Oxidation of albumin is enhanced in the presence of uremic toxins.

abstract：:Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with gene expression remai...

journal_title：Renal failure

authors： Wang H,Huang N,Liu Y,Cang J,Xue Z

更新日期：2016-07-01 00:00:00

abstract：:Objectives: To improve the mouse model of relief for unilateral ureteral obstruction (RUUO) and explore the pathological process of renal fibrosis after the obstruction was relieved. Methods: C57BL/6 mice in model group were randomly divided into RUUO group, improved RUUO group, and UUO group. After leaving Unilateral...

journal_title：Renal failure

authors： Song J,Liu J,Luo J,Zhang Q,Xia Y,Shao Q,Sun C,Jiang C,Zhang M,Zhu W

更新日期：2019-11-01 00:00:00

abstract：:In vascular smooth muscle, calcium overload is a highly pathogenic event, which increases with advancing age. An increase in the calcium content of arterial wall may be produced in rats by treatment with vitamin D3. The aim of this study was to evaluate the renal clearance of sulfanilamide (a model organic anion, pref...

journal_title：Renal failure

authors： Quaglia NB,Brandoni A,Ferri A,Torres AM

更新日期：2003-05-01 00:00:00

abstract：:While the fractional excretion of solutes have long been considered excellent research tools to investigate tubular physiology, their clinical use has become common over the last 40 years in the diagnoses of many disorders; however, none have reached the clinical utility of the fractional excretion of sodium in the ab...

journal_title：Renal failure

authors： Diskin CJ,Stokes TJ,Dansby LM,Radcliff L,Carter TB

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN pa...

journal_title：Renal failure

authors： Reis KA,Ebinç FA,Koç E,Demirci H,Erten Y,Güz G,Derici UB,Bali M,Söylemezoğlu O,Arınsoy T,Sindel S

更新日期：2011-01-01 00:00:00

abstract：:The study of urinary proteins is an important tool in the screening and diagnosis of patients with renal impairment. Quantification of total proteins, although useful, can provide only limited information. Gel electrophoresis of urine samples may provide more detailed information. ...

journal_title：Renal failure

authors： Behets GJ,De Broe ME

更新日期：1999-05-01 00:00:00

abstract：RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...

journal_title：Renal failure

authors： Prakash J,Pant P,Singh AK,Sriniwas S,Singh VP,Singh U

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Prolonged corticosteroid (CS) use induces osteoporosis; the pathogenesis of this condition is multifactorial and includes CS-induced hypercalciuria. We investigated the course of hypercalciuria and related markers of bone metabolism parameters during and after the CS treatment. MATERIALS AND M...

journal_title：Renal failure

authors： Duzen O,Erkoc R,Begenik H,Soyoral YU,Aldemir MN

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

journal_title：Renal failure

authors： Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

更新日期：2014-02-01 00:00:00

abstract：:Rhabdomyolysis ranges from an asymptomatic illness with elevated creatine kinase levels to a life-threatening condition associated with extreme elevations in creatine kinase, electrolyte imbalances, acute renal failure, and disseminated intravascular coagulation. The most common causes are crush injury, overexertion, ...

journal_title：Renal failure

authors： Celik H,Celik O,Guldiken S,Inal V,Puyan FO,Tugrul A

更新日期：2014-02-01 00:00:00

abstract：:Renal biopsy data indicate that tubular epithelial cells serve as a reservoir for HIV-1 infection. We studied the effect of HIV-1 gp120 envelope gene expression on tubular cell apoptosis. HIV-1 gp120 was expressed in a lentiviral vector pHR-CMV-IRES2-EGFP-DeltaB. This plasmid construct was used to produce pseudotyped ...

journal_title：Renal failure

authors： Vashistha H,Husain M,Kumar D,Singhal PC

更新日期：2009-01-01 00:00:00

abstract：:Abnormal glucose metabolism in uremia may result from a complex interplay between decreased insulin secretion and insulin resistance. Recent studies report beneficial effect of biotin administration in glucose metabolism in diabetic animals and in a small number of patients with diabetes mellitus. The aim of the prese...

