Purposeful patterns of spontaneous calcium transients in embryonic spinal neurons.

Abstract:

:Embryonic cultured Xenopus spinal neurons generate two types of spontaneous elevation of intracellular calcium that encode developmental information in the frequency with which they are produced. Calcium spikes regulate the appearance of GABA and maturation of potassium current. Calcium waves in growth cones regulate neurite extension. Spikes and waves are also observed in neurons differentiating in situ. Because differentiation is dependent on the frequency of calcium transients, neurons that are coactive and fire spikes in concert would be expected to differentiate together. Consistent with this prediction, segmentally arrayed clusters of putative motoneurons on the ventral aspect of the neural tube fire together during development.

journal_name

Semin Cell Dev Biol

authors

Spitzer NC,Gu X

doi

10.1006/scdb.1996.0116

subject

Has Abstract

pub_date

1997-02-01 00:00:00

pages

13-9

issue

1

eissn

1084-9521

issn

1096-3634

pii

S1084-9521(96)90116-0

journal_volume

8

pub_type

杂志文章
  • Cholesterol trafficking in the secretory and endocytic systems.

    abstract::Cells maintain a cholesterol gradient across the secretory system, with the lowest concentrations in the endoplasmic reticulum (ER) and the highest in the plasma membrane (PM). Cholesterol is also heterogeneously distributed in the endocytic pathway. Little is known about how this heterogeneous distribution of cholest...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1084-9521(02)00048-4

    authors: Prinz W

    更新日期:2002-06-01 00:00:00

  • Chemoaffinity in topographic mapping revisited--is it more about fiber-fiber than fiber-target interactions?

    abstract::Axonal projections between two populations of neurons, which preserve neighborhood relationships, are called topographic. They are ubiquitous in the brain. The development of the retinotectal projection, mapping the retinal output onto the roof of the midbrain, has been studied for decades as a model system. The rigid...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2014.07.010

    authors: Weth F,Fiederling F,Gebhardt C,Bastmeyer M

    更新日期:2014-11-01 00:00:00

  • Extrinsic information influences taste and flavor perception: a review from psychological and neuroimaging perspectives.

    abstract::The perception of taste and flavor can be greatly biased by extrinsic cues, or the information about a food that comes from outside of the food itself, such as package designs, brands, prices, and so on. In order to understand taste/flavor experiences in a broader context, it is necessary to consider factors other tha...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2012.11.001

    authors: Okamoto M,Dan I

    更新日期:2013-03-01 00:00:00

  • Single cells get together: High-resolution approaches to study the dynamics of early mouse development.

    abstract::Embryonic development is a complex and highly dynamic process during which individual cells interact with one another, adopt different identities and organize themselves in three-dimensional space to generate an entire organism. Recent technical developments in genomics and high-resolution quantitative imaging are mak...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2015.06.004

    authors: Saiz N,Plusa B,Hadjantonakis AK

    更新日期:2015-12-01 00:00:00

  • Sound perception in plants.

    abstract::Can plants perceive sound? And what sounds are they likely to be "listening" to? The environment of plants includes many informative sounds, produced by biotic and abiotic sources. An ability to respond to these sounds could thus have a significant adaptive value for plants. We suggest the term phytoacoustics to descr...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2019.03.006

    authors: Khait I,Obolski U,Yovel Y,Hadany L

    更新日期:2019-08-01 00:00:00

  • Evolution of "determinants" in sex-determination: a novel hypothesis for the origin of environmental contingencies in avian sex-bias.

    abstract::Sex-determination is commonly categorized as either "genetic" or "environmental"-a classification that obscures the origin of this dichotomy and the evolution of sex-determining factors. The current focus on static outcomes of sex-determination provides little insight into the dynamic developmental processes by which ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2008.11.013

    authors: Uller T,Badyaev AV

    更新日期:2009-05-01 00:00:00

  • Mitochondrial heteroplasmy beyond the oocyte bottleneck.

    abstract::Inheritance of the mitochondrial genome does not follow the rules of conventional Mendelian genetics. The mitochondrial DNA (mtDNA) is present in many copies per cell and is inherited through the maternal germline. In addition, mutations in the mtDNA will give rise to heteroplasmy, the coexistence of different mtDNA v...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2019.10.001

    authors: van den Ameele J,Li AYZ,Ma H,Chinnery PF

    更新日期:2020-01-01 00:00:00

  • Cholesterol homeostasis in neurons and glial cells.

    abstract::Cholesterol is highly enriched in the brain compared to other tissues. Essentially all cholesterol in the brain is synthesized endogenously since plasma lipoproteins are unable to cross the blood-brain barrier. Cholesterol is transported within the central nervous system in the form of apolipoprotein E-containing lipo...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2005.01.005

    authors: Vance JE,Hayashi H,Karten B

    更新日期:2005-04-01 00:00:00

  • How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays.

