Evidence for brain-derived neurotrophic factor-like neuropeptide in brain of the silk moth Bombyx mori during postembryonic periods.

abstract：:This study determined the long-term influence of prenatal nicotine exposure (PN) on blood pressure and vascular functions in the aged offspring rats. PN did not affect body weight and plasma adrenocorticotropic hormone level; however, it significantly reduced plasma angiotensin I and angiotensin II in both sexes. Syst...

journal_title：Peptides

authors： Tao H,Rui C,Zheng J,Tang J,Wu L,Shi A,Chen N,He R,Wu C,Li J,Yin X,Zhang P,Zhu Z,Tao J,Xiao J,Mao C,Xu Z

更新日期：2013-06-01 00:00:00

abstract：:alpha-MSH stimulates steroid secretion by rat adrenal zona glomerulosa cells and tissues but not fasciculata/reticularis cells when added to in vitro incubations. With glomerulosa cells from control animals on a normal sodium intake, production of corticosterone was significantly stimulated at an alpha-MSH concentrati...

journal_title：Peptides

authors： Vinson GP,Whitehouse BJ,Thody AJ

更新日期：1981-07-01 00:00:00

abstract：:The functions of leptin receptors (LRs) are cell-type specific. At the blood-brain barrier, LRs mediate leptin transport that is essential for its CNS actions, and both endothelial and astrocytic LRs may be involved. To test this, we generated endothelia specific LR knockout (ELKO) and astrocyte specific LR knockout (...

journal_title：Peptides

authors： Hsuchou H,Kastin AJ,Tu H,Markadakis EN,Stone KP,Wang Y,Heymsfield SB,Chua SS Jr,Obici S,Magrisso IJ,Pan W

更新日期：2011-07-01 00:00:00

abstract：:In this study, antimicrobial peptide S-thanatin (Ts) was chemically synthesized and linked to keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA) by carbodiimide reagent. Rabbits were immunized with Ts-KLH and polyclonal antibody against Ts was purified by fractional precipitation of ammonium sulfate, coupl...

journal_title：Peptides

authors： Wu G,Wang S,Wang X,Li X,Deng X,Shen Z,Xi T

更新日期：2011-07-01 00:00:00

abstract：:The striatum is richly innervated by both enkephalinergic and dopaminergic neurons, providing an anatomic framework from which intimate functional interrelationships between these neuronal systems may be postulated. Accordingly, many functional processes within dopamine neurons have been shown to be modulated by opioi...

journal_title：Peptides

authors： George SR,Kertesz M

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Visfatin is a novel adipokine and proinflammatory cytokine which is implicated in breast cancer progression. The exact proliferative and anti-apoptotic mechanisms of visfatin are still under debate. In this study, the effect of extracellular visfatin on proliferation and apoptosis of breast cancer cells were...

journal_title：Peptides

authors： Gholinejad Z,Kheiripour N,Nourbakhsh M,Ilbeigi D,Behroozfar K,Hesari Z,Golestani A,Shabani M,Einollahi N

更新日期：2017-06-01 00:00:00

abstract：:Copeptin can reflect individual's stress state and are correlated with poor outcome of critical illness. The occurrence of postoperative delirium (POD) and cognitive dysfunction (POCD) is associated with worse outcome after coronary artery bypass graft (CABG) surgery. The present study aimed to investigate the ability...

journal_title：Peptides

authors： Dong S,Li CL,Liang WD,Chen MH,Bi YT,Li XW

更新日期：2014-09-01 00:00:00

abstract：:Both diapause hormone (DH) and ecdysone (E) are capable of terminating pupal diapause in members of the Helicoverpa/Heliothis complex. In this study we examine how the transcript encoding prothoracicotropic hormone (PTTH), the neuropeptide that stimulates the prothoracic gland to produce E, and the transcript encoding...

journal_title：Peptides

authors： Zhang Q,Denlinger DL

更新日期：2012-03-01 00:00:00

abstract：:The aim of this study was to investigate peripheral and central roles of corticotropin-releasing factor (CRF) in endocrinological and behavioral changes. Plasma adrenocorticotropin (ACTH) concentration was measured as an activity of hypothalamic-pituitary-adrenal (HPA) axis. As behavioral changes, locomotion and anxie...

journal_title：Peptides

authors： Tanaka M,Tomimatsu Y,Sakimura K,Ootani Y,Sako Y,Kojima T,Aso K,Yano T,Hirai K

更新日期：2017-09-01 00:00:00

abstract：:beta-Lactotensin (beta-LT) is a bioactive peptide derived from bovine milk beta-lactoglobulin and is a natural ligand for neurotensin receptors. We examined the effect of beta-LT on restraint stress and fear memory in mice. Mice subjected to acute restraint stress exhibited a decreased number of head-dips and increase...

