Hypertension aggregates in families of kidney stone patients with high urinary excretion of uric acid.

abstract：OBJECTIVE:To investigate the role of an activated endothelin system in the renal dysfunction observed in chronic heart failure after myocardial infarction. METHODS:In rats with heart failure after myocardial infarction and in sham-operated animals (Sham), we investigated the effect on renal function of long-term oral ...

journal_title：Journal of hypertension

authors： Bauersachs J,Braun C,Fraccarollo D,Widder J,Ertl G,Schilling L,Kirchengast M,Rohmeiss P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:The main objective was to examine the role of hemodynamics in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation (SAD). DESIGN AND METHODS:Rats were examined at different times after SAD or sham operation (Sham). Hemodynamics were recorded continuously in conscious unrestrained ra...

journal_title：Journal of hypertension

authors： Miao CY,Su DF

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:In the BEtter control of BP in hypertensive pAtients monitored Using the HOTMAN sYstem study, we investigated whether utilizing noninvasive monitoring of hemodynamic parameters combined with a drug selection algorithm (integrated hemodynamic management - IHM) compared with conventional drug selection may imp...

journal_title：Journal of hypertension

authors： Fadl Elmula FE,Rebora P,Talvik A,Salerno S,Miszkowska-Nagórna E,Liu X,Heinpalu-Kuum M,Comotti T,Larstorp AC,Rostrup M,Świerblewska E,Valsecchi MG,Kjeldsen SE,Viigimaa M,Narkiewicz K,Parati G,Laurent S,BEtter control of

更新日期：2015-12-01 00:00:00

abstract：:Ca2+ pump kinetics were investigated in erythrocytes from 22 essential hypertensive patients and 20 normotensive controls (under initial-rate and steady-state conditions, using Sr2+ as a Ca2+ analogue). The mean value of the apparent dissociation constant for total internal Ca2+ (KCa) was slightly but significantly in...

journal_title：Journal of hypertension

authors： de la Sierra A,Hannaert P,Ollivier JP,Senn N,Garay R

更新日期：1990-03-01 00:00:00

abstract：:Nitric oxide formed by neuronal nitric oxide synthase (nNOS) in the brain, autonomic inhibitory (nitrergic) nerves, and heart plays important roles in the control of blood pressure. Activation of nitrergic nerves innervating the systemic vasculature elicits vasodilatation, decreases peripheral resistance, and lowers b...

journal_title：Journal of hypertension

authors： Toda N,Ayajiki K,Okamura T

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Based on results of in vitro studies, it has been hypothesized that blockade of the renin-angiotensin system (RAS) promotes the recruitment and differentiation of pre-adipocytes and that increased formation of small insulin-sensitive adipocytes counteracts ectopic deposition of lipids, thereby improving insul...

journal_title：Journal of hypertension

authors： Furuhashi M,Ura N,Takizawa H,Yoshida D,Moniwa N,Murakami H,Higashiura K,Shimamoto K

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Hypertension in midlife adults is associated with cognitive decline later in life. In individuals treated for hypertension, blood pressure (BP) loads have been associated with end organ damages. This study examines whether BP load inversely correlates with performance in cognitive tasks in normotensive or ...

journal_title：Journal of hypertension

authors： Noriega de la Colina A,Wu R,Desjardins-Crépeau L,Badji A,Lamarre-Cliche M,Doyon J,Bherer L,Girouard H

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To estimate the compliance rate and associated factors among a population of hypertensive subjects registered in hospitals and primary health care centres. DESIGN:A prospective study carried out on a sample of hypertensive subjects. METHOD:Compliance with treatment by the study sample was measured using the...

journal_title：Journal of hypertension

authors： Khalil SA,Elzubier AG

更新日期：1997-05-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinica...

journal_title：Journal of hypertension

authors： Grassi G,Seravalle G,Maloberti A,Facchetti R,Cuspidi C,Bombelli M,Laurent S,Redon J,Mancia G

更新日期：2015-11-01 00:00:00

abstract：:Thirty-two patients with mildly elevated blood pressure (BP), but without target organ damage, attended a BP measuring clinic where duplicate BP measurements were made on 12 visits. During visits 1-3, BP showed a systematic decrease which varied from patient to patient. During visits 4-12, no further systematic change...

journal_title：Journal of hypertension

authors： Watson RD,Lumb R,Young MA,Stallard TJ,Davies P,Littler WA

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVES:To study the relation between the blood pressure and the neurocognitive function within the full adult age range in a large population sample. DESIGN:A cross-sectional study of 936 healthy adults who were recruited from a register of family practices, stratified for age (24-81 years), sex, and occupational ...

