Abstract:
:Increasing intravenous doses of naloxone (0.3 mg/kg, 1 mg/kg, and 2 mg/kg) were administered to normal subjects. Naloxone at 2 mg/kg, but not at lower doses, impaired aspects of memory as measured by a verbal learning task which assessed the direct free recall and recognition of presented versus non-presented words of a single category (effortful processing) and the monitoring of the frequency of such presentations (automatic processing). At the same time "working" memory was left unaffected. The results suggest a role for the opioid system in some memory processes in man.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Cohen RM,Cohen MR,Weingartner H,Pickar D,Murphy DLdoi
10.1016/0165-1781(83)90100-2subject
Has Abstractpub_date
1983-02-01 00:00:00pages
127-36issue
2eissn
0165-1781issn
1872-7123pii
0165-1781(83)90100-2journal_volume
8pub_type
杂志文章abstract::Few studies have examined risk factors associated with suicidal ideation and attempts among younger adolescents compared to their high-school aged counterparts. To gain a better understanding of unique risk factors associated with suicidal ideation and attempts among middle-school aged students, the current study empl...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112773
更新日期:2020-02-01 00:00:00
abstract::Disruptive behavior disorders (DBD) are among the most commonly diagnosed mental disorders in children and adolescents. Some important characteristics of DBD vary based on the presence or absence of comorbid attention-deficit/hyperactivity disorder (ADHD), which may affect the understanding of and treatment decision-m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2012.01.005
更新日期:2012-06-30 00:00:00
abstract::In an attempt to assess the influence of standardized diagnostic interviews on psychological distress in research volunteers, the Visual Analogue Scale (VAS) was used to measure anxiety and depression during the Structured Clinical Interview for DSM-III-R, Non-patient version (SCID). Subjects were 50 adults with conce...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02802-1
更新日期:1996-01-31 00:00:00
abstract::This study tested the hypothesis that adverse events are associated with increased risk of onset of anxiety disorders. Data from Waves 1 (N = 43,093; 2001-2002) and 2 (N = 34,653; 2004-2005) of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC) were used to assess whether adverse events at ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.11.027
更新日期:2018-01-01 00:00:00
abstract::Although deep grey matter (GM) involvement in multiple sclerosis (MS) is well documented, in-vivo multi-parameter magnetic resonance imaging (MRI) studies and association with detailed cognitive measures are limited. We investigated volumetric, diffusion and perfusion metrics in thalamus, hippocampus, putamen, caudate...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.10.004
更新日期:2015-12-30 00:00:00
abstract::Similar to members of the public, people with mental illness may exhibit general negative automatic prejudice against their own group. However, it is unclear whether more specific negative stereotypes are automatically activated among diagnosed individuals and how such automatic stereotyping may be related to self-rep...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.08.024
更新日期:2011-03-30 00:00:00
abstract::Age disorientation was studied in 45 geriatric patients with chronic mood disorders. In a yearly assessment of cognitive functions, subjects were questioned about their age, year of birth, and the current year. Patients who misstated their age by > or = 5 years were considered age disoriented. Among the 45 patients, a...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02853-6
更新日期:1996-02-28 00:00:00
abstract::Cannabis is widely used in adolescence; however, the effects of cannabis on the developing brain remain unclear. Cannabis might be expected to have increased effects upon brain development and cognition during adolescence. There is extensive re-organisation of grey (GM) and white matter (WM) at this time, while the en...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.pscychresns.2013.07.012
更新日期:2013-12-30 00:00:00
abstract::Persons with schizophrenia and schizoaffective disorder exhibit deficits in both visual processing and neuropsychological tasks. Little is known, however, about whether these deficits are related to one another. We administered psychophysical tests of visual discrimination and recognition, and neuropsychological tests...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00139-7
更新日期:2002-08-30 00:00:00
abstract::The major aims of this study were to examine how, if at all, having higher levels of PTSD would be associated with performance on a facial affect recognition task in which facial expressions of emotion are superimposed on emotionally valenced, non-face images. College students with trauma histories (N = 90) completed ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.055
更新日期:2018-07-01 00:00:00
abstract::Phantom studies and cerebral blood flow (CBF) measurements in 11 normal subjects at rest were performed by single photon emission tomography (SPECT) with Xe-133 (16 mm full-width at half-maximum [FWHM] collimation) and Xe-127 (16 mm, 12 mm, and 9 mm FWHM collimation). The phantom results clearly illustrated the feasib...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Social functioning is an important component of mental disorders for assessment and treatment. There is no recognised self-report instrument to measure social functioning across disorders where social impairment is significant. The Social Functioning Scale (SFS) has, however, been used to assess social functioning in ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.03.037
更新日期:2019-06-01 00:00:00
abstract::Preliminary data are presented on levels of plasma cortisol, dopamine (DA), epinephrine (EPI), and norepinephrine (NE) before and after dexamethasone in 22 depressed patients (of whom 4 were psychotic). Platelet monoamine oxidase (MAO) activity, determined in 19 of the depressed patients, was significantly higher in t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90007-2
更新日期:1987-02-01 00:00:00
abstract::This study examines sexual behavior, serotonin turnover in the central nervous system, and testosterone in free-ranging non-human primates. Study subjects were 33 young adult male rhesus macaques (Macaca mulatta) living in naturalistic social groups on a 475-acre South Carolina barrier island. Blood and cerebrospinal ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(97)00084-x
更新日期:1997-09-19 00:00:00
