Neuron-glial relationship during regeneration of motorneurons.

abstract：:Increased benzodiazepine (BZ) receptor density has been reported in brains of rabbits with hepatic encephalopathy (HE) due to galactosamine (GalN)-induced fulminant hepatic failure (FHF). These data were generated using detergent-Triton X-100-treated neural membranes. While performing further studies it was noted that...

journal_title：Metabolic brain disease

authors： Rössle M,Mullen KD,Jones EA

更新日期：1989-09-01 00:00:00

abstract：:The developing facial neurons of a series of hamsters ranging in age from the 14-day fetus to the 9 day postnatal were axotomized. Postoperative times were graded for each age so that the retrograde response could be observed before any significant amount of cell degeneration or death occurred. The incorporation of tr...

journal_title：Metabolic brain disease

authors： Clark P,Jones KJ,LaVelle A

更新日期：1993-06-01 00:00:00

abstract：:Because of the importance of cholesterol metabolism in the physiopathogenesis of dementia, and knowing the function of ATP-binding cassette A1 transporter (ABCA1) as a cholesterol flow pump at the cellular and cerebral level, it has been noted that the ABCA1 gene may be a good candidate for disease study. In order to ...

journal_title：Metabolic brain disease

authors： Teresa JC,Fernado C,Nancy MR,Gilberto VA,Alberto CR,Roberto RR

更新日期：2020-08-01 00:00:00

abstract：:Heart failure patients often manifest white matter hyperintensites on brain magnetic resonance imaging (MRI). White matter hyperintnsities have also been linked with cognitive problems in patients with heart failure. Sleep disordered breathing may contribute to structural brain changes in heart failure. The purpose of...

journal_title：Metabolic brain disease

authors： Moon C,Bendlin BB,Melah KE,Bratzke LC

更新日期：2018-12-01 00:00:00

abstract：:The heterogeneity of monoamine oxidase (MAO; EC 1.4.3.4) activities was studied in two fractions of synaptic mitochondria (SM & SM2) and one fraction of non-synaptic ("free") mitochondria (M) isolated from three rat brain regions (cerebral cortex, striatum, and pons & medulla) by the Lai and Clark (1979, 1989) method ...

journal_title：Metabolic brain disease

authors： Lai JC,Leung TK,Lim L

更新日期：1994-03-01 00:00:00

abstract：:Current data on the neurotrophic effects of steroid hormones suggest that, in brain and spinal cord regions containing receptor systems, steroids act at the level of RNA and protein synthesis to effect metabolic changes associated with nerve-cell survival, elaboration/maintenance of dendritic and axonal processes, syn...

journal_title：Metabolic brain disease

authors： Jones KJ

更新日期：1988-03-01 00:00:00

abstract：:To investigate the hypothesis that neurotoxic metals can exert their toxicity through the direct inhibition of monoamine oxidases (MAOs), the effects of several neurotoxic metal ions on type A (MAO-A) and type B (MAO-B) monoamine oxidase activities in rat forebrain nonsynaptic mitochondria and rat liver mitochondria w...

journal_title：Metabolic brain disease

authors： Leung TK,Lim L,Lai JC

更新日期：1992-09-01 00:00:00

abstract：:MRPS22 gene defect is a very rare newly discovered mitochondrial disorder. We report a 4-month-old severely affected male infant with MRPS22 mutation. Whole exome sequencing revealed a novel homozygous splicing mutation c.339 + 5 G > A in MRPS22 gene. He has mild dysmorphism, hypotonia, developmental delay but not hyp...

journal_title：Metabolic brain disease

authors： Kılıç M,Oğuz KK,Kılıç E,Yüksel D,Demirci H,Sağıroğlu MŞ,Yücel-Yılmaz D,Özgül RK

更新日期：2017-10-01 00:00:00

abstract：:Iron is an important micronutrient for neuronal function and survival. It plays an essential role in DNA and protein synthesis, neurotransmission and electron transport chain due to its dual redox states. On the contrary, iron also catalyses the production of free radicals and hence, causes oxidative stress. Therefore...

journal_title：Metabolic brain disease

authors： Minhas G,Modgil S,Anand A

更新日期：2014-09-01 00:00:00

abstract：:There is evidence to suggest that, in acute liver failure (ALF), brain ammonia and proinflammatory cytokines may act synergistically to cause brain edema and its complications (intracranial hypertension, brain herniation). However, the molecular mechanisms involved remain to be established. In order to address this is...

