Changes in iNOS activity, oxidative stress and melatonin levels in hypertensive patients treated with lacidipine.

abstract：OBJECTIVES:This controlled trial assessed the effect of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH). METHODS:We evaluated 96 patients with resistant hypertension, defined as clinic BP at least 140/90 mmHg despite treat...

journal_title：Journal of hypertension

authors： Lozano L,Tovar JL,Sampol G,Romero O,Jurado MJ,Segarra A,Espinel E,Ríos J,Untoria MD,Lloberes P

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To determine whether obese hypertensive patients manifest a diminished regional vasodilator response to an oral glucose challenge. METHODS:Nineteen obese hypertensives (body mass index 34.1 +/- 1.3 kg/m2, blood pressure 144 +/- 3/96 +/- 2 mmHg) and 13 lean controls (23.6 +/- 0.3 kg/m2, 127 +/- 4/83 +/- 3 mmH...

journal_title：Journal of hypertension

authors： Egan BM,Stepniakowski K

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To compare estimates of mean population salt intake in North and South India derived from spot urine samples versus 24-h urine collections. METHODS:In a cross-sectional survey, participants were sampled from slum, urban and rural communities in North and in South India. Participants provided 24-h urine colle...

journal_title：Journal of hypertension

authors： Petersen KS,Johnson C,Mohan S,Rogers K,Shivashankar R,Thout SR,Gupta P,He FJ,MacGregor GA,Webster J,Santos JA,Krishnan A,Maulik PK,Reddy KS,Gupta R,Prabhakaran D,Neal B

更新日期：2017-11-01 00:00:00

abstract：:We have previously reported that pressor doses of angiotensin II induce atrial natriuretic factor (ANF) release. Since the number of glomerular and vascular ANF receptors may vary inversely with plasma ANF levels, we investigated whether they are modified by angiotensin II. Male rats were infused intraperitoneally for...

journal_title：Journal of hypertension

authors： Gauquelin G,Schiffrin EL,Garcia R

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVES:We assessed the prevalence and determinants of high blood pressure (BP), and barriers to diagnosis and treatment, in Dar es Salaam, Tanzania. METHODS:We surveyed and screened 2174 community-dwelling adults aged at least 40 years in 2014 and conducted a follow-up after 1 year. RESULTS:Median BP was 131/81 m...

journal_title：Journal of hypertension

authors： Zack RM,Irema K,Kazonda P,Leyna GH,Liu E,Spiegelman D,Fawzi W,Njelekela M,Killewo J,Danaei G

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:To investigate whether the combination of exercise training with the angiotensin-converting enzyme inhibitor lisinopril will have an additional beneficial effect on left ventricular function in spontaneously hypertensive rats. DESIGN:Twelve-week-old male rats were assigned to treadmill running (Ht-Ex; 20 m/...

journal_title：Journal of hypertension

authors： Ziada AM

更新日期：2009-06-01 00:00:00

abstract：:Predictive value of arterial stiffness in cardiovascular disease has been recognized for many decades. Carotid-femoral pulse wave velocity (cfPWV), as a noninvasive measurement, has been recommended as a gold standard of arterial stiffness, and we believe that this surrogate of arterial stiffness has been refined to t...

journal_title：Journal of hypertension

authors： Zhang Y,Agnoletti D,Xu Y,Wang JG,Blacher J,Safar ME

更新日期：2014-08-01 00:00:00

abstract：:The binding of 125I-angiotensin II to human blood cells was investigated. Blood was drawn from healthy volunteers and platelets prepared with minimal contamination of red cells and white blood cells (less than 0.1%). Using thin layer chromatography, degradation of 125I-angiotensin II by platelets could be demonstrated...

journal_title：Journal of hypertension

authors： Mann JF,Sis J,Ritz E

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to assess the regression of left ventricular hypertrophy (LVH) during antihypertensive treatment, and its relationship with the changes in microalbuminuria. INDIVIDUALS AND METHODS:One hundred and sixty-eight previously untreated patients with echocardiographic LVH, 46 ...

