：Neuroscience research

authors： Wakusawa K,Sugiura M,Sassa Y,Jeong H,Yomogida Y,Horie K,Sato S,Yokoyama H,Kure S,Takei N,Mori N,Kawashima R

更新日期：2015-01-01 00:00:00

abstract：:To investigate the effect of abrupt or non-abrupt isolation stress on the classical conditioned histamine release, socially isolated or paired guinea pigs underwent conditioning procedures in which ovalbumin (OA) as an unconditioned stimulus (US) and dimethylsulfide (sulfur smelling) as a conditioned stimulus (CS) wer...

journal_title：Neuroscience research

authors： Irie M,Nagata S,Endo Y

更新日期：2002-09-01 00:00:00

abstract：:Prepulse inhibition (PPI) and habituation of the acoustic startle reflex (ASR) are considered to be candidate endophenotypes of schizophrenia. However, to our knowledge, only one group has investigated these startle measures in Asian patients with schizophrenia. In the present study, we evaluated these startle measure...

journal_title：Neuroscience research

authors： Takahashi H,Iwase M,Ishii R,Ohi K,Fukumoto M,Azechi M,Ikezawa K,Kurimoto R,Canuet L,Nakahachi T,Iike N,Tagami S,Morihara T,Okochi M,Tanaka T,Kazui H,Yoshida T,Tanimukai H,Yasuda Y,Kudo T,Hashimoto R,Takeda M

更新日期：2008-11-01 00:00:00

abstract：:Some evidence suggests that sleep deprivation might impair synaptic plasticity and produce oxidative stress in the hippocampus. However it is not clear whether impairment of long-term potentiation depends on the oxidative stress evoked by sleep deprivation protocol. In this study we aimed to investigate the effects of...

journal_title：Neuroscience research

authors： Süer C,Dolu N,Artis AS,Sahin L,Yilmaz A,Cetin A

更新日期：2011-05-01 00:00:00

abstract：:The coexistence of varying combinations of substance P (SP), somatostatin (SOM), thyrotropin-releasing hormone (TRH) and met-enkephalin-Arg-Gly-Leu (ENK) with 5-hydroxytryptamine (5-HT) as semiquantitatively revealed by immunocytochemistry in neuronal perikarya of the raphe pallidus et obscurus in the guinea-pig was a...

journal_title：Neuroscience research

authors： Chiba T,Masuko S

更新日期：1989-10-01 00:00:00

abstract：:The intent of the present study is to define the brainstem nuclei which give rise to CGRP-immunolabeled afferents to the inferior olivary complex of the mouse. A technique which combines retrograde transport of fluorescent microspheres with immunohistochemistry was used to address this question. In the present study, ...

journal_title：Neuroscience research

authors： Peltier AC,Bishop GA

更新日期：1999-08-01 00:00:00

abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...

journal_title：Neuroscience research

authors： Candelario-Jalil E,Alvarez D,Merino N,León OS

更新日期：2003-10-01 00:00:00

abstract：:In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...

journal_title：Neuroscience research

authors： Lai Z,Zhai Q,Liu Z,Roos P,Nyberg F

更新日期：1995-10-01 00:00:00

abstract：:Excitatory synaptic connections between rat hippocampal neurons were established in tissue culture. The electrophysiological and pharmacological properties of these synapses were studied with the use of the tight-seal whole-cell recording technique. The excitatory postsynaptic current (EPSC) in a dissociated CA1 neuro...

journal_title：Neuroscience research

authors： Ozawa S,Iino M,Abe M

更新日期：1991-10-01 00:00:00

abstract：:Changes in synaptic efficacy at the parallel fiber (PF)-Purkinje cell (PC) synapse are postulated to be a cellular basis for motor learning. Although long-term efficacy changes lasting more than an hour at this synapse, i.e., long-term potentiation and depression, have been extensively studied, relatively short lastin...

journal_title：Neuroscience research

authors： Goto J,Inoue T,Kuruma A,Mikoshiba K

更新日期：2006-05-01 00:00:00

abstract：:Electrical stimulation could enhance nerve regeneration and functional recovery. The objective of this study was to evaluate the regenerative effects of implanted electrodes with different contacts in resected sciatic nerve. Sciatic nerve resection and microsurgical repair models were established and randomly divided ...

journal_title：Neuroscience research

authors： Yu AP,Shen YJ,Qiu YQ,Li J,Shen YD,Wang XM,Cong M,He QR,Chen QZ,Jiang S

更新日期：2019-08-01 00:00:00

abstract：:We have generated a transgenic mouse model in which astrocytes express an enhanced green fluorescent protein (EGFP) under the control of the mouse glial fibrillary acidic protein (GFAP) promoter. EGFP, which is characteristically found throughout the cell, was expressed in these animals even in astrocytic fine process...

journal_title：Neuroscience research

authors： Suzuki R,Watanabe J,Arata S,Funahashi H,Kikuyama S,Shioda S

更新日期：2003-12-01 00:00:00

abstract：:Immuno-electron microscopy specifically enhanced with silver staining has been used to demonstrate the localization of calcitonin gene-related peptide (CGRP) in the ependymocytes of the hamster subcommissural organ (SCO). Hamster SCO consists of the ependymal and hypendymal cell layers, the latter being arranged as ro...

journal_title：Neuroscience research

authors： Tsai MH,Wu CH,Chen WP,Shieh JY,Wen CY

更新日期：2003-09-01 00:00:00

abstract：:Neurons in the inferior temporal (IT) cortex respond not only to the shape, color or texture of objects, but to the horizontal positional disparity of visual features in the right and left retinal images. IT neurons with similar shape selectivity cluster in columns. In this study, we examined how IT neurons are spatia...

