Abstract：
:The inability to modulate processing time in conjunction with varying difficulty levels may be a core component of schizophrenia's cognitive deficit. In this study we used a parametric design to demonstrate this group's inability to increase and decrease response times in association with varying levels of task demand during auditory and visual recognition tasks. Unlike participants with schizophrenia, healthy volunteers responded to increasing levels of difficulty and high error by robustly increasing their average response times. In the group with schizophrenia, the greater the correlation between a subject's Response-Time and error rate the better was the subject in his/her overall discrimination accuracy. The higher their correlations the better they performed across all levels of difficulty in both modalities. The schizophrenia group's tendency to process high and low error conditions with similar behavioral resources may reflect a relatively static, non-dynamic cognitive repertoire.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Holcomb HH,Parwani A,McMahon RP,Medoff DR,Frey K,Lahti AC,Tamminga CAdoi
10.1016/j.psychres.2004.04.003subject
Has Abstractpub_date
2004-07-15 00:00:00pages
207-16issue
3eissn
0165-1781issn
1872-7123pii
S016517810400099Xjournal_volume
127pub_type
杂志文章abstract：:Patients with bipolar mania often require re-hospitalization, which can be a social-economic burden. This study aimed to investigate the factors affecting time to re-hospitalization for inpatients with acute bipolar mania. In this 6-year naturalistic study we reviewed the charts of inpatients with acute bipolar mania....
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