Mungin, a novel cyclophilin-like antifungal protein from the mung bean.

abstract：:Using an oligonucleotide hybridization assay to gain insight into the folding of delta ribozymes, we demonstrate a correlation between their folding and catalytic behavior. Together with recent structural information on the crystal structure of self-cleaved genomic delta ribozyme, in which the L3 loop interacts with J...

journal_title：Biochemical and biophysical research communications

authors： Ananvoranich S,Perreault JP

更新日期：2000-04-13 00:00:00

abstract：:In spite of intensive research, our understanding of the regulation of expression of 5-LO (the key enzyme in the leukotriene metabolism) remains fragmentary. We investigated the effects of dexamethasone on the expression of this gene in a binary model consisting of two clones of the human mast cell line HMC-1, one wit...

journal_title：Biochemical and biophysical research communications

authors： Colamorea T,Di Paola R,Macchia F,Guerrese MC,Tursi A,Butterfield JH,Caiaffa MF,Haeggström JZ,Macchia L

更新日期：1999-11-30 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) is periodically administered to immunocompromised patients together with antimicrobial agents. The evidence that supports the effectiveness of IVIG is mostly based on data from randomized clinical trials; the underlying mechanisms are poorly understood. A recent study revealed that ki...

journal_title：Biochemical and biophysical research communications

authors： Matsuo H,Itoh H,Kitamura N,Kamikubo Y,Higuchi T,Shiga S,Ichiyama S,Kondo T,Takaori-Kondo A,Adachi S

更新日期：2015-08-14 00:00:00

abstract：:Maternally inherited diabetes and deafness (MIDD) is a mitochondrial syndrome characterized by the onset of sensorineural hearing loss and diabetes in adults. Some patients may have other additional clinical features common in mitochondrial disorders such as pigmentary retinopathy, ptosis, cardiomyopathy, myopathy and...

journal_title：Biochemical and biophysical research communications

authors： Mezghani N,Mnif M,Mkaouar-Rebai E,Kallel N,Charfi N,Abid M,Fakhfakh F

更新日期：2013-02-22 00:00:00

abstract：:The interactions of platelets and liposomes with the tripeptide arginine-glycine-aspartic acid (RGD) as a surface ligand (RGD liposomes) were studied. The results suggest that the presence of the RGD ligand on the liposomes results in receptor-mediated mixing of lipid and aqueous contents of the liposomes and platelet...

journal_title：Biochemical and biophysical research communications

authors： Nishiya T,Sloan S

更新日期：1996-07-05 00:00:00

abstract：:Corticosterone methyloxidase I (CMO I) deficiency is an autosomal recessive disorder of aldosterone biosynthesis. To determine further the molecular genetic basis of CMO I deficiency, a patient of Turkish origin that suffered from CMO I deficiency was studied. Nucleotide sequencing of the PCR-amplified exons from the ...

journal_title：Biochemical and biophysical research communications

authors： Nomoto S,Massa G,Mitani F,Ishimura Y,Miyahara K,Toda K,Nagano I,Yamashiro T,Ogoshi S,Fukata J,Onishi S,Hashimoto K,Doi Y,Imura H,Shizuta Y

更新日期：1997-05-19 00:00:00

abstract：:Taxol (paclitaxel), a microtubule stabilizer with antitumor activity, mimics the actions of lipopolysaccharide (LPS) on murine macrophages (M phi). In the present study, a variety of synthetic analogs of paclitaxel were examined for their potencies to induce nitric oxide (NO) and tumor necrosis factor (TNF) production...

journal_title：Biochemical and biophysical research communications

authors： Kirikae T,Ojima I,Kirikae F,Ma Z,Kuduk SD,Slater JC,Takeuchi CS,Bounaud PY,Nakano M

更新日期：1996-10-03 00:00:00

abstract：:Time-dependent secretion of immunoreactive-endothelin (IR-ET) from cultured porcine aortic endothelial cells was markedly suppressed by phosphoramidon is due to proteinase inhibitor. Analysis of the culture supernatant with or without phosphoramidon by reverse-phase high performance liquid chromatography confirmed tha...

journal_title：Biochemical and biophysical research communications

authors： Ikegawa R,Matsumura Y,Tsukahara Y,Takaoka M,Morimoto S

更新日期：1990-09-14 00:00:00

abstract：:The isolation and sequence analysis of the gene encoding the bovine atrial natriuretic peptide (ANP) precursor is described. The bovine-ANP coding sequences are located on three exons which are interrupted by two intervening sequences. Comparison of the bovine, human, rat and mouse ANP gene sequences reveals a common ...

journal_title：Biochemical and biophysical research communications

authors： Vlasuk GP,Miller J,Bencen GH,Lewicki JA

更新日期：1986-04-14 00:00:00

abstract：:GTP cyclohydrolase I (GTPCH) is the first and rate-limiting enzyme for the synthesis of tetrahydrobiopterin (BH4), a cofactor of nitric oxide synthase (NOS). As the induction of NO synthesis by immunostimulants in vascular smooth muscle (VSM) cells requires de novo synthesis of BH4, we investigated whether immunostimu...

