Anti-viral activity of sulfated chitin derivatives against Friend murine leukaemia and herpes simplex type-1 viruses.

abstract：BACKGROUND:RTS,S/AS01 is a safe and moderately efficacious vaccine considered for implementation in endemic Africa. Model predictions of impact and cost-effectiveness of this new intervention could aid in country adoption decisions. METHODS:The impact of RTS,S was assessed in 43 countries using an ensemble of models o...

journal_title：Vaccine

authors： Galactionova K,Tediosi F,Camponovo F,Smith TA,Gething PW,Penny MA

更新日期：2017-01-03 00:00:00

abstract：:We evaluated the effectiveness of the Jeryl Lynn strain vaccine in a large outbreak of mumps in Navarre, Spain, 2006-2008. Each of the 241 cases of mumps occurring in children over 15 months of age born between 1998 and 2005 was compared with 5 controls individually matched by sex, birth date, district of residence an...

journal_title：Vaccine

authors： Castilla J,García Cenoz M,Arriazu M,Fernández-Alonso M,Martínez-Artola V,Etxeberria J,Irisarri F,Barricarte A

更新日期：2009-03-26 00:00:00

abstract：:Tuberculosis caused by infection with Mycobacterium tuberculosis or Mycobacterium bovis remains one of the most important infectious diseases of man and animals. The current vaccine M. bovis Calmette-Guérin (BCG) demonstrates variable efficacy and so a more robust strategy to either replace, or more likely supplement ...

journal_title：Vaccine

authors： Logan KE,Chambers MA,Hewinson RG,Hogarth PJ

更新日期：2005-12-01 00:00:00

abstract：:Hepatitis A and B are common infections worldwide and their severity is related to the individual's age upon initial infection. Furthermore, when hepatitis B infection occurs in infants, the risk of becoming a chronic carrier is 90%. For hepatitis A, the lower incidence of disease arising from an improvement in living...

journal_title：Vaccine

authors： Van Damme P,Van der Wielen M

更新日期：2001-03-21 00:00:00

abstract：BACKGROUND:The primary prevention measure for influenza infection has been the use of influenza vaccines. However, even when the vaccine and circulating strains are well-matched, some healthy children do not respond to the vaccine, likely due to a genetic basis for immune hyporesponsiveness. The primary objective of th...

journal_title：Vaccine

authors： Narwaney KJ,Glanz JM,Norris JM,Fingerlin TE,Hokanson JE,Rewers M,Hambidge SJ

更新日期：2013-02-04 00:00:00

abstract：:The protection elicited by the intramuscular injection of two plasmid DNAs encoding Leishmania major cysteine proteinase type I (CPb) and type II (CPa) was evaluated in a murine model of experimental cutaneous leishmaniasis. BALB/c mice were immunized either separately or with a cocktail of the two plasmids expressing...

journal_title：Vaccine

authors： Rafati S,Salmanian AH,Taheri T,Vafa M,Fasel N

更新日期：2001-05-14 00:00:00

abstract：:Pseudomonas aeruginosa antimicrobial resistance is a major therapeutic challenge. DNA vaccination is an attractive approach for antigen-specific immunotherapy against P. aeruginosa. We explored the feasibility of employing Herpes simplex virus type 1 tegument protein, VP22, as a molecular tool to enhance the immunogen...

journal_title：Vaccine

authors： Yu X,Wang Y,Xia Y,Zhang L,Yang Q,Lei J

更新日期：2016-08-17 00:00:00

abstract：:The characterization of the cross-reactive, or heterologous, neutralizing antibody (NAb) responses developed during HIV-1-infection is relevant to the development of an HIV vaccine. Here we summarize our recently published study where we characterized the cross-reactive NAb responses in two cohorts of anti-retroviral ...

journal_title：Vaccine

authors： Sather DN,Stamatatos L

更新日期：2010-05-26 00:00:00

abstract：:Cytology-based screening has reduced cervical cancer mortality in countries able to implement, sustain and financially support organized programs that achieve broad coverage. These ongoing secondary prevention efforts considerably complicate the question of whether vaccination against human papillomavirus (HPV) types ...

journal_title：Vaccine

authors： Kim JJ,Brisson M,Edmunds WJ,Goldie SJ

更新日期：2008-08-19 00:00:00

abstract：:The amino terminal region of group A streptococcal M proteins evokes type-specific immunity while the conserved C-repeat epitopes evoke cross-protective immunity against multiple serotypes. The present studies were undertaken to compare the protective efficacy of vaccines containing either type-specific (hexavalent va...

journal_title：Vaccine

authors： Penfound TA,Chiang EY,Ahmed EA,Dale JB

更新日期：2010-07-12 00:00:00

abstract：:Since the production of influenza vaccines is complicated by the continuous variation of these viruses, it would be desirable to develop vaccines that induce cross-protective immunity against influenza virus strains that circulate in subsequent winter epidemics. We have recently demonstrated that antibodies induced af...