journal_title：Journal of hypertension

authors： Rodilla E,Pascual JM,Costa JA,Martin J,Gonzalez C,Redon J

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To study the association between polymorphisms in the angiotensin converting enzyme (ACE) gene and angiotensinogen (AGT) gene and hypertension and/or type 2 diabetes in a community population. PATIENTS AND METHODS:The insertion (I)/deletion (D) polymorphism of the ACE gene and the M235T polymorphism of the A...

journal_title：Journal of hypertension

authors： Bengtsson K,Orho-Melander M,Lindblad U,Melander O,Bøg-Hansen E,Ranstam J,Råstam L,Groop L

更新日期：1999-11-01 00:00:00

abstract：:Hypertension is the most prevalent chronic medical condition and a major risk factor for cardiovascular morbidity and mortality. In the majority of hypertensive cases, the underlying cause of hypertension cannot be easily identified because of the heterogeneous, polygenic and multi-factorial nature of hypertension. Me...

journal_title：Journal of hypertension

authors： Nikolic SB,Sharman JE,Adams MJ,Edwards LM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations. The aim of this study was to evaluate the impact of aldosterone excess on the development of such complications, and the effects of surgical and pharmacological treatment on their long-term outcome. METH...

journal_title：Journal of hypertension

authors： Giacchetti G,Ronconi V,Turchi F,Agostinelli L,Mantero F,Rilli S,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：:Uptake of 45Ca was measured in rings of thoracic aorta from rabbits with hypertension, induced by cellophane perinephritis (Page hypertension: one-kidney, one wrap). Basal 45Ca uptake was increased significantly in the hypertensive group (sham: 100 +/- 3, hypertensive: 133 +/- 11 nmol/g wet weight, n = 6). 45Ca uptake...

journal_title：Journal of hypertension

authors： Dong Y,Wadsworth RM

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:This study was designed to evaluate the capacity of norepinephrine (NE) to induce hypertrophic remodeling of small arteries in rats, and to determine the involvement of endothelin (ET) to initiate and maintain it. DESIGN AND RESULTS:Treatment with NE (2.5 microg/kg per min) for 14 or 28 days produced a simil...

journal_title：Journal of hypertension

authors： Dao HH,Martens FM,Larivière R,Yamaguchi N,Cernacek P,de Champlain J,Moreau P

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...

journal_title：Journal of hypertension

authors： Lago RM,Pencina MJ,Wang TJ,Lanier KJ,D'Agostino RB,Kannel WB,Vasan RS

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:This study analyzed regional differences in blood pressure (BP) distribution and management in Germany 2008-2011 in a nationwide study. METHODS:The analyses were based on standardized BP measurements and anatomical therapeutic chemical classification-coded medication from the population-based German Health I...

journal_title：Journal of hypertension

authors： Diederichs C,Neuhauser H

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the utility of the generalized transfer function (GTF) and the late systolic shoulder of the radial pressure waveform (SBP2) for estimating seated central systolic blood pressure (c-SBP) and seated c-augmentation index (c-AIx). METHODS:In 199 participants (182 cardiovasc...

journal_title：Journal of hypertension

authors： Hirata K,Kojima I,Momomura S

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate whether adjustment for frailty influences the relationship of blood pressure with mortality in elderly patients with type 2 diabetes mellitus (T2DM). METHODS:Patients aged 60 years and older (n = 858) were selected from a prospective observational cohort study of primary care patients...

journal_title：Journal of hypertension

authors： van Hateren KJ,Hendriks SH,Groenier KH,Bakker SJ,Bilo HJ,Kleefstra N,Landman GW

更新日期：2015-06-01 00:00:00

abstract：:Recent investigations have delineated the renal microvascular responsiveness to pressure, by using isolated afferent arterioles, juxtamedullary nephrons, and isolated perfused hydronephrotic kidneys. Both afferent arterioles and interlobular arteries (ILA) manifest pressure-dependent vasoconstrictor responses to eleva...

journal_title：Journal of hypertension

authors： Hayashi K,Epstein M,Saruta T

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Apoptosis or programmed cell death could be greater than normal in various cardiovascular disorders, particularly in the heart. Apoptosis might contribute to remodeling of blood vessels in hypertension and could participate in regulation of vascular hypertrophy/hyperplasia. OBJECTIVE:To investigate apoptosi...

