Molecular cloning and serological characterization of a new Plasmodium vivax recombinant antigen which contains apolipoprotein B-100 like sequences.

abstract：:We recently demonstrated that proteoglycan macrophage colony-stimulating factor (PG-M-CSF) binds basic fibroblast growth factor (bFGF) and neutralizes the biological activity of bFGF. In this study, we identified the binding sites of PG-M-CSF for bFGF. We examined the binding of bFGF to overlapping 12-mer peptides wit...

journal_title：Biochemical and biophysical research communications

authors： Suzu S,Kimura F,Matsumoto H,Yamada M,Hashimoto K,Shimamura S,Motoyoshi K

更新日期：1997-01-13 00:00:00

abstract：:While Aspergillus ficuum phytaseA (phyA) was rapidly inactivated by 1,2-cyclohexanedione and phenylglyoxal, both specific modifiers of arginine, phytaseB (phyB) showed a markedly different behavior. First, phyB was totally insensitive to 1,2-cyclohexanedione even in the presence of 0.2 M guanidinium hydrochloride; sec...

journal_title：Biochemical and biophysical research communications

authors： Ullah AH,Sethumadhavan K

更新日期：1998-02-13 00:00:00

abstract：:We have constructed a highly useful phage-displayed human antibody repertoire with limited cloning efforts. Our strategy was to maximize diversity during the first steps of library construction through the use of various lymphoid sources from several donors, inclusion of different immunoglobulin isotypes, and performa...

journal_title：Biochemical and biophysical research communications

authors： Rojas G,Lamdan H,Padron S,Munoz Y,Ayala M,Gavilondo JV

更新日期：2005-11-04 00:00:00

abstract：:Organoids mimicking the formation of the brain cortex have been demonstrated to be powerful tools for developmental studies as well as pathological investigations of brain malformations. Here, we report an integrated approach for the quantification of temporal neural production (neurogenic rate) in organoids derived f...

journal_title：Biochemical and biophysical research communications

authors： Kosodo Y,Suetsugu T,Kobayashi TJ,Matsuzaki F

更新日期：2017-01-29 00:00:00

abstract：:Astrocyte elevated gene-1 (AEG-1), upregulated in various types of malignancies including colorectal cancer (CRC), has been reported to be associated with the carcinogenesis. MicroRNAs (miRNAs) are widely involved in the initiation and progression of cancer. However, the functional significance of AEG-1 and the relati...

journal_title：Biochemical and biophysical research communications

authors： Huang S,Wu B,Li D,Zhou W,Deng G,Zhang K,Li Y

更新日期：2014-02-14 00:00:00

abstract：:The p53 homologue p73 is expressed in at least six different isoforms (alpha, beta, gamma, delta, epsilon, and zeta), but unlike p53 it has rarely been found mutated in human cancers. However, altered expression of this gene has been reported in cancer cells. In order to understand if p73 is involved in normal and mal...

journal_title：Biochemical and biophysical research communications

authors： Tschan MP,Grob TJ,Peters UR,Laurenzi VD,Huegli B,Kreuzer KA,Schmidt CA,Melino G,Fey MF,Tobler A,Cajot JF

更新日期：2000-10-14 00:00:00

abstract：:The antiherpetic agent 9-beta-D-arabinofuranosyladenine (araA) needs to be phosphorylated to its 5'-triphosphate to be effective as an inhibitor of herpes simplex virus replication. Adenosine kinase and deoxycytidine kinase are assumed to convert araA to its 5'-monophosphate. We now found that araAMP is converted to i...

journal_title：Biochemical and biophysical research communications

authors： Balzarini J,De Clercq E

更新日期：1990-12-31 00:00:00

abstract：:Osterix (Osx) is an essential transcription factor required for osteoblast differentiation during both intramembranous and endochondral ossification. Endochondral ossification, a process in which bone formation initiates from a cartilage intermediate, is crucial for skeletal development and growth. Osx is expressed in...

journal_title：Biochemical and biophysical research communications

authors： Oh JH,Park SY,de Crombrugghe B,Kim JE

更新日期：2012-02-24 00:00:00

abstract：:It is well known that the expression of osteocalcin, the only recognized osteoblast-specific protein, is regulated by 1 alpha-25-dihydroxyvitamin D3 through a distinct vitamin D3 receptor and a cis-acting DNA response element. In addition, recent data obtained with plasmid constructs have shown a positive interaction ...

journal_title：Biochemical and biophysical research communications

authors： Oliva A,Della Ragione F,Fratta M,Marrone G,Palumbo R,Zappia V

更新日期：1993-03-31 00:00:00

abstract：:Differential expression of nuclear factors binding specifically to AP-1, AP-2, AP-3, and NF-I/CTF enhancer elements was found in the various cell types of human lung carcinoma cells. Adenocarcinoma and squamous carcinoma cells seemed to express higher levels of these factors than large-cell carcinoma and small-cell ca...

