Interstrain restriction fragment length polymorphism of c-fos and c-src oncogene loci in spontaneously hypertensive and normotensive rats.

abstract：BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...

journal_title：Journal of hypertension

authors： Lago RM,Pencina MJ,Wang TJ,Lanier KJ,D'Agostino RB,Kannel WB,Vasan RS

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Renal denervation (RDN) can reduce sympathetic activity and blood pressure (BP) in patients with hypertension. The effects on resting and ambulatory heart rate (HR), also regulated by the sympathetic nervous system, are not established. METHODS:Herein, we report 12-month outcomes from the Global SYMPLICITY ...

journal_title：Journal of hypertension

authors： Böhm M,Ukena C,Ewen S,Linz D,Zivanovic I,Hoppe U,Narkiewicz K,Ruilope L,Schlaich M,Negoita M,Schmieder R,Williams B,Zeymer U,Zirlik A,Mancia G,Mahfoud F,Global SYMPLICITY Registry Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the prevalence and distribution of hypertension and to determine the status of hypertension awareness, treatment and control in the Portuguese adult population. METHODS:This study was conducted in 2003, and a multistage cluster sampling method was used to select a...

journal_title：Journal of hypertension

authors： Macedo ME,Lima MJ,Silva AO,Alcantara P,Ramalhinho V,Carmona J

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To investigate the role of the renal medulla in early hypertension in spontaneously hypertensive rats (SHR), and to explore whether the attenuated increase of pressure induced by enalapril treatment is affected by chemical medullectomy. DESIGN:Forty-four male SHR were studied from 5 to 18 weeks of age: 22 re...

journal_title：Journal of hypertension

authors： Bergström G,Bohman SO,Folkow B,Göthberg G,Rudenstam J,Karlström G

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP)-lowering trials studying efficacy mostly assesses binary outcome events, for example stroke/no stroke. Analysis of ordered categorical vascular events (e.g. three levels: fatal stroke/nonfatal stroke/no stroke) provides information on severity and is more powerful statistically than analy...

journal_title：Journal of hypertension

authors： Geeganage CM,Tracy M,Bath MW,Bath PM

更新日期：2010-10-01 00:00:00

abstract：:The benefit of blood pressure-lowering therapy in individuals with normal blood pressure who are at high cardiovascular risk creates a challenge in how best to advocate such therapy. Arguments based on a putative causal role for blood pressure and the need to reduce blood pressure may be less likely to succeed than ar...

journal_title：Journal of hypertension

authors： Campbell DJ

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE(S):To study the changes in macrophage inducible nitric oxide synthase (iNOS) activity, plasma levels of nitrite, lipid peroxidation (LPO) and melatonin in human essential hypertension before and 6 months after 4 mg/day lacidipine treatment. DESIGN:The study was carried out in a total of 25 subjects--11 healt...

journal_title：Journal of hypertension

authors： Escames G,Khaldy H,León J,González L,Acuña-Castroviejo D

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:There have been very few studies on life prognosis of cardiovascular disease according to blood pressure stratification in the Japanese. Therefore, in Japan, although treatment of hypertension is possible, albeit at times difficult, due to the availability of various antihypertensive medications, the appropr...

journal_title：Journal of hypertension

authors： Takagi S,Saitoh S,Nakano M,Hayashi Y,Obara F,Onishi H,Shimamoto K

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:To establish whether safety and feasibility of dobutamine and dipyridamole stress echocardiography are affected by history of hypertension. METHODS:Data on 2200 consecutive pharmacologic stress echocardiography (959 dobutamine and 1241 dipyridamole) performed between October 1990 and February 2001 at a sing...

journal_title：Journal of hypertension

authors： Cortigiani L,Zanetti L,Bigi R,Desideri A,Fiorentini C,Nannini E

更新日期：2002-07-01 00:00:00

abstract：:Reduced nitric oxide bioavailability contributes to endothelial dysfunction and hypertension. The endothelial isoform of nitric oxide synthase (eNOS) is responsible for the production of nitric oxide within the endothelium. Loss of eNOS cofactor tetrahydrobiopterin to initial increase in oxidative stress leads to unco...

journal_title：Journal of hypertension

authors： Li Q,Youn JY,Cai H

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...

journal_title：Journal of hypertension

authors： van de Borne P,Schintgen M,Niset G,Schoenfeld P,Nguyen H,Degré S,Degaute JP

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) load, defined as the percentage of abnormally elevated BP readings, is usually provided on the report of ambulatory BP monitoring. However, the usefulness of BP load is still uncertain. In the present study, we examined whether BP load would be associated, independently of BP level, with t...

journal_title：Journal of hypertension

authors： Liu M,Li Y,Wei FF,Zhang L,Han JL,Wang JG

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To study the effect of oral magnesium supplementation on blood pressure, platelet aggregation and platelet calcium handling in deoxycorticosterone acetate (DOCA)-induced hypertension in rats. DESIGN AND METHODS:Rats were divided into four groups of 20 each. Drug treatments were given for a 6-week period. Con...

journal_title：Journal of hypertension

authors： Kh R,Khullar M,Kashyap M,Pandhi P,Uppal R

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Telmisartan is a unique AT1 receptor blocker with a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonistic action. Activation of PPAR-gamma could prevent inflammation and brain damage. METHOD:We investigated the beneficial effect of telmisartan on ischemic brain damage via PPAR-gamma activa...

journal_title：Journal of hypertension

authors： Iwanami J,Mogi M,Tsukuda K,Min LJ,Sakata A,Jing F,Iwai M,Horiuchi M

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:It has been shown that nitric oxide (NO) plays an important role in the central control of arterial pressure and sympathetic nerve activity. The aim of this study was to determine whether NO can regulate sympathetic nerve activity by an action on pressor neurons within the rostral part of the ventrolateral me...

