Carotid-femoral pulse wave velocity in the elderly.

abstract：OBJECTIVE:Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolo...

journal_title：Journal of hypertension

authors： Brooksby P,Levi AJ,Jones JV

更新日期：1993-06-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinica...

journal_title：Journal of hypertension

authors： Grassi G,Seravalle G,Maloberti A,Facchetti R,Cuspidi C,Bombelli M,Laurent S,Redon J,Mancia G

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between endothelin-1 (ET-1), human atrial natriuretic peptide (hANP), plasma-renin activity (PRA) and 24-h urinary excretion of aldosterone (U-Ald) in pregnancy-induced hypertension (PIH). DESIGN AND METHODS:Plasma hANP (pg/ml), ET-1 (pg/ml), PRA (ng/ml per h) and U-Ald (microg/...

journal_title：Journal of hypertension

authors： Zafirovska KG,Maleska VT,Bogdanovska SV,Lozance LA,Masin-Paneva J,Gerasimovska BD

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:When assessing arterial stiffness, heart rate (HR) and blood pressure (BP) are potential confounders. It appears that the HR/BP dependences of pulse wave velocity (PWV) and distensibility are different, even though both assess arterial stiffness. This study aims to compare aortic PWV as measured using pulse ...

journal_title：Journal of hypertension

authors： Spronck B,Tan I,Reesink KD,Georgevsky D,Delhaas T,Avolio AP,Butlin M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Blood pressure management is a key issue among patients with coronary heart disease (CHD). The present study aimed to identify particular patient groups that may need to be specifically targeted in secondary prevention of CHD. METHODS:EUROASPIRE III is a cross-sectional study conducted in 2006-2007 among pa...

journal_title：Journal of hypertension

authors： Prugger C,Keil U,Wellmann J,de Bacquer D,de Backer G,Ambrosio GB,Reiner Z,Gaita D,Wood D,Kotseva K,Heidrich J,EUROASPIRE III Study Group.

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the noradrenergic sympathetic hyperinnervation in the spontaneously hypertensive rat (SHR), a genetic model of essential hypertension, is associated with changes in neurotrophin 3 (NT3) concentrations. METHODS:NT3 levels were measured using a sensitive enzyme-linked immunosorbent assay (...

journal_title：Journal of hypertension

authors： Zhang SH,Rush RA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:The L/N-type calcium channel blocker (CCB) cilnidipine suppresses sympathetic nerve activity and has a superior renoprotective effect compared with L-type CCBs such as amlodipine. The cardioprotective action of cilnidipine has remained largely uncharacterized, however. We have now investigated the effects of ...

journal_title：Journal of hypertension

authors： Takatsu M,Hattori T,Murase T,Ohtake M,Kato M,Nashima K,Nakashima C,Takahashi K,Ito H,Niinuma K,Aritomi S,Murohara T,Nagata K

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

journal_title：Journal of hypertension

authors： Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND METHOD:This study evaluated the effects of a linear block strength training programme on the parameters of cardiac remodelling in spontaneously hypertensive rats. Thirty-nine rats were equally distributed in four groups: normotensive sedentary, normotensive trained, hypertensive sedentary and hypertensiv...

journal_title：Journal of hypertension

authors： Perilhão MS,Krause Neto W,da Silva AA,Alves LLS,Antonio EL,Medeiros A,Rica RL,Serra AJ,Tucci PJF,Bocalini DS

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Night-time blood pressure (BP) - prognostically more important than circadian BP variability - has not been evaluated for quantitative associations with objective sleep quality in large populations. METHODS:The cross-sectional study measured actigraphic sleep parameters and night-time BP for two nights in 1...

journal_title：Journal of hypertension

authors： Oume M,Obayashi K,Asai Y,Ogura M,Takeuchi K,Tai Y,Kurumatani N,Saeki K

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To compare the prediction of mortality by ambulatory blood pressure monitoring and screening blood pressure measurements in a general population. DESIGN:A prospective cohort study. PATIENTS AND METHODS:We obtained blood pressure data for 1542 subjects (565 men and 977 women) aged > or = 40 years who were fo...

