Eplerenone enhances cardioprotective effects of standard heart failure therapy through matricellular proteins in hypertensive heart failure.

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Data from the Multiple Risk Factor Intervention Trial show an independent direct association between starch intake and blood pressure in American men at higher risk of coronary heart disease. Cross-sectional data from the International Study of Macronutrients and Micronutrients and Blood Pressure (INTERMAP) w...

journal_title：Journal of hypertension

authors： Brown IJ,Elliott P,Robertson CE,Chan Q,Daviglus ML,Dyer AR,Huang CC,Rodriguez BL,Sakata K,Ueshima H,Van Horn L,Zhao L,Stamler J,INTERMAP Research Group.

更新日期：2009-02-01 00:00:00

abstract：:We studied 56 patients with essential hypertension to determine whether responses to standardized laboratory mental and physical challenges accurately reflect blood pressure variability during routine daily activities. Four activities were performed in the laboratory: mental arithmetic, a reaction time test, isometric...

journal_title：Journal of hypertension

authors： Floras JS,Hassan MO,Jones JV,Sleight P

更新日期：1987-12-01 00:00:00

abstract：AIMS:Myocardial fibrosis is a relevant component of hypertensive heart disease (HHD). Novel cardiovascular magnetic resonance (CMR) imaging techniques have shown potential in quantification of diffuse cardiac fibrosis, with T1 mapping, and estimating preclinical cardiac dysfunction, with strain analysis. Molecular biom...

journal_title：Journal of hypertension

authors： Pichler G,Redon J,Martínez F,Solaz E,Calaforra O,Andrés MS,Lopez B,Díez J,Oberbauer R,Adlbrecht C,Karth GD,Maceira A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...

journal_title：Journal of hypertension

authors： van de Borne P,Schintgen M,Niset G,Schoenfeld P,Nguyen H,Degré S,Degaute JP

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinic and ambulatory blood pressure (BP)-lowering efficacy and safety of an aliskiren/amlodipine/hydrochlorothiazide (HCT) triple combination compared with the component dual combinations, in patients with moderate-to-severe hypertension. METHODS:This 8-week, double-blind, randomized, activ...

journal_title：Journal of hypertension

authors： Lacourcière Y,Taddei S,Konis G,Fang H,Severin T,Zhang J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affecte...

journal_title：Journal of hypertension

authors： Lu Y,Sooky L,Silva MJ,Molaodi OR,Karamanos A,Cruickshank JK,Harding S

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To assess the expression of early cardiac genes, implicated in the hypertrophic growth response of the adult heart, in peripheral blood mononuclear cells in patients with essential hypertension and its relationship to ambulatory blood pressure monitoring (ABPM) parameters and to echocardiographic left ventri...

journal_title：Journal of hypertension

authors： Kontaraki JE,Marketou ME,Zacharis EA,Parthenakis FI,Vardas PE

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Molecular variants of the angiotensinogen (AGT) and the angiotensin II type 1 receptor (ATR) genes have been associated with the risk of coronary artery disease (CAD) and myocardial infarction (MI), but data so far available are conflicting. The primary object of the paper is to verify this possible associati...

journal_title：Journal of hypertension

authors： Olivieri O,Stranieri C,Girelli D,Pizzolo F,Grazioli S,Russo C,Pignatti PF,Corrocher R

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...

journal_title：Journal of hypertension

authors： Giubertoni E,Bertelli L,Bartolacelli Y,Origliani G,Modena MG

更新日期：2013-03-01 00:00:00

abstract：:We have previously reported that pressor doses of angiotensin II induce atrial natriuretic factor (ANF) release. Since the number of glomerular and vascular ANF receptors may vary inversely with plasma ANF levels, we investigated whether they are modified by angiotensin II. Male rats were infused intraperitoneally for...

journal_title：Journal of hypertension

authors： Gauquelin G,Schiffrin EL,Garcia R

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify, describe, and evaluate the available cardiovascular disease risk prediction models developed or validated in the hypertensive population. METHODS:MEDLINE and the Web of Science were searched from database inception to March 2019, and all reference lists of included arti...

