Differences in the betaC-S lyase activities of viridans group streptococci.

abstract：:Hemin (iron protoporphyrin IX) is a necessary component of many proteins, functioning either as a cofactor or an intracellular messenger. Hemoproteins have diverse functions, such as transportation of gases, gas detection, chemical catalysis and electron transfer. Stanniocalcin 1 (STC1) is a protein involved in respir...

journal_title：Biochemical and biophysical research communications

authors： Westberg JA,Jiang J,Andersson LC

更新日期：2011-06-03 00:00:00

abstract：:Polychlorinated dibenzo-p-dioxins (PCDDs) are known as g environmental contaminants on account of the extreme toxicity. Among these compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TetraCDD) is regarded as the most toxic one. The extremely high toxicity of 2,3,7,8-TetraCDD is based on its high affinity for Ah r...

journal_title：Biochemical and biophysical research communications

authors： Shinkyo R,Sakaki T,Takita T,Ohta M,Inouye K

更新日期：2003-08-29 00:00:00

abstract：:Hypoxic/ischemic trauma is a primary factor in the pathology of various disease states. Yet, very little is known about the molecular mechanisms involved in cellular responses and adaptations to hypoxia. As a means of identifying intracellular signaling systems that are regulated in response to hypoxia, the effects of...

journal_title：Biochemical and biophysical research communications

authors： Beitner-Johnson D,Leibold J,Millhorn DE

更新日期：1998-01-06 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta) has been implicated in the development of diabetic glomerulopathy. In order to evaluate a role of Smad3, one of the major signaling molecules downstream of TGF-beta, in the pathogenesis of diabetic glomerulopathy, Smad3-null mice were made diabetic with streptozotocin injecti...

journal_title：Biochemical and biophysical research communications

authors： Fujimoto M,Maezawa Y,Yokote K,Joh K,Kobayashi K,Kawamura H,Nishimura M,Roberts AB,Saito Y,Mori S

更新日期：2003-06-13 00:00:00

abstract：:Primary effusion lymphoma (PEL) is an aggressive neoplasm caused by Kaposi's sarcoma-associated herpesvirus (KSHV). This study provides evidence that proteasomal activity is required for both survival of PEL cells stably harboring the KSHV genome and viral replication of KSHV. We evaluated the cytotoxic effects of pro...

journal_title：Biochemical and biophysical research communications

authors： Saji C,Higashi C,Niinaka Y,Yamada K,Noguchi K,Fujimuro M

更新日期：2011-12-02 00:00:00

abstract：:The carcinogenic function of arachidonate lipoxygenase12 (Alox12) has been reported in various cancers. However, little is known on the role of Alox12 in lung cancer. Here, we demonstrate that Alox12 is upregulated and contributes to biological activities of lung cancer through multiple mechanisms. We found that Alox1...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Tong W,Liao M,Chen D

更新日期：2020-04-16 00:00:00

abstract：:Endochondral ossification is a crucial process for longitudinal growth of bones. Differentiating chondrocytes in growth cartilage form four sequential zones of proliferation, alignment into column, hypertrophy, and substitution of chondrocytes with osteoblasts. Wnt/β-catenin signaling is essential for differentiation ...

journal_title：Biochemical and biophysical research communications

authors： Takegami Y,Ohkawara B,Ito M,Masuda A,Nakashima H,Ishiguro N,Ohno K

更新日期：2016-04-22 00:00:00

abstract：:Serotype conversion (O-antigen glucosylation) in Shigella flexneri is mediated by temperate bacteriophages, which encode a three-gene cluster that contains gtrA, gtrB, and gtr([type]). Sequence analysis has revealed that gtrA and gtrB are conserved and readily interchangeable between serotypes. The gtr([type]) is uniq...

journal_title：Biochemical and biophysical research communications

authors： Korres H,Mavris M,Morona R,Manning PA,Verma NK

更新日期：2005-03-25 00:00:00

abstract：:An organic extract of Nitzschia alba cells possesses ionophoretic activity towards silicate, as it induces silicate transport across an organic phase or across synthetic lipid membranes. The activity is dependent upon Na+ and prefers silicon to germanium, a congener. The activity can be resolved into two apparently pu...

journal_title：Biochemical and biophysical research communications

authors： Bhattacharyya P,Volcani BE

更新日期：1983-07-18 00:00:00

abstract：:The death of cardiomyocytes after myocardial infarction (MI) often leads to ventricular remodeling as well as heart failure (HF). The cardiac progenitor cells (CPCs) have the ability to regenerate functional heart muscle in patients after MI, which provides a promising method for MI-induced HF therapy. However, to dat...