journal_title：Biochemical and biophysical research communications

authors： Wong YC,Bernal SD

更新日期：1991-10-31 00:00:00

abstract：:The understanding of capsid (C) protein interactions with itself would provide important data on how the core is organized in flaviviruses during assembly. In this study, West Nile (WN) virus C protein was shown to form homodimers using yeast two-hybrid analysis in conjunction with mammalian two-hybrid and in vivo co-...

journal_title：Biochemical and biophysical research communications

authors： Bhuvanakantham R,Ng ML

更新日期：2005-04-01 00:00:00

abstract：:Immediately from the outset of the COVID-19 pandemic, researchers from diverse biomedical and biological disciplines have united to study the novel pandemic virus, SARS-CoV-2. The antibody response to SARS-CoV-2 has been a major focus of COVID-19 research due to its clinical relevance and importance in vaccine and the...

journal_title：Biochemical and biophysical research communications

authors： Yuan M,Liu H,Wu NC,Wilson IA

更新日期：2020-10-10 00:00:00

abstract：:Fifteen pancreatic secretory proteins, including seven serine-endoproteinases (isoenzyme forms of trypsinogen, chymotrypsinogen and proelastase), four metallo-exoproteinases (isoenzymic forms of procarboxypeptidase A and procarboxypeptidase B), amylase, lipase, and two forms of carboxyl ester lipase were observed to a...

journal_title：Biochemical and biophysical research communications

authors： Freedman SD,Scheele GA

更新日期：1993-12-15 00:00:00

abstract：:Platelet-derived growth factor-D (PDGF-D) is a more recent recognized growth factor involved in the regulation of several cellular processes, including cell proliferation, transformation, invasion, and angiogenesis by binding to and activating its cognate receptor PDGFR-β. After bile duct ligation or in the carbon tet...

journal_title：Biochemical and biophysical research communications

authors： Borkham-Kamphorst E,Alexi P,Tihaa L,Haas U,Weiskirchen R

更新日期：2015-02-13 00:00:00

abstract：:When human ovarian carcinoma cells are challenged with endotoxin, an I kappa B kinase is transiently induced within 3 to 5 min. This enzyme activity causes the hyperphosphorylation and subsequent degradation of I kappa B which allows NF-kappa B to translocate to the nucleus where it activates transcription. When endot...

journal_title：Biochemical and biophysical research communications

authors： Kohler NG,Joly A

更新日期：1997-03-27 00:00:00

abstract：:Discerning oncogenic drivers from passengers remains a major effort in understanding of the essence of the initiation and development of hepatocellular carcinoma (HCC), the most common primary liver malignancy and the third leading cause of cancer mortality worldwide. Here we report that MTA2, Metastasis Associated 1 ...

journal_title：Biochemical and biophysical research communications

authors： Guan C,Chang Z,Gu X,Liu R

更新日期：2019-07-12 00:00:00

abstract：:Neu2 mRNA from the mouse thymus, as we have reported [K. Kotani, A. Kuroiwa, T. Saito, Y. Matsuda, T. Koda, S. Kijimoto-Ochiai, Cloning, chromosomal mapping, and characteristic 5'-UTR sequence of murine cytosolic sialidase, Biochem. Biophys. Res. Commun. 286 (2001) 250-258], has a novel sequence at the 5' terminus tha...

journal_title：Biochemical and biophysical research communications

authors： Koda T,Kijimoto-Ochiai S,Uemura S,Inokuchi J

更新日期：2009-10-02 00:00:00

abstract：:To understand the regulation by thyroid hormone, 3,3',5-triiodo-L-thyronine (T3), of the synthesis of a cytosolic thyroid hormone binding protein (p58-M2) during liver regeneration, the synthesis of p58-M2 was evaluated. The synthesis of p58-M2 was measured by metabolic labeling of primary cultures derived from the re...

journal_title：Biochemical and biophysical research communications

authors： Obata T,Cheng SY

更新日期：1992-11-30 00:00:00

abstract：:A novel hemoglobin variant was detected by electrospray ionization mass spectrometry. Hb Zurich-Hottingen is characterized by an Asn --> Ser replacement in the alpha-chain at position 9 as confirmed by DNA analysis. This hemoglobin variant is silent in isoelectric focusing, reversed-phase chromatography, and cation-ex...

journal_title：Biochemical and biophysical research communications

authors： Troxler H,Neuheiser F,Kleinert P,Kuster T,Heizmann CW,Sack R,Hunziker P,Neuhaus TJ,Schmid M,Frischknecht H

更新日期：2002-04-12 00:00:00

abstract：:Tumor promoting phorbol esters inhibited the binding of 125I-[Tyr11] somatostatin to isolated acinar cells from guinea-pig pancreas. Maximal inhibition reached 69.7 +/- 5% at 1 microM TPA. Receptor affinity was decreased by 2.5-fold without change in binding capacity. The ability of TPA in inhibiting somatostatin bind...