journal_title：Journal of hypertension

authors： Ohkubo T,Imai Y,Tsuji I,Nagai K,Watanabe N,Minami N,Itoh O,Bando T,Sakuma M,Fukao A,Satoh H,Hisamichi S,Abe K

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Lacidipine is a widely used calcium-channel blocker, which has both long-lasting antihypertensive activity and also antioxidant properties. Previous studies have demonstrated the ability of lacidipine to reduce the development of atherosclerotic lesions in several animal models. OBJECTIVE:The present study ...

journal_title：Journal of hypertension

authors： Cristofori P,Lanzoni A,Quartaroli M,Pastorino AM,Zancanaro C,Cominacini L,Gaviraghi G,Turton J

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:The relationship between sodium intake and cardiovascular events is controversial, but most large epidemiological studies estimated sodium intake using formulae based on single urine samples, the validity of which is debated. We evaluated sodium intake estimating formulae in a large cohort of adult patients. ...

journal_title：Journal of hypertension

authors： Vidal-Petiot E,Joseph A,Resche-Rigon M,Boutten A,Mullaert J,d' Ortho MP,Vrtovsnik F,Steg PG,Flamant M

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE AND DESIGN:The early phase of weight loss induced by fasting is associated with diuresis, natriuresis and reduction in blood pressure through unclear mechanisms. Atrial natriuretic peptide (ANP) is a cardiac hormone with potent natriuretic, diuretic and hypotensive effects mediated by 'biologically active' re...

journal_title：Journal of hypertension

authors： Sarzani R,Paci VM,Zingaretti CM,Pierleoni C,Cinti S,Cola G,Rappelli A,Dessì-Fulgheri P

更新日期：1995-11-01 00:00:00

abstract：AIMS:Selenium is an antioxidant micronutrient with potential associations with hypertension. Few studies have investigated the association of serum selenium concentrations with blood pressure and hypertension in countries with low dietary selenium intake such as Germany, with inconsistent findings. METHODS:We undertoo...

journal_title：Journal of hypertension

authors： Berthold HK,Michalke B,Krone W,Guallar E,Gouni-Berthold I

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Genetic variants that influence large conductance calcium-activated potassium channel's function may alter arterial function and contribute to the known heritability of arterial stiffness and blood pressure. The beta1-subunit (KCNMB1) of the large conductance calcium-activated potassium channel includes two ...

journal_title：Journal of hypertension

authors： Kelley-Hedgepeth A,Peter I,Montefusco MC,Levy D,Benjamin EJ,Vasan RS,Mendelsohn ME,Housman D,Huggins GS,Mitchell GF

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:We evaluated the predictive power of home blood pressure and clinic blood pressure based on the long-term cardiovascular outcome in hypertensive patients with and without impaired glucose metabolism (IGM). METHOD:The multicentre Hypertension Objective Treatment Based on Measurement by Electrical Devices Blo...

journal_title：Journal of hypertension

authors： Noguchi Y,Asayama K,Staessen JA,Inaba M,Ohkubo T,Hosaka M,Satoh M,Kamide K,Awata T,Katayama S,Imai Y,HOMED-BP study group.

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:Several studies have shown lower carotid-femoral pulse wave velocity (cfPWV) levels in women compared to men, a difference that could partially explain the increased longevity in women. However, these studies have been performed in industrial countries while few data are available in emerging populations. We...

journal_title：Journal of hypertension

authors： Temmar M,Watfa G,Joly L,Kearney-Schwartz A,Youcef M,Bensalah S,Mustapha Y,Salvi P,Gautier S,Safar M,Labat C,Benetos A

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:We attempted to determine a valid pharmacological approach for the control of high blood pressure in obese hypertensive patients using two antihypertensive agents with different pharmacological actions. DESIGN:Thirty-two obese hypertensive black women were randomly treated with chlorthalidone or clonidine to...

journal_title：Journal of hypertension

authors： Reisin E,Weed SG

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVES:The genes responsible for obesity are also candidate genes for obesity-related conditions, such as hypertension and type 2 diabetes. A functional polymorphism in the uncoupling protein 2 (UCP2) promoter has been reported to be associated with obesity in Caucasians. To clarify the contribution of this polymor...

