Intracellular dynamics of steroid hormone receptor.

abstract：:We excised the dorsal part of the optic vesicle of chick embryos at stages 13-14 (embryonic day 2). The remainder of the optic vesicle reoganized and developed a small eye. This study was undertaken to determine how locus specificity is kept within the reorganized retina. The projection pattern from the reorganized ey...

journal_title：Neuroscience research

authors： Matsuno T,Itasaki N,Ichijo H,Nakamura H

更新日期：1992-10-01 00:00:00

abstract：:RNA editing provides a post-transcriptional mechanism to increase structural heterogeneity of gene products. Recently, the alpha3 subunit of the GABAA receptors has been shown to undergo RNA editing. As a result, a highly conserved isoleucine residue in the third transmembrane domain is replaced with a methionine. To ...

journal_title：Neuroscience research

authors： Nimmich ML,Heidelberg LS,Fisher JL

更新日期：2009-04-01 00:00:00

abstract：:We studied the ascending and descending axonal trajectories of excitatory vestibular neurons related to the anterior semicircular canal, by means of local stimulation and spike-triggered signal averaging techniques in anesthetized cats. More than 200 vestibular neurons related to the ampullary nerve of the anterior se...

journal_title：Neuroscience research

authors： Uchino Y,Hirai N

更新日期：1984-10-01 00:00:00

abstract：:Effect of serotonin on nitric oxide (NO) production in the ventral nerve cord (VNC) of the earthworm Eisenia fetida was investigated by a bio-imaging and an electrochemical technique. In the bio-imaging, the spatial pattern of NO production in VNC was visualized using an NO-specific fluorescent dye, diaminofluorescein...

journal_title：Neuroscience research

authors： Kitamura Y,Naganoma Y,Horita H,Ogawa H,Oka K

更新日期：2001-10-01 00:00:00

abstract：:In rat models of Parkinson's disease, injections of 6-hydroxydopamine (6-OHDA) into different areas of the basal ganglia result in dopaminergic neurodegeneration in the substantia nigra. The extent and time course of the dopaminergic lesions varies between the models. While the effects on neurons have been extensively...

journal_title：Neuroscience research

authors： Henning J,Strauss U,Wree A,Gimsa J,Rolfs A,Benecke R,Gimsa U

更新日期：2008-12-01 00:00:00

abstract：:The purposes of the present study were to determine which upper airway movements cause a difference in the expiratory airflow pathway between sneezing and coughing, and to develop a new animal model for studying the neural mechanism of sneezing in paralyzed animals, i.e. fictive sneezing. We compared the upper airway ...

journal_title：Neuroscience research

authors： Satoh I,Shiba K,Kobayashi N,Nakajima Y,Konno A

更新日期：1998-10-01 00:00:00

abstract：:Area TE sends dense projections to the perirhinal cortex in macaque monkeys, an area in which we previously observed flexible signals regarding upcoming reward outcomes during a conditional-association cued-reward task. To investigate neuronal processing during the generation of information on upcoming reward outcomes...

journal_title：Neuroscience research

authors： Ohyama K,Sugase-Miyamoto Y,Matsumoto N,Sato C,Shidara M

更新日期：2014-11-01 00:00:00

abstract：:Increased levels of proinflammatory cytokines have been implicated in schizophrenia; however, their pathophysiological roles in abnormal brain dysfunctions remain unclear. We evaluated the effect of proinflammatory cytokines on a high-fat diet (HFD)-induced prepulse inhibition (PPI) deficits in the acoustic startle re...

journal_title：Neuroscience research

authors： Wakabayashi C,Kunugi H

更新日期：2019-10-01 00:00:00

abstract：:We studied developmental changes in respiratory-like C4 activity and respiratory-related neurons in the ventrolateral medulla (VLM) of brainstem-spinal cord preparations from rat fetuses after embryonic day 16 (E16). In addition to respiratory nerve activity, non-respiratory activity was recorded from the C4 ventral r...

journal_title：Neuroscience research

authors： Onimaru H,Homma I

更新日期：2002-03-01 00:00:00

abstract：:Many different kinds of voltage-gated ion channels (Na+ channels, K+ channels, Ca2+ channels) exist at neuronal dendrites. Integration of dendritic electric signals (excitatory postsynaptic potentials (EPSPs), inhibitory postsynaptic potentials (IPSPs) and action potentials) and/or non-electric signals (Ca2+ and secon...