    abstract::Kinesins are enzymes that use the energy of ATP to perform mechanical work. There are approximately 14 families of kinesins within the kinesin superfamily. Family classification is derived primarily from alignments of the sequences of the core motor domain. For this reason, the enzymatic behavior and motility of each ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2010.01.018

    authors: Wordeman L

    更新日期:2010-05-01 00:00:00

  • Role of the immune system in regeneration and its dynamic interplay with adult stem cells.

    abstract::The immune system plays an indispensable role in the process of tissue regeneration following damage as well as during homeostasis. Inflammation and immune cell recruitment are signs of early onset injury. At the wound site, immune cells not only help to clear debris but also secrete numerous signalling molecules that...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2018.04.002

    authors: Abnave P,Ghigo E

    更新日期:2019-03-01 00:00:00

  • The nuclear transport machinery as a regulator of Drosophila development.

    abstract::The developmental processes that give rise to the animal body plan are exceedingly complex. Model systems such as Drosophila melanogaster have yielded profound insight into roles of conserved genes and genetic pathways in development. Drosophila development begins with the formation of sperm and eggs, and proceeds thr...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2009.02.006

    authors: Mason DA,Goldfarb DS

    更新日期:2009-07-01 00:00:00

  • Towards a genome-wide reconstruction of cis-regulatory networks in the human genome.

    abstract::The vast amount of recent progress made on the sequence of the human genome has allowed an unprecedented examination of cis-regulatory networks. These networks consist of functional elements such as promoters, enhancers, silencers, and insulators, and their coordinated activity is responsible for regulation of gene ex...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2009.06.005

    authors: Cecchini KR,Raja Banerjee A,Kim TH

    更新日期:2009-09-01 00:00:00

  • Coral biomineralization: A focus on intra-skeletal organic matrix and calcification.

    abstract::In the recent years several papers and some reviews have dealt with characterization, localization and influence on the precipitation of calcium carbonate, of the organic matrix from scleractinian corals. In fact, it has been well established that coral calcification is a biological controlled process orchestrated in ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2015.09.005

    authors: Falini G,Fermani S,Goffredo S

    更新日期:2015-10-01 00:00:00

  • Secrets from immortal worms: What can we learn about biological ageing from the planarian model system?

    abstract::Understanding how some animals are immortal and avoid the ageing process is important. We currently know very little about how they achieve this. Research with genetic model systems has revealed the existence of conserved genetic pathways and molecular processes that affect longevity. Most of these established model o...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2017.08.028

    authors: Sahu S,Dattani A,Aboobaker AA

    更新日期:2017-10-01 00:00:00

  • Regulation of blood vessel sprouting.

    abstract::Blood vessels are essential conduits of nutrients and oxygen throughout the body. The formation of these vessels involves angiogenic sprouting, a complex process entailing highly integrated cell behaviors and signaling pathways. In this review, we discuss how endothelial cells initiate a vessel sprout through interact...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2011.10.006

    authors: Chappell JC,Wiley DM,Bautch VL

    更新日期:2011-12-01 00:00:00

  • When timing is everything: role of cell cycle regulation in asymmetric division.

    abstract::Asymmetric division is a fundamental mechanism of generating cell diversity during development. One of its hallmarks is asymmetric localization during mitosis of proteins that specify daughter cell fate. Studies in Drosophila show that subcellular localization of many proteins required for asymmetric division of neuro...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2005.02.005

    authors: Prokopenko SN,Chia W

    更新日期:2005-06-01 00:00:00

  • The pharyngeal pouches and clefts: Development, evolution, structure and derivatives.

    abstract::The pharyngeal arches form the face and neck of the developing embryo. The pharyngeal tissue is divided into distinct arches by the formation of clefts and pouches in between the arches. These clefts and pouches form at the juxtaposition between the ectoderm and endoderm and develop into a variety of essential structu...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2010.01.022

    authors: Grevellec A,Tucker AS

    更新日期:2010-05-01 00:00:00

  • Tissue transplantation in planarians: A useful tool for molecular analysis of pattern formation.

    abstract::Freshwater planarians are well known for their remarkable plasticity and regenerative capabilities. Most studies of planarian regeneration have specifically examined regeneration after transverse or longitudinal sectioning or during homeostasis in intact adults. However, tissue transplantation, first performed over a ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2018.05.022

    authors: Rojo-Laguna JI,Garcia-Cabot S,Saló E

    更新日期:2019-03-01 00:00:00

  • The processing of yeast pheromones.

    abstract::Yeast provides an attractive system in which to study proprotein processing. Many of their processing events are remarkably similar to those in higher eukaryotes and their amenability to experimental manipulation permits approaches that are not always feasible in multicellular organisms. Analysing the biosynthesis of ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章

    doi:10.1006/scdb.1997.0197

    authors: Davey J,Davis K,Hughes M,Ladds G,Powner D

    更新日期:1998-02-01 00:00:00

  • Colour variation in cichlid fish: developmental mechanisms, selective pressures and evolutionary consequences.

    abstract::Cichlid fishes constitute one of the most species-rich families of vertebrates. In addition to complex social behaviour and morphological versatility, they are characterised by extensive diversity in colouration, both within and between species. Here, we review the cellular and molecular mechanisms underlying colour v...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2013.05.003

    authors: Maan ME,Sefc KM

    更新日期:2013-06-01 00:00:00

  • Planar cell polarity and vertebrate organogenesis.