journal_title：Journal of hypertension

authors： van Boxtel MP,Gaillard C,Houx PJ,Buntinx F,de Leeuw PW,Jolles J

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:Studies directly comparing the associations of intima-media thickness with blood pressure (BP) on manual sphygmomanometric blood pressure measurement (SBPM) and 24-h ambulatory blood pressure measurement (ABPM) are scarce and have a cross-sectional design. METHODS:At baseline, we measured systolic and diasto...

journal_title：Journal of hypertension

authors： Dechering DG,Wizner B,Adiyaman A,Nawrot T,Jin Y,Richart T,Kuznetsova T,Struijker-Boudier HA,Thien T,Staessen JA

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Urinary excretion of angiotensinogen [urine angiotensinogen (UAGT)] has been proposed as a biomarker of intrarenal renin-angiotensin system activity. We investigated the association between UAGT and salt-sensitivity and potassium-sensitivity of blood pressure (BP) among Genetic Epidemiology Network of Salt Se...

journal_title：Journal of hypertension

authors： Rebholz CM,Chen J,Zhao Q,Chen JC,Li J,Cao J,Gabriel Navar L,Lee Hamm L,Gu D,He J,GenSalt Collaborative Research Group.

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To conduct a longitudinal evaluation of the central haemodynamic adaptations of normal pregnancy. METHODS:This was a prospective longitudinal study involving healthy, normotensive women who were having an uncomplicated, singleton pregnancy. Brachial and central SBP, DBP, mean arterial pressure (MAP), brachia...

journal_title：Journal of hypertension

authors： O' Callaghan KM,Hennessy Á,Malvisi L,Kiely M

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:To assess the predictive role of changes in albuminuria on the loss of renal function under antihypertensive treatment in patients with type 2 diabetes (T2D). METHODS:Clinical records from a total of 12 611 patients with hypertension and T2D, attending 100 antidiabetic centers in Italy, with normal estimate...

journal_title：Journal of hypertension

authors： Viazzi F,Ceriello A,Fioretto P,Giorda C,Guida P,Russo G,Greco E,De Cosmo S,Pontremoli R,AMD-Annals Study Group.

更新日期：2018-08-01 00:00:00

abstract：AIM:To examine the effect of renal denervation (RDN) on blood pressure (BP) and health-related quality of life (QoL) in patients with resistant hypertension, pseudoresistant hypertension due to a white-coat effect and in patients with uncontrolled masked hypertension. METHODS:Using the Medical Outcomes Study 36-Item S...

journal_title：Journal of hypertension

authors： Lambert GW,Hering D,Marusic P,Thorp A,Sata Y,Lee R,Duval J,Hammond L,Head GA,Esler MD,Lambert EA,Dixon JB,Dhar AK,Barton DA,Schlaich MP

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinic and ambulatory blood pressure (BP)-lowering efficacy and safety of an aliskiren/amlodipine/hydrochlorothiazide (HCT) triple combination compared with the component dual combinations, in patients with moderate-to-severe hypertension. METHODS:This 8-week, double-blind, randomized, activ...

journal_title：Journal of hypertension

authors： Lacourcière Y,Taddei S,Konis G,Fang H,Severin T,Zhang J

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To examine the association of blood pressure (BP) with cardiovascular mortality in real-world settings and investigate whether that association varied by use of antihypertensive medication at baseline. METHODS:Data from 27 728 Japanese men and women, aged 40-79 years, free of stroke, coronary heart disease, ...

journal_title：Journal of hypertension

authors： Yamagishi K,Sawachi S,Tamakoshi A,Iso H,JACC Study Group.

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To examine the regulation by angiotensin II and by steroids of the expression of the angiotensin II AT1a and AT1b receptor genes in rat hearts. METHODS:Endogenous levels of angiotensin II in the rats were increased either by unilateral 0.2-mm renal artery clips or by subcutaneous infusions of frusemide (12 m...

journal_title：Journal of hypertension

authors： Della Bruna R,Ries S,Himmelstoss C,Kurtz A

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Epidemiological investigations have demonstrated a close association between heavy alcohol consumption and hypertension. The mechanisms of this association, however, remain elusive. We studied the effects of alcohol withdrawal on blood pressure, hormonal parameters, and circulating markers of endothelial act...