journal_title：Biochemical and biophysical research communications

authors： Hattori Y,Gross SS

更新日期：1993-08-31 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) expression is increased by hypertonicity. Therefore we hypothesized that hypertonicity increased PGE(2) can modulate the sodium transporters (Na(+)/K(+)-ATPase: NKA, epithelial sodium channel: ENaC, and sodium hydrogen exchanger: NHE) in M1 cortical collecting duct (CCD) cells. We demonstrated...

journal_title：Biochemical and biophysical research communications

authors： Nasrallah R,Paris G,Hébert RL

更新日期：2012-02-10 00:00:00

abstract：:The crenarchaeon Sulfolobus solfataricus contains three active origins of replication and three eukaryote-like Cdc6/Orc1 proteins known as SsoCdc6 proteins. It has the potential to become a powerful model system in understanding the central mechanism of the eukaryotic DNA replication. In this research, we designed a g...

journal_title：Biochemical and biophysical research communications

authors： He ZG,Feng Y,Jiang PX,Wang J

更新日期：2008-02-22 00:00:00

abstract：:Various subclasses of messenger ribonucleoprotein particles were prepared from free cytoplasmic and polysome fractions of rat liver on the basis of the homopolymeric content of the constituent RNA's. Two major proteins were evident in the free cytoplasmic preparations: the poly(A)-binding protein was the major constit...

journal_title：Biochemical and biophysical research communications

authors： Ford G,Nichols JL

更新日期：1984-05-16 00:00:00

abstract：:Calumenin is a multiple EF-hand Ca2+-binding protein located in endo/sarcoplasmic reticulum of mammalian tissues. In the present study, we cloned two rabbit calumenin isoforms (rabbit calumenin-1 and -2, GenBank Accession Nos. SY225335 and AY225336, respectively) by RT-PCR. Both isoforms contain a 19 aa N-terminal sig...

journal_title：Biochemical and biophysical research communications

authors： Jung DH,Mo SH,Kim DH

更新日期：2006-04-28 00:00:00

abstract：:Global rise in obesity at early age due to overconsumption of energy-dense food is the major health problem which increases the exposure to obesity over longer duration. Recently we reported that the severity of ovarian dysfunction depends on the duration of obesity. In the present study, we examined the consequences ...

journal_title：Biochemical and biophysical research communications

authors： Kannan S,Bhaskaran RS

更新日期：2019-11-12 00:00:00

abstract：:Two-types of high molecular mass proteases have been purified from sea urchin sperm using DEAE-Sephacel, hydroxylapatite and Superdex 200 column chromatography. Both proteases showed similar hydrolyzing activities toward synthetic peptides, but they differed in the molecular mass and peptide composition. One was proba...

journal_title：Biochemical and biophysical research communications

authors： Inaba K,Akazome Y,Morisawa M

更新日期：1992-01-31 00:00:00

abstract：:Dysregulation of microRNAs has been demonstrated to be involved in a variety of biological events related to cancer, including proliferation, metastasis, angiogenesis and immune escape. MiR-616-3p is located on the chromosome region 12q13.3, however, its potential role and clinical implications in gastric cancer remai...

journal_title：Biochemical and biophysical research communications

authors： Wu ZH,Lin C,Liu CC,Jiang WW,Huang MZ,Liu X,Guo WJ

更新日期：2018-07-02 00:00:00

abstract：:Parathyroid hormone (PTH) has a central role in the regulation of serum calcium and phosphate, while parathyroid hormone-related peptide (PTHrP) has important developmental roles. Both peptides signal through the same receptor, the PTH/PTHrP receptor (a class B G-protein-coupled receptor). The different biological eff...

journal_title：Biochemical and biophysical research communications

authors： Gensure RC,Gardella TJ,Jüppner H

更新日期：2005-03-18 00:00:00

abstract：:Leishmania donovani is an obligate intracellular parasite that infects macrophages of the vertebrate host resulting in visceral leishmaniasis in humans, a major public health problem worldwide. The molecular mechanisms involved in internalization of Leishmania are still poorly characterized. We report here that choles...

journal_title：Biochemical and biophysical research communications

authors： Tewary P,Veena K,Pucadyil TJ,Chattopadhyay A,Madhubala R

更新日期：2006-01-13 00:00:00

abstract：:Surfactant convertase is required for conversion of heavy density (H) natural surfactant to light density (L) subtype during cycling in vitro, a technique that reproduces surfactant metabolism. To study mechanisms of H to L conversion, we prepared liposomes of dipalmitoylphosphatidylcholine (DPPC) and phosphatidylglyc...

