Maternal immunization with inactivated influenza vaccine: rationale and experience.

abstract：:Vaccination with viral-based vaccines continues to hold promise for the prevention of malaria. Whilst antigen-specific T cell responses are considered a major aim of such an approach, a role for induced NK cells as anti-malarial effector cells, or in shaping T cell responses, has received less attention. In this study...

journal_title：Vaccine

authors： Berthoud TK,Fletcher H,Porter D,Thompson F,Hill AV,Todryk SM

更新日期：2009-12-10 00:00:00

abstract：:Seven volunteers involved in flavivirus studies have been immunized with commercial Japanese encephalitis and yellow fever vaccines JE-VAX and YF-VAX. Strong homologous and cross-reactive with West Nile virus (WNV) antibody responses with titers 1:1600 to 1:51200 were found in all donors. All donors developed high lev...

journal_title：Vaccine

authors： Yamshchikov G,Borisevich V,Kwok CW,Nistler R,Kohlmeier J,Seregin A,Chaporgina E,Benedict S,Yamshchikov V

更新日期：2005-09-15 00:00:00

abstract：:This study aimed to evaluate the durability of the immunogenicity of MVA85A beyond infancy. Participants in an immunogenicity study of MVA85A administered at age of 4 months had additional evaluation 14 months after initial vaccination for IFN-γ ELISPOT responses to Ag85A peptide and ESAT6/CFP-10 and tuberculin skin t...

journal_title：Vaccine

authors： Odutola AA,Owolabi OA,Owiafe PK,McShane H,Ota MO

更新日期：2012-08-17 00:00:00

abstract：:Little is known of men's knowledge of cervical cancer and its links with human papillomavirus (HPV), or of their attitudes and beliefs about HPV vaccination. This is despite men's sexual behaviour contributing to HPV transmission and their potential role in deciding whether their children are vaccinated against HPV. T...

journal_title：Vaccine

authors： Pitts M,Smith A,Croy S,Lyons A,Ryall R,Garland S,Wong ML,Hseon TE

更新日期：2009-05-14 00:00:00

abstract：:The recovery of wild type and attenuated human parainfluenza type 3 (PIV3) recombinant viruses has made possible a new strategy to rapidly generate a live-attenuated vaccine virus fof PIV1. We previously replaced the coding sequences for the hemagglutinin-neuraminidase (HN) and fusion (F) proteins of PIV3 with those o...

journal_title：Vaccine

authors： Tao T,Skiadopoulos MH,Durbin AP,Davoodi F,Collins PL,Murphy BR

更新日期：1999-03-05 00:00:00

abstract：:In 2013, avian H7N9 influenza viruses were detected infecting people in China resulting in high mortality. Influenza H7 vaccines that provide cross-protection against these new viruses are needed until specific H7N9 vaccines are ready to market. In this study, an available H7N3 cold-adapted, temperature sensitive, liv...

journal_title：Vaccine

authors： Carter DM,Bloom CE,Kirchenbaum GA,Tsvetnitsky V,Isakova-Sivak I,Rudenko L,Ross TM

更新日期：2015-01-01 00:00:00

abstract：:Amid provider reports of financial barriers as an impediment to adult immunization, this study explores the time and costs of vaccination in adult provider practices. Both a Vaccination Time-Motion Study and Vaccine Practice Management Survey were conducted (March - October 2017) in a convenience sample of 19 family m...

journal_title：Vaccine

authors： Shen A,Khavjou O,King G,Bates L,Zhou F,Leidner AJ,Yarnoff B

更新日期：2019-02-04 00:00:00

abstract：:Former investigations demonstrated that the envelope glycoprotein E2 could protect pigs from classical swine fever virus (CSFV). Based on these findings, we prepared synthetic peptide vaccine using E2 N-terminal antigenic units B/C and hoped to induce protective activity against lethal challenge of virulent CSFV strai...

journal_title：Vaccine

authors： Dong XN,Wei K,Liu ZQ,Chen YH

更新日期：2002-12-13 00:00:00

abstract：BACKGROUND:To block transmission of measles, the China Ministry of Health endorsed the "2006-2012 National Measles Elimination Action Plan (NMEAP)" on November 11, 2006, while no published studies used mathematical models to assess the impact of this action. Also, the problem of residuals autocorrelation due to auto-co...

journal_title：Vaccine

authors： Xu L,Chen J,Zhan Z,Chen T,Liu W,Qian J,Ou C

更新日期：2020-06-09 00:00:00

abstract：:This phase 1 clinical trial assessed the safety and immunogenicity of a native outer membrane vesicle (NOMV) vaccine prepared from a lpxL2(-) synX(-) mutant of strain 44/76 with opcA expression stabilized. Thirty-four volunteers were assigned to one of the three dose groups (25 mcg, 25 mcg with aluminum hydroxide adju...

