Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings.

abstract：OBJECTIVE:Metabolic syndrome (MetS) is associated with insulin resistance and increases the cardiovascular risk. Oxidative stress constitutes a potential mechanism that links insulin resistance and cardiovascular disease. The aim of this study was to analyze the relationship of NADPH oxidase activation with insulin res...

journal_title：Journal of hypertension

authors： Fortuño A,Bidegain J,San José G,Robador PA,Landecho MF,Beloqui O,Díez J,Zalba G

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP)-lowering trials studying efficacy mostly assesses binary outcome events, for example stroke/no stroke. Analysis of ordered categorical vascular events (e.g. three levels: fatal stroke/nonfatal stroke/no stroke) provides information on severity and is more powerful statistically than analy...

journal_title：Journal of hypertension

authors： Geeganage CM,Tracy M,Bath MW,Bath PM

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:Night-time blood pressure (BP) - prognostically more important than circadian BP variability - has not been evaluated for quantitative associations with objective sleep quality in large populations. METHODS:The cross-sectional study measured actigraphic sleep parameters and night-time BP for two nights in 1...

journal_title：Journal of hypertension

authors： Oume M,Obayashi K,Asai Y,Ogura M,Takeuchi K,Tai Y,Kurumatani N,Saeki K

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:The upward trends in the prevalence and control of hypertension in Chinese adults have been described, but recent trends based on the most recent guidelines are unavailable. We examined recent trends in the prevalence, awareness, treatment and control of hypertension among Chinese adults from 1991 to 2015 bas...

journal_title：Journal of hypertension

authors： Ma S,Yang L,Zhao M,Magnussen CG,Xi B

更新日期：2020-11-11 00:00:00

abstract：OBJECTIVE:To compare the elastic properties of the ascending aorta and ventricular-arterial coupling (VAC) in women with a previous pregnancy complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome, women who experienced preeclampsia, and healthy controls. METHODS:Women with a history of p...

journal_title：Journal of hypertension

authors： Sciatti E,Orabona R,Prefumo F,Vizzardi E,Bonadei I,Valcamonico A,Metra M,Frusca T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The renin-angiotensin system plays an important role in blood pressure control. Recently the mouse Ren-2 renin gene was introduced into the genome of rats, producing low-renin hypertensive animals. The aim of the present study was to characterize the pharmacological and morphological properties of mesenteric ...

journal_title：Journal of hypertension

authors： Thybo NK,Korsgaard N,Mulvany MJ

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Enhanced central sympathetic outflow is an indicator of the prognosis of heart failure. Although the central sympatholytic drug moxonidine is an established therapeutic strategy for hypertension, its benefits for hypertensive heart failure are poorly understood. In the present study, we investigated the effe...

journal_title：Journal of hypertension

authors： Honda N,Hirooka Y,Ito K,Matsukawa R,Shinohara K,Kishi T,Yasukawa K,Utsumi H,Sunagawa K

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Combination therapy is needed to control blood pressure (BP) in a large number of hypertensive patients with diabetes mellitus. Adherence to treatment is a major clinical problem; therefore, the time duration of the antihypertensive action of a drug determines BP control when a dose is skipped. OBJECTIVES...

journal_title：Journal of hypertension

authors： Redon J,Pichler G,Missed Dose Study Group.

更新日期：2016-02-01 00:00:00

abstract：:Although the consequences of hypertension are universal, blacks (African-Americans or indigenous Africans) have been the subject of a differential approach to causation, outcome, and treatment. Blacks have a greater propensity to salt sensitivity and suppressed plasma renin suggesting a predisposition to sodium retent...

journal_title：Journal of hypertension

authors： Rayner BL,Spence JD

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Treating hypertension in those aged at least 80 years is now recommended; however, the best antihypertensive to choose remains unexplored. Calcium channel blocker (CCB) use has been associated with a decreased risk of incident dementia in a younger hypertensive group but with an increased risk of cognitive de...

