Recovery from parkinson syndrome and prolonged visually evoked potentials in hepatic encephalopathy.

abstract：:α-asarone (ASR) is a major bioactive compound isolated from the rhizome of Acorus tatarinowii Schott and it has extensive biological effects. Clinically, anxiety disorder is a common comorbidity of chronic pain. However, limited information is available regarding the effects of ASR on chronic pain-related anxiety. Thi...

journal_title：Metabolic brain disease

authors： Tian J,Tian Z,Qin SL,Zhao PY,Jiang X,Tian Z

更新日期：2017-12-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder, characterized by accumulation and deposition of Aβ peptide in human brain. The present study aimed to determine the protective effect of catechin rich extract of MERM (methanolic extract of Rhizophora mucronata) on Aβ (25-35) induced cognitive impai...

journal_title：Metabolic brain disease

authors： Suganthy N,Malar DS,Devi KP

更新日期：2016-08-01 00:00:00

abstract：:We discuss the case of a rare and often unrecognized neurologic syndrome, called Acquired Hepatocerebral Degeneration (AHD), observed in patients with advanced liver disease and portosystemic shunts. The clinical manifestations can be very heterogeneous and in our case included a combination of cerebellar and extrapyr...

journal_title：Metabolic brain disease

authors： Pigoni A,Iuculano F,Saetti C,Airaghi L,Burdick L,Spreafico S,Curioni M,Lombardi R,Valenti L,Fracanzani AL,Fargion S

更新日期：2018-02-01 00:00:00

abstract：:Although the key contributors of altering neurological function in hepatic encephalopathy are relatively well known, the electrophysiological mechanism of CA1 damage, a key vulnerable area during hyperammonemia, have not yet been defined. Therefore, here we focus on the electrophysiological mechanisms of cognitive imp...

journal_title：Metabolic brain disease

authors： Tahamtan M,Aghaei I,Pooladvand V,Sheibani V,Khaksari M,Shabani M

更新日期：2017-06-01 00:00:00

abstract：:The experimental model of central pontine myelinolysis--chronic (4-day) hyponatremia induced by daily injections of hypotonic dextrose solutions and vasopressin followed by rapid correction with saline--was used in young fasted and thirsted mice. In normal controls chronic fasting and thirsting lowered plasma and brai...

journal_title：Metabolic brain disease

authors： Thurston JH,Hauhart RE,Nelson JS

更新日期：1987-12-01 00:00:00

abstract：:There is evidence to suggest that, in acute liver failure (ALF), brain ammonia and proinflammatory cytokines may act synergistically to cause brain edema and its complications (intracranial hypertension, brain herniation). However, the molecular mechanisms involved remain to be established. In order to address this is...

journal_title：Metabolic brain disease

authors： Chastre A,Jiang W,Desjardins P,Butterworth RF

更新日期：2010-03-01 00:00:00

abstract：:In the brain hyperammonemia interferes with ion homeostasis, membrane potentials, neurotransmission, and neurotransmitter recycling and reduces metabolic rates for oxygen and glucose. Because, cerebral blood flow (CBF) is closely coupled to metabolism, CBF is most often reduced in diseases associated with hyperammonem...

journal_title：Metabolic brain disease

authors： Larsen FS

更新日期：2002-12-01 00:00:00

abstract：:In the original publication of the article, author name Masoumeh Asadbegi was incorrectly written as Masoumeh Asadbeigi. The authors regret the oversight. ...

journal_title：Metabolic brain disease

authors： Sajadi A,Amiri I,Gharebaghi A,Komaki A,Asadbegi M,Shahidi S,Mehdizadeh M,Asl SS

更新日期：2017-12-01 00:00:00

abstract：:Hepatic encephalopathy (HE) is a neuropsychiatric syndrome which develops in patients with severe liver diseases and/or portal-systemic shunting. Minimal HE, the earliest manifestation of HE, has drawn increasing attention in the last decade. Minimal HE is associated with a series of brain functional changes, such as ...

journal_title：Metabolic brain disease

authors： Zhang LJ,Wu S,Ren J,Lu GM

更新日期：2014-09-01 00:00:00

abstract：:A structured analytic approach was developed to evaluate enzyme kinetic parameters using non-linear least-squares fitting. The approach was implemented in a software package called KinSim and designed to run on Windows 95, 98, and NT platforms. The software and the theoretical approach were tested using kinetic data o...

journal_title：Metabolic brain disease

authors： Mason GF,Lai JC

更新日期：2000-06-01 00:00:00

abstract：:Following axonal interruption, structural, metabolic and physiological parameters change in motorneurons. Also, glial cells are involved in this process. Microglia proliferate and express new proteins such as vimentin or MHC antigens. Astrocytes show hypertrophy, increased GFAP synthesis, and formation of lamellae. Bo...

