Abstract:
:The anti-inflammatory activity of the aqueous extract of Chromolaena odorata was investigated in rats using the carrageenan-induced oedema, cotton pellet granuloma and formalin-induced oedema methods. The extract was administered orally at doses of 25, 50, 100 and 200 mg/kg. In the carrageenan method the paw oedema was significantly reduced by all the doses of the extract administered, with the 200 mg/kg dose producing the highest oedema inhibition (80.5%). In the cotton pellet method, granuloma weight was significantly reduced from 14 +/- 0.1 to 9.0 +/- 0.1 mg, while in the formaldehyde induced arthritis the extract inhibited the oedema during the 10-day period. In conclusion, this study has established the anti-inflammatory activity of C. odorata and, thus, justifies the traditional uses of the plant in the treatment of wounds and inflammation.
journal_name
Inflammopharmacologyjournal_title
Inflammopharmacologyauthors
Owoyele VB,Adediji JO,Soladoye AOdoi
10.1163/156856005774649386subject
Has Abstractpub_date
2005-01-01 00:00:00pages
479-84issue
5-6eissn
0925-4692issn
1568-5608journal_volume
13pub_type
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journal_title:Inflammopharmacology
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journal_title:Inflammopharmacology
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journal_title:Inflammopharmacology
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journal_title:Inflammopharmacology
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abstract::Nicotine mediates some of the injurious effects caused by consuming tobacco products. The aim of this work is to investigate the protective effects of Mentha spicata extract (ME) supplementation on the testis and brain of nicotine-induced oxidative damage rats. ME extract showed interesting hydrogen peroxide-scavengin...
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journal_title:Inflammopharmacology
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journal_title:Inflammopharmacology
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更新日期:2020-12-01 00:00:00