The extracellular matrix as a scaffold for tissue reconstruction.

abstract：:The immune system plays an indispensable role in the process of tissue regeneration following damage as well as during homeostasis. Inflammation and immune cell recruitment are signs of early onset injury. At the wound site, immune cells not only help to clear debris but also secrete numerous signalling molecules that...

journal_title：Seminars in cell & developmental biology

authors： Abnave P,Ghigo E

更新日期：2019-03-01 00:00:00

abstract：:Angiosperms display a huge variety of floral forms. The development of the ABC-model for floral organ identity, almost 20 years ago, has created an excellent basis for comparative floral development (evo-devo) studies. These have resulted in an increasingly more detailed understanding of the molecular control circuitr...

journal_title：Seminars in cell & developmental biology

authors： Rijpkema AS,Vandenbussche M,Koes R,Heijmans K,Gerats T

更新日期：2010-02-01 00:00:00

abstract：:Recent appraisals of mesenteric anatomy clarify its structure and show a continuous and helical-shaped organ. This new model signifies a departure from the conventional model which described multiple, separate "mesenteries". Renaissance anatomists depicted the mesentery as a continuous structure. Events that led to re...

journal_title：Seminars in cell & developmental biology

authors： Byrnes KG,Walsh D,Lewton-Brain P,McDermott K,Coffey JC

更新日期：2019-08-01 00:00:00

abstract：:The capacity of cells and animals to sense and adapt to fluctuations in the availability of energetic substrates is commonly described as metabolic flexibility. This flexibility allows for example the transition from fed to fasting states and to meet the energy demands of exercise in both states. Flexibility is disrup...

journal_title：Seminars in cell & developmental biology

authors： Bosch M,Parton RG,Pol A

更新日期：2020-12-01 00:00:00

abstract：:Ascidians are urochordates, marine invertebrates with non-feeding motile chordate tadpole larvae, except in the family Molgulidae. Urodele, or tailed, Molgulids have typical ascidian chordate tadpole larvae possessing tails with muscle cells, a notochord, and a dorsal hollow nerve cord. In contrast, anural (or tail-le...

journal_title：Seminars in cell & developmental biology

authors： Huber JL,da Silva KB,Bates WR,Swalla BJ

更新日期：2000-12-01 00:00:00

abstract：:Since their initial discovery in yeast, cyclin-dependent kinases have proven to be universal regulators of the cell cycle in all eukaryotes. In unicellular eukaryotes, cell cycle progression is principally governed by one catalytic subunit (cyclin-dependent kinase) that pairs with cell cycle-specific regulatory subuni...

journal_title：Seminars in cell & developmental biology

authors： Sánchez I,Dynlacht BD

更新日期：2005-06-01 00:00:00

abstract：:The endoplasmic reticulum (ER) is an intracellular compartment devoted to the synthesis, segregation and folding of soluble and membrane secretory proteins. Some mutations in these proteins lead to their incorrect or incomplete folding in the ER. The ER has a quality control system which detects misfolded proteins and...

journal_title：Seminars in cell & developmental biology

authors： Chevet E,Jakob CA,Thomas DY,Bergeron JJ

更新日期：1999-10-01 00:00:00

abstract：:Both types of Drosophila egg chamber germ cells, i.e. oocyte and nurse cells, have to control their nucleus positions in order to produce a viable gamete. Interestingly, while actin microfilaments are crucial to position the nuclei in nurse cells, these are the microtubules that are important for oocyte nucleus to mig...

journal_title：Seminars in cell & developmental biology

authors： Bernard F,Lepesant JA,Guichet A

更新日期：2018-10-01 00:00:00

abstract：:The urinary collecting system is derived from an epithelial protrusion arising from the Wolffian duct called the ureteric bud (UB) by the signal from its inductive tissue, metanephric mesenchyme (MM). Targeted gene mutation studies have shown that several transcription factors and MM-secreted glial cell line-derived n...

journal_title：Seminars in cell & developmental biology

authors： Sakurai H

更新日期：2003-08-01 00:00:00

abstract：:The intermediate mesoderm is located between the somites and the lateral plate mesoderm and gives rise to renal progenitors that contribute to the three mammalian kidney types (pronephros, mesonephros and metanephros). In this review, focusing largely on murine kidney development, we examine how the intermediate mesod...

