Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies.

abstract：:Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that ...

journal_title：Biochemical and biophysical research communications

authors： Fu J,Xu X,Kang L,Zhou L,Wang S,Lu J,Cheng L,Fan Z,Yuan B,Tian P,Zheng X,Yu C,Ye Q,Lv Z

更新日期：2014-03-07 00:00:00

abstract：:Tocopherols (vitamin E) located in the hydrophobic domains of biological membranes act as chain breaking antioxidants preventing the propagation of free radical reactions of lipid peroxidation. The naturally occurring form, d-alpha tocopherol is an exquisite molecule in that it is intercalated in the membrane in such ...

journal_title：Biochemical and biophysical research communications

authors： Stoyanovsky DA,Kagan VE,Packer L

更新日期：1989-04-28 00:00:00

abstract：:Of two major isoforms of angiotensin II receptors, AT1 and AT2, biological roles of AT2 remain unclear. Using vascular smooth muscle cells, we investigated the regulation of expression of AT2 by growth factors in comparison with that of AT1. The cultured rat aorta smooth muscle cells had detectable AT2 binding sites, ...

journal_title：Biochemical and biophysical research communications

authors： Kambayashi Y,Bardhan S,Inagami T

更新日期：1993-07-15 00:00:00

abstract：:A protein designated mungin, isolated from mung bean (Phaseolus mungo) seeds, possessed activity against the fungi Rhizoctonia solani, Coprinus comatus, Mycosphaerella arachidicola, Botrytis cinerea, and Fusarium oxysporum. The 18-kDa protein also possessed a novel N-terminal sequence with similarity to cyclophilins. ...

journal_title：Biochemical and biophysical research communications

authors： Ye XY,Ng TB

更新日期：2000-07-14 00:00:00

abstract：:The effect of endothelin (ET) on the cytosolic-free calcium [(Ca2+]i) changes in polymorphonuclear leukocytes (PMN) from normal humans and Wistar rats was investigated. ET induced a dose-related [Ca2+]i peak. This [Ca2+]i transient was blunted by TMB-8 (10(-5)M) and by Ca(2+)-free EGTA medium, therefore suggesting a r...

journal_title：Biochemical and biophysical research communications

authors： Lopez Farre A,Riesco A,Moliz M,Egido J,Casado S,Hernando L,Caramelo C

更新日期：1991-08-15 00:00:00

abstract：:Multiple types of connexin (Cxs) products, including Cx26, Cx30, Cx31, and Cx43, are found by immunolabeling in the mature cochlea. The transcript of Cx29, a newly discovered member of Cx gene family, was also discovered in the cochlea by cDNA macroarray hybridization. However, the functional roles of Cx29 in the coch...

journal_title：Biochemical and biophysical research communications

authors： Yang JJ,Liao PJ,Su CC,Li SY

更新日期：2005-12-16 00:00:00

abstract：:Endosomal trafficking of EGF receptor (EGFR) upon stimulation is a highly regulated process during receptor-mediated signaling. Recently, the sorting nexin (SNX) family has emerged as an important regulator in the membrane trafficking of EGFR. Here, we report the identification of a novel interaction between two membe...

journal_title：Biochemical and biophysical research communications

authors： Liu H,Liu ZQ,Chen CX,Magill S,Jiang Y,Liu YJ

更新日期：2006-04-07 00:00:00

abstract：:This article has been withdrawn at the request of the editors. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Achour M,Mousli M,Alhosin M,Ibrahim A,Peluso J,Muller CD,Schini-Kerth VB,Hamiche A,Dhe-Paganon S,Christian Bronner

更新日期：2012-07-04 00:00:00

abstract：:Interleukin 6 is a cytokine with growth and differentiation activities on a number of cell types. Human articular chondrocytes produce interleukin 6 and this production appears to be constitutive but can be stimulated in a dose-dependent manner by interleukin 1. Other stimulators of interleukin 6 production in chondro...

journal_title：Biochemical and biophysical research communications

authors： Bunning RA,Russell RG,Van Damme J

更新日期：1990-02-14 00:00:00

abstract：:The aim of this study is to investigate the mechanism underling cardiac dysfunction during sepsis, as well as the possible amelioration of this dysfunction by exogenous carbon monoxide (CO) administration. For this purpose, rats (six-week-old, male, Sprague-Dawley) were administered LPS (15 mg/kg body weight, i.p. 6 h...

journal_title：Biochemical and biophysical research communications

authors： Unuma K,Aki T,Nagano S,Watanabe R,Uemura K

更新日期：2018-01-08 00:00:00

abstract：:Helodermin belongs to the VIP family of polypeptides. Recent in vivo data suggest that helodermin-like peptides might be involved in the regulation of calcium metabolism. We show that helodermin specifically binds to a secretin-type receptor in osteoblast-like cells from fetal rat calvaria and increases the basal and ...

