Reduction of blood pressure variability by combination therapy in spontaneously hypertensive rats.

abstract：OBJECTIVES:To determine prevalence, awareness, treatment, and control of hypertension, and its risk factors in an urban Korean population. DESIGN AND SETTING:A cross-sectional survey in Ansan-city, Korea. SUBJECTS AND METHODS:Population-based samples of people aged 18-92 years in Ansan-city, Korea, were selected, yie...

journal_title：Journal of hypertension

authors： Jo I,Ahn Y,Lee J,Shin KR,Lee HK,Shin C

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Some cases of pseudopheochromocytoma have been described among hypertensive patients with obstructive sleep apnea (OSA). This study examined whether a pathological rise of urinary metanephrines is a common feature in hypertensive OSA patients and, in such a case, whether the ventilation treatment during sleep...

journal_title：Journal of hypertension

authors： Gilardini L,Lombardi C,Redaelli G,Mattaliano P,Fanari P,Cornacchia M,Scacchi M,Mai S,Ferronato P,Parati G,Invitti C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Inflammation is necessary for successful pregnancy; however, excessive inflammation plays a central role in the development of the pregnancy-specific hypertensive disorder preeclampsia. Numerous anti-inflammatory cytokines are decreased in women with preeclampsia but the role of individual cytokines in blood ...

journal_title：Journal of hypertension

authors： Chatterjee P,Kopriva SE,Chiasson VL,Young KJ,Tobin RP,Newell-Rogers K,Mitchell BM

更新日期：2013-07-01 00:00:00

abstract：:Interstrain restriction fragment length polymorphism was detected after Southern blot hybridization of spontaneously hypertensive (SHR) and control (WKY) rat DNA digested by Bam HI restrictase with a v-fos probe. The SHR genome was characterized by an additional minor band of 4.0 kb. Other restriction fragment length ...

journal_title：Journal of hypertension

authors： Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Genome-wide scans from Italy and China suggest a hypertension-susceptible locus between D2S2278 (nucleotides 11,245,080 - 11,245,358) and D2S168 (nucleotides 11,467,214 - 11,467,422) on chromosome 2. METHODS:We performed a large association study of polymorphisms in this region with blood pressure modulatio...

journal_title：Journal of hypertension

authors： Kamide K,Kokubo Y,Yang J,Tanaka C,Hanada H,Takiuchi S,Inamoto N,Banno M,Kawano Y,Okayama A,Tomoike H,Miyata T

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To follow the changes in blood pressure and echocardiographically determined left ventricular mass in offspring of mothers who had hypertension during pregnancy. DESIGN:Longitudinal study with a 5-year follow-up. METHODS:Nineteen offspring of mothers who had hypertension during pregnancy, and sustained hype...

journal_title：Journal of hypertension

authors： Himmelmann A,Svensson A,Hansson L

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To determine whether obese hypertensive patients manifest a diminished regional vasodilator response to an oral glucose challenge. METHODS:Nineteen obese hypertensives (body mass index 34.1 +/- 1.3 kg/m2, blood pressure 144 +/- 3/96 +/- 2 mmHg) and 13 lean controls (23.6 +/- 0.3 kg/m2, 127 +/- 4/83 +/- 3 mmH...

journal_title：Journal of hypertension

authors： Egan BM,Stepniakowski K

更新日期：1994-09-01 00:00:00

abstract：:This study determined the influence of baroreflex sensitivity (BRS) on the rate of urinary sodium excretion and plasma renin activity (PRA) in response to a saline infusion in conscious male rabbits specifically bred for high (Group I; n = 7) and low (Group II; n = 10) BRS and in seven control animals. Only Group II s...

journal_title：Journal of hypertension

authors： Weinstock M,Borosh M,Kafri O,Kaczmarczyk G

更新日期：1991-09-01 00:00:00

abstract：:The mechanisms involved in the diuretic action of the recently discovered group of atrial natriuretic peptides (ANP) are not entirely clear. To determine whether the diuresis and the changes in blood pressure produced by alpha-human ANP (alpha-hANP) involved a concomitant modification of circulating arginine-vasopress...