journal_title：Journal of hypertension

authors： Peters R,Booth A,Peters J

更新日期：2014-10-01 00:00:00

abstract：:Hypertension was induced in marmosets by ligating the minor branch of one renal artery. The blood pressure (BP), measured by a tail-cuff method, increased to hypertensive levels within 4-5 weeks and the maximum increases occurred after 4-15 weeks (BP, mean +/- s.e.m. was 120 +/- 3 and 152 +/- 6 mmHg before and 10 week...

journal_title：Journal of hypertension

authors： Neisius D,Wood JM

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:To audit the performances of the analytes used in the diagnosis of pheochromocytoma and to present a graphical guideline to help the diagnosis. DESIGN:A 5 year retrospective study. SETTINGS:Laboratory and departments of a university hospital. PARTICIPANTS:In-patients, suspected of bearing a pheochromocytom...

journal_title：Journal of hypertension

authors： Gardet V,Gatta B,Simonnet G,Tabarin A,Chêne G,Ducassou D,Corcuff JB

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:The heptapeptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a versatile, endogenous inhibitor of the renin-angiotensin system (RAS). As the therapeutic response to exogenous RAS inhibitors, such as AT1 receptor antagonists, is altered by changes in salt intake, we investigated the effect of a low, n...

journal_title：Journal of hypertension

authors： Roks AJ,Nijholt J,van Buiten A,van Gilst WH,de Zeeuw D,Henning RH

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between admission SBP and subsequent cardiovascular and all-cause mortality in older patients hospitalized for acute coronary syndrome (ACS). METHODS:This is a retrospective observational study. Data from the CBD Bank (Cardiovascular Center Beijing Friendship Hospital Database...

journal_title：Journal of hypertension

authors： Jiang C,Wu S,Wang M,Zhao X,Li H

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis in the two-kidney, o...

journal_title：Journal of hypertension

authors： Vethe H,Finne K,Skogstrand T,Vaudel M,Vikse BE,Hultström M,Placier S,Scherer A,Tenstad O,Marti HP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...

journal_title：Journal of hypertension

authors： Giubertoni E,Bertelli L,Bartolacelli Y,Origliani G,Modena MG

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between birth characteristics and blood pressure at age 20 years and to assess whether effects of birth weight on blood pressure are amplified from childhood to adulthood. DESIGN:A longitudinal study of 584 men and women from Adelaide, Australia, examined previously at 8 years an...

journal_title：Journal of hypertension

authors： Moore VM,Cockington RA,Ryan P,Robinson JS

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To investigate gender-dependent difference in the free cytosolic calcium concentration ([Ca2+ ]i ) response to angiotensin II (Ang II) in vascular smooth muscle cells (VSMC) isolated from spontaneously hypertensive rats (SHR). To further evaluate this gender-dependent difference by studying the role of thapsi...

journal_title：Journal of hypertension

authors： Loukotová J,Kunes J,Zicha J

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Familial hyperkalaemic hypertension (FHH) is a Mendelian form of low-renin hypertension characterized by hyperkalaemia and hyperchloraemic acidosis despite a normal glomerular filtration rate. To date, three different loci have been identified, on chromosomes 1, 17 and 12. OBJECTIVE:To test for genetic link...

journal_title：Journal of hypertension

authors： Disse-Nicodeme S,Desitter I,Fiquet-Kempf B,Houot AM,Stern N,Delahousse M,Potier J,Ader JL,Jeunemaitre X

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence and risk markers of arterial hypertension in the context of a rapidly growing urbanization in Africa. DESIGN:A cross-sectional study was performed on a representative sample of inhabitants of Pikine, an urban suburb of Dakar, Senegal. METHODS:Blood pressure was measured by properly ...

