Abstract:
:Although the direct health impact of Coronavirus disease (COVID-19) pandemic on child health is low, there are indirect impacts across many aspects. We compare childhood vaccine uptake in three types of healthcare facilities in Singapore - public primary care clinics, a hospital paediatric unit, and private paediatrician clinics - from January to April 2020, to baseline, and calculate the impact on herd immunity for measles. We find a 25.6% to 73.6% drop in Measles-Mumps-Rubella (MMR) uptake rates, 0.4 - 10.3% drop for Diphtheria-Tetanus-Pertussis-inactivated Polio-Haemophilus influenza (5-in-1), and 8.0-67.8% drop for Pneumococcal conjugate vaccine (PCV) across all 3 sites. Consequent herd immunity reduces to 74-84% among 12-month- to 2-year-olds, well below the 95% coverage that is protective for measles. This puts the whole community at risk for a measles epidemic. Public health efforts are urgently needed to maintain efficacious coverage for routine childhood vaccines during the COVID-19 pandemic.
journal_name
Vaccinejournal_title
Vaccineauthors
Zhong Y,Clapham HE,Aishworiya R,Chua YX,Mathews J,Ong M,Wang J,Murugasu B,Chiang WC,Lee BW,Chin HLdoi
10.1016/j.vaccine.2020.12.054subject
Has Abstractpub_date
2021-01-29 00:00:00pages
780-785issue
5eissn
0264-410Xissn
1873-2518pii
S0264-410X(20)31634-0journal_volume
39pub_type
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