journal_title：Vaccine

authors： Keiser PB,Gibbs BT,Coster TS,Moran EE,Stoddard MB,Labrie JE 3rd,Schmiel DH,Pinto V,Chen P,Zollinger WD

更新日期：2010-10-08 00:00:00

abstract：:Trehalose-6,6'-dimycolate (TDM) and its monosaccharide-type analogues were synthesized, and their lethal and adjuvant activities were examined in mice. All the monosaccharide-type analogues with a glucose or N-acetylglucosamine moiety were devoid of lethal toxicity to mice; in particular, D-GlcNAcM(1-deoxy) and D-GlcN...

journal_title：Vaccine

authors： Sakurai T,Saiki I,Ishida H,Takeda K,Azuma I

更新日期：1989-06-01 00:00:00

abstract：:The practicalities when applying the ICH GCPs (International Conference on Harmonization 1996 Good Clinical Practices [EU, MHLW, FDA. International Conference on Harmonization Guideline for Good Clinical Practice; 1997] in less developed countries (ldcs) are seldom discussed and we found no guidelines as how to "adapt...

journal_title：Vaccine

authors： Acosta CJ,Galindo CM,Ochiai RL,Danovaro-Holliday MC,Laure-Page A,Thiem VD,Jin Y,Khan MI,Sahito SM,Hamza HB,Park JK,Lee H,Bock H,Elyazeed RA,Albert MJ,Ascaso C,Robles TQ,Ali M,Ngai P,Puri MK,Koo YM,Agtini MD,So

更新日期：2007-04-12 00:00:00

abstract：:Despite of highly active antiretroviral therapy, the response to vaccines in HIV-infected children is poor and short-lived, probably due to a defect in cellular immune responses. We compared the cellular immune response (assessed in terms of IFN-γ production) to tetanus toxoid and to cytomegalovirus in a series of 13 ...

journal_title：Vaccine

authors： Alsina L,Noguera-Julian A,Fortuny C

更新日期：2013-05-07 00:00:00

abstract：:HIV vaccines of the first generation are, in contrast to most currently licensed vaccines, unlikely to provide sterilizing immunity against infection with HIV. However, they are expected to exert a beneficial effect on the maintenance of CD4 T-cell counts by reducing viral load. There is a recognized need for clarifyi...

journal_title：Vaccine

authors： Fruth U

更新日期：2009-03-23 00:00:00

abstract：:Dengue is a significant threat to public health worldwide. Currently, there are no licensed vaccines available for dengue. Takeda Vaccines Inc. is developing a live, attenuated tetravalent dengue vaccine candidate (TDV) that consists of an attenuated DENV-2 strain (TDV-2) and three chimeric viruses containing the prM ...

journal_title：Vaccine

authors： Osorio JE,Partidos CD,Wallace D,Stinchcomb DT

更新日期：2015-12-10 00:00:00

abstract：:The incidence of cervical cancer in Latin America and the Caribbean (LAC) is among the highest in the world. Because there are major demographic shifts happening in LAC countries (population growth, urbanization and ageing) cervical cancer incidence and mortality will likely continue to be a significant public health ...

journal_title：Vaccine

authors： Almonte M,Albero G,Molano M,Carcamo C,García PJ,Pérez G

更新日期：2008-08-19 00:00:00

abstract：:Human respiratory syncytial virus (RSV) is a leading cause of severe respiratory disease and hospitalizations in infants and young children. It also causes significant morbidity and mortality in elderly and immune compromised individuals. No licensed vaccine currently exists. Parainfluenza virus 5 (PIV5) is a paramyxo...

journal_title：Vaccine

authors： Phan SI,Chen Z,Xu P,Li Z,Gao X,Foster SL,Teng MN,Tripp RA,Sakamoto K,He B

更新日期：2014-05-23 00:00:00

abstract：:Salmonella enterica serovar Typhimurium is a versatile host organism for the generation of recombinant live vaccines for mucosal immunization. We investigated the performance of an intracellular-activated promoter for expression of heterologous antigens by Salmonella carrier strains. We observed that intracellular exp...

journal_title：Vaccine

authors： Husseiny MI,Hensel M

更新日期：2005-04-08 00:00:00

abstract：:Effects of cholera toxin B subunits supplemented with 0.1% cholera toxin (CTB*) on systemic IgE antibody responses to ovalbumin (OVA) were examined in BDFI (H-2b/d), Balb/c (H-2d) and C3H (H-2k) mice given OVA intragastrically or intranasally. Two successive doses of OVA intragastrically administered to Balb/c and C3H...