journal_title：Metabolic brain disease

authors： Kreutzberg GW,Graeber MB,Streit WJ

更新日期：1989-03-01 00:00:00

abstract：:A study evaluating zinc supplementation in patients with Alzheimer's disease yielded variable zinc plasma levels in spite of positive cognitive and physiological results. In an attempt to raise and sustain plasma zinc levels, a single patient was given 15 mg zinc/day with various combinations of vitamins. A sustained ...

journal_title：Metabolic brain disease

authors： Potocnik FC,van Rensburg SJ,Hon D,Emsley RA,Moodie IM,Erasmus RT

更新日期：2006-09-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system which causes chronic demyelination. Hydroxychloroquine (HCQ) possess immunosuppressive and anti-inflammatory properties. The aim of this study was to investigate the effect of HCQ on miR-219 and miR-155-3p expression changes in MS-...

journal_title：Metabolic brain disease

authors： Mazloumfard F,Mirian M,Eftekhari SM,Aliomrani M

更新日期：2020-12-01 00:00:00

abstract：:Traumatic brain injury (TBI) results in severe neurological impairments without effective treatments. Inflammation appears to be an important contributor to key pathogenic events such as secondary brain injury following TBI and therefore serves as a promising target for novel therapies. We have recently demonstrated t...

journal_title：Metabolic brain disease

authors： Yang L,Liu Z,Ren H,Zhang L,Gao S,Ren L,Chai Z,Meza-Romero R,Benedek G,Vandenbark AA,Offner H,Li M

更新日期：2017-10-01 00:00:00

abstract：:To investigate the hypothesis that neurotoxic metals can exert their toxicity through the direct inhibition of monoamine oxidases (MAOs), the effects of several neurotoxic metal ions on type A (MAO-A) and type B (MAO-B) monoamine oxidase activities in rat forebrain nonsynaptic mitochondria and rat liver mitochondria w...

journal_title：Metabolic brain disease

authors： Leung TK,Lim L,Lai JC

更新日期：1992-09-01 00:00:00

abstract：:To assess whether EGb761 could protect elderly diabetic mice with cognitive disorders and explore the role of beclin-1-mediated autophagy in these protective effects. Two-month-old male db/db-/- mice and wild-type C57/BL6 mice were randomly divided into six groups: db/db-/- control, db/db-/- 50 mg, db/db-/- 100 mg, wi...

journal_title：Metabolic brain disease

authors： Guan ZF,Zhang XM,Tao YH,Zhang Y,Huang YY,Chen G,Tang WJ,Ji G,Guo QL,Liu M,Zhang Q,Wang NN,Yu ZY,Hao-Yang,Wu GF,Tang ZP,Du ZG,Shang XL,Liu YC,Mei GH,Guo JC,Zhou HG

更新日期：2018-12-01 00:00:00

abstract：:The radiological spectrum of neuromyelitis optica has become broader since the detection of aquaporin4 antibodies. We report a case of neuromyelitis optica patient with pseudotumoral encephalic lesion. A 66 year-old woman presented with sudden left lateral homonymous hemianopsia. A brain MRI showed an isolated and ext...

journal_title：Metabolic brain disease

authors： Fargeot G,Aboab J,Savatovsky J,Marignier R,Lecler A,Gout O

更新日期：2018-02-01 00:00:00

abstract：:Chronic ethanol ingestion results in an "up-regulation" of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor in mouse brain. This increase in receptors is associated with ethanol withdrawal seizures, which can be attenuated by NMDA receptor antagonists. Chronic exposure to ethanol (3 days) of rat cerebella...

journal_title：Metabolic brain disease

authors： Hoffman PL

更新日期：1995-03-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) represents a partially-understood cerebrovascular disease of high incidence, morbidity and mortality. We, herein, report the findings of our study concerning the role of two important adenosinetriphosphatases (ATPases) in a porcine model of spontaneous ICH that we have recent...

journal_title：Metabolic brain disease

authors： Bimpis A,Papalois A,Tsakiris S,Kalafatakis K,Zarros A,Gkanti V,Skandali N,Al-Humadi H,Kouzelis C,Liapi C

更新日期：2013-09-01 00:00:00

abstract：:Near infrared radiation (NIR) is known to penetrate and affect biological systems in multiple ways. Recently, a series of experimental studies suggested that low intensity NIR may protect neuronal cells against a wide range of insults that mimic diseases such as stroke, brain trauma and neurodegeneration. However, the...

journal_title：Metabolic brain disease

authors： Yu Z,Liu N,Zhao J,Li Y,McCarthy TJ,Tedford CE,Lo EH,Wang X

更新日期：2015-04-01 00:00:00

abstract：:Stress-induced activation of the expression of the endoplasmic reticulum (ER)-resident chaperon and member of the protein disulfide isomerase family erp72 was studied after transient cerebral ischemia in vivo using the four-vessel occlusion method and experimental depletion of ER calcium stores in primary neuronal cel...