journal_title：Peptides

authors： Yamauchi R,Wada E,Yamada D,Yoshikawa M,Wada K

更新日期：2006-12-01 00:00:00

abstract：:Peptide YY (PYY)(3-36), a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion. Based on this anti-secretory effect, NPY Y2 receptor agonists may be useful as novel anti-diarrheal agents, but anti-diarrheal efficacy has yet to be determined. We therefore examined the anti-diarrheal...

journal_title：Peptides

authors： Moriya R,Shirakura T,Hirose H,Kanno T,Suzuki J,Kanatani A

更新日期：2010-04-01 00:00:00

abstract：:To determine whether a sex difference exists in the biosynthetic capacity of vasopressingergic (AVP) neurons in the bed nucleus of the stria terminalis (BNST), we have used in situ hybridization and quantitative autoradiography to measure propressophysin messenger RNA levels in these cells from adult male and female r...

journal_title：Peptides

authors： Miller MA,Vician L,Clifton DK,Dorsa DM

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Since short bowel syndrome (SBS) patients face life-threatening conditions, the development of therapeutic strategies to induce intestinal adaptation has been investigated. Ghrelin, a ligand of growth hormone (GH) secretagogue-receptor that stimulates the release of GH and insulin like growth factor-1 (IGF-1...

journal_title：Peptides

authors： Onishi S,Kaji T,Yamada W,Nakame K,Machigashira S,Kawano M,Yano K,Harumatsu T,Yamada K,Masuya R,Kawano T,Mukai M,Hamada T,Souda M,Yoshioka T,Tanimoto A,Ieiri S

更新日期：2018-08-01 00:00:00

abstract：:Intestinal levels of immunoreactive neurotensin (iNT) and neuromedin N (iNMN), as well as mRNA for the NT/NMN precursor, were elevated during the suckling period in rats. While transient expression of NT/NMN was observed at 1-5 days of age in the proximal small intestine and colon, NT/NMN levels in the ileum increased...

journal_title：Peptides

authors： Muraki K,Mitra SP,Dobner PR,Carraway RE

更新日期：1993-11-01 00:00:00

abstract：:The pentapeptide pGlu-Asn-Cyt-Pro-Arg [AVP(4-8), termed ZNC(C)PR in this article] has been found as a metabolite of arginine-vasopressin (AVP) in rat brain and has been shown to have potent memory-enhancing activity and to yield a series of biochemical events in brain tissues. [35S]ZNC(C)PR was chemically synthesized ...

journal_title：Peptides

authors： Du YC,Wu JH,Jiang XM,Gu YJ

更新日期：1994-01-01 00:00:00

abstract：:Angiotensin II (Ang II) uptake and transport across monolayers of bovine brain microvessel endothelial cells (BMECs) was demonstrated. Ang II transport was linear up to 2 h, saturable with a K(m) of 1.7 nM, and tended to be polarized with the apical-to-basolateral transport being greater. [3H]Ang II transport was foun...

journal_title：Peptides

authors： Rose JM,Audus KL

更新日期：1998-01-01 00:00:00

abstract：:The insect kinin neuropeptides have been implicated in the regulation of water balance, digestive organ contraction, and energy mobilization in a number of insect species. A previous solution conformation study of an active, restricted-conformation cyclic analog, identified two possible turn conformations as the likel...

journal_title：Peptides

authors： Nachman RJ,Zabrocki J,Olczak J,Williams HJ,Moyna G,Ian Scott A,Coast GM

更新日期：2002-04-01 00:00:00

abstract：:Binding of [125I]PACAP-38 to rat liver membranes was investigated. It was rapid at 37 degrees C, reversible, and saturable, and it was time, concentration, and temperature dependent. Scatchard plots showed that [125I]PACAP-38 bound to single noninteracting site(s), and [125I]VIP bound to high- and low-affinity binding...

journal_title：Peptides

authors： Bitar KG,Somogyvari-Vigh A,Coy DH

更新日期：1994-01-01 00:00:00

abstract：:Mussels have diverse groups of cysteine rich, cationic antimicrobial peptides (AMPs) (defensins, mytilins, myticins, and mytimycin) that constitute an important component of their innate immune defence. Despite the identification and characterization of these AMPs in mussels, the underlying genetic mechanisms that mai...

journal_title：Peptides

authors： Padhi A,Verghese B

更新日期：2008-07-01 00:00:00

abstract：:More than 40 peptides belonging to the -Y/FXFGL-NH(2) allatostatin superfamily have been isolated and identified from the central nervous system (CNS) of the tiger prawn, Penaeus monodon (Crustacea: Penaeidea). The peptides can be arranged in seven sub-groups according to the variable post-tyrosyl residue represented ...

journal_title：Peptides

authors： Duve H,Johnsen AH,Scott AG,Thorpe A

更新日期：2002-06-01 00:00:00

abstract：:Tardive dyskinesia, a clinical syndrome, is one of the major side effects of protracted treatment with neuroleptics in schizophrenic patients. Functional supersensitivity of striatal dopamine receptors is believed to contribute to the pathogenesis of schizophrenia and tardive dyskinesia. In a rodent model of neurolept...