journal_title：Seminars in cell & developmental biology

authors： Davidson AJ,Lewis P,Przepiorski A,Sander V

更新日期：2019-07-01 00:00:00

abstract：:Controlling gene expression is one of the most fundamental task of living organisms, from prokaryotes to higher eukaryotes, in order to develop, grow, and reproduce in an ever changing environment. In many cases, the expression status of a given gene is controlled independently of that of its neighbours through locali...

journal_title：Seminars in cell & developmental biology

authors： Rougeulle C,Avner P

更新日期：2003-12-01 00:00:00

abstract：:Complement and dendritic cells (DCs) share many functional features that drive the outcome of immune-inflammatory processes. Both have a sentinel function, acting as danger sensors specialized for a rapid, comprehensive and selective action against potential threats without damaging the healthy host cells. But while c...

journal_title：Seminars in cell & developmental biology

authors： Luque A,Serrano I,Aran JM

更新日期：2019-01-01 00:00:00

abstract：:By the development of information theory in 1948 by Claude Shannon to address the problems in the field of data storage and data communication over (noisy) communication channel, it has been successfully applied in many other research areas such as bioinformatics and systems biology. In this manuscript, we attempt to ...

journal_title：Seminars in cell & developmental biology

authors： Mousavian Z,Díaz J,Masoudi-Nejad A

更新日期：2016-03-01 00:00:00

abstract：:Understanding how some animals are immortal and avoid the ageing process is important. We currently know very little about how they achieve this. Research with genetic model systems has revealed the existence of conserved genetic pathways and molecular processes that affect longevity. Most of these established model o...

journal_title：Seminars in cell & developmental biology

authors： Sahu S,Dattani A,Aboobaker AA

更新日期：2017-10-01 00:00:00

abstract：:Drosophila Rhomboid-1 was discovered to be the first known intramembrane serine protease about 7 years ago. The study of the rhomboid-like family has since blossomed, and the purpose of this review is to take stock of where the field is, and how it may progress in the next few years. Three major themes are the increas...

journal_title：Seminars in cell & developmental biology

authors： Freeman M

更新日期：2009-04-01 00:00:00

abstract：:In the recent years several papers and some reviews have dealt with characterization, localization and influence on the precipitation of calcium carbonate, of the organic matrix from scleractinian corals. In fact, it has been well established that coral calcification is a biological controlled process orchestrated in ...

journal_title：Seminars in cell & developmental biology

authors： Falini G,Fermani S,Goffredo S

更新日期：2015-10-01 00:00:00

abstract：:Embryonic cultured Xenopus spinal neurons generate two types of spontaneous elevation of intracellular calcium that encode developmental information in the frequency with which they are produced. Calcium spikes regulate the appearance of GABA and maturation of potassium current. Calcium waves in growth cones regulate ...

journal_title：Seminars in cell & developmental biology

authors： Spitzer NC,Gu X

更新日期：1997-02-01 00:00:00

abstract：:Flies escape danger by jumping into the air and flying away. The giant fibre system (GFS) is the neural circuit that mediates this simple behavioural response to visual stimuli. The sensory signal is received by the giant fibre and relayed to the leg and wing muscle motorneurons. Many of the neurons in the Drosophila ...

journal_title：Seminars in cell & developmental biology

authors： Allen MJ,Godenschwege TA,Tanouye MA,Phelan P

更新日期：2006-02-01 00:00:00

abstract：:Lymphatic contractile dysfunction is central to a number of pathologies that affect millions of people worldwide. Due to its critical role in the process of inflammation, a dysfunctional lymphatic system also compromises the immune response, further exacerbating a number of inflammation related diseases. Despite the c...

journal_title：Seminars in cell & developmental biology

authors： Chakraborty S,Davis MJ,Muthuchamy M

更新日期：2015-02-01 00:00:00

abstract：:Can plants perceive sound? And what sounds are they likely to be "listening" to? The environment of plants includes many informative sounds, produced by biotic and abiotic sources. An ability to respond to these sounds could thus have a significant adaptive value for plants. We suggest the term phytoacoustics to descr...

