Abstract：
:Alcoholic drinks are capable of triggering a wide range of allergic and allergic-like responses, including rhinitis, itching, facial swelling, headache, cough and asthma. Limited epidemiological data suggests that many individuals are affected and that sensitivities occur to a variety of drinks, including wine, beer and spirits. In surveys of asthmatics, over 40% reported the triggering of allergic or allergic-like symptoms following alcoholic drink consumption and 30 - 35% reported worsening of their asthma. Sensitivity to ethanol itself can play a role in triggering adverse responses, particularly in Asians, which is due mainly to a reduced capacity to metabolize acetaldehyde. In Caucasians, specific non-alcohol components are the main cause of sensitivities to alcoholic drinks. Allergic sensitivities to specific components of beer, spirits and distilled liquors have been described. Wine is clearly the most commonly reported trigger for adverse responses. Sensitivities to wine appear to be due mainly to pharmacological intolerances to specific components, such as biogenic amines and the sulphite additives. Histamine in wine has been associated with the triggering of a wide spectrum of adverse symptoms, including sneezing, rhinitis, itching, flushing, headache and asthma. The sulphite additives in wine have been associated with triggering asthmatic responses. Clinical studies have confirmed sensitivities to the sulphites in wine in limited numbers of individuals, but the extent to which the sulphites contribute to wine sensitivity overall is not clear. The aetiology of wine-induced asthmatic responses may be complex and may involve several co-factors.
journal_name
Addict Bioljournal_title
Addiction biologyauthors
Vally H,Thompson PJdoi
10.1080/1355621031000069828subject
Has Abstractpub_date
2003-03-01 00:00:00pages
3-11issue
1eissn
1355-6215issn
1369-1600pii
ELEKYPADVWYMWX37journal_volume
8pub_type
杂志文章,评审abstract：:We examined whether acute administration of phencyclidine (PCP), an antagonist of the N-methyl-D-aspartate (NMDA) receptor-channel complex, can cause neuronal toxicity that is associated with apoptosis. Three- and 24-month-old rats were placed in locomotor activity chambers. PCP (50 mg/kg) or saline (0.15 M NaCl) were...
journal_title：Addiction biology
pub_type： 杂志文章
doi：10.1080/13556210050003748
更新日期：2000-04-01 00:00:00
abstract：:Ethyl glucuronide (EtG) is a promising new biological state marker of recent alcohol consumption that detects alcohol use reliably over a definite time period. Other currently available markers lack acceptable sensitivity and specificity. Our aim is to elucidate under naturalistic conditions the time course of EtG exc...
journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2002-10-01 00:00:00
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journal_title：Addiction biology
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journal_title：Addiction biology
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journal_title：Addiction biology
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2012-09-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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journal_title：Addiction biology
pub_type： 杂志文章,评审
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2020-07-01 00:00:00
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journal_title：Addiction biology
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更新日期：2006-06-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：1997-07-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
doi：10.1111/adb.13001
更新日期：2021-01-28 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2018-01-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2018-01-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2014-01-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2000-10-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2012-11-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：1999-07-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：1999-01-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2001-09-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：1998-07-01 00:00:00
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journal_title：Addiction biology
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更新日期：2015-09-01 00:00:00
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journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：1999-10-01 00:00:00
abstract：:Dysregulation of histone deacetylases (HDAC) has been proposed as a potential contributor to aberrant transcriptional profiles that can lead to changes in cognitive functions. It is known that METH negatively impacts the prefrontal cortex (PFC) leading to cognitive decline and addiction whereas modafinil enhances cogn...
journal_title：Addiction biology
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
