当前位置： SCI文献检索 > EUROPEAN JOURNAL OF HAEMATOLOGY期刊下所有文献 > Increasing incidence of primary central nervous system lymphoma but no improvement in survival in Sweden 2000-2013.

Increasing incidence of primary central nervous system lymphoma but no improvement in survival in Sweden 2000-2013.

Abstract：

OBJECTIVES:This study aims to characterize the epidemiology of immunocompetent Primary central nervous system lymphoma (PCNSL) diagnosed 2000-2013 in Sweden. METHODS:Cases were identified in the population-based Swedish Lymphoma Register. Incidence per 100 000 person-years and 95% confidence intervals (CI) were calculated, and PCNSL-specific survival was estimated using relative survival. Tests for temporal trends were performed using Poisson regression. Population incidence of all brain tumors was retrieved for comparison. RESULTS:With 359 identified PCNSL cases (median age 66 years), overall incidence was 0.26 (95% CI: 0.24-0.29) and the average annual increase 4% (P = .002). The increasing trend was primarily observed among elderly individuals (70+ years). Similarly, an increase in incidence of all brain tumors was noted only among the elderly. There was no significant improvement in relative survival across the study period although, among fit patients (with Eastern Cooperative Oncology Group, EGOC 0), survival plateaued 6 years after diagnosis. CONCLUSION:The increasing PCNSL incidence in the elderly was consistent with an increasing incidence of brain tumors of any type and may in part be attributable to improved diagnostics and reporting in this group. New treatment options have not yet translated into general survival improvements in a population-based setting, although the presence of long-term survivors among fit patients is encouraging.

journal_name

Eur J Haematol

journal_title

European journal of haematology

authors

Eloranta S,Brånvall E,Celsing F,Papworth K,Ljungqvist M,Enblad G,Ekström-Smedby K

doi

10.1111/ejh.12980

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

61-68

issue

1

eissn

0902-4441

issn

1600-0609

journal_volume

100

pub_type

历史文章,杂志文章

相关文献

EUROPEAN JOURNAL OF HAEMATOLOGY文献大全
  • The prognostic significance of cytogenetic aberrations in childhood acute myeloid leukaemia. A study of the Swiss Paediatric Oncology Group (SPOG).

    abstract：:In childhood-onset acute myeloid leukaemia (AML) the clinical value of karyotypic aberrations is now acknowledged, although there is still debate concerning the prognostic significance of some events. To add to this knowledge, cytogenetic analysis was performed on a consecutive series of 84 childhood AML patients diag...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2007.00854.x

    authors： Betts DR,Ammann RA,Hirt A,Hengartner H,Beck-Popovic M,Kuhne T,Nobile L,Caflisch U,Wacker P,Niggli FK

    更新日期：2007-06-01 00:00:00

  • High level of full-length cereblon mRNA in lower risk myelodysplastic syndrome with isolated 5q deletion is implicated in the efficacy of lenalidomide.

    abstract：:Downregulation of cereblon (CRBN) gene expression is associated with resistance to the immunomodulatory drug lenalidomide and poor survival outcomes in multiple myeloma (MM) patients. However, the importance of CRBN gene expression in patients with myelodysplastic syndrome (MDS) and its impact on lenalidomide therapy ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12457

    authors： Jonasova A,Bokorova R,Polak J,Vostry M,Kostecka A,Hajkova H,Neuwirtova R,Siskova M,Sponerova D,Cermak J,Mikulenkova D,Cervinek L,Brezinova J,Michalova K,Fuchs O

    更新日期：2015-07-01 00:00:00

  • Increased susceptibility of microcytic red blood cells to in vitro oxidative stress.

    abstract：:Oxidative damage to erythrocytes in thalassaemia has been related to generation of free radicals by an excess of denaturated alpha- or beta-globin chains, intracellular iron overload and low concentration of normal haemoglobin (HGB). Two good indicators of such oxidative damage are the high red blood cell (RBC) malony...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1995.tb00705.x

    authors： Vives Corrons JL,Miguel-García A,Pujades MA,Miguel-Sosa A,Cambiazzo S,Linares M,Dibarrart MT,Calvo MA

    更新日期：1995-11-01 00:00:00

  • An increase in basophils in a case of acute myelomonocytic leukaemia associated with marrow eosinophilia and inversion of chromosome 16.