journal_title：Biochemical and biophysical research communications

authors： Li L,Wang Q,Yuan Z,Chen A,Liu Z,Wang Z,Li H

更新日期：2018-05-15 00:00:00

abstract：:Tamoxifen (TAM), an anti-estrogen compound, is widely used for chemotherapy of breast cancer, although the molecular mechanisms underlying TAM cytotoxicity are obscure. Here, we show that TAM dramatically caused degradation of vimentin (VIM) in human skin fibroblasts, in a time and dose dependent manner. Addition of c...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto M,Inoue S,Ogawa S,Conrad C,Muramatsu M,Shackelford D,Masliah E

更新日期：1998-06-18 00:00:00

abstract：:Choroidal neovascularization (CNV) is a type of wet age-related macular degeneration (AMD) which is a major cause of blindness in elder patients. Tumor necrosis factor receptor-associated factor 6 (TRAF6) promotes tumor angiogenesis via upregulating the expression of hypoxia-inducible factor 1α (HIF-1α) and vascular e...

journal_title：Biochemical and biophysical research communications

authors： Ding D,Zhu M,Liu X,Jiang L,Xu J,Chen L,Liang J,Li L,Zhou T,Wang Y,Shi H,Yuan Y,Song E

更新日期：2018-09-18 00:00:00

abstract：:Dynamic properties of spin-labelled heterosaccharides in the Fc-region of murine monoclonal antihapten immunoglobulin G were studied in model immune complexes (IC) as a function of the IC size. Model IC dimers, trimers and oligomers were formed using bivalent photoaffinity antigens. The ESR spectrum exhibits two compo...

journal_title：Biochemical and biophysical research communications

authors： Kusumi A,Winkelhake JL

更新日期：1986-05-29 00:00:00

abstract：:Glutathione (GSH) is the most abundant non-protein thiol that buffers reactive oxygen species in the brain. GSH does not reduce nitroxides directly, but in the presence of ascorbates, addition of GSH increases ascorbate-induced reduction of nitroxides. In this study, we used electron paramagnetic resonance (EPR) imagi...

journal_title：Biochemical and biophysical research communications

authors： Emoto MC,Matsuoka Y,Yamada KI,Sato-Akaba H,Fujii HG

更新日期：2017-04-15 00:00:00

abstract：:Bovine retinal rod outer segment membranes are enriched in a phosphoinositide-specific phosphodiesterase (phospholipase C) activity strictly modulated by free calcium ion concentration. The enzyme(s) was highly active on phosphatidylinositol 4,5-bisphosphate: maximal hydrolysis rate was attained at 10(-5)M Ca2+ and ac...

journal_title：Biochemical and biophysical research communications

authors： Panfoli I,Morelli A,Pepe I

更新日期：1990-11-30 00:00:00

abstract：:C-C chemokine receptor 7 (CCR7) and its ligands CCL19 contributes to the directional migration of certain cancer cell lines, but its role in the migration of BMSCs remains vague. The aim of this study was to determine the possible interaction between CCL19-induced conditions and matrix metalloproteinases-9 (MMP9) expr...

journal_title：Biochemical and biophysical research communications

authors： Zhang W,Tu G,Lv C,Long J,Cong L,Han Y

更新日期：2014-08-22 00:00:00

abstract：:MicroRNAs (miRNAs) are small RNA molecules, which act as post-transcriptional regulators of a gene expression, with important functions within the cell physiology. Whilst many authors have focused on the study of miRNA expression in physiological and pathological processes, various technical variables related to miRNA...

journal_title：Biochemical and biophysical research communications

authors： Mraz M,Malinova K,Mayer J,Pospisilova S

更新日期：2009-12-04 00:00:00

abstract：:The α1,3/4-fucosyltransferases (FUT) subfamily are key enzymes in cell surface antigen synthesis during various biological processes. A novel role of FUTs in tumorigenesis has been discovered recently, however, the underlying mechanism remains largely unknown. Here, we characterized FUT6, a member of α1,3/4-FUT subfam...

journal_title：Biochemical and biophysical research communications

authors： Guo Q,Guo B,Wang Y,Wu J,Jiang W,Zhao S,Qiao S,Wu Y

更新日期：2012-01-06 00:00:00

abstract：:Cardiac differentiation involves a cascade of coordinated gene expression that regulates cell proliferation and matrix protein formation in a defined temporo-spatial manner. The zinc-finger-containing transcription factor has been implicated as a critical regulator of multiple cardiac-expressed genes as well as a regu...

journal_title：Biochemical and biophysical research communications

authors： Liu H,Zhu C,Luo J,Wang Y,Li D,Li Y,Zhou J,Yuan W,Ou Y,Liu M,Wu X

更新日期：2004-07-16 00:00:00

abstract：:Full activation of T lymphocytes transiently downregulates the steady state level of the tyrosine kinase p56(lck) mRNA. Here, we show that a decrease in messenger stability is involved in this downmodulation followed thereafter by a rapid and marked increase in mRNA half-life. In order to facilitate the study of p56(l...