journal_title：Neuroscience research

authors： Takagi H

更新日期：2000-07-01 00:00:00

abstract：:The change in [Ca2+]i, in a retinal rod outer segment to flash and step stimuli was simulated. The present model included inward and outward calcium fluxes through cation channels and an Na-Ca-K exchanger, respectively, calcium buffers, and diffusion through the interdiskal space of cytoplasm and incisures. Under cont...

journal_title：Neuroscience research

authors： Ichikawa K

更新日期：1996-06-01 00:00:00

abstract：:A significant activity of [3H]glutamate binding was detected in homogenate particulate preparations obtained from the rat pituitary, in addition to central structures including the cerebral cortex. In contrast to the cerebral binding, the pituitary binding was significantly inhibited by Na+ ions. It was also found tha...

journal_title：Neuroscience research

authors： Yoneda Y,Ogita K

更新日期：1986-07-01 00:00:00

abstract：:Striatonigral axons co-release GABA and substance P (SP) at their target sites, but little is known about the action of SP at nigral level. Therefore, we studied immunohistochemically the cellular and subcellular localization of SP and its high affinity receptors neurokinin-1 (NK-1R) and neurokinin-3 (NK-3R) at nigral...

journal_title：Neuroscience research

authors： Lévesque M,Wallman MJ,Parent R,Sík A,Parent A

更新日期：2007-03-01 00:00:00

abstract：:Long-term depression at parallel fiber-Purkinje cell synapses plays a principal role in learning in the cerebellum, which acts as a supervised learning machine. Recent experiments demonstrate various forms of synaptic plasticity at different sites within the cerebellum. In this article, we take into consideration syna...

journal_title：Neuroscience research

authors： Yamazaki T,Lennon W

更新日期：2019-11-01 00:00:00

abstract：:Using a mouse Thy-1 allelic system (an AKR strain of Thy-1.1 was used as the host and a BALB/c strain of Thy-1.2 as the graft), characteristics of transplant-to-host axon projection and synapse formation of the olfactory bulb (OB) were studied in the hippocampal formation by immunohistochemical and ultrastructural exa...

journal_title：Neuroscience research

authors： Fujii M,Hayakashi T

更新日期：1995-12-01 00:00:00

abstract：:Efferent neurons to the cochlea in the guinea pig were observed in the superior olivary complex and ventral lateral lemniscal nuclei after injection of WGA-HRP into the cochlea via the round window. Of HRP-labeled nerve cells found in the brainstem, about 60% and 10% were located in the ipsilateral lateral superior ol...

journal_title：Neuroscience research

authors： Tokunaga A

更新日期：1988-10-01 00:00:00

abstract：:Narcolepsy is a chronic sleep disorder marked by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucinations. Since the discovery of sleep onset REM periods (SOREMPs) in narcoleptic patients, narcolepsy has often been regarded as a disorder of REM sleep generation: REM sleep intrudes in act...

journal_title：Neuroscience research

authors： Nishino S,Riehl J,Hong J,Kwan M,Reid M,Mignot E

更新日期：2000-12-01 00:00:00

abstract：:The critical flicker-fusion frequency (CFF), defined as the frequency at which a flickering light is indistinguishable from a continuous light, is a useful measure of visual temporal resolution. The mouse CFF has been studied by electrophysiological approaches such as recordings of the electroretinogram (ERG) and the ...

journal_title：Neuroscience research

authors： Nomura Y,Ikuta S,Yokota S,Mita J,Oikawa M,Matsushima H,Amano A,Shimonomura K,Seya Y,Koike C

更新日期：2019-11-01 00:00:00

abstract：:Neurons in the inferior temporal (IT) cortex respond not only to the shape, color or texture of objects, but to the horizontal positional disparity of visual features in the right and left retinal images. IT neurons with similar shape selectivity cluster in columns. In this study, we examined how IT neurons are spatia...

journal_title：Neuroscience research

authors： Yoshiyama K,Uka T,Tanaka H,Fujita I

更新日期：2004-02-01 00:00:00

abstract：:Vestibular nuclear neurons that mediate horizontal canal signals to the ipsilateral medial rectus motoneurons were explored in anesthetized and decerebrate rabbits. These neurons were identified by four criteria: (1) they were activated monosynaptically by ipsilateral vestibular nerve stimulation and (2) antidromicall...