journal_title：Metabolic brain disease

authors： Chastre A,Jiang W,Desjardins P,Butterworth RF

更新日期：2010-03-01 00:00:00

abstract：:Oxidative stress is strongly implicated in the pathogenesis of stroke. Strategies using antioxidants to improve neurological functions after stroke have, thus, gained significant attention. Ocimum basilicum L. is used traditionally to treat CNS disorders. Its antioxidant capacity is well established. Our laboratory ha...

journal_title：Metabolic brain disease

authors： Singh V,Krishan P,Shri R

更新日期：2018-08-01 00:00:00

abstract：:Hepatic encephalopathy (HE) represents a nervous system disorder caused due to liver dysfunction. HE is broadly classified as acute/overt and moderate-minimal HE. Since HE syndrome severely affects quality of life of the patients and it may be life threatening, it is important to develop effective therapeutic strategy...

journal_title：Metabolic brain disease

authors： Mondal P,Trigun SK

更新日期：2014-12-01 00:00:00

abstract：:The present work was carried out to study the influence of ammonia and factors from sera and cerebrospinal fluid (CSF) from patients with different degrees of chronic liver diseases on [3H]D-aspartate (Asp) and [3H]L-glutamate (Glu) high-affinity uptake into the rat hippocampal formation. For comparison, high-affinity...

journal_title：Metabolic brain disease

authors： Schmidt W,Wolf G,Grüngreiff K,Meier M,Reum T

更新日期：1990-03-01 00:00:00

abstract：:Glutaric aciduria type I (GA-I) is an inborn error of lysine and tryptophan metabolism. Clinical manifestations of GA-I include dystonic or dyskinetic cerebral palsy, but when the symptoms occur, treatment is not effective. In Taiwan, newborn screening for GA-I started in 2001; we wish to evaluate the outcomes of pati...

journal_title：Metabolic brain disease

authors： Lee CS,Chien YH,Peng SF,Cheng PW,Chang LM,Huang AC,Hwu WL,Lee NC

更新日期：2013-03-01 00:00:00

abstract：:There is substantial clinical and experimental evidence that ammonia is a major factor in the pathogenesis of hepatic encephalopathy. In the article is demonstrated that in hepatocellular dysfunction, ammonia detoxification to glutamine (GLN) in skeletal muscle, brain, and likely the lungs, is activated. In addition t...

journal_title：Metabolic brain disease

authors： Holecek M

更新日期：2014-03-01 00:00:00

abstract：:Cyclic AMP is part of an endogenous mechanism that downregulates inflammatory response, and its intracellular concentration is regulated chiefly by cyclic nucleotide phosphodiesterases type 4. The goal of the present study was to determine whether phosphodiesterases 4 are involved in the inflammatory response of astro...

journal_title：Metabolic brain disease

authors： Borysiewicz E,Fil D,Dlaboga D,O'Donnell JM,Konat GW

更新日期：2009-09-01 00:00:00

abstract：:Today, neurological disorders such as epilepsy, depression, tardive dyskinesia, and stress, and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, dementia, and Huntington's disease affect millions of people all over the world. Existing pharmacological interventions do not meet the desired t...

journal_title：Metabolic brain disease

authors： Husain I,Zameer S,Madaan T,Minhaj A,Ahmad W,Iqubaal A,Ali A,Najmi AK

更新日期：2019-08-01 00:00:00

abstract：:Sepsis is a major clinical challenge that is associated with encephalopathy and multi-organ dysfunction. Current therapeutic interventions are relatively ineffective and the development of novel treatments is hampered by the lack of a well-characterised animal model. Therefore, the behavioural, metabolic, physiologica...

journal_title：Metabolic brain disease

authors： Brooks HF,Osabutey CK,Moss RF,Andrews PL,Davies DC

更新日期：2007-12-01 00:00:00

abstract：:As feared and deadly human diseases globally, Rabies virus contrived mechanisms to escape early immune recognition via suppression of the interferon response. This study, preliminarily investigated whether Rabies virus employs epigenetic mechanism for the suppression of the interferon using the Challenge virus standar...

journal_title：Metabolic brain disease

authors： Abdulazeez M,Kia GSN,Abarshi MM,Muhammad A,Ojedapo CE,Atawodi JC,Dantong D,Kwaga JKP

更新日期：2020-06-01 00:00:00

abstract：:The mitogen-activated protein kinase (MAP kinase) pathway participates in a number of reactions of the cell when responding to various external stimuli. These stimuli include growth factor binding to its receptor as well as stressful situations such as hypoxia and oxidative stress. It has been postulated that one of t...

