Drug compliance among hypertensive patients in Tabuk, Saudi Arabia.

Abstract:

OBJECTIVE:To estimate the compliance rate and associated factors among a population of hypertensive subjects registered in hospitals and primary health care centres. DESIGN:A prospective study carried out on a sample of hypertensive subjects. METHOD:Compliance with treatment by the study sample was measured using the pill-counting method. The reasons for noncompliance are listed and the status of blood pressure control among compliant and noncompliant subjects is reported. RESULTS:The compliance rate was 53.0%. It was associated positively with male sex, and negatively with older age, symptoms of illness and drug side effects. The degree of blood pressure control was worse among noncompliant subjects. Reasons for noncompliance included the asymptomatic nature of hypertension, a shortage of drugs, side effects, forgetfulness and lack of health education. CONCLUSIONS:The compliance rate was low in this study and was accompanied by inadequate blood pressure control among noncompliant subjects. Disoriented behavior regarding hypertension and its medications was observed.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Khalil SA,Elzubier AG

doi

10.1097/00004872-199715050-00013

subject

Has Abstract

pub_date

1997-05-01 00:00:00

pages

561-5

issue

5

eissn

0263-6352

issn

1473-5598

journal_volume

15

pub_type

杂志文章
  • The effect of losartan on global and focal cerebral perfusion and on renal function in hypertensives in mild early ischaemic stroke.

    abstract:BACKGROUND:Secondary prevention of stroke with antihypertensive drugs is now standard practice, but it is unclear how soon after a cerebrovascular event antihypertensive therapy should be initiated or re-started. Due to impaired cerebral autoregulation, changes in systemic blood pressure may be reflected in cerebral pe...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200405000-00022

    authors: Nazir FS,Overell JR,Bolster A,Hilditch TE,Reid JL,Lees KR

    更新日期:2004-05-01 00:00:00

  • Long-term effects of antihypertensive therapy on cardiovascular events and new-onset diabetes mellitus in high-risk hypertensive patients in Japan.

    abstract:OBJECTIVE:During the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial, patients with hypertension who received amlodipine had similar cardiovascular risks as those who received candesartan. We conducted a post-trial study, the Candesartan Antihypertensive Survival Evaluation in Japan 10-year fol...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001780

    authors: Liu J,Yasuno S,Oba K,Konda M,Ichihara C,Kitao H,Kuwabara Y,Ueshima K

    更新日期:2018-09-01 00:00:00

  • Prestroke treatment with beta-blockers for hypertension is not associated with severity and poor outcome in patients with ischemic stroke: data from a national stroke registry.

    abstract:BACKGROUND:Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypert...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001218

    authors: Koton S,Tanne D,Grossman E

    更新日期:2017-04-01 00:00:00

  • Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study.

    abstract:BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32830fe4a5

    authors: Lago RM,Pencina MJ,Wang TJ,Lanier KJ,D'Agostino RB,Kannel WB,Vasan RS

    更新日期:2008-11-01 00:00:00

  • The effects of insulin and insulin-like materials in the brain on central cardiovascular regulation: with special reference to the central effects of sodium chloride.

    abstract::The present study investigated the roles of insulin on central cardiovascular regulation. When rats were fed with a high-salt diet for 4 weeks, hypothalamic and pituitary contents of insulin-like immunoreactive substance (ILI) significantly decreased. The plasma concentration of ILI remained unaltered, however. Intrac...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199106000-00006

    authors: Nishimura M,Takahashi H,Matsusawa M,Ikegaki I,Nakanishi T,Yoshimura M

    更新日期:1991-06-01 00:00:00

  • Effect on blood pressure of lumiracoxib versus ibuprofen in patients with osteoarthritis and controlled hypertension: a randomized trial.

    abstract:OBJECTIVES:Nonsteroidal anti-inflammatory drugs vary in their impact on blood pressure and the effect of lumiracoxib 100 mg once daily has not been studied previously. To examine whether lumiracoxib 100 mg once daily would result in lower 24-h mean systolic ambulatory blood pressure than ibuprofen 600 mg three times da...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/HJH.0b013e328302c9fe

    authors: MacDonald TM,Reginster JY,Littlejohn TW,Richard D,Lheritier K,Krammer G,Rebuli R

    更新日期:2008-08-01 00:00:00

  • Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.