journal_title：Metabolic brain disease

authors： Paschen W,Gissel C,Linden T,Doutheil J

更新日期：1998-03-01 00:00:00

abstract：:While risk factors for konzo are known, determinants of cognitive impairment in konzo-affected children remain unknown. We anchored cognitive performance (KABC-II scores) to serum levels of free-thyroxine (free-T4), thyroid-stimulating hormone (TSH), albumin, and motor proficiency (BOT-2 scores) in 40 children includi...

journal_title：Metabolic brain disease

authors： Bumoko GM,Sombo MT,Okitundu LD,Mumba DN,Kazadi KT,Tamfum-Muyembe JJ,Lasarev MR,Boivin MJ,Banea JP,Tshala-Katumbay DD

更新日期：2014-06-01 00:00:00

abstract：:Tyrosinemia type II is a genetic disorder characterized by elevated blood levels of the amino acid tyrosine caused by the deficiency of tyrosine aminotransferase enzyme, resulting in neurologic and developmental difficulties in the patients. Although neurological sequelae are common in Tyrosinemia type II patients, th...

journal_title：Metabolic brain disease

authors： Carvalho-Silva M,Gomes LM,de Prá SD,Wessler LB,Schuck PF,Scaini G,de Bem AF,Blum-Silva CH,Reginatto FH,de Oliveira J,Streck EL

更新日期：2020-01-01 00:00:00

abstract：:Transient cerebral ischemia causes long-lasting inhibition of protein synthesis despite recovery of energy metabolism. We investigated the question if this inhibition is due to the formation of a suppression factor which interferes with the function of the protein synthesizing machinery. For this purpose rats were sub...

journal_title：Metabolic brain disease

authors： Erdogdu G,Uto A,Hossmann KA

更新日期：1993-12-01 00:00:00

abstract：:Antipsychotics, such as risperidone, increase food intake and induce alteration in glucose and lipid metabolism concomitantly with overweight and body fat increase, these biological abnormalities belong to the metabolic syndrome definition (high visceral adiposity, hypertriglyceridemia, hyperglycemia, low HDL-choleste...

journal_title：Metabolic brain disease

authors： Auger F,Martin F,Pétrault O,Samaillie J,Hennebelle T,Trabelsi MS,Bailleul F,Staels B,Bordet R,Duriez P

更新日期：2018-02-01 00:00:00

abstract：:Traumatic brain injury (TBI) is accompanied with enhanced matrix metalloproteinase-9 (MMP-9) activity and elevated levels of plasma fibrinogen (Fg), which is a known inflammatory agent. Activation of MMP-9 and increase in blood content of Fg (i.e. hyperfibrinogenemia, HFg) both contribute to cerebrovascular disorders ...

journal_title：Metabolic brain disease

authors： Muradashvili N,Benton RL,Saatman KE,Tyagi SC,Lominadze D

更新日期：2015-04-01 00:00:00

abstract：:Attention alterations are reported in cirrhotics. Aiming at clarifying attention functioning in cirrhotics, an inquiry on the functioning of the anterior (AAS) and the posterior (PAS) attention system was performed. Thirty-six cirrhotics without overt hepatic encephalopathy (24 with EEG or TMT-A alterations) and 16 ma...

journal_title：Metabolic brain disease

authors： Amodio P,Schiff S,Del Piccolo F,Mapelli D,Gatta A,Umiltà C

更新日期：2005-06-01 00:00:00

abstract：:In this work, we evaluated the effects of Psidium cattleianum (Red Type) (PcRT) fruit extract on metabolic, behavioral, and neurochemical parameters in rats fed with a highly palatable diet (HPD) consisted of sucrose (65% carbohydrates being 34% from condensed milk, 8% from sucrose and 23% from starch, 25% protein and...

journal_title：Metabolic brain disease

authors： Oliveira PS,Chaves VC,Soares MSP,Bona NP,Mendonça LT,Carvalho FB,Gutierres JM,Vasconcellos FA,Vizzotto M,Vieira A,Spanevello RM,Reginatto FH,Lencina CL,Stefanello FM

更新日期：2018-10-01 00:00:00

abstract：:Because of the importance of cholesterol metabolism in the physiopathogenesis of dementia, and knowing the function of ATP-binding cassette A1 transporter (ABCA1) as a cholesterol flow pump at the cellular and cerebral level, it has been noted that the ABCA1 gene may be a good candidate for disease study. In order to ...

journal_title：Metabolic brain disease

authors： Teresa JC,Fernado C,Nancy MR,Gilberto VA,Alberto CR,Roberto RR

更新日期：2020-08-01 00:00:00

abstract：:Hepatic encephalopathy is a common complication of hepatic cirrhosis. The clinical diagnosis is based on two concurrent types of symptoms: impaired mental status and impaired neuromotor function. Impaired mental status is characterized by deterioration in mental status with psychomotor dysfunction, impaired memory, an...

journal_title：Metabolic brain disease

authors： Malaguarnera M

更新日期：2013-06-01 00:00:00