journal_title：Biochemical and biophysical research communications

authors： Pfeilschifter J,Naumann A,Oechsner M,Ziegler R

更新日期：1990-07-31 00:00:00

abstract：:Having ascertained using JC-1 as a probe that, in distinction with the controls, during capacitation boar sperm maintains high mitochondrial membrane potential (ΔΨ), to gain some insight into the role of mitochondria in capacitation, we monitored ΔΨ generation due to externally added metabolites either in hypotonicall...

journal_title：Biochemical and biophysical research communications

authors： Paventi G,Lessard C,Bailey JL,Passarella S

更新日期：2015-07-03 00:00:00

abstract：:RegIIIβ and RegIIIγ are antimicrobial peptides expressed in intestinal epithelial cells. Expression of these peptides is reportedly decreased by high-fat diet (HFD) and increased by indigestible oligosaccharides in mice. Clearly, these dietary regimens change the structure of intestinal microbiota. We employed an inte...

journal_title：Biochemical and biophysical research communications

authors： Udomsopagit T,Miwa A,Seki M,Shimbori E,Kadota Y,Tochio T,Sonoyama K

更新日期：2020-08-13 00:00:00

abstract：:Disproportionate hyperproinsulinemia is an indicator of β-cell dysfunction in diabetes and the basis underlying this abnormality remains obscure. Recently, we have found proinsulin is an aggregation-prone molecule inherent with a low relative folding rate and maintains a homeostatic balance of natively and plentiful n...

journal_title：Biochemical and biophysical research communications

authors： Wang J,Osei K

更新日期：2011-07-22 00:00:00

abstract：:A phospholipase A2, which is immuno-crossreactive with the anti-rat pancreatic phospholipase A2 antibody, is present in rat gastric mucosa. The content of the enzyme in the gastric mucosa was comparable to that in the pancreas, but the specific activity in the gastric mucosa homogenate (60.7 +/- 19.5 nmol/min/mg) was ...

journal_title：Biochemical and biophysical research communications

authors： Tojo H,Ono T,Okamoto M

更新日期：1988-03-30 00:00:00

abstract：:Phospholipase D has been implicated as an important enzyme in a range of cellular responses, including regulated secretion and the formation of secretory vesicles, cell proliferation and control of cell morphology. As insulin treatment of adipocytes has been shown to stimulate a phosphatidylcholine-specific phospholip...

journal_title：Biochemical and biophysical research communications

authors： Millar CA,Jess TJ,Saqib KM,Wakelam MJ,Gould GW

更新日期：1999-01-27 00:00:00

abstract：:The physiological importance of the intestinal plasma membrane calcium pump, isoform 1, (Pmca1, Atp2b1), in calcium absorption and homeostasis has not been previously demonstrated in vivo. Since global germ-line deletion of the Pmca1 in mice is associated with embryonic lethality, we selectively deleted the Pmca1 in i...

journal_title：Biochemical and biophysical research communications

authors： Ryan ZC,Craig TA,Filoteo AG,Westendorf JJ,Cartwright EJ,Neyses L,Strehler EE,Kumar R

更新日期：2015-11-06 00:00:00

abstract：:Homologous species specificity is demonstrated with bovine and human thyroglobulin in which the two terminal sugars of the B carbohydrate chain, sialic acid and galactose have been removed by enzymatic hydrolysis. The species specificity is demonstrated by measuring the ability of the deglycosylated thyroglobulin deri...

journal_title：Biochemical and biophysical research communications

authors： Rotella CM,Tanini A,Consiglio E,Shifrin S,De Luca M,Toccafondi R,Kohn LD

更新日期：1983-08-12 00:00:00

abstract：:It has been proposed that the estrogen receptor bears proteolytic activity responsible for its own transformation. This activity was inhibited by aprotinin. Incubation of transformed ER with aprotinin modified the proteolytic digestion of the hormone binding subunit by proteinase K. The smallest hormone-binding fragme...

journal_title：Biochemical and biophysical research communications

authors： Nigro V,Medici N,Abbondanza C,Minucci S,Moncharmont B,Molinari AM,Puca GA

更新日期：1990-07-31 00:00:00

abstract：:Sinusoidal endothelial cells proliferate following hepatocyte regeneration in the liver after partial resection. The expressions of vascular endothelial growth factor (VEGF) and its receptors, flt-1 and KDR/flk-1, were studied by Northern blotting in isolated rat liver cells and 70% resected rat liver. VEGF was expres...