    abstract:OBJECTIVE:In previous studies we demonstrated that the administration of furosemide associated with L-arginine contributes to enhanced hypotension and induces greater water than electrolyte excretion, in both normal and expansion conditions. The aim of the present study was to elucidate the interaction between furosemi...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000125445.28861.8a

    authors: Costa MA,Loria A,Elesgaray R,Balaszczuk AM,Arranz C

    更新日期:2004-08-01 00:00:00

  • Excessive zinc intake elevates systemic blood pressure levels in normotensive rats--potential role of superoxide-induced oxidative stress.

    abstract:OBJECTIVES:The present study was designed to examine whether or not excessive Zn intake affects systemic blood pressure (BP) levels in a normotensive state. METHODS:Systolic BP (SBP) and mean arterial pressure (MAP) before and after administration of the nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200403000-00017

    authors: Yanagisawa H,Sato M,Nodera M,Wada O

    更新日期:2004-03-01 00:00:00

  • Can we trust automatic sphygmomanometer validations?

    abstract::Hypertension is a leading risk factor for mortality. Detecting, treating and monitoring hypertensive patients require accurate blood pressure measurements. Protocols for validation of automatic sphygmomanometers exist, but quality control of validations is limited to peer review of published reports, which has severe ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/HJH.0b013e32833e1011

    authors: Turner MJ

    更新日期:2010-12-01 00:00:00

  • Analysis of circadian blood pressure rhythm and target-organ damage in stroke-prone spontaneously hypertensive rats.

    abstract:OBJECTIVE:We compared diurnal patterns of blood pressure in Wistar-Kyoto (WKY) rats, spontaneously hypertensive rats (SHR) and stroke-prone spontaneously hypertensive rats (SHRSP), and analyzed the relationship between the change in diurnal patterns of blood pressure and target-organ damage in SHRSP. MATERIALS AND MET...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917020-00005

    authors: Shimamura T,Nakajima M,Iwasaki T,Hayasaki Y,Yonetani Y,Iwaki K

    更新日期:1999-02-01 00:00:00

  • Eplerenone enhances cardioprotective effects of standard heart failure therapy through matricellular proteins in hypertensive heart failure.

    abstract:AIMS:The addition of an aldosterone receptor antagonist on top of current optimal therapy (based on angiotensin II inhibition) has demonstrated an important clinical benefit in heart failure patients with systolic dysfunction. Whether this finding also applies to heart failure patients with preserved systolic function ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328364abd6

    authors: Muñoz-Pacheco P,Ortega-Hernández A,Caro-Vadillo A,Casanueva-Eliceiry S,Aragoncillo P,Egido J,Fernández-Cruz A,Gómez-Garre D

    更新日期:2013-11-01 00:00:00

  • Impact of genes related to immune tolerance and inflammation (tumour necrosis factor-alpha, interleukin-6) on blood pressure, protein excretion and oedema in pregnancy.

    abstract:OBJECTIVE:To test the hypothesis that genetically determined alterations of maternal immune tolerance to a foetal semi-allograft are important for the pathogenesis of hypertensive disorders in pregnancy. DESIGN:A genetic association study was performed to analyse the impact of genetic polymorphisms known to be involve...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000188732.52722.5a

    authors: Pfab T,Chen YP,Slowinski T,Richter CM,Godes M,Arck PC,Halle H,Hocher B

    更新日期:2005-12-01 00:00:00

  • The effect of alternative criteria for hypertension on estimates of prevalence and control.

    abstract:OBJECTIVES:To assess the impact of various criteria used to define hypertension in community surveys on estimates of prevalence, treatment and control. In particular, this paper examines the effect of using mean versus minimum values; one, two or three examinations; and three different blood pressure levels. DESIGN:A ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715030-00004

    authors: Birkett NJ

    更新日期:1997-03-01 00:00:00

  • The impact of age on vascular smooth muscle function in humans.

    abstract:AIM:Advanced age is associated with vascular endothelial dysfunction, characterized by reductions in the endothelium-dependent vasodilation of the conduit and resistance arteries, in part, from decreased nitric oxide bioavailability. Although vascular smooth muscle function (SMF), assessed by responsiveness to an exoge...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/HJH.0000000000000446

    authors: Montero D,Pierce GL,Stehouwer CD,Padilla J,Thijssen DH

    更新日期:2015-03-01 00:00:00

  • Is atrial natriuretic peptide-guanosine 3',5' cyclic monophosphate coupling a determinant of urinary sodium excretion in essential hypertension?

