Cloning and characterization of a novel human gene RNF38 encoding a conserved putative protein with a RING finger domain.

abstract：:One hypothesis for the etiology of Parkinson's disease (PD) is that the formation of proteinaceous inclusion, which is mainly composed of alpha-synuclein, may contribute to the selective loss of dopaminergic neurons. To further explore the role of alpha-synuclein in neurodegeneration of PD, we examined the possible ef...

journal_title：Biochemical and biophysical research communications

authors： Yu F,Xu H,Zhuo M,Sun L,Dong A,Liu X

更新日期：2005-05-27 00:00:00

abstract：:Transforming growth factor beta 1 (TGF beta 1) has been reported to be secreted and to act within the somatic cells of the testis. We examined whether the TGF beta 1 expression is present at mRNA and protein levels in purified rat Sertoli cells (SC), purified pachytene spermatocytes (SPC), and early spermatids (SPT) c...

journal_title：Biochemical and biophysical research communications

authors： Avallet O,Gomez E,Vigier M,Jégou B,Saez JM

更新日期：1997-09-29 00:00:00

abstract：:Standardized RT-PCR (StaRT-PCR) enables numerical quantification as well as intra- and inter-laboratory comparison of gene expression. Multiplex StaRT-PCR, using two rounds of amplification, was conducted on Stratagene Universal Reference RNA. In the first round, cDNA, competitive template (CT) mix, and primers for up...

journal_title：Biochemical and biophysical research communications

authors： Crawford EL,Warner KA,Khuder SA,Zahorchak RJ,Willey JC

更新日期：2002-04-26 00:00:00

abstract：:Internal and environmental cues, including ambient temperature changes, regulate the timing of flowering in plants. Arabidopsis miR156 represses flowering and plays an important role in the regulation of temperature-responsive flowering. However, the molecular basis of miR156 processing at lower temperatures remains l...

journal_title：Biochemical and biophysical research communications

authors： Kim HE,Kim W,Lee AR,Jin S,Jun AR,Kim NK,Lee JH,Ahn JH

更新日期：2017-03-18 00:00:00

abstract：:In mammalian cells, the Rab7 protein is a key element of late endocytic membrane traffic. Several results suggest that it is involved in the transport from early to late endosome or from late endosome to lysosome. We have previously characterized a Rab7 gene homologue (TcRAB7) in Trypanosoma cruzi. Now, using an affin...

journal_title：Biochemical and biophysical research communications

authors： Araripe JR,Cunha e Silva NL,Leal ST,de Souza W,Rondinelli E

更新日期：2004-08-20 00:00:00

abstract：:High expression of Rad51, the catalytic component in homologous recombination, has been reported to contribute to genomic instability. To elucidate biological processes related to Rad51, we performed global gene expression analysis on human fibrosarcoma cells induced to express variable Rad51 levels. The results indic...

journal_title：Biochemical and biophysical research communications

authors： Orre LM,Fält S,Szeles A,Lewensohn R,Wennborg A,Flygare J

更新日期：2006-03-10 00:00:00

abstract：:Zinc is an essential element for the biological system. However, excessive exogenous Zn2+ would disrupt cellular Zn2+ homeostasis and cause toxicity. In particular, Zinc salts or ZnO nanoparticles exposure could induce respiratory injury. Although previous studies have indicated that organelle damage (including mitoch...

journal_title：Biochemical and biophysical research communications

authors： Qin X,Zhang J,Wang B,Xu G,Zou Z

更新日期：2017-06-17 00:00:00

abstract：:To assess laser modulation of wound healing, full-thickness cutaneous wounds were produced in the backs of pigs, and subjected to treatment with helium-neon laser. For comparison, some wounds were treated with non-laser energy source (a tungsten light) or left untreated as controls. Type I and type III procollagen mRN...

journal_title：Biochemical and biophysical research communications

authors： Saperia D,Glassberg E,Lyons RF,Abergel RP,Baneux P,Castel JC,Dwyer RM,Uitto J

更新日期：1986-08-14 00:00:00

abstract：:Ornithine decarboxylase (ODC) was induced in the liver, lung and brain of the mouse injected intraperitoneally with 12-O-tetradecanoylphorbol 13-acetate (TPA), showing maximal enzyme activity four hours after the injection. The increase of ODC activity was due to the enhanced syntheses of mRNA and protein. The inducti...

journal_title：Biochemical and biophysical research communications

authors： Hibasami H,Tsukada T,Maekawa S,Sakurai M,Nakashima K

更新日期：1987-04-29 00:00:00

abstract：:ATP binding cassette (ABC) transporters have a functional unit formed by two transmembrane domains and two nucleotide binding domains (NBDs). ATP-bound NBDs dimerize in a head-to-tail arrangement, with two nucleotides sandwiched at the dimer interface. Both NBDs contribute residues to each of the two nucleotide-bindin...