journal_title：Vaccine

authors： Rimmelzwaan GF,Baars M,van Amerongen G,van Beek R,Osterhaus AD

更新日期：2001-10-12 00:00:00

abstract：OBJECTIVES:To assess immunogenicity and safety of the 23-valent polysaccharide pneumococcal vaccine (PPV23) in juvenile idiopathic arthritis (JIA) patients under conventional DMARDs with or without anti-TNF therapy. The influences of demographic data, disease activity and treatment on immune response and the potential ...

journal_title：Vaccine

authors： Aikawa NE,França IL,Ribeiro AC,Sallum AM,Bonfa E,Silva CA

更新日期：2015-01-29 00:00:00

abstract：OBJECTIVE:To evaluate whether the social media strategy developed for the campaign Stop HPV - stop cervical cancer was successful at engaging target groups in communication regarding HPV vaccination. INTRODUCTION:In 2009, the Human Papillomavirus (HPV) vaccine became part of the Danish childhood vaccination program to...

journal_title：Vaccine

authors： Pedersen EA,Loft LH,Jacobsen SU,Søborg B,Bigaard J

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:In 2014 the Kenya National Immunization Technical Advisory Group (KENITAG) was asked by the Ministry of Health to provide an evidence-based recommendation on whether the seasonal influenza vaccine should be introduced into the national immunization program (NIP). METHODS:We reviewed KENITAG manuals, reports...

journal_title：Vaccine

authors： Dawa J,Chaves SS,Ba Nguz A,Kalani R,Anyango E,Mutie D,Muthoka P,Tabu C,Maritim M,Amukoye E,Were F,Kenya National Immunization Technical Advisory Group (KENITAG).

更新日期：2019-01-14 00:00:00

abstract：:This study was undertaken to estimate the magnitude of Bordetella pertussis infections in a highly vaccinated population in Israel in order to evaluate the relationship between clinical notification data and serology-based evidence of infection. A cross-sectional survey was conducted on a total of 1982 serum samples f...

journal_title：Vaccine

authors： Rendi-Wagner P,Tobias J,Moerman L,Goren S,Bassal R,Green M,Cohen D

更新日期：2010-04-26 00:00:00

abstract：:Leptospirosis is a zoonotic disease affecting animals and humans worldwide. Leptospiral infection in cattle can cause reproductive failure and reduced weight gain, and importantly, infection represents a significant disease risk for farmers. Current bacterin vaccines offer protection that is short-lived and restricted...

journal_title：Vaccine

authors： Murray GL,Lo M,Bulach DM,Srikram A,Seemann T,Quinsey NS,Sermswan RW,Allen A,Adler B

更新日期：2013-01-07 00:00:00

abstract：:Although concerns about safety of influenza vaccination during pregnancy have been raised in the past, vaccination of pregnant women was recommended in many countries during the 2009 A/H1N1 pandemic influenza. A retrospective cohort study was conducted to evaluate the risk of adverse maternal, fetal and neonatal outco...

journal_title：Vaccine

authors： Fabiani M,Bella A,Rota MC,Clagnan E,Gallo T,D'Amato M,Pezzotti P,Ferrara L,Demicheli V,Martinelli D,Prato R,Rizzo C

更新日期：2015-05-05 00:00:00

abstract：:A prototype H7 influenza vaccine constructed based on the H7N7 outbreak in 2003 was tested for the protective efficacy against the novel H7N9 virus in a lethal murine challenge model. Serum samples from vaccinated mice showed significant neutralizing activity against the H7N9 virus and the mice were completely protect...

journal_title：Vaccine

authors： Tang LH,Lim JH,Kuah LF,Lau YF

更新日期：2014-09-22 00:00:00

abstract：:Current available influenza vaccines are safe and effective in preventing influenza. Nevertheless, there is a need for influenza vaccines with improved efficacy in the elderly. This need is underscored by both the observation that influenza has a major clinical and economic impact in the elderly and the fact that curr...

journal_title：Vaccine

authors： de Bruijn IA,Nauta J,Cramer WC,Gerez L,Palache AM

更新日期：2005-07-08 00:00:00

abstract：:The O specific polysaccharide (OSP) of the lipopolysaccharide (LPS) of Salmonella enterica serovar Paratyphi A is a protective antigen and the target for vaccine development. LPS is the major constituent of the outer membrane of S. Paratyphi A with the OSP exposed on the surface, in addition to the cell associated LPS...

journal_title：Vaccine

authors： Kothari S,Kim JA,Kothari N,Jones C,Choe WS,Carbis R

更新日期：2014-05-01 00:00:00

abstract：:In a previous work we selected montanide ISA720 (M-ISA720) among different adjuvants for the vaccination with a V3 loop based multi-epitope polypeptide TAB9. In this paper we present the evaluation of the toxicity and immunogenicity of this formulation in non-human primates. TAB9 in M-ISA720 was highly immunogenic in ...

