Abstract：
:The intermediate mesoderm is located between the somites and the lateral plate mesoderm and gives rise to renal progenitors that contribute to the three mammalian kidney types (pronephros, mesonephros and metanephros). In this review, focusing largely on murine kidney development, we examine how the intermediate mesoderm forms during gastrulation/axis elongation and how it progressively gives rise to distinct renal progenitors along the rostro-caudal axis. We highlight some of the potential signalling cues and core transcription factor circuits that direct these processes, up to the point of early metanephric kidney formation.
journal_name
Semin Cell Dev Bioljournal_title
Seminars in cell & developmental biologyauthors
Davidson AJ,Lewis P,Przepiorski A,Sander Vdoi
10.1016/j.semcdb.2018.08.016subject
Has Abstractpub_date
2019-07-01 00:00:00pages
86-93eissn
1084-9521issn
1096-3634pii
S1084-9521(17)30417-2journal_volume
91pub_type
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journal_title：Seminars in cell & developmental biology
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journal_title：Seminars in cell & developmental biology
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