    abstract：:A patient with acute myelomonocytic leukaemia (M4 subtype) with pericentric inversion of chromosome 16, inv(16)(p13q22), and a marked basophilia is described. Results from transmission electron microscopy suggested that the basophils were immature. Clinically, although leukaemic cells had a tendency to infiltrate a nu...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1987.tb01456.x

    authors： Matsuura Y,Sato N,Kimura F,Shimomura S,Yamamoto K,Enomoto Y,Takatani O

    更新日期：1987-11-01 00:00:00

  • High-dose cyclophosphamide, etoposide and BCNU (CVB) with autologous stem cell rescue in malignant lymphomas.

    abstract：:Eighteen patients with malignant lymphoma, 10 non-Hodgkin's and 8 Hodgkin's, were treated with high-dose CVB (cyclophosphamide 4 x 1.5 g/m2, etoposide 4 x 250-400 mg/m2, carmustine 4 x 150-200 mg/m2), followed by autologous peripheral blood stem cells (PBSC, 13 patients) or bone marrow (BM, 5 patients) transplantation...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1993.tb00599.x

    authors： Patti C,Majolino I,Scimè R,Indovina A,Vasta S,Liberti G,Gentile S,Santoro A,Pisa R,Caronia F

    更新日期：1993-07-01 00:00:00

  • Use of splenic volume estimation to distinguish primary thrombocythaemia from reactive thrombocytosis.

    abstract：:Splenic volume was measured by visual assessment of planar images of the spleen, and also by single photon emission computerised tomography (SPECT) using 99mtechnetium tin colloid, in a group of 33 patients with primary thrombocythaemia (PT) or reactive thrombocytosis. Volumes greater than 337 cm3 correlated strongly ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1988.tb00188.x

    authors： Messinezy M,Chapman R,Dudley JM,Nunan TO,Pearson TC

    更新日期：1988-04-01 00:00:00

  • Whole blood folate values in pernicious anaemia: relation to treatment.

    abstract：:27 patients with pernicious anaemia, followed for a long period, were consecutively treated with three different vitamin B12 preparations, while during intervening period no therapy was given until signs of B12 deficiency developed. After vitamin B12 treatment, a peak whole blood folate value some 70% higher than the ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1987.tb00161.x

    authors： Magnus EM

    更新日期：1987-07-01 00:00:00

  • FCGR3A-158V/F polymorphism may correlate with the levels of immunoglobulin in patients with non-Hodgkin's lymphoma after rituximab treatment as an adjuvant to autologous stem cell transplantation.

    abstract：OBJECTIVES:Recent studies have indicated that patients who receive stem cell transplantation (SCT) and rituximab demonstrate an increased risk of developing hypogammaglobulinemia. Such hypogammaglobulinemia has been found to be due to delayed recovery of memory B cells with an abnormal cell marker expression and impair...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2008.01174.x

    authors： Nishio M,Endo T,Fujimoto K,Yamamoto S,Obara M,Yamaguchi K,Takeda Y,Goto H,Kasahara I,Sato N,Koike T

    更新日期：2009-02-01 00:00:00

  • Analysis of low and high grade B-cell lymphoma subtypes using semi-nested PCR and two primer sets.

    abstract：:Immunoglobulin gene rearrangements in B-cell lymphoma subtypes may not always be detected by PCR if only one primer set is applied. We therefore analysed a range of low and high grade B-cell lymphoma subtypes for monoclonality using PCR, to determine appropriate primer selection strategies for routine diagnostic use. ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1997.tb00966.x

    authors： Essop MF,Blakolmer K,Close PM,Manuel YE,Cornelius S

    更新日期：1997-09-01 00:00:00

  • Vacuoles in red cells from splenectomized subjects originate during cell life: association with glycosylated haemoglobin?

    abstract：:Whole blood from splenectomized subjects (n = 8) contained a substantial percentage of vacuolated ('pitted') red cells (34.7 +/- 8.3%), while blood from controls revealed none. The percentage of haemoglobin A1 (HbA1) had increased significantly compared with controls (p less than 0.01). Fractionation on cell density r...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1988.tb00231.x

    authors： De Haan LD,Werre JM,Ruben AM,Huls AH,de Gier J,Staal GE

    更新日期：1988-11-01 00:00:00

  • Acute myeloid leukemia in the pregnant patient.

