Abstract：
:Tumour necrosis factor (TNF) family ligands and their corresponding receptors play important roles in the immune system and are involved in immune regulation such as lymphoid development, cell proliferation, differentiation, activation and death. Antibodies against these ligands and receptors together with Fc-fusion proteins, have been particularly useful as immunological tools in addressing the underlying involvement of these proteins in these contexts and furthermore, have given us hope in using them as potential therapeutic agents. Over last few years, there have been many additions to these ever-growing TNF family ligands and their receptors. Here, we have generated and characterised a set of monoclonal antibodies, together with mAbs from the HLDA workshop, against DcR1, DcR2, DR4, DR5, TRAIL, APRIL, BAFF, BAFF-R, BCMA, and TACI, which may be useful in phenotypic and functional studies of the role of TNF and TNF receptor family in immune function and regulation in relation to health and disease.
journal_name
Cell Immunoljournal_title
Cellular immunologyauthors
Ch'en PF,Xu XG,Liu XS,Liu Y,Song CJ,Screaton GR,Jin BQ,Xu XNdoi
10.1016/j.cellimm.2005.08.010subject
Has Abstractpub_date
2005-07-01 00:00:00pages
78-85issue
1-2eissn
0008-8749issn
1090-2163pii
S0008-8749(05)00157-7journal_volume
236pub_type
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journal_title：Cellular immunology
pub_type： 杂志文章
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journal_title：Cellular immunology
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2000-06-15 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Cellular immunology
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
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更新日期：1985-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-01-01 00:00:00
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journal_title：Cellular immunology
pub_type： 杂志文章
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更新日期：2001-03-15 00:00:00
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pub_type： 杂志文章
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journal_title：Cellular immunology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Cellular immunology
pub_type： 杂志文章
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journal_title：Cellular immunology
pub_type： 杂志文章
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journal_title：Cellular immunology
pub_type： 杂志文章
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journal_title：Cellular immunology
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journal_title：Cellular immunology
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更新日期：2010-01-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Cellular immunology
pub_type： 杂志文章
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更新日期：2004-04-01 00:00:00
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journal_title：Cellular immunology
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更新日期：2010-01-01 00:00:00