    abstract:OBJECTIVES:(1) To compare urinary guanosine 3',5' cyclic monophosphate (cyclic GMP) excretion between normotensive subjects and essential hypertensive patients; (2) to determine the influence of changes in sodium intake on urinary cyclic GMP excretion in response to the neutral endopeptidase inhibitor candoxatril in es...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-199204000-00005

    authors: Sagnella GA,Singer DR,Markandu ND,Buckley MG,MacGregor GA

    更新日期:1992-04-01 00:00:00

  • Female sexual dysfunction in essential hypertension: a common problem being uncovered.

    abstract:OBJECTIVES:Female sexual dysfunction (FSD) is increasingly attracting more scientific and public interest, and represents a poorly investigated issue in patients with essential hypertension. We evaluated the prevalence of sexual dysfunction in hypertensive women compared with normotensive women according to age, hypert...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000251898.40002.5b

    authors: Doumas M,Tsiodras S,Tsakiris A,Douma S,Chounta A,Papadopoulos A,Kanellakopoulou K,Giamarellou H

    更新日期:2006-12-01 00:00:00

  • Impact of transiently elevated diastolic pressure on cause of death: 29-year follow-up from the General Practice Hypertension Study Group.

    abstract:OBJECTIVES:High blood pressure is known to be associated with higher cardiovascular risk. The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality. METHODS:In th...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32835a4dd8

    authors: Peters R,Wells F,Bulpitt C,Beckett N

    更新日期:2013-01-01 00:00:00

  • Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project.

    abstract:OBJECTIVE:To study the association between polymorphisms in the angiotensin converting enzyme (ACE) gene and angiotensinogen (AGT) gene and hypertension and/or type 2 diabetes in a community population. PATIENTS AND METHODS:The insertion (I)/deletion (D) polymorphism of the ACE gene and the M235T polymorphism of the A...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917110-00010

    authors: Bengtsson K,Orho-Melander M,Lindblad U,Melander O,Bøg-Hansen E,Ranstam J,Råstam L,Groop L

    更新日期:1999-11-01 00:00:00

  • The influence of low job control on ambulatory blood pressure and perceived stress over the working day in men and women from the Whitehall II cohort.

    abstract:OBJECTIVE:Work stress contributes to risk of coronary heart disease and hypertension. This study tested the influence of job control on ambulatory blood pressure, and ratings of perceived stress and happiness in men and women systematically sampled by socio-economic status from the Whitehall II epidemiological cohort. ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200405000-00012

    authors: Steptoe A,Willemsen G

    更新日期:2004-05-01 00:00:00

  • Congenital defects and early childhood outcomes following in-utero exposure to antihypertensive medication.

    abstract:BACKGROUND:Hypertensive disorders during pregnancy are an important risk to mother and fetus, frequently necessitating antihypertensive treatment. Data describing the safety of in-utero exposure to antihypertensive treatment is conflicting with many studies suffering from significant methodological issues. METHOD:We c...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002670

    authors: Fitton CA,Fleming M,Aucott L,Pell JP,Mackay DF,McLay JS

    更新日期:2020-10-09 00:00:00

  • Low sodium diet inhibits the local counter-regulator effect of angiotensin-(1-7) on angiotensin II.

    abstract:OBJECTIVE:The heptapeptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a versatile, endogenous inhibitor of the renin-angiotensin system (RAS). As the therapeutic response to exogenous RAS inhibitors, such as AT1 receptor antagonists, is altered by changes in salt intake, we investigated the effect of a low, n...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200412000-00018

    authors: Roks AJ,Nijholt J,van Buiten A,van Gilst WH,de Zeeuw D,Henning RH

    更新日期:2004-12-01 00:00:00

  • Severe obstructive sleep apnea elicits concentric left ventricular geometry.

    abstract:BACKGROUND:Obstructive sleep apnea (OSA) has several negative effects on the heart including increase in myocardial end-systolic stress, venous return and sympathetic activity, all potential stimuli of left ventricular (LV) hypertrophy. The impact of the severity of OSA on LV geometry is unknown. We hypothesized that O...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/hjh.0b013e328336c90a

    authors: Cioffi G,Russo TE,Stefenelli C,Selmi A,Furlanello F,Cramariuc D,Gerdts E,de Simone G

