Abstract:
:Regional cerebral blood flow was studied in 17 bipolar I depressed patients (DSM-IV criteria) with single photon emission computed tomography (SPECT). Visual analysis of images revealed no abnormality in eight patients and abnormal findings in nine patients. In the nine patients with abnormal findings, all showed regional decreases of the uptake of (99m)Tc-D,L-hexamethylpropylene amine oxime (HMPAO, four in the frontal region, two in the basal ganglia, and three in both the frontal region and the basal ganglia). The patients with visible SPECT abnormalities had significantly higher scores on the Hamilton Rating Scale for Depression (HDRS).
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Benabarre A,Vieta E,Martín F,Lomeña F,Martínez-Aràn A,Colom F,Corbella B,Gastó C,Valdés Mdoi
10.1016/j.pscychresns.2003.11.003subject
Has Abstractpub_date
2004-12-30 00:00:00pages
285-9issue
3eissn
0165-1781issn
1872-7123pii
S0925-4927(04)00106-4journal_volume
132pub_type
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