Abstract:
:The relationships between five erythrocyte cation transport systems (Na(+)-K+ pump, Na(+)-K+ cotransport, Na(+)-Li+ countertransport and Na+ and K+ passive permeabilities) and plasma lipids (total plasma cholesterol, high-density lipoprotein cholesterol and triglycerides) were investigated in 129 male adult subjects with no known history of hypertension. Na+ and K+ erythrocyte contents were also considered for their possible relationships with plasma lipids. Na(+)-K+ cotransport and passive Na+ permeability were both significantly correlated with plasma triglycerides. Conversely, no significant correlation was found between erythrocyte cation transport systems or erythrocyte cation contents and total cholesterol. These findings suggest that plasma lipids can modulate erythrocyte ion transport activity in the general population.
journal_name
J Hypertensjournal_title
Journal of hypertensionauthors
Hajem S,Moreau T,Hannaert P,Lellouch J,Orssaud G,Huel G,Claude JR,Garay RPdoi
10.1097/00004872-199010000-00002subject
Has Abstractpub_date
1990-10-01 00:00:00pages
891-6issue
10eissn
0263-6352issn
1473-5598journal_volume
8pub_type
杂志文章abstract:OBJECTIVE:The aim of the study was to evaluate the influence of renal sympathetic nerves on the production of interleukin (IL)-6 in the kidney of normotensive Wistar rats and spontaneously hypertensive rats (SHR). DESIGN:In acute studies, the left kidney was exposed and the renal nerves were electrically stimulated to...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199305000-00004
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199303000-00013
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:To investigate the interrelationship between arrhythmias provoked by acute pressure changes, and the presence of left ventricular hypertrophy and electrolyte imbalances. DESIGN:An isolated working rat heart model was used in a prospective comparison of the effects of acute pressure changes in hypertensive an...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199202000-00010
更新日期:1992-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the prognostic significance of cardiovascular risk factors including 24-h ambulatory blood pressure level and rhythm for all-cause mortality in type 2 diabetic patients. METHODS:In a prospective observational study, 104 patients with type 2 diabetes were followed: 51 patients with diabetic nephro...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282f06428
更新日期:2007-12-01 00:00:00
abstract::Use of the aldosterone-to-renin ratio has controversially suggested that approximately 10% of hypertensives have primary aldosteronism, and most of these individuals are thought to have idiopathic hyperaldosteronism. The usual renin-angiotensin system control is intact in these individuals and is similar to that in lo...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/00004872-200201000-00003
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:Female sexual dysfunction (FSD) is increasingly attracting more scientific and public interest, and represents a poorly investigated issue in patients with essential hypertension. We evaluated the prevalence of sexual dysfunction in hypertensive women compared with normotensive women according to age, hypert...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000251898.40002.5b
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To investigate the role of an activated endothelin system in the renal dysfunction observed in chronic heart failure after myocardial infarction. METHODS:In rats with heart failure after myocardial infarction and in sham-operated animals (Sham), we investigated the effect on renal function of long-term oral ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200018100-00020
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. METHODS:A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasi...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002113
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:We tested the reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reduction in hypertensive patients. METHODS:Forty-two hypertensive patients were enrolled, and ABP monitoring (ABPM) was performed four times in each patient: twice before and twice after the treatment. Morning BP was de...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3283378477
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:It has been suggested that non-invasive aortic stiffness measurements can be used as an indicator of atherosclerosis. The relationships of arterial stiffness with arterial wall hypertrophy and atherosclerosis however, have rarely been investigated in large-scale studies. The present study reports the associat...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200201000-00013
更新日期:2002-01-01 00:00:00
abstract::BMI represents an internal metabolic and physiological environment that plays a key role in development of high blood pressure (BP) for many Americans. African-American women have a higher prevalence of high BP and being overweight than men or other ethnic groups. This study examines the genetic-environmental interact...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3283110402
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To identify predictors of pregnancy-induced hypertension and pre-eclampsia in 212 nulliparous women before 20 weeks' gestation and at approximately 28 weeks' gestation. STUDY DESIGN:A randomized, prospective study in a teaching hospital. We performed standardized measurements of systolic and diastolic arteri...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004872-199816020-00013
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND:Elevated plasma glucocorticoid level is an independent predictor of increased mortality risk in chronic heart failure, but local biosynthesis and pathophysiological roles of glucocorticoids in the heart remain unclear. METHODS:Dahl salt-sensitive rats on high-salt diet and mice with transthoracic aortic ban...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328326cb04