journal_title：Journal of hypertension

authors： Sharifi AM,Schiffrin EL

更新日期：1997-12-01 00:00:00

abstract：AIMS:The addition of an aldosterone receptor antagonist on top of current optimal therapy (based on angiotensin II inhibition) has demonstrated an important clinical benefit in heart failure patients with systolic dysfunction. Whether this finding also applies to heart failure patients with preserved systolic function ...

journal_title：Journal of hypertension

authors： Muñoz-Pacheco P,Ortega-Hernández A,Caro-Vadillo A,Casanueva-Eliceiry S,Aragoncillo P,Egido J,Fernández-Cruz A,Gómez-Garre D

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence and associated risks of white-coat hypertension (WCH) are still a matter of debate. We aimed to assess differences in prevalence and associated conditions of WCH defined on the basis of the normality of all daytime, night-time, and 24-h blood pressure (BP), only daytime, or only 24-h B...

journal_title：Journal of hypertension

authors： de la Sierra A,Vinyoles E,Banegas JR,Segura J,Gorostidi M,de la Cruz JJ,Ruilope LM

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:In short-term feeding trials, replacement of other macronutrients with monounsaturated fatty acid reduces blood pressure. However, observational studies have not clearly demonstrated a relationship between monounsaturated fatty acid intake and blood pressure. We report associations of monounsaturated fatty ac...

journal_title：Journal of hypertension

authors： Miura K,Stamler J,Brown IJ,Ueshima H,Nakagawa H,Sakurai M,Chan Q,Appel LJ,Okayama A,Okuda N,Curb JD,Rodriguez BL,Robertson C,Zhao L,Elliott P,INTERMAP Research Group.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine the blood pressure responses in elderly normotensive men and women to dietary sodium and to the diunsaturated fatty acid dihomogammalinolenic acid (DGLA), which is derived from linoleic acid. DESIGN:Blood pressure responses were assessed in 66 subjects (36 male, 30 female; mean age 65 years) on ...

journal_title：Journal of hypertension

authors： Nestel PJ,Clifton PM,Noakes M,McArthur R,Howe PR

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Some patients with essential hypertension manifest greater than normal urinary excretion of albumin (UAE). Authors of a few retrospective studies have suggested that there is an association between microalbuminuria and cardiovascular risk. OBJECTIVE:To evaluate whether microalbuminuria is associated with a ...

journal_title：Journal of hypertension

authors： Bigazzi R,Bianchi S,Baldari D,Campese VM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Genome-wide scans from Italy and China suggest a hypertension-susceptible locus between D2S2278 (nucleotides 11,245,080 - 11,245,358) and D2S168 (nucleotides 11,467,214 - 11,467,422) on chromosome 2. METHODS:We performed a large association study of polymorphisms in this region with blood pressure modulatio...

journal_title：Journal of hypertension

authors： Kamide K,Kokubo Y,Yang J,Tanaka C,Hanada H,Takiuchi S,Inamoto N,Banno M,Kawano Y,Okayama A,Tomoike H,Miyata T

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:Many different stress echocardiographic and radionuclide perfusion imaging tests have been proposed for detecting epicardial coronary artery disease (CAD) in hypertensive patients. Their relative diagnostic and prognostic value has not been exactly established. BACKGROUND:A positive exercise electrocardiogr...

journal_title：Journal of hypertension

authors： Astarita C,Pálinkás A,Nicolai E,Maresca FS,Varga A,Picano E

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion. METHODS:Estimates of attributable burden were made using population impact fractions, which used data on mean systolic blood pressure levels, dise...

journal_title：Journal of hypertension

authors： Lawes CM,Vander Hoorn S,Law MR,Elliott P,MacMahon S,Rodgers A

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Cardiovascular risk prediction is deemed fundamental and the assessment of organ damage is emerging as a potentially 'downstream' picture of individual risk. Our aim was to assess the feasibility and value of prediction of coronaropathy [coronary artery disease (CAD)] of integrated cardiovascular ultrasound e...

journal_title：Journal of hypertension

authors： Moreo A,Gaibazzi N,Faggiano P,Mohammed M,Carerj S,Mureddu G,Pigazzani F,Muiesan L,Salvetti M,Cesana F,Faden G,Facchetti R,Giannattasio C,Rigo F

更新日期：2015-06-01 00:00:00