Abstract：
:We assessed whether measles virus-specific antibody levels in the Dutch population as estimated by an enzyme-linked immunosorbent assay (ELISA) were comparable with estimates by virus neutralisation assay (NT), prompted by a relatively low ELISA seroprevalence in the 10-21-year-old group. We tested 791 sera from individuals aged 2-49 years both in ELISA and NT. Seroprevalence in the 10-21-year-old group was 93.4% (95% confidence interval (CI) 89.5-97.2%) in ELISA versus 97.2% (CI 94.7-99.6%) in NT. There was good agreement between NT and ELISA seroprevalences in the vaccinated 2-9-year-olds and the unvaccinated 22-49-year-olds.
journal_name
Vaccinejournal_title
Vaccineauthors
van den Hof S,van Gageldonk-Lafeber AB,van Binnendijk RS,van Gageldonk PG,Berbers GAdoi
10.1016/s0264-410x(03)00490-0subject
Has Abstractpub_date
2003-10-01 00:00:00pages
4210-4issue
27-30eissn
0264-410Xissn
1873-2518pii
S0264410X03004900journal_volume
21pub_type
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