    更新日期:2010-05-01 00:00:00

  • Influence of left ventricular mass, uremia and hypertension on vagal tachycardic reserve.

    abstract:BACKGROUND:Left ventricular (LV) hypertrophy, arterial hypertension and end-stage renal disease (ESRD) are associated with deranged cardiac parasympathetic regulation and increased cardiovascular risk. These conditions often co-exist but little is known about the relative contribution of LV mass, arterial blood pressur...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200308000-00020

    authors: Mircoli L,Rivera R,Bonforte G,Fedele L,Genovesi S,Surian M,Ferrari AU

    更新日期:2003-08-01 00:00:00

  • Time point of blood pressure drop in patients with orthostatic hypotension in the emergency department.

    abstract:OBJECTIVE:The purpose of this study was to identify the time of blood pressure (BP) drop in the orthostatic hypotension test, and to propose a realistic and appropriate duration in the orthostatic hypotension test. METHODS:A total of 879 consecutive patients (61-year-old and 44% women) with positive on the orthostatic...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002554

    authors: Jang K,Park M,Kim HL

    更新日期:2020-11-01 00:00:00

  • Reduction of blood pressure variability by combination therapy in spontaneously hypertensive rats.

    abstract:OBJECTIVE:To test the hypothesis that combination therapy might be a powerful tool to reduce blood pressure variability (BPV) in the treatment of hypertension. METHODS:In chronic studies, male spontaneously hypertensive rats were given drugs in their rat chow for 18 weeks (n = 9 or 10 for each group of rats). Doses we...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3282ef547f

    authors: Xie HH,Shen FM,Xu LP,Han P,Miao CY,Su DF

    更新日期:2007-11-01 00:00:00

  • Is it time to measure microalbuminuria in hypertension?

    abstract::Former guidelines on hypertension never made a commitment to the detection of microalbuminuria for screening or follow-up of hypertensive patients. On the other hand, growing evidence support the contributory role of microalbuminuria in the prediction of absolute cardiovascular risk in hypertension and document the po...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-200307000-00001

    authors: Volpe M,Cosentino F,Ruilope LM

    更新日期:2003-07-01 00:00:00

  • Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.

    abstract:OBJECTIVES:We hypothesized that the aldosterone: renin ratio (ARR) predicts the antihypertensive response to mineralocorticoid receptor antagonist, spironolactone (SPIRO), when compared with bendroflumethiazide (BFZ). METHODS:We conducted a randomized, crossover, trial on hypertensive patients with either high ARR (HA...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/HJH.0b013e328332b79b

    authors: Parthasarathy HK,Alhashmi K,McMahon AD,Struthers AD,McInnes GT,Ford I,Connell JM,MacDonald TM

    更新日期:2010-01-01 00:00:00

  • Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension.

    abstract:OBJECTIVES:The antihypertensive effect of thiazide diuretics in angiotensin II induced hypertension has never been characterized. In the current study, we sought to determine the effect of a thiazide diuretic on arterial pressure and renal fluid excretion in rats receiving a chronic intravenous infusion of angiotensin ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200109000-00012

    authors: Ballew JR,Fink GD

    更新日期:2001-09-01 00:00:00

  • Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications.

    abstract::: Hypertension is a growing health concern worldwide. Established hypertension is a causative factor of heart failure, which is characterized by increased vascular resistance and intractable uncontrolled blood pressure. Hypertension and heart failure have multiple causes and complex pathophysiology but cellular immuni...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002456

    authors: Rai A,Narisawa M,Li P,Piao L,Li Y,Yang G,Cheng XW

    更新日期:2020-10-01 00:00:00

  • Hypertension awareness, treatment and control among ethnic minority populations in Europe: a systematic review and meta-analysis.

    abstract:OBJECTIVE:Ethnic minority populations (EMPs) are disproportionally affected by hypertension-mediated complications compared with European host populations (EHPs), which might be due to disparities in hypertension awareness, treatment and control. We conducted a systematic review and meta-analysis to compare awareness, ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002651

    authors: van der Linden EL,Couwenhoven BN,Beune EJAJ,Daams JG,van den Born BH,Agyemang C

    更新日期:2021-02-01 00:00:00