Abstract:
:Comparison between gel electrophoresis migrations of oligo-alpha-thymidylates and oligo-beta-thymidylates indicates that the migration of alpha-oligonucleotides under native conditions is different from the migration of beta-oligonucleotides when the number of thymines, part of the sequence, is higher than 5. Such difference disappears when the gels are run under denaturing conditions. This, together with UV spectra, indicates that the structure of alpha-oligonucleotides is more organized than the structure of beta-oligonucleotides and that such an organisation appears for a length higher than 5 monomeric units.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Bertrand JR,Bazile D,Malvy C,Paoletti Jdoi
10.1016/0006-291x(90)91944-nsubject
Has Abstractpub_date
1990-01-15 00:00:00pages
293-8issue
1eissn
0006-291Xissn
1090-2104pii
0006-291X(90)91944-Njournal_volume
166pub_type
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