Bronchiolitis obliterans organizing pneumonia in a patient with chronic myelogenous leukemia developing after initiation of interferon and cytosine arabinoside.

abstract：:Little is known about the S100B⁺ lymphocytes, which are unique human peripheral blood lymphocytes (PBL) containing the S100B protein. It has recently been shown that S100B is released from various types of S100B⁺ cells and exhibits varied cytokine-like activities. In this study, we precisely characterized the S100B⁺ l...

journal_title：European journal of haematology

authors： Miki Y,Gion Y,Mukae Y,Hayashi A,Sato H,Yoshino T,Takahashi K

更新日期：2013-02-01 00:00:00

abstract：:In recent years, several direct-acting oral anticoagulants (DOAC) have become available for use in Europe and other regions in indications related to prophylaxis and treatment of venous and arterial thromboembolism. They include the oral direct thrombin inhibitor dabigatran etexilate (Pradaxa, Boehringer Ingelheim) an...

journal_title：European journal of haematology

authors： Gómez-Outes A,Suárez-Gea ML,Lecumberri R,Terleira-Fernández AI,Vargas-Castrillón E

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:From 1954 to 1987, flour in Denmark was fortified with 30 mg carbonyl iron per kg. This mandatory fortification was abolished in 1987. The aim of this study was to compare iron status in Danish men before and after abolition of iron fortification. METHODS:Iron status (serum ferritin, haemoglo...

journal_title：European journal of haematology

authors： Milman N,Byg KE,Ovesen L,Kirchhoff M,Jürgensen KS

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:To investigate whether the glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab (GA101) combined with the selective MDM2 antagonist idasanutlin (RG7388) offers superior efficacy to monotherapy in treating B-lymphoid malignancies in preclinical models. METHODS:The combined effect of obinutuzuma...

journal_title：European journal of haematology

authors： Herting F,Herter S,Friess T,Muth G,Bacac M,Sulcova J,Umana P,Dangl M,Klein C

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Northern Norway consists of a multiethnic population of Sámi and non-Sámi. We evaluated iron status in these two groups with respect to gender, age and residence. METHODS:In 2002-2004, a cross-sectional study of health and living conditions in areas with both Sámi and Norwegian populations, SAMINOR, was per...

journal_title：European journal of haematology

authors： Broderstad AR,Melhus M,Lund E

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine the impact of socioeconomic status on relapse-free survival (RFS) in patients with Hodgkin's disease. METHODS:A number of factors were analyzed for their impact on relapse-free and overall survival in Hodgkin's disease using Cox regression. These factors included socioe...

journal_title：European journal of haematology

authors： Holzner B,Fischhofer M,Kemmler G,Kopp M,Sperner-Unterweger B,Krugmann J,Dirnhofer S,Greil R

更新日期：2004-11-01 00:00:00

abstract：:15 cases of acute leukemia (AL) displaying a TdT+, HLA-DR+ phenotype were studied; surface immunoglobulins, T cell markers and the common acute lymphoblastic leukaemia (c-ALL) antigen were negative, as were peroxidase and non-specific esterase cytochemical reactions. All cases were extensively investigated by conventi...

journal_title：European journal of haematology

authors： Basso G,Putti MC,Catoretti G,Consolini R,Galdiolo D,Guglielmi C,Messina C,Milanesi C,Testi AM,Xillo MZ

更新日期：1987-02-01 00:00:00

abstract：:We describe a case of Philadelphia-positive chronic myeloid leukaemia occurring simultaneously with B-cell chronic lymphocytic leukaemia in a 69-yr-old male. Gene probe analysis of DNA from both peripheral blood and bone marrow provided evidence for the independent evolution of 2 clones in this case, with a predominan...

journal_title：European journal of haematology

authors： Browett PJ,Pattinson J,Pinkney J,Hoffbrand AV,Norton JD

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVES:Recent studies have indicated that patients who receive stem cell transplantation (SCT) and rituximab demonstrate an increased risk of developing hypogammaglobulinemia. Such hypogammaglobulinemia has been found to be due to delayed recovery of memory B cells with an abnormal cell marker expression and impair...

journal_title：European journal of haematology

authors： Nishio M,Endo T,Fujimoto K,Yamamoto S,Obara M,Yamaguchi K,Takeda Y,Goto H,Kasahara I,Sato N,Koike T

更新日期：2009-02-01 00:00:00

abstract：:No consecutive analysis of BAALC and WT1 expressions associated with core-binding factor AML (CBF-AML) from diagnosis to hematopoietic stem cell transplantation (HSCT) has yet been reported. We investigated BAALC and WT1 expressions using a method of real-time quantitative polymerase chain reaction (RQ-PCR) at diagnos...

journal_title：European journal of haematology

authors： Yoon JH,Kim HJ,Shin SH,Yahng SA,Lee SE,Cho BS,Eom KS,Kim YJ,Lee S,Min CK,Cho SG,Kim DW,Lee JW,Min WS,Park CW,Lim JH