    abstract::In addition to being polarized along their apical/basal axis, cells composing most (if not all) organs are also polarized in a plane vertical to the A/B axis. Recent studies indicate that this so-called planar cell polarity (PCP) plays an essential role in the formation of multiple organ systems regulating directed ce...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2006.05.003

    authors: Karner C,Wharton KA Jr,Carroll TJ

    更新日期:2006-04-01 00:00:00

  • EGFR signaling in breast cancer: bad to the bone.

    abstract::The epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptor tyrosine kinases. This family includes EGFR/ErbB1/HER1, ErbB2/HER2/Neu ErbB3/HER3, and ErbB4/HER4. For many years it was believed that EGFR plays a minor role in the development and progression of breast malignancies. However, recen...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2010.08.009

    authors: Foley J,Nickerson NK,Nam S,Allen KT,Gilmore JL,Nephew KP,Riese DJ 2nd

    更新日期:2010-12-01 00:00:00

  • Formation of the vertebrate embryo: Moving beyond the Spemann organizer.

    abstract::During the course of their classic experiments, Hilde Mangold and Hans Spemann discovered that the dorsal blastopore lip of an amphibian gastrula was able to induce formation of a complete embryonic axis when transplanted into the ventral side of a host gastrula embryo. Since then, the inducing activity of the dorsal ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2015.05.007

    authors: Thisse B,Thisse C

    更新日期:2015-06-01 00:00:00

  • Sizing it up: the mechanical feedback hypothesis of organ growth regulation.

    abstract::The question of how the physical dimensions of animal organs are specified has long fascinated both experimentalists and computational scientists working in the field of developmental biology. Research over the last few decades has identified many of the genes and signaling pathways involved in organizing the emergent...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2014.06.018

    authors: Buchmann A,Alber M,Zartman JJ

    更新日期:2014-11-01 00:00:00

  • Glyoxalase system in yeasts: structure, function, and physiology.

    abstract::The glyoxalase system consists of glyoxalase I and glyoxalase II. Glyoxalase I catalyzes the conversion of methylglyoxal (CH(3)COCHO), a metabolite derived from glycolysis, with glutathione to S-D-lactoylglutathione, while glyoxalase II hydrolyses this glutathione thiolester to D-lactic acid and glutathione. Since met...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2011.02.002

    authors: Inoue Y,Maeta K,Nomura W

    更新日期:2011-05-01 00:00:00

  • Perinatal inflammation and adult psychopathology: From preclinical models to humans.

    abstract::Perinatal environment plays a crucial role in brain development and determines its function through life. Epidemiological studies and clinical reports link perinatal exposure to infection and/or immune activation to various psychiatric disorders. In addition, accumulating evidence from animal models shows that perinat...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2017.09.010

    authors: Depino AM

    更新日期:2018-05-01 00:00:00

  • Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake.

    abstract::Extracellular vesicles (EVs), lipid bilayer-enclosed structures that contain a variety of biological molecules shed by cells, are increasingly becoming appreciated as a major form of cell-to-cell communication. Indeed, EVs have been shown to play important roles in several physiological processes, as well as diseases ...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2017.01.002

    authors: French KC,Antonyak MA,Cerione RA

    更新日期:2017-07-01 00:00:00

  • Nerves, H2O2 and Shh: Three players in the game of regeneration.

    abstract::The tight control of reactive oxygen species (ROS) levels is required during regeneration. H2O2 in particular assumes clear signalling functions at different steps in this process. Injured nerves induce high levels of H2O2 through the activation of the Hedgehog (Shh) pathway, providing an environment that promotes cel...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2017.08.015

    authors: Meda F,Rampon C,Dupont E,Gauron C,Mourton A,Queguiner I,Thauvin M,Volovitch M,Joliot A,Vriz S

    更新日期:2018-08-01 00:00:00

  • The role of the EGFR signaling pathway in stem cell differentiation during planarian regeneration and homeostasis.

    abstract::Cell signaling is essential for cells to adequately respond to their environment. One of the most evolutionarily conserved signaling pathways is that of the epidermal growth factor receptor (EGFR). Transmembrane receptors with intracellular tyrosine kinase activity are activated by the binding of their corresponding l...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2018.05.011

    authors: Barberán S,Cebrià F

    更新日期:2019-03-01 00:00:00

  • Lipid profiling of brain tissue and blood after traumatic brain injury: A review of human and experimental studies.

    abstract::Traumatic brain injury (TBI) is a neurological condition which affects a large number of individuals worldwide, across all ages. It can lead to major physical, cognitive and psychological impairment, and represents a considerable health cost burden. TBI is a heterogeneous condition and there has been intense effort ov...

    journal_title:Seminars in cell & developmental biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.semcdb.2020.08.004

    authors: Nessel I,Michael-Titus AT

    更新日期:2020-10-06 00:00:00