journal_title：Biochemical and biophysical research communications

authors： Mochida S,Ishikawa K,Inao M,Shibuya M,Fujiwara K

更新日期：1996-09-04 00:00:00

abstract：:To investigate the involvement of nitric oxide (NO) in the pathogenesis of the cardiovascular system with aging, we studied the basal release of NO in cultured endothelial cells isolated from normal human umbilical veins (HUVECs) at different population doubling levels (PDLs). The release of NO was assayed by a newly ...

journal_title：Biochemical and biophysical research communications

authors： Sato I,Morita I,Kaji K,Ikeda M,Nagao M,Murota S

更新日期：1993-09-15 00:00:00

abstract：:Phosphoglycerate mutase is inactivated by butanedione in borate buffer. Inactivation by 0.13 mM reagent correlates with the modification of one arginyl residue per subunit, and is prevented by either 2, 3-diphosphoglycerate or 3-phosphoglycerate. With 0.50 mM butanedione, inactivation is accompanied by the modificatio...

journal_title：Biochemical and biophysical research communications

authors： Borders CL Jr,Wilson BA

更新日期：1976-12-20 00:00:00

abstract：:A novel application of atomic force microscopy (AFM) in the rapid, label-free detection and identification of viruses is described. Multiplexed, miniaturized antibody domains were constructed using "ink-jet" protein arraying technology. The solid-phase affinity substrate termed the "ViriChip" was used in the immunocap...

journal_title：Biochemical and biophysical research communications

authors： Nettikadan SR,Johnson JC,Mosher C,Henderson E

更新日期：2003-11-14 00:00:00

abstract：:A dot-blot hybridization procedure with synthetic oligonucleotide probes is reported, which allows the quantitative titration in genomic DNA of variant forms of repeated genes differing by a single nucleotide change. It involves the utilization of a pair of 22-base long oligonucleotides matching the two variant sequen...

journal_title：Biochemical and biophysical research communications

authors： Nicoloso M,Liang HQ,Bachellerie JP

更新日期：1989-03-31 00:00:00

abstract：:Poly(ADP-ribose) glycohydrolase (PARG) is a major enzyme that plays a role in the degradation of poly(ADP-ribose) (PAR). PARG deficiency reportedly sensitizes cells to the effects of radiation. In lung cancer, however, it has not been fully elucidated. Here, we investigated whether PARG siRNA contributes to an increas...

journal_title：Biochemical and biophysical research communications

authors： Nakadate Y,Kodera Y,Kitamura Y,Tachibana T,Tamura T,Koizumi F

更新日期：2013-11-29 00:00:00

abstract：:Bcl-2 plays a pivotal role in the control of cell death and is down-regulated in trichosanthin (TCS)-induced cell apoptosis. Because Bcl-2 expression is regulated by the transcription factor cyclic AMP response element-binding protein (CREB), we investigated the role of CREB activation in TCS-induced Hela cells apopto...

journal_title：Biochemical and biophysical research communications

authors： Wang P,Yan H,Li JC

更新日期：2007-11-09 00:00:00

abstract：:Fructosamine-3-kinase (FN3K) and the more recently discovered fructosamine-3-kinase related protein (FN3KRP) appear to protect proteins from nonenzymatic glycation. To elucidate the patterns of transcriptional regulation of these two genes, we performed in silico comparisons of their promoters along with real-time PCR...

journal_title：Biochemical and biophysical research communications

authors： Conner JR,Beisswenger PJ,Szwergold BS

更新日期：2004-10-22 00:00:00

abstract：:Whether mitochondrial Ca(2+) transport is rapid enough to respond to changes in cytosolic [Ca(2+)] ([Ca(2+)](c)) which occur during excitation-contraction coupling in the heart is controversial; different results wereobtained with different techniques and different species. In this study mitochondrial [Ca(2+)] ([Ca(2+...

journal_title：Biochemical and biophysical research communications

authors： Griffiths EJ

更新日期：1999-09-24 00:00:00

abstract：:Monosomy 7 and interstitial deletions in the long arm of chromosome 7 (-7/7q-) is a common nonrandom chromosomal abnormality found frequently in myeloid disorders including acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML). Using a short probe-based microarray co...

journal_title：Biochemical and biophysical research communications

authors： Asou H,Matsui H,Ozaki Y,Nagamachi A,Nakamura M,Aki D,Inaba T

更新日期：2009-05-29 00:00:00

abstract：:The enzymatic mechanism of a small ribosome-inactivating protein, gamma-momorcharin, purified from the seeds of Momordica charantia, has been characterized. By SDS-polyacrylamide and electrospray ionization mass spectrometry, its molecular weight was measured to be 11,500 daltons which is much lower than other RIPs kn...

journal_title：Biochemical and biophysical research communications

authors： Pu Z,Lu BY,Liu WY,Jin SW

更新日期：1996-12-04 00:00:00