journal_title：Neuroscience research

authors： Yoshiyama K,Uka T,Tanaka H,Fujita I

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Global field synchronization (GFS) has recently been introduced to measure functional synchronization in frequency-domain EEG data. This study explored GFS values and its clinical significance in patients with Alzheimer's disease (AD). METHOD:EEGs were recorded from 22 AD patients and 23 age-matched healthy...

journal_title：Neuroscience research

authors： Park YM,Che HJ,Im CH,Jung HT,Bae SM,Lee SH

更新日期：2008-10-01 00:00:00

abstract：:POZ/BTB proteins influence cellular development and in some examples act as oncoproteins. However, several POZ/BTB transcription factors have been found in terminally differentiated neurons, where their functions remain unknown. One example is NAC1, a constitutively-expressed protein that can regulate behaviors associ...

journal_title：Neuroscience research

authors： Korutla L,Neustadter JH,Fournier KM,Mackler SA

更新日期：2003-05-01 00:00:00

abstract：:Trauma to the spinal cord initiates a series of cellular and biochemical processes that damage both neurons and glia. TGF-beta and its receptors are expressed around the injury site following a spinal cord injury. Here, we report that the intrathecal administration of a neutralizing antibody to TGF-beta1 in rats with ...

journal_title：Neuroscience research

authors： Kohta M,Kohmura E,Yamashita T

更新日期：2009-12-01 00:00:00

abstract：:In the present study we measured cardiovascular and respiratory reflexes evoked by administration of bradykinin and capsaicin into the hindlimb vasculature of anaesthetised rats, whilst simultaneously recording activity of sensory afferents on the adventitial surface of femoral arteries and veins. Bradykinin (0.9 nmol...

journal_title：Neuroscience research

authors： Smith PJ,McQueen DS

更新日期：2004-11-01 00:00:00

abstract：:Excitatory inputs to layer V neurons of the parasubiculum and medial entorhinal cortex were examined in rat brain slices with intracellular and field potential recordings. Single extracellular stimuli to layer V evoked subthreshold excitatory postsynaptic potentials (EPSPs) or a long duration (>100 ms) depolarization ...

journal_title：Neuroscience research

authors： Funahashi M,Matsuo R,Stewart M

更新日期：2002-01-01 00:00:00

abstract：:In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contralateral to the...

journal_title：Neuroscience research

authors： Ishida Y,Todaka K,Kuwahara I,Nakane H,Ishizuka Y,Nishimori T,Mitsuyama Y

更新日期：1998-04-01 00:00:00

abstract：:To elucidate the interaction between nitric oxide (NO) and substance P (SP) in neurogenic inflammatory responses, we measured the change in the degree of Evans blue leakage and NO levels in perfusate from the subcutaneous space in the rat instep following noxious heat stimulation (47 degrees C for 30 min). Furthermore...

journal_title：Neuroscience research

authors： Yonehara N,Yoshimura M

更新日期：2000-01-01 00:00:00

abstract：:Eugenol modulates neuronal activity through actions on voltage-gated ionic channels and/or transient receptor potential channels. We previously suggested that eugenol inhibited cellular (and/or network) mechanisms essential for the maintenance of the respiratory burst activity in a brainstem-spinal cord preparation fr...

journal_title：Neuroscience research

authors： Kotani S,Yazawa I,Onimaru H,Izumizaki M

更新日期：2020-06-01 00:00:00

abstract：:Alzheimer's disease (AD) is a chronic and fatal disease, in which neuronal damage at its late stage cannot be easily reversed. Because AD progression is caused by multiple factors including diverse cellular processes, studies on AD pathogenesis at the molecular and cellular level are challenging. Based on the lessons ...

journal_title：Neuroscience research

authors： Chun H,Lee CJ

更新日期：2018-01-01 00:00:00

abstract：:Amphibian metamorphosis is characterized by rapid tissue remodeling and drastic changes in the body structure and function. Like other organs, olfactory system also undergoes a dramatic rearrangement as the animal experiences transition from aquatic to terrestrial habitat. Reactive oxygen species (ROS) are known to pl...

journal_title：Neuroscience research

authors： Gaupale TC,Londhe J,Ghaskadbi S,Subhedar NK,Bhargava S

更新日期：2012-02-01 00:00:00

abstract：:Nerve growth factor (NGF)-like immunoreactivity was demonstrated in the rat pituitary intermediate lobe by indirect immunofluorescence method using antisera specific to beta-NGF isolated from adult male mouse submaxillary salivary gland. Co-culture of frozen or fresh intermediate lobes with newborn rat superior cervic...

journal_title：Neuroscience research

authors： Soinila S,Lakshmanan J,Lahtinen T

更新日期：1988-12-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear protein that plays an essential role in diverse neurobiological processes. However, the role of PPARα on the sleep modulation is unknown. Here, rats treated with an intrahypothalamic injection of Wy14643 (10μg/1μL; PPARα agonist) enhanced wakefu...

journal_title：Neuroscience research

authors： Mijangos-Moreno S,Poot-Aké A,Guzmán K,Arankowsky-Sandoval G,Arias-Carrión O,Zaldívar-Rae J,Sarro-Ramírez A,Murillo-Rodríguez E

更新日期：2016-04-01 00:00:00

abstract：:The critical flicker-fusion frequency (CFF), defined as the frequency at which a flickering light is indistinguishable from a continuous light, is a useful measure of visual temporal resolution. The mouse CFF has been studied by electrophysiological approaches such as recordings of the electroretinogram (ERG) and the ...

journal_title：Neuroscience research

authors： Nomura Y,Ikuta S,Yokota S,Mita J,Oikawa M,Matsushima H,Amano A,Shimonomura K,Seya Y,Koike C

更新日期：2019-11-01 00:00:00