    abstract：:Although acute myeloid leukemia (AML) mostly occurs in older patients, it could be seen in women of childbearing age. It is therefore not surprising that in some patients, the management of AML will be complicated by a coexistent pregnancy. However, the association of leukemia and pregnancy is uncommon. Its incidence ...

    journal_title：European journal of haematology

    pub_type： 杂志文章,评审

    doi：10.1111/ejh.12479

    authors： Thomas X

    更新日期：2015-08-01 00:00:00

  • Possible role of cytokine-induced tryptophan degradation in anaemia of inflammation.

    abstract：:Anaemia of inflammation (AI) is a frequent complication in patients suffering from chronic inflammatory disorders including infections, autoimmune and malignant disease. Cytokine imbalance with a shift towards T-helper (Th)1-type immune response seems to be important in the pathogenesis of this type of anaemia. Interf...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1046/j.0902-4441.2003.00197.x

    authors： Weiss G,Schroecksnadel K,Mattle V,Winkler C,Konwalinka G,Fuchs D

    更新日期：2004-02-01 00:00:00

  • Intensive remission induction therapy for chronic myeloid leukemia in blast phase with a goal of post-remission bone marrow transplant--a pilot study.

    abstract：:An intensive protocol utilizing mitoxantrone, high-dose cytarabine, vincristine, etoposide and methylprednisolone as induction therapy for chronic myeloid leukemia in blast transformation is described. Fourteen patients were treated, with a remission/second chronic phase achieved in 64%. None of the 3 patients older t...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1996.tb00488.x

    authors： Lipton JH,Messner HA,Curtis JE,Atkins HL,Minden MD

    更新日期：1996-07-01 00:00:00

  • Treatment of acute lymphoblastic leukaemia (ALL).

    abstract：:Forty-six consecutive patients with acute lymphoblastic leukaemia (ALL), having a median age of 23 years (range 14 to 64), underwent induction and consolidation chemotherapy with weekly parenteral vincristine, adriamycin, l-asparaginase and daily oral prednisone (VAAP), followed by standard central nervous system (CNS...

    journal_title：European journal of haematology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-0609.1992.tb00030.x

    authors： Jacobs P,Wood L

    更新日期：1992-08-01 00:00:00

  • Over-expression of tumor necrosis factor-alpha in bone marrow biopsies from patients with myelodysplastic syndromes: relationship to anemia and prognosis.

    abstract：OBJECTIVES:An excessive intramedullar progenitor cell apoptosis, to which elevated expression of tumor necrosis factor-alpha (TNF-alpha) might contribute, is considered the main cause of inefficient hematopoiesis in myelodysplastic syndromes (MDS). Enhanced bone marrow (BM) angiogenesis is regarded as an essential cofa...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2005.00551.x

    authors： Stifter G,Heiss S,Gastl G,Tzankov A,Stauder R

    更新日期：2005-12-01 00:00:00

  • Magnetic resonance imaging is superior to computed tomography and ultrasonography in imaging infectious liver foci in acute leukaemia.

    abstract：:We conducted a prospective study in order to compare ultrasonography, computed tomography and magnetic resonance imaging in the detection of liver foci in patients with acute leukaemia and clinical suspicion of hepatic candidiasis. 28 adult patients fulfilling set entry criteria after recovery from neutropenia were st...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1996.tb00300.x

    authors： Anttila VJ,Lamminen AE,Bondestam S,Korhola O,Färkkilä M,Sivonen A,Ruutu T,Ruutu P

    更新日期：1996-01-01 00:00:00

  • Leukemic transformation with trisomy 8 in essential thrombocythemia: a report of four cases.

    abstract：:Karyotype analysis of bone marrow samples was performed in 20 cases of essential thrombocythemia (ET) at the time of diagnosis. Three patients had karyotype abnormalities at the time of diagnosis; trisomy 8, deletion of Y, and del(9)(q?) in each. The patient who had trisomy 8 at the time of diagnosis underwent myeloid...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1034/j.1600-0609.2002.01601.x

    authors： Hirose Y,Masaki Y,Sugai S

    更新日期：2002-02-01 00:00:00

  • Clinical and hematological features of codon 17, A-T mutation of beta-thalassemia in Thai patients.