journal_title：Renal failure

authors： Koutsikos D,Fourtounas C,Kapetanaki A,Agroyannis B,Tzanatos H,Rammos G,Kopelias I,Bosiolis B,Bovoleti O,Darema M,Sallum G

更新日期：1996-01-01 00:00:00

abstract：AIMS:The use of hemodialysis temporary dual-lumen catheters is often complicated by infections, which may be a significant cause of death among patients with end stage renal disease (ESRD). The aim of this study was to assess the incidence of bacteremia and bacterial colonization related to non-tunneled, non-cuffed, du...

journal_title：Renal failure

authors： de Freitas LW,Neto MM,Nascimento MM,Figueiredo JF

更新日期：2008-01-01 00:00:00

abstract：:Creation of arteriovenous fistula (AVF) may lead to left ventricle hypertrophy and predispose for development or worsening of heart failure. It was postulated to reduce access blood flow if exceeded 2 L/min or cardiac index was higher than 3.0 L/min/m(2). Numbers of techniques decreasing flow were described. The major...

journal_title：Renal failure

authors： Letachowicz K,Kusztal M,Gołębiowski T,Letachowicz W,Weyde W,Klinger M

更新日期：2016-08-01 00:00:00

abstract：:Autosomal dominant polycystic disease (ADPKD) is one of the most common monogenic disorders, and globally is among the most common hereditary causes of end stage kidney disease. Until recently, the causes of this disease remained obscure. However, in the past decade there have been enormous advances in the understandi...

journal_title：Renal failure

authors： Kazancioglu R,Gursu M

更新日期：2015-05-01 00:00:00

abstract：AIM:When peritoneal fibrosis (PF) causes ultrafiltration failure in peritoneal dialysis (PD) patients, PD has to be discontinued. Currently, there is no effective way to relieve PF. In this study, we aimed to determine whether miR-15a-5p is involved in PF and to determine the underlying mechanism. METHODS:Six normal r...

journal_title：Renal failure

authors： He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

更新日期：2020-11-01 00:00:00

abstract：:Dyslipoproteinemia and oxidative modification of low-density lipoprotein (oxLDL) contribute to the development of oxidative stress and atherosclerosis in chronic kidney disease (CKD). On the contrary, high-density lipoprotein cholesterol (HDL-C), especially HDL3-C subtype, has protective effect against oxidative damag...

journal_title：Renal failure

authors： Samouilidou EC,Karpouza AP,Kostopoulos V,Bakirtzi T,Pantelias K,Petras D,Tzanatou-Exarchou H,J Grapsa E

更新日期：2012-01-01 00:00:00

abstract：:Glomerular function shows a progression directly correlated to gestational age (GA) and postnatal age in preterm infants. In preterms, glomerular filtration rate (GFR) is significantly lower than in term infants, and it matures more slowly in the postnatal period. In infants with very low GA, due to decreased GFR, nor...

journal_title：Renal failure

authors： Aydemir O,Erdeve O,Oguz SS,Uras N,Dilmen U

更新日期：2011-01-01 00:00:00

abstract：:Urinary N-acetyl-β-d-glucosaminidase (NAG) has been suggested as a marker for early diabetic nephropathy. This study aimed to prospectively investigate the relationship between asymptomatic leukocyturia (ASL) and NAG in women. One hundred and five female outpatients aged 31-86 years were selected for a 10-year follow-...

journal_title：Renal failure

authors： Sekimizu K,Suzuki T,Igari Y,Okazaki M,Hashimoto M,Suzuki K,Ouchi M,Watanabe K,Nakano H,Oba K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:A unique form of postinfectious glomerulonephritis (PIGN) with IgA-dominant deposition mimicking IgA nephropathy has been increasingly reported. METHODS:We compared the clinical and histological features of 12 patients with postinfectious IgA-dominant glomerulonephritis to 134 patients with idiopathic IgA n...