更新日期：2013-08-01 00:00:00

abstract：:The presence of CD25 and HC2 antigens in 66 different patients with acute myeloid leukemia (AML) was investigated. The expression of both antigens was observed in 32% of AML cells. Dual fluorescence staining experiments performed in 5 AML patient cells showed that CD25 and HC2 antigens were simultaneously expressed in...

journal_title：European journal of haematology

authors： Padrós MR,Salamone MC,Zunszain PA,Fainboim L

更新日期：1989-05-01 00:00:00

abstract：:Beta-thalassaemia is characterised by progressive anaemia necessitating regular blood transfusions to sustain life. With the advent of effective chelating agents that can reduce the iron burden and extend patients' survival, renal disease, as in other ageing populations, has become more prevalent. In recent years, chr...

journal_title：European journal of haematology

authors： Bhandari S,Galanello R

更新日期：2012-09-01 00:00:00

abstract：:While cellular modulation in vitro of committed hematopoietic stem cell (HSC) growth has been known for some time, less is known about the effect of accessory cells (AC) on the growth of more immature HSC. We have examined the effect of peripheral blood (PB) AC on hematopoiesis by coculturing enriched PB CD34+ cells (...

journal_title：European journal of haematology

authors： Olesen G,Tønder H,Palshof T,Hokland P

更新日期：2002-02-01 00:00:00

abstract：:Several studies have reported data on factors influencing mobilization of peripheral blood stem cells (PBSC) in non-myeloid malignancies. On the contrary, data from patients with acute myeloid leukemia (AML) are very limited, in particular, as the impact of an antecedent diagnosis of refractory anemia with excess blas...

journal_title：European journal of haematology

authors： Viola A,Falco C,D'Elia R,D'Amico MR,Vicari L,Tambaro FP,Correale P,Laudati D,Palmieri S,Ferrara F

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Although there are two major scoring systems for the clinical diagnosis of disseminated intravascular coagulation (DIC), the validity of these systems for leukemia-associated DIC remains to be confirmed. METHODS:By analyzing 125 newly diagnosed acute leukemia patients, we investigated clinical and laborator...

journal_title：European journal of haematology

authors： Yanada M,Matsushita T,Suzuki M,Kiyoi H,Yamamoto K,Kinoshita T,Kojima T,Saito H,Naoe T

更新日期：2006-10-01 00:00:00

abstract：:Oxidative damage to erythrocytes in thalassaemia has been related to generation of free radicals by an excess of denaturated alpha- or beta-globin chains, intracellular iron overload and low concentration of normal haemoglobin (HGB). Two good indicators of such oxidative damage are the high red blood cell (RBC) malony...

journal_title：European journal of haematology

authors： Vives Corrons JL,Miguel-García A,Pujades MA,Miguel-Sosa A,Cambiazzo S,Linares M,Dibarrart MT,Calvo MA

更新日期：1995-11-01 00:00:00

abstract：:Myeloproliferative neoplasms associated with FIP1L1-PDGFR rearrangements represent a rare subset of myeloid and lymphoid malignancies, characterised by the presence of eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1 genes. The fusion product of such genes is a tyrosine kinase oncoprotein sensitive to imatini...

journal_title：European journal of haematology

authors： Barraco D,Carobolante F,Candoni A,Simeone E,Piccaluga P,Tabanelli V,Fanin R

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies. Unlike cytotoxic chemotherapy, drugs such as nivolumab, pembrolizumab, and ipilimumab are associated with immune-related adverse effects. We recent...

journal_title：European journal of haematology

authors： Tanios GE,Doley PB,Munker R

更新日期：2019-02-01 00:00:00

abstract：:In acute myeloid leukemia (AML) mouse models, the RUNX1-RUNX1T1 fusion protein has failed to produce leukemia by itself, but alternative splicing of exon 9a of the RUNX1-RUNX1T1 fusion transcript (FT) has recently been shown to enhance the leukemogenic potential. We have analyzed 138 diagnosis and follow-up samples fr...

journal_title：European journal of haematology

authors： Ommen HB,Ostergaard M,Yan M,Braendstrup K,Zhang DE,Hokland P

更新日期：2010-02-01 00:00:00

abstract：:We evaluated the utility of an immunocytochemical technique employing the commercially available anti-CD56 monoclonal antibody, NKH 1. The utility and sensitivity of this technique in the detection of invasive neuroblastoma (NB) cells in the bone marrow were compared with those of Wright-Giemsa staining. The correlati...