journal_title：Vaccine

authors： Gómez CE,Navea L,Lobaina L,Dubed M,Expósito N,Soto A,Duarte CA

更新日期：1999-05-04 00:00:00

abstract：:We aimed to estimate the effectiveness of H1N1/09 containing influenza vaccines against hospitalization from influenza in Australia. We performed a test-negative case control study in patients hospitalized in 15 sentinel Australian hospitals between March and November 2010, comparing influenza vaccination (H1N1/09 mon...

journal_title：Vaccine

authors： Cheng AC,Kotsimbos T,Kelly HA,Irving LB,Bowler SD,Brown SG,Holmes M,Jenkins CR,Thompson P,Simpson G,Wood-Baker R,Senanayake SN,Brady SJ,Paterson DL,Wark PA,Upham JW,Korman TM,Dwyer DE,Waterer GW,Kelly PM

更新日期：2011-10-06 00:00:00

abstract：:Virus-like particles (VLP) are inert, empty capsids of viruses, which contain no DNA/RNA from the virus itself. However they retain the structure of a virus and they can be engineered to have antigens attached. We have constructed VLP, derived from Rabbit hemorrhagic disease virus, and shown they are highly immunogeni...

journal_title：Vaccine

authors： Young SL,Wilson M,Wilson S,Beagley KW,Ward V,Baird MA

更新日期：2006-06-29 00:00:00

abstract：:In order to establish a firm preventive measure for tick-borne encephalitis (TBE) in Japan, we evaluated the immune response of European vaccine against Japanese TBE virus strain (Oshima 5-10) for man and mouse. Furthermore, the efficacy of pre- and post-exposure protection by a polyclonal rabbit anti-TBE virus serum ...

journal_title：Vaccine

authors： Chiba N,Osada M,Komoro K,Mizutani T,Kariwa H,Takashima I

更新日期：1999-03-17 00:00:00

abstract：:Respiratory mucosa immunization is capable of eliciting both local and distal mucosal immune responses; it is a potentially powerful yet largely unused modality for vaccination against respiratory diseases. Targeting the lower versus upper airways by aerosol delivery alters the immunogenicity profile of a vaccine, alt...

journal_title：Vaccine

authors： Bolton DL,Song K,Tomaras GD,Rao S,Roederer M

更新日期：2017-01-23 00:00:00

abstract：:In the European Union Viral Haemorrhagic Septicaemia (VHS) eradication is still based on stamping out. Due to the lack of effective low cost vaccines immune prophylaxis is currently not used to combat VHS. This paper describes a new oral delivery method for immunisation of trout with attenuated virus. The vaccine cons...

journal_title：Vaccine

authors： Adelmann M,Köllner B,Bergmann SM,Fischer U,Lange B,Weitschies W,Enzmann PJ,Fichtner D

更新日期：2008-02-06 00:00:00

abstract：:Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is highly heterogenic. This heterogeneity has an effect on antigenic composition of PRRSV and might create differences in sensitivity to neutralization between isolates. The sensitivity to neutralization could be an important feature of PRRSV isolates because...

journal_title：Vaccine

authors： Martínez-Lobo FJ,Díez-Fuertes F,Simarro I,Castro JM,Prieto C

更新日期：2011-09-16 00:00:00

abstract：BACKGROUND:US-bound refugees undergo required health assessments overseas to identify and treat communicable diseases of public health significance-such as pulmonary tuberculosis-before migration. Immunizations are not required, leaving refugees at risk for vaccine-preventable diseases. In response, the US Centers for ...

journal_title：Vaccine

authors： Mitchell T,Dalal W,Klosovsky A,Yen C,Phares C,Burkhardt M,Amin F,Froes I,Hamadeh A,Lynn SA,Quintanilla J,Doney AC,Cetron M,Weinberg M

更新日期：2021-01-03 00:00:00

abstract：:Paediatric patients with antibody deficiency may either be delayed in development of humoral immunity or may be persistently deficient in antibody production. To differentiate between these entities, we examined the 23-valent pneumococcal polysaccharide (PnPS) vaccine-induced IgM-, IgG- and IgA antibody responses in a...

journal_title：Vaccine

authors： Janssen WJ,Nierkens S,Sanders EA,Boes M,van Montfrans JM

更新日期：2015-11-17 00:00:00

abstract：:We investigated several methods to immunize the abomasum (fourth and gastric stomach) of kid goats by direct (abomasal) or distal (rectal or nasal) routes utilizing mucosal antigens isolated from the abomasal parasite, Haemonchus contortus. Direct (ultrasound guided), immunization of the abomasal mucosa together with ...

journal_title：Vaccine

authors： Jasmer DP,Brown WC,Parish S

更新日期：2011-04-05 00:00:00