journal_title：Journal of hypertension

authors： Astagneau P,Lang T,Delarocque E,Jeannee E,Salem G

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) recovery after orthostatic hypotension might be important to prevent cerebral hypoperfusion episodes in older adults, and be related to better clinical outcome. The objective was to study the relationship between BP recovery and clinical outcome, that is physical and cognitive performance,...

journal_title：Journal of hypertension

authors： Mol A,Slangen LRN,van Wezel RJA,Maier AB,Meskers CGM

更新日期：2021-01-01 00:00:00

abstract：:Interstrain restriction fragment length polymorphism was detected after Southern blot hybridization of spontaneously hypertensive (SHR) and control (WKY) rat DNA digested by Bam HI restrictase with a v-fos probe. The SHR genome was characterized by an additional minor band of 4.0 kb. Other restriction fragment length ...

journal_title：Journal of hypertension

authors： Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

更新日期：1988-10-01 00:00:00

abstract：:Predictive value of arterial stiffness in cardiovascular disease has been recognized for many decades. Carotid-femoral pulse wave velocity (cfPWV), as a noninvasive measurement, has been recommended as a gold standard of arterial stiffness, and we believe that this surrogate of arterial stiffness has been refined to t...

journal_title：Journal of hypertension

authors： Zhang Y,Agnoletti D,Xu Y,Wang JG,Blacher J,Safar ME

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that genetically determined alterations of maternal immune tolerance to a foetal semi-allograft are important for the pathogenesis of hypertensive disorders in pregnancy. DESIGN:A genetic association study was performed to analyse the impact of genetic polymorphisms known to be involve...

journal_title：Journal of hypertension

authors： Pfab T,Chen YP,Slowinski T,Richter CM,Godes M,Arck PC,Halle H,Hocher B

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients. DESIGN:A pragmatic randomized, controlled trial. SETTING:Hypertension clinic of a university hospital. PATIENTS:Hypertensive patients aged 18...

journal_title：Journal of hypertension

authors： Bloch KV,Salles GF,Muxfeldt ES,Da Rocha Nogueira A

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:We examined the effects of a calcium antagonist and an angiotensin converting enzyme (ACE) inhibitor on contractile and non-contractile protein metabolism and cardiac function in a monocrotaline-induced right ventricular hypertrophy model, in order to define the effects of these drugs on cardiac hypertrophy. ...

journal_title：Journal of hypertension

authors： Tanaka K,Honda M,Kuramochi T,Hashimoto M,Masumura S,Mansoor AM,Ishikawa S,Morioka S

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome is associated with a high risk of cardiovascular disease in hypertension. We evaluated whether metabolic syndrome is associated with early vascular alterations, such as increased peripheral wave reflections and endothelial dysfunction, in untreated essential hypertensive patients. METHODS:...

journal_title：Journal of hypertension

authors： Plantinga Y,Ghiadoni L,Magagna A,Giannarelli C,Penno G,Pucci L,Taddei S,Del Prato S,Salvetti A

更新日期：2008-06-01 00:00:00

abstract：:: Primary aldosteronism is a frequent cause of secondary hypertension requiring a specific pharmacological treatment with mineralocorticoid receptor antagonist or with unilateral adrenalectomy. These treatments have shown to reduce the excess of cardiovascular risk characteristically associated with this disease. In p...

journal_title：Journal of hypertension

authors： Mulatero P,Sechi LA,Williams TA,Lenders JWM,Reincke M,Satoh F,Januszewicz A,Naruse M,Doumas M,Veglio F,Wu VC,Widimsky J

更新日期：2020-06-25 00:00:00

abstract：OBJECTIVE:To test the hypothesis that insulin differently modifies vasoconstriction and recovery from vasoconstriction induced by endogenously released versus circulating norepinephrine, and to investigate the time-dependency of its effect METHODS:Healthy male subjects were studied. Norepinephrine was infused for 10 m...

journal_title：Journal of hypertension

authors： van Veen S,Chang PC

更新日期：1998-08-01 00:00:00