    abstract：:Forty-one patients with codon 17, A-T mutation of beta-thalassemia, which is commonly found in Thailand, were studied to determine whether it is possible to predict phenotypic severity from genetic factors. The clinical phenotype of homozygotes for codon 17, A-T and compound heterozygotes for codon 17, A-T and beta+-t...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1034/j.1600-0609.2001.00305.x

    authors： Laosombat V,Wongchanchailert M,Sattayasevana B,Wiriyasateinkul A,Fucharoen S

    更新日期：2001-02-01 00:00:00

  • On the interaction between cytosine arabinoside and etoposide in vivo and in vitro.

    abstract：:Cytosine arabinoside (ara-C) and etoposide are often used in combination in the treatment of acute myelocytic leukemia (AML). The intracellular phosphorylation of ara-C to its 5'-triphosphate (ara-CTP) is a prerequisite for its cytotoxic effects. It has been shown in vitro that etoposide can impair the formation of ar...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1993.tb00069.x

    authors： Liliemark J,Knochenhauer E,Gruber A,Pettersson B,Björkholm M,Peterson C

    更新日期：1993-01-01 00:00:00

  • Sensitivity and specificity of single-tube osmotic fragility test and its different methods as screening test for thalassemia trait: an alternative to expensive laboratory tests for resource-limited countries.

    abstract：OBJECTIVE:To determine the sensitivity and specificity of single-tube osmotic fragility (SOFT) and its different methods as screening test for thalassemia trait. METHODS:A cross-sectional study was conducted at Omair Sana Foundation. A total of 400 participants were included in the study. Three hundred were known thal...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12392

    authors： Ansari SH,Hanifa A,Saleem A,Ali SM,Hussain Z,Zohaib M,Akbar M,Rehman S,Hussain SR

    更新日期：2014-12-01 00:00:00

  • Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study.

    abstract：OBJECTIVE:A subset analysis of the randomised, phase 3, MDS-004 study to evaluate outcomes in patients with International Prognostic Scoring System (IPSS)-defined Low-/Intermediate (Int)-1-risk myelodysplastic syndromes (MDS) with isolated del(5q). METHODS:Patients received lenalidomide 10 mg/d (days 1-21; n = 47) or ...

    journal_title：European journal of haematology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/ejh.12380

    authors： Giagounidis A,Mufti GJ,Mittelman M,Sanz G,Platzbecker U,Muus P,Selleslag D,Beyne-Rauzy O,te Boekhorst P,del Cañizo C,Guerci-Bresler A,Nilsson L,Lübbert M,Quesnel B,Ganser A,Bowen D,Schlegelberger B,Göhring G,Fu T,Be

    更新日期：2014-11-01 00:00:00

  • Patient-specific analysis of FLT3 internal tandem duplications for the prognostication and monitoring of acute myeloid leukemia.

    abstract：OBJECTIVES:Internal tandem duplications (ITDs) of the fms-like tyrosine kinase 3 ( FLT3) gene occur in 13-35% of patients with acute myeloid leukemia (AML). FLT3-ITD is associated with poor clinical outcome and is an indication for allogeneic stem cell transplantation (allo-SCT). METHODS:To investigate FLT3-ITD length...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2012.01785.x

    authors： Schiller J,Praulich I,Krings Rocha C,Kreuzer KA

    更新日期：2012-07-01 00:00:00

  • Cladribine combined with rituximab (R-2-CdA) therapy is an effective salvage therapy in relapsed or refractory indolent B-cell non-Hodgkin lymphoma.

    abstract：:Although cladribine has been reported to be an active purine analog against indolent B-cell non-Hodgkin lymphoma (B-NHL), there are few reports of combination use of cladribine and rituximab. This multicenter phase II study evaluated the efficacy and toxicity of cladribine with rituximab (R-2-CdA) therapy in relapsed ...

    journal_title：European journal of haematology

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1600-0609.2010.01552.x

    authors： Nagai H,Ogura M,Kusumoto S,Takahashi N,Yamaguchi M,Takayama N,Kinoshita T,Motoji T,Ohyashiki K,Kosugi H,Matsuda S,Ohnishi K,Omachi K,Hotta T