journal_title：European journal of haematology

authors： Nagai J,Kigasawa H,Tomioka K,Koga N,Nishihira H,Nagao T

更新日期：1994-08-01 00:00:00

abstract：:In the study of patients with Hodgkin's lymphoma (HL) the evaluation of bone marrow biopsy (BMB) can be difficult. In this review we analyze the main diagnostic features and the clinical risk factors of BM involvement. Although the role of BMB is criticized by some authors, its value is irreplaceable in the staging of...

journal_title：European journal of haematology

authors： Franco V,Tripodo C,Rizzo A,Stella M,Florena AM

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Most results on the treatment of chronic myeloid leukaemia (CML) with imatinib were obtained from clinical trials that may differ from the routine practice. We report the results of treatment of consecutive patients with CML at ten major centres during 2000-2008. PATIENTS AND METHODS:Data reporting was retr...

journal_title：European journal of haematology

authors： Faber E,Mužík J,Koza V,Demečková E,Voglová J,Demitrovičová L,Chudej J,Markuljak I,Cmunt E,Kozák T,Tóthová E,Jarošová M,Dušek L,Indrák K

更新日期：2011-08-01 00:00:00

abstract：:Alkaline phosphatase (ALP) activity of 70 cases of non-Hodgkin's lymphomas of the B-cell type was studied. ALP activity was found in malignant lymphoma (ML), follicular, small cleaved cell (1/5 cases); ML, diffuse, small cleaved cell (3/13 cases); and mantle zone lymphoma (intermediate lymphocytic lymphoma) (2/2 cases...

journal_title：European journal of haematology

authors： Abe M,Nozawa Y,Wachi E,Tominaga K,Hojo H,Wakasa H

更新日期：1988-09-01 00:00:00

abstract：:Cells from 3 patients with B-chronic lymphocytic leukaemia (B-CLL) and 1 with B-prolymphocytic leukaemia (B-PLL) were treated in vitro with the phorbol ester 12-0-tetradecanoylphorbol (TPA), the calcium ionophore A23187, or a combination of TPA and A23187. TPA induced the cells to adhere to the culture flask or to clu...

journal_title：European journal of haematology

authors： Drexler HG,Brenner MK,Gignac SM,Hoffbrand AV

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the activation of clotting systems in patients with sickle cell disease (SCD) by measuring the plasma D-dimer level and to determine the effect of low-dose warfarin on D-dimer level during vaso-occlusive crisis. METHODS:Plasma D-dimer level was measured in 65 blood samples of 37 adult patients wi...

journal_title：European journal of haematology

authors： Ahmed S,Siddiqui AK,Iqbal U,Sison CP,Shahid RK,Sheth M,Patel DV,Russo LA

更新日期：2004-03-01 00:00:00

abstract：:A patient with acute myelomonocytic leukaemia (M4 subtype) with pericentric inversion of chromosome 16, inv(16)(p13q22), and a marked basophilia is described. Results from transmission electron microscopy suggested that the basophils were immature. Clinically, although leukaemic cells had a tendency to infiltrate a nu...

journal_title：European journal of haematology

authors： Matsuura Y,Sato N,Kimura F,Shimomura S,Yamamoto K,Enomoto Y,Takatani O

更新日期：1987-11-01 00:00:00

abstract：:Acute myeloid leukaemia (AML) is an uncommon complication of patients with essential thrombocythaemia (ET). We report a patient with ET which progressed into AML and who had only received a few days of therapy with hydroxyurea (HU) when diagnosed with ET. This is extremely rare, as in large series no patients who were...

journal_title：European journal of haematology

authors： Bolaños-Meade J,López-Arvizu C,Cobos E

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:This study aims to characterize the epidemiology of immunocompetent Primary central nervous system lymphoma (PCNSL) diagnosed 2000-2013 in Sweden. METHODS:Cases were identified in the population-based Swedish Lymphoma Register. Incidence per 100 000 person-years and 95% confidence intervals (CI) were calcul...

journal_title：European journal of haematology

authors： Eloranta S,Brånvall E,Celsing F,Papworth K,Ljungqvist M,Enblad G,Ekström-Smedby K

更新日期：2018-01-01 00:00:00

abstract：:Few risk factors have been established for the plasma cell disorder multiple myeloma, but some of these like African American ethnicity and a family history of B-cell lymphoproliferative diseases suggest a genetic component for the disease. Genetic variation represents the genetic basis of variability in a population....

journal_title：European journal of haematology

authors： Vangsted A,Klausen TW,Vogel U

更新日期：2012-01-01 00:00:00

abstract：:Kostmann syndrome (KS) is an inherited hematological disorder characterized by an absolute neutrophil count (ANC) <0.2 x 109/L and life-threatening bacterial infections. Granulocyte-colony stimulating factor (G-CSF) makes it possible to reach an ANC of 1.0 x 109/L and consequently to reduce significantly the occurrenc...

journal_title：European journal of haematology

authors： Dallorso S,Manzitti C,Dodero P,Faraci M,Rosanda C,Castagnola E

更新日期：2003-05-01 00:00:00