journal_title：Renal failure

authors： Wen YK,Chen ML

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:To investigate the effect of Atorvastatin (ATO) and Rosuvastatin (ROS) on blood lipid, high sensitivity CRP (hs-CRP), interleukin-6 (IL-6), albumin (ALB), prealbumin (PA), and transferring (TF) in maintenance hemodialysis (MHD) patients. METHODS:Eighty MHD patients were enrolled and divided into two group...

journal_title：Renal failure

authors： Tian J,Hou X,Hu L,Chen T,Wu K,Cai C,Bai X

更新日期：2017-11-01 00:00:00

abstract：AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

journal_title：Renal failure

authors： Zhou C,Shan Y,Zhao H,He P

更新日期：2011-01-01 00:00:00

abstract：:The present work examines the role of uremia and the effect of dialysis treatment on red blood cells (RBCs) membrane properties of hemodialysis patients. The results showed that, the uremic patients had a lower values of erythrocyte deformability than that of healthy control subject. The median osmotic fragility (MOF)...

journal_title：Renal failure

authors： Ibrahim FF,Ghannam MM,Ali FM

更新日期：2002-11-01 00:00:00

abstract：PRINCIPLES:Coumadin-induced renal and retroperitoneal hemorrhages are rare. Clinical and laboratory findings are not specific for the diagnosis. Computed tomography (CT) has some advantages in the evaluation of these patients. The aim of this study is to report our experience regarding renal and retroperitoneal hemorrh...

journal_title：Renal failure

authors： Danaci M,Kesici GE,Kesici H,Polat C,Belet U

更新日期：2006-01-01 00:00:00

abstract：:The derangements in bone metabolism in patients with chronic renal failure (CRF) are summarized as uremic bone disease (UBD). In this study, we planned to determine the serum prolidase to compare it with the other biochemical markers. This study was performed on 44 patients (19 females, 25 males, mean age = 56.8 +/- 1...

journal_title：Renal failure

authors： Evrenkaya TR,Atasoyu EM,Kara M,Unver S,Gultepe M

更新日期：2006-01-01 00:00:00

abstract：:Approximately one-third of all dialysis patients have mild to moderate malnutrition, while 6-8% have severe malnutrition, which is associated with increased morbidity and mortality rates and numerous pre-existing factors directly correlated with, or existing prior to, replacement hemodialysis. However, moderate to sev...

journal_title：Renal failure

authors： Lacquaniti A,Bolignano D,Campo S,Perrone C,Donato V,Fazio MR,Buemi A,Sturiale A,Buemi M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

journal_title：Renal failure

authors： Borazan A,Cavdar Z,Saglam F

更新日期：2007-01-01 00:00:00

abstract：:Acute iron poisoning is a common and potentially serious problem in the pediatric population. Early recognition and treatment is crucial for a better outcome and to prevent morbidity and mortality. An 18-year-old female, who had accidental ingestion of 50 tablets of ferrous sulfate (100 mg of elemental iron per 335 mg...

journal_title：Renal failure

authors： Gumber MR,Kute VB,Shah PR,Vanikar AV,Patel HV,Balwani MR,Ghuge PP,Trivedi HL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although adequate peritoneal dialysis is not well defined, Kt/Vurea has been used as an index, and various values have been proposed. However, conflicting evidence existed regarding the appropriateness of using Kt/Vurea to define dialysis adequacy and its optimal value. Therefore, the present study performed...

journal_title：Renal failure

authors： Zhe XW,Shan YS,Cheng L,Tian XK,Wang T

更新日期：2007-01-01 00:00:00

abstract：:Although sudden sensorineural hearing loss (SSNHL) affects chronic kidney disease (CKD) patients more frequently than non-CKD patients, few reports have described SSNHL in dialysis patients. We aimed to review the characteristics of SSNHL in chronic dialysis patients and evaluate treatment responses to steroid therapy...

journal_title：Renal failure

authors： Kang SM,Lim HW,Yu H

更新日期：2018-11-01 00:00:00