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A non-mitochondrial carboxylase, related to glutamate action is synthesized in the retina of the chick embryo.

Abstract：

:SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and Western blot of chick retinal proteins at 21 days after intravitreal injection with 5 or 10 microM/eye Glu showed decreases in 37, 42, 53 and 57 kDa proteins and increases in 35, 72 and >94 kDa proteins. These proteins were carboxylases except for the 35 and 37 kDa proteins. With > or =15 microM/eye Glu, non-specific loss of retinal proteins was observed. In embryonic retinas, the 42 kDa protein was seen a few days before hatching, with biotin incorporation on days 3-6 after hatching. Immunohistochemistry indicated that this protein was a component of both the inner nuclear layer and the photoreceptor. Immunocytochemistry located it to the cell surface.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Sattayasai N,Sattayasai J,Daduang S,Chahomchuen T,Ketkaew S,Puchongkavarin H

doi

10.1016/s0165-5728(03)00173-5

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

104-11

issue

1-2

eissn

0165-5728

issn

1872-8421

pii

S0165572803001735

journal_volume

141

pub_type

杂志文章

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