journal_title：Journal of hypertension

authors： Soardo G,Donnini D,Varutti R,Milocco C,Basan L,Esposito W,Casaccio D,Isola M,Soldano F,Sechi LA

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) may lead to the development of hypertension and therapy with continuous positive airway pressure (CPAP) can promote reduction in blood pressure. OBJECTIVE:The objective of this study is to review systematically the effects of CPAP on blood pressure in patients with OSA. METHOD...

journal_title：Journal of hypertension

authors： Schein AS,Kerkhoff AC,Coronel CC,Plentz RD,Sbruzzi G

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Evidence about sex differences in blood pressure (BP) at the time of acute stroke presentation is scarce. We aimed to summarize available data on sex differences in BP at the time of acute stroke presentation, including stratification by prior history of hypertension and stroke subtype. METHODS:We performed...

journal_title：Journal of hypertension

authors： Li J,Yang SC,Moullaali TJ,Chen R,Woodward M,Carcel C,Delcourt C,Sandset EC,Anderson C,Chen G,Wang X

更新日期：2019-10-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH), despite its adaptive nature, increases cardiovascular morbidity and mortality. Novel approaches for protection against pathological heart remodelling are presented in this supplement. Melatonin diminishes myocardial fibrosis in rats exposed to continuous light and N-nitro-L-arginine...

journal_title：Journal of hypertension

authors： Simko F,Pechanova O

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To introduce a new method, the smoothness index, for assessing the homogeneity of 24 h blood pressure reduction by antihypertensive treatment and to compare it with the trough : peak ratio; and to assess the ability of both indices to predict a reduction in the left ventricular mass index induced by treatment...

journal_title：Journal of hypertension

authors： Parati G,Omboni S,Rizzoni D,Agabiti-Rosei E,Mancia G

更新日期：1998-11-01 00:00:00

abstract：:Experimental models of genetic hypertension are used to develop paradigms to study human essential hypertension while removing some of the complexity inherent in the study of human subjects. Since 1991 several quantitative trait loci responsible for blood pressure regulation have been identified in various rat crosses...

journal_title：Journal of hypertension

authors： Dominiczak AF,Clark JS,Jeffs B,Anderson NH,Negrin CD,Lee WK,Brosnan MJ

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:To investigate the mechanism of angiotensin II-induced apoptosis in cultured cardiomyocytes by determining which receptor subtype is involved, and what is the relationship between intracellular Ca2+ changes and apoptosis. DESIGN AND METHODS:Neonatal rat cardiomyocytes were pretreated with either the AT1 ant...

journal_title：Journal of hypertension

authors： Goldenberg I,Grossman E,Jacobson KA,Shneyvays V,Shainberg A

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of angiotensinogen (AGT) gene with AGT level and hypertension based on the overall genetic variation of the AGT gene in among African-Americans. METHODS:All non-rare single nucleotide polymorphisms (SNPs) in AGT were identified by resequencing 24 individuals. Five tagging SNPs wer...

journal_title：Journal of hypertension

authors： Wu X,Luke A,Rieder M,Lee K,Toth EJ,Nickerson D,Zhu X,Kan D,Cooper RS

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Aldosterone is produced in the ventricle of patients with hypertension. The present study was designed to examine whether adrenocorticotropic hormone (ACTH) and cortisol are also produced from the heart in patients with essential hypertension. METHODS:The study population consisted of 57 patients with essent...

journal_title：Journal of hypertension

authors： Mizuno Y,Yasue H,Yoshimura M,Harada E,Fujii H,Nakamura S,Yamamoto N,Ogawa H,Nakao K

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate whether adjustment for frailty influences the relationship of blood pressure with mortality in elderly patients with type 2 diabetes mellitus (T2DM). METHODS:Patients aged 60 years and older (n = 858) were selected from a prospective observational cohort study of primary care patients...

journal_title：Journal of hypertension

authors： van Hateren KJ,Hendriks SH,Groenier KH,Bakker SJ,Bilo HJ,Kleefstra N,Landman GW

更新日期：2015-06-01 00:00:00

abstract：:Ischemic renal disease (IRD) is defined as a clinically important reduction in glomerular filtration rate or loss of renal parenchyma caused by hemodynamically significant renal artery stenosis. IRD is a common and often overlooked clinical entity that presents itself in the setting of extrarenal arteriosclerotic vasc...

journal_title：Journal of hypertension

authors： Preston RA,Epstein M

更新日期：1997-12-01 00:00:00