journal_title：Journal of hypertension

authors： Ji Q,Ikegami H,Fujisawa T,Kawabata Y,Ono M,Nishino M,Ohishi M,Katsuya T,Rakugi H,Ogihara T

更新日期：2004-01-01 00:00:00

abstract：:Hypertension is associated with thickening of the wall of resistance vessels, but the cellular or genetic basis of this is unclear. Cell proliferation and intracellular alkalinization via increased Na+/H+ exchange are linked in the response of tissues to growth factors. To define a possible cellular basis for vascular...

journal_title：Journal of hypertension

authors： Ng LL,Dudley C,Bomford J,Hawley D

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis in the two-kidney, o...

journal_title：Journal of hypertension

authors： Vethe H,Finne K,Skogstrand T,Vaudel M,Vikse BE,Hultström M,Placier S,Scherer A,Tenstad O,Marti HP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The mechanism of the association between obesity and hypertension is not clear. The recently discovered obese gene product, leptin, the levels of which increase in obese subjects, has been shown to reduce food intake and increase sympathetic nervous system activity in animal studies. The present study was und...

journal_title：Journal of hypertension

authors： Hirose H,Saito I,Tsujioka M,Mori M,Kawabe H,Saruta T

更新日期：1998-12-01 00:00:00

abstract：:Experimental models of genetic hypertension are used to develop paradigms to study human essential hypertension while removing some of the complexity inherent in the study of human subjects. Since 1991 several quantitative trait loci responsible for blood pressure regulation have been identified in various rat crosses...

journal_title：Journal of hypertension

authors： Dominiczak AF,Clark JS,Jeffs B,Anderson NH,Negrin CD,Lee WK,Brosnan MJ

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that qualitative microalbuminuria (MAU) screening in a practice setting would identify non-diabetic hypertensive patients at high risk of developing cardiovascular disease. DESIGN:We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and...

journal_title：Journal of hypertension

authors： Agrawal B,Berger A,Wolf K,Luft FC

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Abnormal vascular reactivity contributes to the pathophysiology of hypertension and hypertension-related organ damage. As the dietary content of fatty acids may affect the vascular responses, we investigated the relationship of endothelium-independent and endothelium-dependent vasodilation with the fatty acid...

journal_title：Journal of hypertension

authors： Colussi G,Catena C,Dialti V,Mos L,Sechi LA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Mechanisms involved in hypertension in homozygous mice for the defective endothelial nitric oxide synthase gene (eNOS-/-) have not been fully elucidated. As NO is a potent vasodilator agent and possibly promotes angiogenesis, we investigated whether vasoconstriction and/or microvascular rarefaction could exp...

journal_title：Journal of hypertension

authors： Kubis N,Richer C,Domergue V,Giudicelli JF,Lévy BI

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between birth characteristics and blood pressure at age 20 years and to assess whether effects of birth weight on blood pressure are amplified from childhood to adulthood. DESIGN:A longitudinal study of 584 men and women from Adelaide, Australia, examined previously at 8 years an...

journal_title：Journal of hypertension

authors： Moore VM,Cockington RA,Ryan P,Robinson JS

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Cathepsin L (CTSL1) catalyzes the formation of peptides that influence blood pressure (BP). Naturally occurring genetic variation or targeted ablation of the Ctsl1 locus in mice yield cardiovascular pathology. Here, we searched for genetic variation across the human CTSL1 locus and probed its functional effe...

journal_title：Journal of hypertension

authors： Mbewe-Campbell N,Wei Z,Zhang K,Friese RS,Mahata M,Schork AJ,Rao F,Chiron S,Biswas N,Kim HS,Mahata SK,Waalen J,Nievergelt CM,Hook VY,O'Connor DT

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:It has been shown that nitric oxide (NO) plays an important role in the central control of arterial pressure and sympathetic nerve activity. The aim of this study was to determine whether NO can regulate sympathetic nerve activity by an action on pressor neurons within the rostral part of the ventrolateral me...

journal_title：Journal of hypertension

authors： Hirooka Y,Polson JW,Dampney RA

更新日期：1996-11-01 00:00:00