journal_title：Biochemical and biophysical research communications

authors： Zoghbi ME,Altenberg GA

更新日期：2014-01-03 00:00:00

abstract：:The ATPase activity of F1 isolated from the thermophilic bacterium PS3 is stimulated at 30 degrees C by the anionic detergents cholate or deoxycholate. Maximal activity obtained with these detergents (35 mumol/min X mg) is similar to the activity reported for the optimal temperature, 75 degrees C. The activity is line...

journal_title：Biochemical and biophysical research communications

authors： Norling B

更新日期：1986-05-14 00:00:00

abstract：:The cytoplasmic domain of the neural cell adhesion molecule (NCAM) contains multiple phosphorylation sites. We report here that in addition to serine and threonine residues a tyrosine of the NCAM180 isoform is phosphorylated as shown by phosphoamino acid analysis. Exchange of the only cytoplasmic tyrosine at position ...

journal_title：Biochemical and biophysical research communications

authors： Diestel S,Laurini C,Traub O,Schmitz B

更新日期：2004-09-10 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is a mitogen that is critically involved in vasculogenesis, angiogenesis, and hematopoiesis. However, what and how transcription factors participate in the regulation of vegf gene expression are not fully understood. Here we report the cloning and sequencing of the zebrafish v...

journal_title：Biochemical and biophysical research communications

authors： He C,Chen X

更新日期：2005-04-01 00:00:00

abstract：:In inflammatory cells, intracellular cAMP concentration is regulated by cyclic nucleotide phosphodiesterases 4. Therefore, PDE4 inhibition appears as a rational goal for treating acute or chronic inflammatory diseases. Selective PDE4 inhibitors have been developed, but due to unwanted side effects, search for new sele...

journal_title：Biochemical and biophysical research communications

authors： Reimund JM,Raboisson P,Pinna G,Lugnier C,Bourguignon JJ,Muller CD

更新日期：2001-10-26 00:00:00

abstract：:Resveratrol (3,5,4'-trihydroxystilbene) is a naturally occurring phytoalexin, found in grapes and wine, which has been reported to exert a variety of important pharmacological effects. We have investigated the activity of resveratrol on proliferation and differentiation of the promyelocitic cell line HL-60. A concentr...

journal_title：Biochemical and biophysical research communications

authors： Ragione FD,Cucciolla V,Borriello A,Pietra VD,Racioppi L,Soldati G,Manna C,Galletti P,Zappia V

更新日期：1998-09-08 00:00:00

abstract：:Dickkopf-1 (DKK-1) is known inhibitor of the canonical Wnt pathway. Recent studies strongly suggested that activation of DKK-1 expression results in inhibition of cell tumorigenicity. Reduced levels of DKK-1 in melanomas were recently shown. However, it is not known if DKK-1 activation in melanoma cells will inhibit c...

journal_title：Biochemical and biophysical research communications

authors： Mikheev AM,Mikheeva SA,Rostomily R,Zarbl H

更新日期：2007-01-19 00:00:00

abstract：:The S. cerevisiae a-factor, YIIKGVFWDPAC(s-farnesyl)-OCH3, is one of two peptide mating pheromones which mediate cell-cell communication in S. cerevisiae. We previously reported that replacing Gly5 with D-Ala led to a 4-6 fold increase in activity while the L-Ala5 homolog was 4 to 16-fold less active than the wildtype...

journal_title：Biochemical and biophysical research communications

authors： Zhang YL,Dawe AL,Jiang Y,Becker JM,Naider F

更新日期：1996-07-16 00:00:00

abstract：:The short-term incubation of HeLa cells in the presence of diferric transferrin or ferricyanide, which are reduced externally by the transplasma membrane reductase, produces a stoichiometric decrease in NADH and increase in NAD+, which is stimulated by insulin. The NADP/NADPH ratio does not change during 15 min incuba...

journal_title：Biochemical and biophysical research communications

authors： Navas P,Sun IL,Morré DJ,Crane FL

更新日期：1986-02-26 00:00:00

abstract：:Comparison between gel electrophoresis migrations of oligo-alpha-thymidylates and oligo-beta-thymidylates indicates that the migration of alpha-oligonucleotides under native conditions is different from the migration of beta-oligonucleotides when the number of thymines, part of the sequence, is higher than 5. Such dif...

journal_title：Biochemical and biophysical research communications

authors： Bertrand JR,Bazile D,Malvy C,Paoletti J

更新日期：1990-01-15 00:00:00

abstract：:Aggregation of proteins is a frequent occurrence during their transition from random coil to native structure. The influence of cyclodextrins in the refolding of carbonic anhydrase under aggregating conditions was studied. Cyclodextrin prevented formation of protein aggregates during renaturation of carbonic anhydrase...