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Lacidipine is a widely used calcium-channel blocker, which has both long-lasting antihypertensive activity and also antioxidant properties. Previous studies have demonstrated the ability of lacidipine to reduce the development of atherosclerotic lesions in several animal models. OBJECTIVE:The present study ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200018100-00010
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:Various studies have suggested that a delay in the time between diagnosing hypertension and its correct control (D-C, diagnostic-control time) is linked to a worse prognosis. The aim of this study was to examine the relationship between D-C time and all-cause mortality, or the incidence of cardiovascular even...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000001896
更新日期:2019-02-01 00:00:00
abstract::Over the last few years, much progress has been made in understanding the genetic basis of primary aldosteronism. This has led to the diagnosis of the familial forms and has aided the understanding of the basis of sporadic forms of the disease. Such information can be exploited to improve the therapeutic approaches us...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/00004872-200404000-00001
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:C-reactive protein (CRP) both reflects and participates in inflammation, and its circulating concentration marks cardiovascular risk. Here we sought to understand the role of heredity in determining CRP secretion. METHODS:CRP, as well as multiple facets of the metabolic syndrome, were measured in a series o...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328011753e
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:We investigated to what extent anthropometric and lifestyle factors contributed to the classification of Chinese individuals into groups with white-coat, masked and sustained hypertension (HT). METHODS:We measured the office and ambulatory blood pressure (BP) in 694 Chinese enrolled in the JingNing populatio...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282efeee7
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Chronic diabetes is associated with alterations in autonomic modulation of the cardiovascular system. Although the rat has been used extensively in studies of experimental diabetes, there have been no reports on the changes in autonomic modulation of the cardiovascular function in chronic diabetic rats. OBJ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199917040-00006
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:To investigate methods to diagnose renal artery stenosis (RAS) among the general hypertensive population. METHODS:We studied the value of clinical and biochemical characteristics at the outpatient clinic to identify subjects with a renal artery narrowing of more than 50% of the luminal surface among 1047 hyp...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199007000-00003
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199715120-00070
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to identify the time of blood pressure (BP) drop in the orthostatic hypotension test, and to propose a realistic and appropriate duration in the orthostatic hypotension test. METHODS:A total of 879 consecutive patients (61-year-old and 44% women) with positive on the orthostatic...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002554
更新日期:2020-11-01 00:00:00
abstract::Systemic and regional haemodynamic effects of renal denervation were evaluated in adult (six-month-old) male spontaneously hypertensive rats (SHR) using the Fick procedure and electromagnetic flowmetry technique. Renal denervation (bilateral, 10% phenol in ethanol), performed five to eight days before the experiment, ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198312000-00010
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVES:High blood pressure is known to be associated with higher cardiovascular risk. The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality. METHODS:In th...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835a4dd8
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To estimate the sensitivity and specificity of self-reported hypertension (HTN) as compared with the clinical diagnosis in epidemiological studies. METHODS:We searched MEDLINE, Embase, Scopus, Web of Science, LILACS, Google Scholar, and ProQuest Dissertations & Theses Global: Health & Medicine databases. In ...
journal_title:Journal of hypertension
pub_type: 杂志文章,meta分析
doi:10.1097/HJH.0000000000001648
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Inflammatory processes may play a pivotal role in the pathogenesis of cerebrovascular injury in salt-loaded, stroke-prone, spontaneously hypertensive rats (SHRSP). Thromboxane A2 (TP) receptor stimulation by 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha) is involved in the process of vascular inflammation. O...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3280464dc8
更新日期:2007-04-01 00:00:00
abstract::Cardiovascular risk increases with chronological as well as biological aging, and one marker of this might be telomere length. The telomere cap is located at the end of the DNA helix and serves to protect its end. This is an evolutionary adaptation which has resulted in stabilization of the DNA strand within the chrom...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/HJH.0b013e328353e512
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Anandamide (AEA), one of the endocannabinoid compounds, has an important regulatory function by serving as an autocrine/paracrine or endocrine factor throughout the body via activation of the cannabinoid receptor 1 (CB1) and/or the transient receptor potential vanilloid type 1 (TRPV1) channels. However, the ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000249706.42230.a8
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:Functional sex differences are described in several vascular beds. In the case of renal vessels, sex differences could influence processes like regulation of blood pressure and ion balance. Angiotensin II and nitric oxide are important regulators of renal vascular tone. Females have higher nitric oxide syntha...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835731dd
更新日期:2012-09-01 00:00:00