abstract::The phenotypic heterogeneity of Autism Spectrum Disorders (ASD) presents particular research challenges in the assessment of symptom severity, while the standardized Autism Diagnostic Observation Schedule (ADOS) scores present a severity metric, namely calibrated severity scores (CSS) that are relatively impervious to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.12.084
更新日期:2018-03-01 00:00:00
abstract::Genetic and environmental architecture of psychotic and obsessive symptoms are not completely elucidated. This study estimated for these symptoms (i) the genetic and environmental components, (ii) the within-individual association, and (iii) the extent to which this association originates from common genetic and envir...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.12.002
更新日期:2011-07-30 00:00:00
abstract::Social anhedonia is a promising indicator for the vulnerability towards developing schizophrenia-spectrum disorders and is an important determinant of the social impairment associated with these disorders. It is unknown if social anhedonia is associated with true deficits in experiential reactions or if lower social f...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.07.050
更新日期:2012-12-30 00:00:00
abstract::Adult attention deficit hyperactivity disorder (ADHD) is frequently associated with borderline personality disorder (BPD). As both disorders share some core clinical features they are sometimes difficult to distinguish from one another. The present work aimed to investigate differences in the expression of impulsivity...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.03.006
更新日期:2014-06-30 00:00:00
abstract::Over the past decade there has been consistent criticism of the diagnostic criteria of posttraumatic stress disorder (PTSD) because of its high comorbidity with other mental disorders. Part of the problem surrounding PTSD may be related to the heterogeneity of its symptoms. In fact, recent research has identified a su...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2011.10.022
更新日期:2012-04-30 00:00:00
abstract::The aim of this study was to examine insomnia symptoms, behavioral problems, and suicidality among adolescents of insomniac parents (IP) and non-insomniac parents (NIP). A family survey of sleep and health was conducted among 1090 adolescents and their parents in Jinan, China. Adolescents completed a sleep and health ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.05.023
更新日期:2015-08-30 00:00:00
abstract::The experience of maternal distress in pregnancy is often linked with poorer obstetric outcomes for women as well as adverse outcomes for offspring. Alterations in placental glucocorticoid signalling and subsequent increased fetal exposure to cortisol have been suggested to underlie this relationship. In the current s...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.05.013
更新日期:2017-09-01 00:00:00
abstract::This study was aimed to explore clinical differences between women and men with schizophrenia (SZ) in Latin-America. It was conducted in public mental health centers in Bolivia, Peru and Chile. Two hundred forty-seven SZ patients participated in the study, 83 (33.6%) were women and 115 (46.6%) were Aymara. Compared to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.05.032
更新日期:2018-08-01 00:00:00
abstract::Persistent infection with Herpes Simplex viruses (HSV) and other brain infections is consistently associated with cognitive impairment. These infections can also affect sleep. Thus, sleep abnormalities could explain the cognitive dysfunction. We investigated the association between sleep variables and persistent HSV-1...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112502
更新日期:2019-10-01 00:00:00
abstract::Physical restraint (PR) for patients is an ongoing controversial topic in psychiatry. This study examined the percentage of PR and its associations with clinical characteristics and the implementation of the National Mental Health Law (NMHL) in China. The study consecutively assessed a sample of 1364 psychiatric inpat...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.04.101
更新日期:2016-07-30 00:00:00
abstract::Internet addiction became a major mental health problem in college student. Our objective was to examine the relationship between psychological inflexibility and experiential avoidance (PIEA) and Internet addiction (IA) and the mediating effects of mental health problem indicators. 500 college students (238 men and 26...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.07.021
更新日期:2017-11-01 00:00:00
abstract::This report presents the simultaneous pattern of cerebral blood flow and cerebral glucose metabolism in two patients with a major depressive disorder who were undergoing continuation ECT. The regional cerebral blood flow and regional cerebral metabolic rate of these patients were imaged using double isotope 18F-FDG an...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(03)00077-5
更新日期:2003-11-30 00:00:00
abstract::Brain morphology was assessed qualitatively in CT scans of 21 patients with panic disorder and 21 normal control subjects. Patients showed significant bilateral enlargement of frontal cerebrospinal fluid (CSF) spaces. These findings suggest that alterations in brain morphology are involved in the etiology of panic dis...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(97)00065-6
更新日期:1997-12-30 00:00:00
abstract::Controversy exists regarding the association of age with postdexamethasone serum cortisol levels. We evaluated this relationship in 95 patients with major depressive disorder and 49 healthy controls. Age and 8 a.m. postdexamethasone cortisol levels were not correlated among the healthy controls, but were positively as...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90036-2
更新日期:1984-11-01 00:00:00
abstract::This study analyzed interrelationships among plasma level of haloperidol (HAL), electroencephalographic (EEG) changes, and clinical response in 37 acutely exacerbated schizophrenic patients after a 6-week period of treatment. Two hypotheses were tested: (1) EEG theta response to HAL depends on levels of HAL in plasma,...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(92)90077-g
更新日期:1992-05-01 00:00:00
abstract::Diminished neural responses to punitive stimulus related to high level of pain avoidance may be biomarkers in distinguishing patients with history of suicide attempts from those without such histories. Outpatients with Major Depression Disorder (MDD, n=44) and healthy controls (HCs, n=28) were administered the Beck De...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113507
更新日期:2020-12-01 00:00:00