journal_title：Metabolic brain disease

authors： Daniels WM,Hendricks J,Salie R,Taljaard JJ

更新日期：2001-12-01 00:00:00

abstract：:Bilateral, symmetrical hyperintensity of the globus pallidus is observed in T1-weighted cerebral magnetic resonance images in from 52 to 100% of patients with chronic liver disease. No significant relationship exists between the presence of these cerebral changes in image signal intensity and the patients' neuropsychi...

journal_title：Metabolic brain disease

authors： Morgan MY

更新日期：1998-12-01 00:00:00

abstract：:In the original publication of the article, author name Masoumeh Asadbegi was incorrectly written as Masoumeh Asadbeigi. The authors regret the oversight. ...

journal_title：Metabolic brain disease

authors： Sajadi A,Amiri I,Gharebaghi A,Komaki A,Asadbegi M,Shahidi S,Mehdizadeh M,Asl SS

更新日期：2017-12-01 00:00:00

abstract：:Chronic ethanol ingestion results in an "up-regulation" of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor in mouse brain. This increase in receptors is associated with ethanol withdrawal seizures, which can be attenuated by NMDA receptor antagonists. Chronic exposure to ethanol (3 days) of rat cerebella...

journal_title：Metabolic brain disease

authors： Hoffman PL

更新日期：1995-03-01 00:00:00

abstract：:D-Galactose (D-gal) chronic administration via intraperitoneal and subcutaneous routes has been used as a model of aging and Alzheimer disease in rodents. Intraperitoneal and subcutaneous administration of D-gal causes memory impairments, a reduction in the neurogenesis of adult mice, an increase in the levels of the ...

journal_title：Metabolic brain disease

authors： Budni J,Garcez ML,Mina F,Bellettini-Santos T,da Silva S,Luz APD,Schiavo GL,Batista-Silva H,Scaini G,Streck EL,Quevedo J

更新日期：2017-06-01 00:00:00

abstract：:D-galactose (GAL) causes aging-related changes and oxidative stress in the organism. We investigated the effect of whole fresh blueberry (BB) (Vaccinium corymbosum L.) treatment on oxidative stress in age-related brain damage model. Rats received GAL (300 mg/kg; s.c.; 5 days per week) alone or together with 5 % (BB1) ...

journal_title：Metabolic brain disease

authors： Çoban J,Doğan-Ekici I,Aydın AF,Betül-Kalaz E,Doğru-Abbasoğlu S,Uysal M

更新日期：2015-06-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder, characterized by accumulation and deposition of Aβ peptide in human brain. The present study aimed to determine the protective effect of catechin rich extract of MERM (methanolic extract of Rhizophora mucronata) on Aβ (25-35) induced cognitive impai...

journal_title：Metabolic brain disease

authors： Suganthy N,Malar DS,Devi KP

更新日期：2016-08-01 00:00:00

abstract：:Sevoflurane, one of the most commonly used volatile anesthetics in clinical treatment, has been shown to induce a widespread increase in brain apoptosis. However, the underlying mechanism is still unknown. Sestrin 2 has been recently shown to regulate intracellular reactive oxygen species (ROS) levels and play a cruci...

journal_title：Metabolic brain disease

authors： Yi W,Zhang Y,Guo Y,Li D,Li X

更新日期：2015-10-01 00:00:00

abstract：:Oral glutamine challenge is a method to increase blood ammonia and may be used to study the ammonia lowering effect of drugs potentially useful in hepatic encephalopathy (HE). We tested its influence on the psychometric performance of 18 cirrhotic patients without HE. Twelve nonencephalopatic cirrhotic patients were s...

journal_title：Metabolic brain disease

authors： Masini A,Efrati C,Merli M,Nicolao F,Amodio P,Del Piccolo F,Riggio O

更新日期：2003-03-01 00:00:00

abstract：:The integrity of the blood-brain barrier (BBB) is an important aspect of normal central nervous system (CNS) function. Recently, it was shown that the BBB breakdown is one of the predisposing factors in the pathogenesis of thiamine-deficiency encephalopathy. The result is discussed along with some reviews on previous ...

journal_title：Metabolic brain disease

authors： Harata N,Iwasaki Y

更新日期：1996-03-01 00:00:00

abstract：:Several epidemiological studies have shown that Diabetes Mellitus (DM) or Insulin Resistance (IR) increases the risk of dementia. Besides, some authors suggested that poor glucose control to be associated with worse cognitive function. We aimed to assess cognitive functions and IR-degree over time in diabetic. We also...

journal_title：Metabolic brain disease

authors： Fava A,Colica C,Plastino M,Messina D,Cristiano D,Opipari C,Vaccaro A,Gorgone G,Bosco F,Fratto A,De Bartolo M,Bosco D

更新日期：2017-06-01 00:00:00