journal_title：Journal of hypertension

authors： Hirooka Y,Polson JW,Dampney RA

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

journal_title：Journal of hypertension

authors： Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

更新日期：2006-06-01 00:00:00

abstract：:The haemodynamic effects associated with the onset of hypertension induced by infusion of adrenocorticotrophin (ACTH) were investigated in sheep. Analysis of haemodynamic data collected over 24 h by a computer-based monitoring system revealed that mean arterial pressure (MAP) was significantly increased after 4 h. Car...

journal_title：Journal of hypertension

authors： Spence CD,Brown A,Coghlan JP,Parkes DG,Whitworth JA,Scoggins BA

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE AND DESIGN:The aim of the study was to assess the role of angiotensin II (Ang II) in the maintenance of cardiovascular hypertrophy and the abnormal vascular amplifier properties in spontaneously hypertensive rats (SHR) with established hypertension. Losartan, a type 1 Ang II receptor antagonist, was administe...

journal_title：Journal of hypertension

authors： Oddie CJ,Dilley RJ,Kanellakis P,Bobik A

更新日期：1993-07-01 00:00:00

abstract：:An index of peripheral vascular resistance, derived from directly measured arterial pressure, has been developed and tested in an animal model. Assuming a mono-exponential character for diastole, the time constant for direct arterial pressure decay in the central aorta was obtained with high-fidelity recording techniq...

journal_title：Journal of hypertension

authors： Walsh JT,Mehta SK,Topham WS,Goldberg AD

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To follow the changes in blood pressure and echocardiographically determined left ventricular mass in offspring of mothers who had hypertension during pregnancy. DESIGN:Longitudinal study with a 5-year follow-up. METHODS:Nineteen offspring of mothers who had hypertension during pregnancy, and sustained hype...

journal_title：Journal of hypertension

authors： Himmelmann A,Svensson A,Hansson L

更新日期：1994-01-01 00:00:00

abstract：INTRODUCTION:Abnormalities of calcium metabolism independent of changes in intracellular calcium have been described in patients with essential hypertension. These include increased urinary calcium excretion for a given salt intake, a raised parathyroid hormone level, an increase in urinary cyclic AMP, a tendency for a...

journal_title：Journal of hypertension

authors： MacGregor GA,Cappuccio FP

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:Construction of prognostically relevant endpoints for clinical trials in hypertension has increasingly included coronary revascularization with myocardial infarction (MI) as manifestations of coronary artery disease. However, whether coronary revascularization and MI predict other cardiovascular events simila...

journal_title：Journal of hypertension

authors： Cicala S,de Simone G,Gerdts E,Dahlöf B,Lindholm LH,Kjeldsen SE,Devereux RB

更新日期：2010-06-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:To determine the blood pressure responses in elderly normotensive men and women to dietary sodium and to the diunsaturated fatty acid dihomogammalinolenic acid (DGLA), which is derived from linoleic acid. DESIGN:Blood pressure responses were assessed in 66 subjects (36 male, 30 female; mean age 65 years) on ...

journal_title：Journal of hypertension

authors： Nestel PJ,Clifton PM,Noakes M,McArthur R,Howe PR

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:Hypertension is a major risk factor for cardiovascular disease. Polymorphism in the beta2-adrenergic receptor (ADRB2) and nitric oxide synthase 3 (NOS3) genes is associated with clinical cardiovascular phenotypes. The Arg16Gly and Glu298Asp polymorphisms of ADRB2 and NOS3 genes, respectively, have been report...

journal_title：Journal of hypertension

authors： Misono M,Maeda S,Iemitsu M,Nakata Y,Otsuki T,Sugawara J,Zempo H,Yoshizawa M,Miyaki A,Kuno S,Matsuda M,Ajisaka R

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To estimate the compliance rate and associated factors among a population of hypertensive subjects registered in hospitals and primary health care centres. DESIGN:A prospective study carried out on a sample of hypertensive subjects. METHOD:Compliance with treatment by the study sample was measured using the...

journal_title：Journal of hypertension

authors： Khalil SA,Elzubier AG

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS:Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carr...

journal_title：Journal of hypertension

authors： Czernichow S,Castetbon K,Salanave B,Vernay M,Barry Y,Batty GD,Hercberg S,Blacher J

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of cyclosporine A (CsA; Sandimmun Neoral) on systemic and renal hemodynamics, tubular function, and sodium excretion in healthy volunteers. Furthermore, we studied whether CsA enhances the systemic and renal hemodynamic sensitivity to norepinephrine. METHODS:Eighteen healthy volunte...

journal_title：Journal of hypertension

authors： Hansen JM,Fogh-Andersen N,Christensen NJ,Strandgaard S

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The difference between clinic and ambulatory blood pressure (BP) is a poor estimate of the true white-coat effect (WCE) measured with beat-to-beat recording. METHOD:We investigated whether the difference between clinic and home BP (home WCE) was a better estimate of true WCE than ambulatory WCE. In 73 young...

journal_title：Journal of hypertension

authors： Saladini F,Benetti E,Malipiero G,Casiglia E,Palatini P

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Exercise training has antihypertensive and renoprotective effects in humans and rats. However, the effects of exercise training on renal disorders that occur with salt-sensitive hypertension remains unclear. The study aim was to investigate the effects and mechanisms of exercise training on renal function in ...

journal_title：Journal of hypertension

authors： Ogawa Y,Takahashi J,Sakuyama A,Xu L,Miura T,Muroya Y,Ito D,Kohzuki M,Ito O

更新日期：2020-07-01 00:00:00