journal_title：Biochemical and biophysical research communications

authors： Dhand R,Sharma VK,Teng AL,Krishnasamy S,Gross NJ

更新日期：1998-03-27 00:00:00

abstract：:MS-209 is a novel quinoline derivative reversing P-glycoprotein-mediated multidrug resistance (MDR). We investigated the interaction between MS-209 and multidrug resistance protein (MRP) in MRP-overexpressing human gastric cancer cells. We measured [3H]leukotriene C4 uptake into the membrane vesicles of the cells and ...

journal_title：Biochemical and biophysical research communications

authors： Nakamura T,Oka M,Aizawa K,Soda H,Fukuda M,Terashi K,Ikeda K,Mizuta Y,Noguchi Y,Kimura Y,Tsuruo T,Kohno S

更新日期：1999-02-24 00:00:00

abstract：:The present study reports the presence of progesterone, testosterone and 17 beta-estradiol and their corresponding binding proteins in the reproductive system of Octopus vulgaris Lam (phylum Mollusca, subphylum Cephalopoda). These sex hormones occur in testis, vas deferens, seminal vesicle, prostate and Needham's sac....

journal_title：Biochemical and biophysical research communications

authors： D'Aniello A,Di Cosmo A,Di Cristo C,Assisi L,Botte V,Di Fiore MM

更新日期：1996-10-23 00:00:00

abstract：:Gene expression is the typical biological end point of interest following transfection. However, transcription may not accurately assess DNA uptake, or the ability of transfected DNA to be acted on by other enzymatic pathways. We have compared DNA uptake to gene expression and the unrelated enzymatic process of DNA do...

journal_title：Biochemical and biophysical research communications

authors： Pastwa E,Lubner EM,Mezhevaya K,Neumann RD,Winters TA

更新日期：2003-06-27 00:00:00

abstract：:A guinea pig adrenal hydroxysteroid sulfotransferase (gpHST2) has been cloned that is distinct from guinea pig hydroxysteroid sulfotransferase that stereoselectively acts on 3 alpha-hydroxylated neutral steroids (gp3 alpha HST, redesignated gpHST1). The deduced amino acid sequences for gpHST1 and gpHST2 are 86% identi...

journal_title：Biochemical and biophysical research communications

authors： Luu NX,Driscoll WJ,Martin BM,Strott CA

更新日期：1995-12-26 00:00:00

abstract：:A procedure is described for preparation of homogeneous inositol monophosphate phosphatase (EC 3.1.3.25) from beef brain in less than 2 days with an overall recovery of 15-25%. This enzyme, an essential part of the inositol phospholipid cycle in brain, is a proposed site of action of lithium ions in manic-depressive d...

journal_title：Biochemical and biophysical research communications

authors： Meek JL,Rice TJ,Anton E

更新日期：1988-10-14 00:00:00

abstract：:Telomeres, specialized domains assembled at the ends of linear chromosomes, are essential for genomic stability in eukaryotes. The formation and maintenance of telomeres are governed by numerous factors such as telomeric repeats, telomere-binding proteins, heterochromatin proteins, and telomerase. Here, we report Sde2...

journal_title：Biochemical and biophysical research communications

authors： Sugioka-Sugiyama R,Sugiyama T

更新日期：2011-03-18 00:00:00

abstract：:Hippocampal slices offer an excellent experimental system for the study of activity-induced changes in the postsynaptic density (PSD). While studies have documented electrophysiological and structural changes at synapses in response to precise manipulations of hippocampal slices, parallel biochemical and proteomic ana...

journal_title：Biochemical and biophysical research communications

authors： Dosemeci A,Tao-Cheng JH,Vinade L,Jaffe H

更新日期：2006-01-13 00:00:00

abstract：PURPOSE:Recently, the newly identified embryonic stem cell marker, Zinc finger and SCAN domain containing 4 gene (ZSCAN4), which plays a key role in genomic stability by regulating telomere elongation, was shown to co-localize with TRF1 foci. This suggests that the interaction of ZSCAN4 with TRF1 functions in regulatio...

journal_title：Biochemical and biophysical research communications

authors： Lee K,Gollahon LS

更新日期：2015-10-30 00:00:00

abstract：:Cellular uptake of succinylated catalase (Suc-CAT; Mw 227 kDa), bovine serum albumin (Suc-BSA; Mw 70 kDa), superoxide dismutase (Suc-SOD; Mw 34 kDa) and soybean trypsin inhibitor (Suc-STI; Mw 21 kDa) was studied using primary cultures of bovine brain microvessel endothelial cells (BMECs) developed as an in vitro model...

journal_title：Biochemical and biophysical research communications

authors： Tokuda H,Masuda S,Takakura Y,Sezaki H,Hashida M

更新日期：1993-10-15 00:00:00

abstract：:Autophagy is a bulk degradation process for subcellular proteins and organelles to manage cell starvation. Autophagy is associated with the formation of autophagosomes and further functions as a defense mechanism against infection by various pathogens. Human papillomavirus (HPV) infection induces an autophagy response...

journal_title：Biochemical and biophysical research communications

authors： Ishii Y

更新日期：2013-04-19 00:00:00