Clinical and biochemical criteria in the detection of renal artery stenosis.

Abstract:

OBJECTIVE:To investigate methods to diagnose renal artery stenosis (RAS) among the general hypertensive population. METHODS:We studied the value of clinical and biochemical characteristics at the outpatient clinic to identify subjects with a renal artery narrowing of more than 50% of the luminal surface among 1047 hypertensive patients. Included in the analysis were: blood pressure, age, sex, body mass index, endogeneous creatinine clearance, smoking and plasma renin activity. RESULTS:Among the 1047 patients, 355 were selected for angiography. In this subgroup 104 patients (29%) had RAS. The subjects with RAS had significantly higher diastolic and systolic blood pressures than did those without stenosis. Forward stepwise logistical regression analysis showed that systolic blood pressure, stimulated plasma renin activity and smoking were the most predictive independent screening variables for the presence of RAS. Yet, none of these characteristics or their combinations were sufficiently sensitive to distinguish reliably between patients with essential hypertension and those with RAS. Sytolic blood pressure > 160 mmHg or diastolic blood pressure > 100 mmHg on automatic (Dinamap) recording as criteria selected a subgroup of patients with a RAS prevalence of 30%. CONCLUSIONS:By using blood pressure screening criteria a subgroup of hypertensive patients with a high prevalence of RAS can be formed in whom further invasive tests for RAS are indicated and efficient.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Bijlstra PJ,Postma CT,de Boo T,Thien T

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

1033-40

issue

8

eissn

0263-6352

issn

1473-5598

journal_volume

14

pub_type

杂志文章
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  • Effect of oral magnesium supplementation on blood pressure, platelet aggregation and calcium handling in deoxycorticosterone acetate induced hypertension in rats.

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    更新日期:2000-07-01 00:00:00

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    journal_title:Journal of hypertension

    pub_type: 杂志文章

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    更新日期:1993-01-01 00:00:00

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    journal_title:Journal of hypertension

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    authors: Chatterjee P,Kopriva SE,Chiasson VL,Young KJ,Tobin RP,Newell-Rogers K,Mitchell BM

    更新日期:2013-07-01 00:00:00

  • Omega-3 polyunsaturated fatty acid supplements and ambulatory blood pressure monitoring parameters in patients with mild essential hypertension.

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    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Russo C,Olivieri O,Girelli D,Azzini M,Stanzial AM,Guarini P,Friso S,De Franceschi L,Corrocher R

    更新日期:1995-12-01 00:00:00

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    更新日期:2009-03-01 00:00:00

  • Glomerular hemodynamics and arterial function in normal individuals.

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    authors: Fesler P,du Cailar G,Ribstein J,Mimran A

    更新日期:2010-12-01 00:00:00

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    更新日期:2012-05-01 00:00:00

  • Red blood cell Na content, Na, Li-countertransport, family history of hypertension and blood pressure in school children.

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    pub_type: 杂志文章

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    更新日期:1988-03-01 00:00:00

  • Renal angioplasty: better for treating hypertension or for rescuing renal function?

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    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-199917120-00001

    authors: Morganti A

    更新日期:1999-12-01 00:00:00

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    pub_type: 杂志文章,meta分析

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    更新日期:2007-03-01 00:00:00

  • Hypertension without cardiac hypertrophy does not induce a cardiac baroreflex deficit.

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    pub_type: 杂志文章

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    更新日期:1996-10-01 00:00:00

  • Beneficial interactions between pharmacological, pathophysiological and hypertension research.

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    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

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    更新日期:1999-12-01 00:00:00

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    journal_title:Journal of hypertension

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  • Hypertension aggregates in families of kidney stone patients with high urinary excretion of uric acid.

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  • Interstrain restriction fragment length polymorphism of c-fos and c-src oncogene loci in spontaneously hypertensive and normotensive rats.

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    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

    更新日期:1988-10-01 00:00:00

  • Arterial hypertension and cerebral hemodynamics: impact of head-down tilt on cerebral blood flow (arterial spin-labeling-MRI) in healthy and hypertensive patients.

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  • The effect of losartan on global and focal cerebral perfusion and on renal function in hypertensives in mild early ischaemic stroke.

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    pub_type: 临床试验,杂志文章,随机对照试验

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    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

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    更新日期:1988-02-01 00:00:00

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