journal_title：Neuroscience research

authors： Kawaguchi Y

更新日期：1985-08-01 00:00:00

abstract：:Development of neurofibrillary tangles (NFTs) is a pathological hallmark in various neurodegenerative disorders including Alzheimer's disease (AD). Recently, we identified a granular tau oligomer having a pre-filamentous structure. To determine the role of this oligomer in NFT formation, we quantified the amount of gr...

journal_title：Neuroscience research

authors： Maeda S,Sahara N,Saito Y,Murayama S,Ikai A,Takashima A

更新日期：2006-03-01 00:00:00

abstract：:The effects of 5-HT3-receptor-related agents on long-term potentiation (LTP) in the mossy fiber-CA3 system were studied in guinea pig hippocampal slices. 5-HT3 receptor agonists, 1-(m-chlorophenyl)-biguanide (mCPBG) and 2-methyl serotonin (2-Me-5-HT) significantly attenuated the magnitude of LTP of the population spik...

journal_title：Neuroscience research

authors： Maeda T,Kaneko S,Satoh M

更新日期：1994-01-01 00:00:00

abstract：:Hypnosis often leads people to obey a suggestion of movement and to lose perceived voluntariness. This inexplicable phenomenon suggests that the state of the motor system may be altered by hypnosis; however, objective evidence for this is still lacking. Thus, we used transcranial magnetic stimulation of the primary mo...

journal_title：Neuroscience research

authors： Takarada Y,Nozaki D

更新日期：2014-08-01 00:00:00

abstract：:The cranial nerves and the brain fiber systems of the medaka (Oryzias latipes) fry are revealed by a whole-mount staining method. Newly hatched fry of an albino strain of the medaka were fixed, partially digested with trypsin, treated in 1% Triton X-100, and finally immunohistochemically stained using anti-neurofilame...

journal_title：Neuroscience research

authors： Ishikawa Y,Hyodo-Taguchi Y

更新日期：1994-06-01 00:00:00

abstract：:One important aspect of empathy is a "resonance mechanism", which includes emotional cue detection, facial mimicry (measured by electromyography, EMG) and a specific cortical response. This study explored the convergence of these three measures of affective empathy. The twenty students who took part in the study were ...

journal_title：Neuroscience research

authors： Balconi M,Bortolotti A,Gonzaga L

更新日期：2011-11-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is a recently identified member of the secretin/vasoactive intestinal polypeptide (VIP) family. There are at least two types of receptor for PACAP: type I (PACAPR), which specifically binds PACAP; and type II (VIP/PACAPR), which binds both PACAP and VIP. The l...

journal_title：Neuroscience research

authors： Shioda S,Shuto Y,Somogyvari-Vigh A,Legradi G,Onda H,Coy DH,Nakajo S,Arimura A

更新日期：1997-08-01 00:00:00

abstract：:In our previous study using the whole-cell patch clamp technique combined with reverse transcription-polymerase chain reaction analysis in rat brainstem slices, we demonstrated that the classification of neurons in the medial vestibular nucleus (MVN) based on three membrane properties detected as voltage response prop...

journal_title：Neuroscience research

authors： Saito Y,Ozawa S

更新日期：2007-10-01 00:00:00

abstract：:We generated a transgenic rat strain with a missense mutation in V286L (V286L-TG), in the gene encoding the neuronal nicotinic acetylcholine receptor β2 subunit (CHRNB2) found in patients with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). To confirm that V286L-TG rats exhibit seizures similar to those o...

journal_title：Neuroscience research

authors： Shiba Y,Mori F,Yamada J,Migita K,Nikaido Y,Wakabayashi K,Kaneko S,Okada M,Hirose S,Ueno S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Global field synchronization (GFS) has recently been introduced to measure functional synchronization in frequency-domain EEG data. This study explored GFS values and its clinical significance in patients with Alzheimer's disease (AD). METHOD:EEGs were recorded from 22 AD patients and 23 age-matched healthy...

journal_title：Neuroscience research

authors： Park YM,Che HJ,Im CH,Jung HT,Bae SM,Lee SH

更新日期：2008-10-01 00:00:00

abstract：:The subthalamic nucleus occupies a position in the indirect pathway of basal ganglia circuit, which plays an important role in the movement regulation. Zolpidem is an imidazopyridine agonist with a high affinity on the benzodiazepine site of GABA(A) receptors containing alpha 1 subunit. Recently, zolpidem has been rep...

journal_title：Neuroscience research

authors： Chen L,Xie JX,Fung KS,Yung WH

更新日期：2007-05-01 00:00:00