journal_title：Peptides

authors： Rajakumar G,Naas F,Johnson RL,Chiu S,Yu KL,Mishra RK

更新日期：1987-09-01 00:00:00

abstract：:Substance P (SP) has been implicated in the pathophysiology of ulcerative colitis (UC) and it has been suggested that blocking of its effect would be advantageous in this disease. Eosinophils have also been implicated in the pathophysiology of UC. In the present study, specimens from the sigmoid colon of UC patients w...

journal_title：Peptides

authors： Jönsson M,Norrgård O,Forsgren S

更新日期：2005-05-01 00:00:00

abstract：:Enzymatic cleavage of endogenous peptides is a commonly used principle to initiate, modulate and terminate action for instance among cytokines and peptide hormones. The incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), and the related hormone glucagon-like pepti...

journal_title：Peptides

authors： Gabe MBN,van der Velden WJC,Smit FX,Gasbjerg LS,Rosenkilde MM

更新日期：2020-03-01 00:00:00

abstract：:The effects of atrial natriuretic factor (ANF) on [3H]norepinephrine ([3H]NE) release evoked by a sodium-free medium (SFM) were studied. Experiments were performed in rat adrenal medulla slices incubated in vitro. Results showed that [3H]NE release evoked by the omission of Na+ was decreased by 10 nM ANF. In addition,...

journal_title：Peptides

authors： Vatta MS,Papouchado ML,Bianciotti LG,Fernandez BE

更新日期：1994-01-01 00:00:00

abstract：:Intracerebroventricular (ICV) bombesin increases grooming and decreases food intake in rats. We examined tolerance to these effects by administering a daily injection of either saline or 25 ng bombesin to rats for 8 days via lateral ventricular cannulas. Food intake and grooming were monitored. After 8 days bombesin n...

journal_title：Peptides

authors： Corwin RL,Corp ES,Gibbs J,Smith GP

更新日期：1992-11-01 00:00:00

abstract：:A new CCK8 related peptide, Boc[Nle28,Nle31]CCK27-33 (Boc[diNle]CCK7) was synthesized and tested for cholecystokinic activity, at both the peripheral and the central level. This analogue, protected against both chemical oxidation and enzymatic degradation by aminopeptidases, was shown to be equipotent to CCK8 in relea...

journal_title：Peptides

authors： Ruiz-Gayo M,Daugé V,Menant I,Bégué D,Gacel G,Roques BP

更新日期：1985-05-01 00:00:00

abstract：:The presence of immunoreactive porcine brain natriuretic peptide in rat tissues was studied with a specific radioimmunoassay for porcine brain natriuretic peptide-26. The cross-reactivity of the antiserum used was less than 0.001% with rat atrial natriuretic peptide, rat brain natriuretic peptide-32 and rat brain natr...

journal_title：Peptides

authors： Sone M,Totsune K,Takahashi K,Ohneda M,Itoi K,Murakami O,Yoshinaga K,Mouri T

更新日期：1991-11-01 00:00:00

abstract：:Ureases (EC 3.5.1.5) are metalloenzymes that hydrolyze urea into ammonia and CO(2). These proteins have insecticidal and fungicidal effects not related to their enzymatic activity. The insecticidal activity of urease is mostly dependent on the release of internal peptides after hydrolysis by insect digestive cathepsin...

journal_title：Peptides

authors： Postal M,Martinelli AH,Becker-Ritt AB,Ligabue-Braun R,Demartini DR,Ribeiro SF,Pasquali G,Gomes VM,Carlini CR

更新日期：2012-11-01 00:00:00

abstract：:The term "oxidative stress" indicates a set of chemical reactions unleashed by a disparate number of events inducing DNA damage, lipid peroxidation, protein modification and other effects, which are responsible of altering the physiological status of cells or tissues. Excessive Reactive Oxygen Species (ROS) levels may...

journal_title：Peptides

authors： Sandomenico A,Severino V,Apone F,De Lucia A,Caporale A,Doti N,Russo A,Russo R,Rega C,Del Giacco T,Falcigno L,Ruvo M,Chambery A

更新日期：2017-03-01 00:00:00

abstract：:The goal of our study was to explore the effect of social isolation stress of varying durations on the plasma oxytocin (OT), messenger ribonucleic acid (mRNA) for oxytocin receptor (OTR), plasma arginine vasopressin (AVP) and mRNA for V1a receptor of AVP (V1aR) expression in the hypothalamus and heart of socially mono...

journal_title：Peptides

authors： Pournajafi-Nazarloo H,Kenkel W,Mohsenpour SR,Sanzenbacher L,Saadat H,Partoo L,Yee J,Azizi F,Carter CS

更新日期：2013-05-01 00:00:00