journal_title：Biochemical and biophysical research communications

authors： Zeggari M,Susini C,Viguerie N,Esteve JP,Vaysse N,Ribet A

更新日期：1985-04-30 00:00:00

abstract：:When several DNAs are amplified by PCR in one PCR tube, biased amplification is known to occur because amplification efficiency differs from one DNA to another. Therefore, we conducted PCR in the water in oil-emulsion (W/O emulsion) to examine whether the procedure allows the uniform amplification of several DNAs. In ...

journal_title：Biochemical and biophysical research communications

authors： Hori M,Fukano H,Suzuki Y

更新日期：2007-01-12 00:00:00

abstract：:Transgenic animals were used to examine the spatial and temporal regulation of the human beta amyloid precursor protein (APP) gene promoter region in vivo. A 2.9 kb DNA fragment encompassing the APP gene promoter was fused to the chloramphenical acetyltransferase (CAT) reporter gene (pAMY-CAT) or a partial cDNA encodi...

journal_title：Biochemical and biophysical research communications

authors： Fox NW,Johnstone EM,Ward KE,Schrementi J,Little SP

更新日期：1997-11-26 00:00:00

abstract：:Previously it was known that cytosolic Ca(2+) elevation was involved in regulating UV- or TNFalpha-induced apoptosis. Here, we reported new evidence that mitochondrial Ca(2+) signal is also involved in the apoptotic process. First, using living cell imaging techniques, we observed multiple mitochondrial Ca(2+) spikes ...

journal_title：Biochemical and biophysical research communications

authors： Lao Y,Chang DC

更新日期：2008-08-15 00:00:00

abstract：:The new bacterial vector pETM60 enables the expression of His-tagged recombinant proteins fused to the C-terminus of NusA through a TEV protease recognition sequence. Three sequences coding for two protein domains (Xklp3A and Tep3Ag) and one membrane-bound viral protein (E8R) could not be expressed in a soluble form i...

journal_title：Biochemical and biophysical research communications

authors： De Marco V,Stier G,Blandin S,de Marco A

更新日期：2004-09-24 00:00:00

abstract：:Polymerization of actin induced by activation of platelets was investigated using deoxyribonuclease I inhibition assay. When platelets were activated with ADP or 5-hydroxytryptamine, actin was polymerized quickly followed by rapid depolymerization to the initial level. Reactivation with the same agonist, however, did ...

journal_title：Biochemical and biophysical research communications

authors： Imada T,Kikuchi T,Shimada H,Inada Y,Saito Y

更新日期：1984-05-16 00:00:00

abstract：:Trilobolide and 2,5-di(tert-butyl)-1,4-benzohydroquinone (BHQ) are potent inhibitors of the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum. Desoxytrilobolide and 2,5-di(tert-butyl)-1,4-diacetylphenol (acetyl-BHQ) have much lower potencies than their parent compounds and 2,5-di(tert-butyl)-1,4-benzoquinone (BQ...

journal_title：Biochemical and biophysical research communications

authors： Wictome M,Holub M,East JM,Lee AG

更新日期：1994-03-15 00:00:00

abstract：:Human adipose-derived mesenchymal stem cells (hASCs) are attractive cell source for skin tissue engineering. The aim of this study was to investigate the effects of low-level light therapy (LLLT) on transplanted cluster hASC in a skin wound animal model. The hASCs were cultured in monolayer or clusters. The LLLT, hASC...

journal_title：Biochemical and biophysical research communications

authors： Park IS,Chung PS,Ahn JC

更新日期：2015-07-03 00:00:00

abstract：:We previously demonstrated that the translocation of phospholipids between the mitochondrion and the endoplasmic reticulum occurs via highly specialized membrane microdomains of both organelles that are in situ closely associated. As understanding of the interactions between both organelles requires characterization o...

journal_title：Biochemical and biophysical research communications

authors： Gasnier F,Ardail D,Febvay G,Simonot C,Lerme F,Guillaud J,Louisot P,Gateau-Roesch O

更新日期：1993-09-30 00:00:00

abstract：:The activation of vitamin D requires 25-hydroxylation in the liver and 1alpha-hydroxylation in the kidney. However, it remains unclear which enzyme is relevant to vitamin D 25-hydroxylation. Recently, human CYP2R1 has been reported to be a potential candidate for a hepatic vitamin D 25-hydroxylase. Thus, vitamin D met...

journal_title：Biochemical and biophysical research communications

authors： Shinkyo R,Sakaki T,Kamakura M,Ohta M,Inouye K

更新日期：2004-11-05 00:00:00

abstract：:Six healthy subjects were given endothelin-1, intravenously in a dose of 4 pmol.kg-1.min-1 for 20 min. Blood samples were drawn from arterial, hepatic and renal vein catheters for determinations of splanchnic and renal blood flows and the extraction of endothelin-1 in these vascular beds. Intravenous infusion of endot...

journal_title：Biochemical and biophysical research communications

authors： Weitzberg E,Ahlborg G,Lundberg JM

更新日期：1991-11-14 00:00:00