Analysis of HMPAO SPECT scans in head injury using Statistical Parametric Mapping.

Abstract:

:The paper examines the ability of Statistical Parametric Mapping (SPM) to contribute towards the quantitative analysis of HMPAO SPECT images containing lesions. A validation study is described in which SPECT images were created that contained synthetic lesions and were analysed with SPM. The study established a set of guidelines concerning the alignment, smoothing, and statistical analysis of images. These were then applied to analysis of SPECT scans from head injured patients. A demonstration is given of the use of SPM to identify localised blood flow abnormalities associated with cognitive deficits after head injury. Correlations between blood flow abnormalities and a test of visual memory are illustrated.

journal_name

Behav Neurol

journal_title

Behavioural neurology

authors

Stamatakis EA,Wilson JT,Wyper DJ

doi

10.1155/2000/681916

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

29-37

issue

1-2

eissn

0953-4180

issn

1875-8584

journal_volume

12

pub_type

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