journal_title：Journal of hypertension

authors： Gnädinger MP,Weidmann P,Rascher W,Lang RE,Hellmüller B,Uehlinger DE

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:Current evidence demonstrates that both genetic and environmental factors influence blood pressure. The sympathetic nervous system is a key player in blood pressure control and functional genetic variants of the beta-2 adrenergic receptor (B2AR) have been identified and implicated in the pathogenesis of hype...

journal_title：Journal of hypertension

authors： Binder A,Garcia E,Wallace C,Gbenga K,Ben-Shlomo Y,Yarnell J,Brown P,Caulfield M,Skrabal F,Kotanko P,Munroe P

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Genome-wide association studies have linked variants of fat mass and obesity-associated protein (FTO) to obesity. However, the molecular function of FTO remains unclear. In this study, we sought to investigate the potential effects of FTO in modulating cholesterol deposition in macrophage foam cells, as well ...

journal_title：Journal of hypertension

authors： Mo C,Yang M,Han X,Li J,Gao G,Tai H,Huang N,Xiao H

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:We studied the vasoconstrictor effects of the thromboxane A2 (TxA2) analogue U46619 in the perfused hind limb of rats under constant flow before and after intravenous injection of irbesartan, an angiotensin II AT1 receptor antagonist, to test whether irbesartan interacts in vivo with the thromboxane A2/prosta...

journal_title：Journal of hypertension

authors： Fukuhara M,Neves LA,Li P,Diz DI,Ferrario CM,Brosnihan KB

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:The pregnant spontaneously hypertensive rat (SHR) exhibits a decrease in arterial blood pressure shortly before delivery; however, the mechanisms are unknown. Nitric oxide may be involved. DESIGN:Blood pressure in stroke-prone SHR (SHRSP) and Wistar-Kyoto control rats (WKY) was telemetrically measured. Four ...

journal_title：Journal of hypertension

authors： Gompf H,Luft FC,Morano I

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND METHOD:This study evaluated the effects of a linear block strength training programme on the parameters of cardiac remodelling in spontaneously hypertensive rats. Thirty-nine rats were equally distributed in four groups: normotensive sedentary, normotensive trained, hypertensive sedentary and hypertensiv...

journal_title：Journal of hypertension

authors： Perilhão MS,Krause Neto W,da Silva AA,Alves LLS,Antonio EL,Medeiros A,Rica RL,Serra AJ,Tucci PJF,Bocalini DS

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:We recently demonstrated that glucocorticoid increases the number of angiotensin II type 1 (AT1) receptors and their gene expression in cultured vascular smooth muscle cells. To clarify whether this mechanism participates in glucocorticoid-induced hypertension, we investigated the effect of dexamethasone on ...

journal_title：Journal of hypertension

authors： Sato A,Suzuki H,Nakazato Y,Shibata H,Inagami T,Saruta T

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Cross-sectional evidence indicates that eating frequency correlates with blood pressure, hypertension, and related target organ damage. The aim of the present study was to prospectively assess eating frequency as a predictor of arteriosclerosis progression and new onset hypertension over a follow-up period o...

journal_title：Journal of hypertension

authors： Karatzi K,Georgiopoulos G,Yannakoulia M,Efthimiou E,Voidonikola P,Mitrakou A,Manios E,Alevizaki M,Papamichael C,Stamatelopoulos K

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:We examined whether the early initiation of sexual activity is associated with hypertension in US adults, and whether the timing of first menstruation is meaningful in regard of this association. We also assessed the effect modification by ethnicity. METHODS:Using data from 2001 to 2016 National Health and ...

journal_title：Journal of hypertension

authors： Ngueta G,Ndjaboue R

更新日期：2018-12-01 00:00:00

abstract：:Plasma viscosity and fibrinogen concentrations were measured in 70 diabetics (35 hypertensive and 35 normotensive) and compared with those of 35 age- and sex-matched normotensive healthy subjects in relation to body weight. The body weight, body mass index, blood pressure (systolic and diastolic), mean arterial pressu...

journal_title：Journal of hypertension

authors： Memeh CU

更新日期：1990-08-01 00:00:00

abstract：:Although the blood vessels are exposed to high pressures in hypertension, the main complications of hypertension (stroke and myocardial infarction) are paradoxically thrombotic rather than haemorrhagic. In keeping with Virchow's triad, patients with hypertension do demonstrate abnormalities of vessel wall (endothelial...