journal_title：Biochemical and biophysical research communications

authors： Karuppiah N,Sharma A

更新日期：1995-06-06 00:00:00

abstract：:Transgenic (TG) mice expressing porcine GH receptor (pGHR) directed by a 762-bp proximal leptin promoter were used to analyze the capability of the promoter to drive and regulate pGHR expression in vivo. Transgene expression occurred in inguinal, retroperitoneal, and epididymal/parametrial fat depots in both male and ...

journal_title：Biochemical and biophysical research communications

authors： Chen XL,Hartzell DL,McGraw RA,Hausman GJ,Dean RG

更新日期：1999-08-19 00:00:00

abstract：:Cyclin B is a ubiquitous regulatory molecule and has been implicated in mitosis and meiosis in oocytes. Phenomenon that differ in the length of cyclin B 3'UTR in crustacean has attracted much attention, although molecular details are poorly understood. The study of 3'UTR-interacting proteins could yield much informati...

journal_title：Biochemical and biophysical research communications

authors： Shui Y,Liu GF,Xu ZH,Zhu GY

更新日期：2019-09-24 00:00:00

abstract：:The phthalate ester insensitive blue-green algae (Synechococcus lividus) were used as a food source to extend the survival of synchronously hatched brine shrimp (Artemia salina) larvae allowing measurement of a reduced toxic response to phthalate esters at late post-hatching stages of development. The maximum acute to...

journal_title：Biochemical and biophysical research communications

authors： Acey RA,Bailey S,Healy P,Jo C,Unger TF,Hudson RA

更新日期：2002-12-13 00:00:00

abstract：BACKGROUND:Adiponectin (APN) is an adipocyte-derived bioactive molecule with anti-diabetic and anti-atherogenic properties. Although anti-diabetic effects are mostly mediated by the adiponectin receptors AdipoR1 and AdipoR2, the anti-atherogenic mechanisms have not been fully elucidated. METHODS AND RESULTS:In this st...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto H,Kuroda N,Uekita H,Kochi I,Matsumoto A,Niinaga R,Funahashi T,Shimomura I,Kihara S

更新日期：2016-02-05 00:00:00

abstract：:Hepatocytes isolated from normal adult rats were maintained at sub-confluent density in a defined medium in primary culture. In control cultures with added epidermal growth factor and low concentrations of dexamethasone, the rate of DNA synthesis was initially low but increased after about 30 hours in culture. Additio...

journal_title：Biochemical and biophysical research communications

authors： Edwards AM,Lucas CM

更新日期：1985-08-30 00:00:00

abstract：:Oxytocin binding activity of myoepithelial cell membranes from mammary tissue was measured under a variety of different experimental conditions. Mammary tissue from non-lactating rats bound oxytocin with a Kd of 9.2 +/- 1.6 nM (+/- S.E.) and indicates that receptors are retained by the myoepithelial cells in a non-lac...

journal_title：Biochemical and biophysical research communications

authors： Ruberti A,Olins GM,Eakle KA,Bremel RD

更新日期：1983-04-29 00:00:00

abstract：:C3 is common to all pathways of complement activation augmenting ischemia/reperfusion (I/R)-induced myocardial injury and cardiac dysfunction. Complement inhibition with the complement regulatory protein, C1 inhibitor (C1INH), obviously exerts cardioprotective effects. Here, we examine whether C1INH regulates C3 activ...

journal_title：Biochemical and biophysical research communications

authors： Fu J,Lin G,Zeng B,Wu Z,Wu Y,Chu H,Qin G,Liang G,Li J,Gan X,Yu X,Li C,Liu D

更新日期：2006-11-10 00:00:00

abstract：:The study of [3H]-uridine uptake by mouse peritoneal macrophages showed that this is an active, temperature- and protein synthesis-dependent phenomenon, which is early altered when are exposed to a variety of stimuli. Murine recombinant interferon-gamma, a stimulus able to activate macrophage and to induce the product...

journal_title：Biochemical and biophysical research communications

authors： Busolo F,Conventi L,Gatti C,Monti D,Troiano L,Franceschi C

更新日期：1989-04-14 00:00:00

abstract：:A high yielding fusion protein system based on the protein cytochrome b(5) has been used for the production of novel 13-residue acyclic conopeptide. This peptide, Mo1659, can be liberated from the carrier protein using CNBr cleavage and subsequent purification using RP-HPLC methods. The yield of isotopically enriched ...

journal_title：Biochemical and biophysical research communications

authors： Kumar GS,Ramasamy P,Sikdar SK,Sarma SP

更新日期：2005-09-30 00:00:00

abstract：:Pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder characterized by hypertension, hyperkalemia, and hyperchloremic acidosis, is reportedly due to mutations in WNK1 and WNK4 kinase genes. However, the pathogenesis of the disease remains unknown. Mutations in the WNK1 gene are the deletions in the f...

journal_title：Biochemical and biophysical research communications

authors： Ohta A,Yang SS,Rai T,Chiga M,Sasaki S,Uchida S

更新日期：2006-10-20 00:00:00