Abstract:
:Numerous types of age-related deficits in the nervous system have been well documented. While a distinction between general types of memories that are susceptible to compromise with advanced age has been fairly well agreed upon, it is often difficult to determine exactly which specific processes are detrimentally influenced. In this study, we used a paradigm that enabled us to distinguish between effects associated with gross motor deficits and those due to learning and memory of a motor skill, per se. In terms of both latency and errors, senescent animals were, on average, impaired in their ability to traverse an elevated obstacle course, compared to younger animals. Yet, if gross motor abilities are accounted for, a fraction of these deficits is readily explained. Moreover, if individual baseline performance differences are normalized, no memory differences are evident across age groups. These observations suggest that memory for a procedural task is not impaired with advanced age.
journal_name
Neurobiol Agingjournal_title
Neurobiology of agingauthors
Churchill JD,Stanis JJ,Press C,Kushelev M,Greenough WTdoi
10.1016/s0197-4580(02)00194-xsubject
Has Abstractpub_date
2003-10-01 00:00:00pages
883-92issue
6eissn
0197-4580issn
1558-1497pii
S019745800200194Xjournal_volume
24pub_type
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