journal_title：Journal of hypertension

authors： Lip GY,Li-Saw-Hee FL

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Widely evaluated regarding the genetic make-up of essential hypertension are the renin-angiotensin-aldosterone system (RAAS) genes polymorphisms, whereas results are often not reproducible. METHOD:We thus focused on a large Fangshan population to explore association of thirteen polymorphisms in five genes o...

journal_title：Journal of hypertension

authors： Niu W,Qi Y,Hou S,Zhai X,Zhou W,Qiu C

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To investigate the characteristics and expression of transforming growth factor (TGF)-beta receptor subtypes on vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. METHODS:The effects of TGF-beta 1 on DNA synthesis were evaluated by [3H]-th...

journal_title：Journal of hypertension

authors： Fukuda N,Kubo A,Izumi Y,Soma M,Kanmatsuse K

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVES:The interactions between eNOS or oxidative stress and bradykinin under long-term treatment of angiotensin II type 1 receptor antagonists (ATRA) remain unknown. To elucidate the molecular mechanisms of the cardioprotective effect of ATRA, we evaluated whether valsartan affects the bradykinin-eNOS and nicotina...

journal_title：Journal of hypertension

authors： Yoshida K,Kobayashi N,Ohno T,Fukushima H,Matsuoka H

更新日期：2007-08-01 00:00:00

abstract：:The European Society of Hypertension and the European Society of Cardiology have started the preparation of the third edition of their joint guidelines on the management of arterial hypertension. The authors have focused on the new edition of the UK NICE guidelines to learn about the difficulties of disentangling evid...

journal_title：Journal of hypertension

authors： Zanchetti A,Mancia G

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:In hypertensive patients, exaggerated increases in vascular resistance and arterial blood pressure have been reported on changing posture from supine to upright. In this study we tested the hypothesis that in hypertensive subjects, upright posture induces an increase in the vasoconstrictor and pressor respons...

journal_title：Journal of hypertension

authors： Legramante JM,Massaro M,Raimondi G,Castrucci F,Cassarino S,Peruzzi G,Iellamo F

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...

journal_title：Journal of hypertension

authors： Stella ML,Mircoli L,Mangoni AA,Giannattasio C,Ferrari AU,Mancia G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Studies were undertaken to clarify the pathophysiologic significance of endogenous endothelin in the control of blood pressure and renal hemodynamics in spontaneously hypertensive rats (SHR). DESIGN:The technique of passive immunization was used to neutralize endogenous endothelin in order to estimate the co...

journal_title：Journal of hypertension

authors： Ohno A,Naruse M,Kato S,Hosaka M,Naruse K,Demura H,Sugino N

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To verify the benefit of renin-angiotensin system blockade in hypertension, the effects of 24 weeks' losartan and ramipril treatment, both alone and in combination, on urinary albumin excretion (UAE) and circulating transforming growth factor beta1 (TGF beta1) have been evaluated in hypertensive subjects with...

journal_title：Journal of hypertension

authors： Scaglione R,Argano C,Corrao S,Di Chiara T,Licata A,Licata G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Blood pressure changes during menopausal transition have not been studied previously using a biracial sample. We investigated whether menopausal transition was associated with change in blood pressure in African-American or white women. DESIGN, SETTING AND PARTICIPANTS:The prospective multicenter study, the ...

journal_title：Journal of hypertension

authors： Luoto R,Sharrett AR,Schreiner P,Sorlie PD,Arnett D,Ephross S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Elevated plasma glucocorticoid level is an independent predictor of increased mortality risk in chronic heart failure, but local biosynthesis and pathophysiological roles of glucocorticoids in the heart remain unclear. METHODS:Dahl salt-sensitive rats on high-salt diet and mice with transthoracic aortic ban...

journal_title：Journal of hypertension

authors： Ohtani T,Mano T,Hikoso S,Sakata Y,Nishio M,Takeda Y,Otsu K,Miwa T,Masuyama T,Hori M,Yamamoto K

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Acute hypertensive response (AHR) in acute stroke is associated with adverse outcomes; however, the underlying pathophysiology of the association is poorly understood and its prognostic impact in ischemic stroke remains unclear. We aimed to investigate the prognostic significance of AHR in patients with isch...

journal_title：Journal of hypertension

authors： Yi JE,Chang Y,Song TJ,Shin GJ,Kim YJ

更新日期：2019-12-01 00:00:00