journal_title：Seminars in cell & developmental biology

authors： Khait I,Obolski U,Yovel Y,Hadany L

更新日期：2019-08-01 00:00:00

abstract：:The mechanistic (or mammalian) Target of Rapamycin Complex 1 (mTORC1) is a central regulator of cell growth and metabolism. By integrating mitogenic signals, mTORC1-dependent phosphorylation of substrates dictates the balance between anabolic, pro-growth and catabolic, recycling processes in the cell. The discovery th...

journal_title：Seminars in cell & developmental biology

authors： Carroll B

更新日期：2020-11-01 00:00:00

abstract：:The sympathetic nervous system represents a critical mechanism for homoeostatic blood pressure regulation in humans. This review focuses on age-related alterations in neurocirculatory regulation in men and women by highlighting human studies that examined the relationship between muscle sympathetic nerve activity (MSN...

journal_title：Seminars in cell & developmental biology

authors： Klassen SA,Joyner MJ,Baker SE

更新日期：2021-01-16 00:00:00

abstract：:Hepatic oval cell activation, proliferation, and differentiation has been observed under certain physiological conditions, mainly when the proliferation of existing hepatocytes has been inhibited followed by severe hepatic injury. Hepatic oval cells display a distinct phenotype and have been shown to be a bipotential ...

journal_title：Seminars in cell & developmental biology

authors： Oh SH,Hatch HM,Petersen BE

更新日期：2002-12-01 00:00:00

abstract：:There has been widespread speculation regarding the possibility of reprogramming human somatic nuclei by transfer into oocytes. Stem cells derived from such reconstructed embryos could theoretically provide a source of autologous tissue for therapeutic transplantation. However the biological, technical and ethical hur...

journal_title：Seminars in cell & developmental biology

authors： Kind A,Colman A

更新日期：1999-06-01 00:00:00

abstract：:The ability of cells to polarize is an intrinsic property of almost all cells and is required for the devlopment of most multicellular organisms. To develop cell polarity, cells integrate various signals derived from intrinsic as well as extrinsic sources. In the recent years, cell-cell adhesion receptors have turned ...

journal_title：Seminars in cell & developmental biology

authors： Ebnet K,Kummer D,Steinbacher T,Singh A,Nakayama M,Matis M

更新日期：2018-09-01 00:00:00

abstract：:One of the characteristics of eukaryotic cells is their structural plasticity associated with the ability to carry out a broad range of complex functions, both autonomously and as components of tissues and organs. Major cellular rearrangements can be observed in various systems from meiosis in fission yeast, through d...

journal_title：Seminars in cell & developmental biology

authors： Lee YL,Burke B

更新日期：2018-10-01 00:00:00

abstract：:Embryonic patterning of the mouse during gastrulation and early organogenesis engenders the specification of anterior versus posterior structures and body laterality by the interaction of signalling and modulating activities. A group of cells in the mouse gastrula, characterised by the expression of a repertoire of "o...

journal_title：Seminars in cell & developmental biology

authors： Robb L,Tam PP

更新日期：2004-10-01 00:00:00

abstract：:Neural stem cells (NSCs) are subscribed extraordinary potential in repair of the damaged nervous system. However, the molecular identity of NSCs has not been established. Most NSC cultures contain large numbers of multipotent, bipotent, and lineage restricted neural progenitors, the majority of which appear to lose ne...

journal_title：Seminars in cell & developmental biology

authors： Sun YE,Martinowich K,Ge W

更新日期：2003-06-01 00:00:00

abstract：:Hypoxic exposure of cells or organisms induces expression of a number of hypoxia responsive genes through the activation of the hypoxia-inducible factor-1 (HIF-1). One of the most prominent HIF-1 targets is erythropoietin that has beneficial effects on ischemia-related injury in the brain. Exposure to low environmenta...

journal_title：Seminars in cell & developmental biology

authors： Grimm C,Hermann DM,Bogdanova A,Hotop S,Kilic U,Wenzel A,Kilic E,Gassmann M

更新日期：2005-08-01 00:00:00

abstract：:During the course of their classic experiments, Hilde Mangold and Hans Spemann discovered that the dorsal blastopore lip of an amphibian gastrula was able to induce formation of a complete embryonic axis when transplanted into the ventral side of a host gastrula embryo. Since then, the inducing activity of the dorsal ...

journal_title：Seminars in cell & developmental biology

authors： Thisse B,Thisse C

更新日期：2015-06-01 00:00:00