Abstract:
:To determine whether a sex difference exists in the biosynthetic capacity of vasopressingergic (AVP) neurons in the bed nucleus of the stria terminalis (BNST), we have used in situ hybridization and quantitative autoradiography to measure propressophysin messenger RNA levels in these cells from adult male and female rats. We have found that significantly more (p less than 0.01) neurons are labeled in male rats than in female rats and that these labeled cells averaged more grains/cell (p less than 0.05) in males than in females. Therefore, the sexual dimorphism of AVP pathways in the BNST and lateral septum recently shown by immunohistochemistry results from a sex difference in the biosynthetic capacity of these AVP neurons.
journal_name
Peptidesjournal_title
Peptidesauthors
Miller MA,Vician L,Clifton DK,Dorsa DMdoi
10.1016/0196-9781(89)90152-6subject
Has Abstractpub_date
1989-05-01 00:00:00pages
615-9issue
3eissn
0196-9781issn
1873-5169pii
0196-9781(89)90152-6journal_volume
10pub_type
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