Abstract：
:Asymmetric cell divisions are central to the generation of cell-fate diversity because factors that are present in a mother cell and distributed unequally at cell division can generate distinct daughters. The process o f asymmetric cell division can be described as consisting of three steps: setting up an asymmetric cue in the mother cell, localizing factors with respect to this cue, and positioning the plane o f cell division so that localized factors are partitioned asymmetrically between daughters. This review describes how specialized cortical domains play a key role in each of these steps and discusses our current understanding of the molecular nature o f cortical domains and the mechanisms by which they may orchestrate asymmetric cell divisions.
journal_name
Trends Cell Bioljournal_title
Trends in cell biologyauthors
Gönczy P,Hyman AAdoi
10.1016/0962-8924(96)10035-0subject
Has Abstractpub_date
1996-10-01 00:00:00pages
382-7issue
10eissn
0962-8924issn
1879-3088pii
0962-8924(96)10035-0journal_volume
6pub_type
杂志文章abstract：:The glycoproteome, the ensemble of glycans and their carrier proteins, plays major roles in multicellular life by regulating cell interactions with their environment. How information is encoded into the glycome, in other words how glycosylation is modulated in response to signals, remains largely unclear. Glycosylatio...
journal_title：Trends in cell biology
pub_type： 杂志文章,评审
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abstract：:To battle adverse internal and external conditions and maintain homeostasis, diploid organisms employ various cellular processes, such as proliferation and apoptosis. In some tissues, an alternative mechanism, endoreplication, is employed toward similar goals. Endoreplication is an evolutionarily conserved cell cycle ...
journal_title：Trends in cell biology
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
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更新日期：1995-01-01 00:00:00
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
pub_type： 杂志文章
doi：10.1016/j.tcb.2020.12.007
更新日期：2020-12-29 00:00:00
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journal_title：Trends in cell biology
pub_type： 杂志文章
doi：10.1016/0962-8924(93)90136-o
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journal_title：Trends in cell biology
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更新日期：1994-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.tcb.2008.08.004
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journal_title：Trends in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.tcb.2003.12.003
更新日期：2004-02-01 00:00:00
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journal_title：Trends in cell biology
pub_type： 杂志文章
doi：10.1016/S0962-8924(97)01079-9
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
pub_type： 杂志文章
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journal_title：Trends in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.tcb.2014.08.009
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
pub_type： 杂志文章,评审
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更新日期：2014-07-01 00:00:00
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
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journal_title：Trends in cell biology
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更新日期：2019-11-01 00:00:00
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journal_title：Trends in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.tcb.2017.10.007
更新日期：2018-02-01 00:00:00
