Abstract:
:Acute iron poisoning is a common and potentially serious problem in the pediatric population. Early recognition and treatment is crucial for a better outcome and to prevent morbidity and mortality. An 18-year-old female, who had accidental ingestion of 50 tablets of ferrous sulfate (100 mg of elemental iron per 335 mg tablet), 100 mg/kg of elemental iron, developed acute gastrointestinal and neurologic signs of toxicity and severe anion gap metabolic acidosis. The patient had received gastrointestinal decontamination, deferoxamine (DFO) infusion, and hemodialysis (HD) resulting in a decrease in serum iron concentration from 2150 to 160 mcg/dL at 24-h post-ingestion and improved mental status. Our cases demonstrate that HD may assist in decreasing serum iron concentration and improving clinical status in patients with massive overdose and life-threatening toxicity.
journal_name
Ren Failjournal_title
Renal failureauthors
Gumber MR,Kute VB,Shah PR,Vanikar AV,Patel HV,Balwani MR,Ghuge PP,Trivedi HLdoi
10.3109/0886022X.2013.790299subject
Has Abstractpub_date
2013-01-01 00:00:00pages
729-31issue
5eissn
0886-022Xissn
1525-6049journal_volume
35pub_type
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