Abstract：
:In 1994, 630 Gambian infants were immunized with three doses of the synthetic polypeptide malaria vaccine SPf66 or with a control vaccine. No significant protection against first or total attacks of malaria was observed among the children who received SPf66. However, the period of follow-up was short. Thus, 532 children were followed for a second malaria transmission season during which 291 episodes of malaria were detected. Protective efficacies of SPf66 against first attacks of malaria and against all attacks of malaria were 8% [95% CI-20%, 30%] and 2% [95% CI-26% 24%] respectively. SPf66 did not provide any significant degree of protection to Gambian infants during a second year of follow-up.
journal_name
Vaccinejournal_title
Vaccineauthors
Bojang KA,Obaro SK,D'Alessandro U,Bennett S,Langerock P,Targett GA,Greenwood BMdoi
10.1016/s0264-410x(97)00159-xsubject
Has Abstractpub_date
1998-01-01 00:00:00pages
62-7issue
1eissn
0264-410Xissn
1873-2518pii
S0264-410X(97)00159-Xjournal_volume
16pub_type
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