journal_title：Vaccine

authors： Tamura S,Shoji Y,Hasiguchi K,Aizawa C,Kurata T

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Although two antigenically distinct B strain lineages of influenza have co-circulated globally since the mid-1980s, trivalent influenza vaccines (TIVs) contain only one, resulting in frequent mismatches. This study examined the safety and immunogenicity of an inactivated quadrivalent influenza vacci...

journal_title：Vaccine

authors： Pépin S,Donazzolo Y,Jambrecina A,Salamand C,Saville M

更新日期：2013-11-12 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC), which produces heat labile toxin (LT) and/or heat stable toxin (ST), is considered to be the most common known cause of travellers' diarrhoea (TD). Owing to the antigenic similarity between cholera toxin and LT, immunization with inactivated oral B-subunit/whole-cell cholera va...

journal_title：Vaccine

authors： Leyten EM,Soonawala D,Schultsz C,Herzog C,Ligthelm RJ,Wijnands S,Visser LG

更新日期：2005-10-17 00:00:00

abstract：:Continuing investments in vaccine innovation are insufficiently translated into market entries of novel vaccines. This innovation paradox is in part caused by stakeholders lacking complete understanding of the complex array of steps necessary for vaccine development and collaboration difficulties between the wide vari...

journal_title：Vaccine

authors： Van de Burgwal LHM,Ribeiro CDS,Van der Waal MB,Claassen E

更新日期：2018-11-26 00:00:00

abstract：:The number of vaccines available and included as part of the national immunization schedules, has increased significantly over the past few decades. This impacts on patient/parent compliance and creates a challenge for health care providers for implementation of schedules necessitating training and infrastructure impr...

journal_title：Vaccine

authors： Visser A,Hoosen A

更新日期：2012-09-07 00:00:00

abstract：:The measurement of measles-specific neutralizing antibodies, directed against the surface measles virus hemagglutinin and fusion proteins, is considered the gold standard in measles serology. We assessed functional measles-specific neutralizing antibody levels in a racially diverse cohort of 763 young healthy adolesce...

journal_title：Vaccine

authors： Haralambieva IH,Ovsyannikova IG,O'Byrne M,Pankratz VS,Jacobson RM,Poland GA

更新日期：2011-06-15 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:Vaccines prevent an estimated 2.5 million deaths worldwide each year and are amongst the most cost-effective preventive measures against infectious diseases. Despite the effectiveness and availability of vaccines in many parts of the world, vaccination rates and service uptake remains suboptimal among both healthcare ...

journal_title：Vaccine

authors： Poudel A,Lau ETL,Deldot M,Campbell C,Waite NM,Nissen LM

更新日期：2019-09-20 00:00:00

abstract：OBJECTIVE:This study sought to evaluate the acceptability of inactivated influenza vaccine delivered by microneedle patch (MNP) in comparison to inactivated influenza vaccine (IIV) delivered by hypodermic needle. DESIGN, SETTING, AND PARTICIPANTS:From the general population of Atlanta, Georgia, we screened 112 and enr...

journal_title：Vaccine

authors： Frew PM,Paine MB,Rouphael N,Schamel J,Chung Y,Mulligan MJ,Prausnitz MR

更新日期：2020-10-21 00:00:00

abstract：:A short-term toxicity study was performed to investigate local reactions and haematological changes after intramuscular (i.m.) injection of meningococcal vaccine with a concentration of 25 or 50 micrograms protein ml-1. In these meningococcal vaccines up to 75 micrograms Zwittergent ml-1 was used to form a protein-det...

journal_title：Vaccine

authors： Speijers GJ,Danse LH,Beuvery EC,Derks HJ,Vos JG

更新日期：1988-10-01 00:00:00

abstract：:Since 1992, hepatitis B vaccine has been an integrated part of Thailand's expanded programme on immunisation (EPI). Based on the data from five representative provinces, we have evaluated its impact on the countrywide prevalence of HBV infection and carrier rate. The population studied comprised 400-488 healthy and im...

journal_title：Vaccine

authors： Poovorawan Y,Theamboonlers A,Vimolket T,Sinlaparatsamee S,Chaiear K,Siraprapasiri T,Khwanjaipanich S,Owatanapanich S,Hirsch P,Chunsuttiwat S

更新日期：2000-11-22 00:00:00

abstract：:Ten adult volunteers, with low prevaccination levels of serum IgG antibodies against meningococcal antigens (< 1 microg ml(-1)), received three doses of the Norwegian group B meningococcal outer membrane vesicle (OMV) vaccine intramuscularly at weeks 0, 6 and 46. Anti-OMV IgG subclass responses were measured and compa...

journal_title：Vaccine

authors： Naess LM,Aarvak T,Aase A,Oftung F,Høiby EA,Sandin R,Michaelsen TE

更新日期：1999-02-26 00:00:00