    更新日期：2011-02-01 00:00:00

  • Plasma cell leukemia: from biology to treatment.

    abstract：:Plasma cell leukemia (PCL) is a very aggressive and rare form of malignant monoclonal gammopathy characterized by the presence of plasmocytes in peripheral blood. It is classified as primary PCL occuring 'de novo', or as secondary PCL in patients with relapsed/refractory multiple myeloma. Primary PCL is a distinct cli...

    journal_title：European journal of haematology

    pub_type： 杂志文章,评审

    doi：10.1111/ejh.12533

    authors： Jelinek T,Kryukov F,Rihova L,Hajek R

    更新日期：2015-07-01 00:00:00

  • Monosomy 7 predisposes to diabetes insipidus in leukaemia and myelodysplastic syndrome.

    abstract：:We studied the chromosomes in the bone marrow of 4 patients who had both diabetes insipidus (DI) and acute non-lymphocytic leukaemia. Clinical findings suggested that, in each case, myelodysplastic syndrome had preceded the onset of acute leukaemia. Two other such patients described in the literature had had a banded ...

    journal_title：European journal of haematology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1600-0609.1987.tb01447.x

    authors： de la Chapelle A,Lahtinen R

    更新日期：1987-11-01 00:00:00

  • Pathophysiology, diagnosis, and treatment of paroxysmal nocturnal hemoglobinuria: a review.

    abstract：:Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder of the hematopoietic stem cell that makes blood cells more sensitive to the action of complement. Patients experience intravascular hemolysis, smooth muscle dystonia, renal failure, arterial and pulmonary hypertension, recurrent infectious diseases and ...

    journal_title：European journal of haematology

    pub_type： 杂志文章,评审

    doi：10.1111/ejh.12543

    authors： Devalet B,Mullier F,Chatelain B,Dogné JM,Chatelain C

    更新日期：2015-09-01 00:00:00

  • HIV+ MALT lymphoma remission induced by highly active antiretroviral therapy alone.

    abstract：:MALT lymphoma is usually described in association with Helicobacter pylori, HCV, HHV8, Campylobacter jejuni or in a setting of overreactive immunity. In HIV(+) patients, MALT lymphoma is most commonly described in children. We describe here an original case of HIV(+) MALT lymphoma with bronchial, conjuctival and laryn...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2004.00339.x

    authors： Girard T,Luquet-Besson I,Baran-Marszak F,Raphaël M,Boué F

    更新日期：2005-01-01 00:00:00

  • Is valganciclovir really effective in primary effusion lymphoma: case report of an HIV(-) EBV(-) HHV8(+) patient.

    abstract：:Primary effusion lymphoma (PEL) is a human herpesvirus 8 (HHV8) associated lymphoproliferative disease characterized by effusions in body cavities, and lack of tumor mass. Valganciclovir is a treatment option in PEL, however, little is known about its clinical efficacy. Ganciclovir has been reported to be effective in...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12174

    authors： Ozbalak M,Tokatlı I,Özdemirli M,Tecimer T,Ar MC,Örnek S,Koroglu A,Laleli Y,Ferhanoglu B

    更新日期：2013-11-01 00:00:00

  • Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma.

    abstract：OBJECTIVES:Mantle cell lymphoma (MCL) is an incurable disease with an aggressive course and novel treatment strategies are urgently needed. The purpose of this study was to evaluate the effects of histone deacetylase (HDAC) inhibitors, a new group of antiproliferative agents, on human MCL cells. METHODS:Three MCL cell...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2005.00546.x

    authors： Heider U,Kaiser M,Sterz J,Zavrski I,Jakob C,Fleissner C,Eucker J,Possinger K,Sezer O

    更新日期：2006-01-01 00:00:00

  • Congenital haemolytic anaemia in a low birth weight infant due to congenital stomatocytosis.

    abstract：:A baby girl born at 31 weeks gestation showed severe haemolytic anaemia and hyperbilirubinaemia which led to exchange transfusion within the first 12 hours of life. There was no blood group incompatibility between mother and child but there was a marked stomatocytosis of the baby's red blood cells. Family history reve...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1991.tb00554.x

    authors： Huppi PS,Ott P,Amato M,Schneider H

    更新日期：1991-07-01 00:00:00