journal_title：Biochemical and biophysical research communications

authors： Vanhée-Brossollet C,Vaquero C

更新日期：1997-04-17 00:00:00

abstract：:Plant innate immunity varies with age and plant developmental stages. Recently, we reported that Arabidopsis thaliana microRNA miR172b regulates FLS2 transcription through two transcription factors: TARGET OF EAT1 (TOE1) and TOE2. Although the flg22-triggered immune responses were investigated in 2-d-old or even young...

journal_title：Biochemical and biophysical research communications

authors： Zou Y,Wang S,Lu D

更新日期：2020-10-22 00:00:00

abstract：:Gaf-1/Rip11 encoded by the clone KIAA0857 participates in endosomal recycling through the interaction with both gamma-SNAP, a member of the soluble NSF attachment protein family, and a small GTPase, Rab11. Gaf-1/Rip11 and other Rab11-interacting proteins constitute a novel protein family that is involved in the endocy...

journal_title：Biochemical and biophysical research communications

authors： Kawase K,Shibata M,Kawashima H,Hatsuzawa K,Nagahama M,Tagaya M,Tani K

更新日期：2003-04-18 00:00:00

abstract：:Platelet activation (cytosolic [Ca2+] increase, aggregation and ATP secretion) was induced with A1F-4. This agent presumably interacts with a G protein which appears to mediate the coupling of the receptors for Ca mobilizing hormones and phospholipase C. All the A1F-4 evoked responses were inhibited by treatment with ...

journal_title：Biochemical and biophysical research communications

authors： Doni MG,Deana R,Bertoncello S,Zoccarato F,Alexandre A

更新日期：1988-11-15 00:00:00

abstract：:We have compared the coupling of human alpha(1A)-, alpha(1B)-, and alpha(1D)-adrenoceptors (expressed at approximately 2000 fmol/mg protein in Chinese hamster ovary cells) to cellular growth promotion (as assessed by [(3)H]thymidine incorporation) and related signaling mechanisms. Maximum elevation of intracellular Ca...

journal_title：Biochemical and biophysical research communications

authors： Keffel S,Alexandrov A,Goepel M,Michel MC

更新日期：2000-06-16 00:00:00

abstract：:RANTES is a potent chemotactic and activating agent for a variety of leukocytes including T-lymphocytes. To identify the region of the molecule responsible for this activity, we have made overlapping 10 amino acid peptides scanning the protein. A micro-Boyden chamber chemotaxis assay showed the most efficacious peptid...

journal_title：Biochemical and biophysical research communications

authors： Wells TN,Guye-Coulin F,Bacon KB

更新日期：1995-06-06 00:00:00

abstract：:Abnormal plasma ascorbic acid (AA) and dehydroascorbic acid (DHAA) levels observed in diabetes may be correlated to a deficiency in the recycling of AA. Ascorbic acid and DHAA levels are altered in diabetic liver in the present study. In addition, a coupling of the hexose monophosphate (HMP) shunt by way of NADPH to g...

journal_title：Biochemical and biophysical research communications

authors： Bode AM,Yavarow CR,Fry DA,Vargas T

更新日期：1993-03-31 00:00:00

abstract：:Murine embryonic stem cell (mESC)-derived cardiomyocytes represent a promising source of cells for use in the development of models for studying early cardiac development as well as cell-based therapies in postnatal pathologies. Here, we report a highly efficient cardiac differentiation system in which high density em...

journal_title：Biochemical and biophysical research communications

authors： Lee MY,Cagavi Bozkulak E,Schliffke S,Amos PJ,Ren Y,Ge X,Ehrlich BE,Qyang Y

更新日期：2011-12-09 00:00:00

abstract：:Prolactin, the Janus kinase 2 (JAK2) and the signal transducer and activator of transcription 5 (STAT5) are important for mammary gland development and have also been implicated in development and growth of breast tumors. In the present study we have investigated the role for JAK2 in proliferation, differentiation, an...

journal_title：Biochemical and biophysical research communications

authors： Olsen H,Hedengran Faulds MA,Saharinen P,Silvennoinen O,Haldosén LA

更新日期：2002-08-09 00:00:00

abstract：:This report describes the in vivo phosphorylation of isocitrate lyase and examines the possible consequences to the control of the Kreb's cycle and glyoxylate bypass. NADP-specific isocitrate dehydrogenase from E. coli was the first bacterial protein whose enzymic activity was shown to be modulated by reversible phosp...

journal_title：Biochemical and biophysical research communications

authors： Hoyt JC,Reeves HC

更新日期：1988-06-16 00:00:00

abstract：:Gene delivery has become an important tool for biological research and gene therapy trials. Lentiviral vector (LV) mediated gene transfer is a preferred approach for stable, sustained transgenic expression. We report here step-wise development of an Indian human immunodeficiency virus type 2 (HIV-2) isolate derived th...

journal_title：Biochemical and biophysical research communications

authors： Santhosh CV,Tamhane MC,Kamat RH,Patel VV,Mukhopadhyaya R

更新日期：2008-07-04 00:00:00