journal_title：Journal of hypertension

authors： Cai R,Wu X,Li C,Chao J

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To determine the role of current weight in mediating the relationship between birth weight and blood pressure within the context of the 'fetal origins' hypothesis. DESIGN:Prospective cohort study of 2507 pregnant women and their singleton offspring, delivered live at term, in Perth, Western Australia between...

journal_title：Journal of hypertension

authors： Blake KV,Gurrin LC,Evans SF,Beilin LJ,Stanley FJ,Landau LI,Newnham JP

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:We have previously shown that conduit arteries of normotensive (WKY) and hypertensive (SHR) Japanese rats differ from normotensive (LN) and hypertensive (LH) Lyon rats in terms of lower aortic thickness and higher collagen III content, whereas differences in vasoactive properties are unknown. METHODS:Aortic ...

journal_title：Journal of hypertension

authors： Chamiot-Clerc P,Legrand M,Sassard J,Safar ME,Renaud JF

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is established in aged individuals; however, the mechanism(s) are not fully elucidated. We have previously identified l-arginine transport as a potential rate-limiting factor in nitric oxide (NO) production in heart-failure patients, characterized with endothelial dysfunction. We ther...

journal_title：Journal of hypertension

authors： Ahlers BA,Parnell MM,Chin-Dusting JP,Kaye DM

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959-1961) modifies the association between hypertension and CVD. METHODS:We investigated da...

journal_title：Journal of hypertension

authors： Shi Z,Nicholls SJ,Taylor AW,Magliano DJ,Appleton S,Zimmet P

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Hydroxymethylglutaryl coenzyme A (HMGCoA) reductase inhibitors have beneficial effects beyond their cholesterol-lowering properties. The antioxidant mechanism of HMGCoA reductase inhibitors is not completely understood. OBJECTIVES:To elucidate the antioxidant effect of simvastatin. METHODS:We studied the i...

journal_title：Journal of hypertension

authors： Carneado J,Alvarez de Sotomayor M,Perez-Guerrero C,Jimenez L,Herrera MD,Pamies E,Martin-Sanz MD,Stiefel P,Miranda M,Bravo L,Marhuenda E

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Lower parental education is associated with higher adolescent blood pressure (BP). We examined the contribution of modifiable risk factors from infancy to adolescence that could potentially explain the link between parental education and SBP and DBP in the offspring. METHODS:In a prospective Chinese birth c...

journal_title：Journal of hypertension

authors： Kwok MK,Schooling CM,Subramanian SV,Leung GM,Kawachi I

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Cardiac hypertrophy arises as an adaptive response to increased afterload. Studies in knockout mice have shown that catecholamines, but not alpha1-adrenergic receptors, are necessary for such an adaptation to occur. However, whether beta-adrenergic receptors are critical for the development of cardiac hypertr...

journal_title：Journal of hypertension

authors： Palazzesi S,Musumeci M,Catalano L,Patrizio M,Stati T,Michienzi S,Di Certo MG,Mattei E,Vitelli L,Marano G

更新日期：2006-03-01 00:00:00

abstract：:Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...

journal_title：Journal of hypertension

authors： Jamieson MJ,Fowler G,MacDonald TM,Webster J,Witte K,Lawson L,Crichton W,Jeffers TA,Petrie JC

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:To search for a genetic marker of the sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase (SERCA) II gene in spontaneously hypertensive rats (SHRs) and to investigate differences in blood pressure and intracellular Ca2+ among some substrains of SHRs and Wistar-Kyoto (WKY) rats related to their SERCA II genot...

journal_title：Journal of hypertension

authors： Ohno Y,Matsuo K,Suzuki H,Tanase H,Ikeshima H,Takano T,Saruta T

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:Angiotensin (Ang) II increases reactive oxygen species (ROS), decreases nitric oxide (NO) bioavailability and promotes cardiovascular remodeling. ROS have been identified as critical second messengers of the trophic responses by Ang II. In rats with Ang II-induced hypertension, we investigated the role of ROS...

journal_title：Journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:In previous studies we demonstrated that the administration of furosemide associated with L-arginine contributes to enhanced hypotension and induces greater water than electrolyte excretion, in both normal and expansion conditions. The aim of the present study was to elucidate the interaction between furosemi...

journal_title：Journal of hypertension

authors： Costa MA,Loria A,Elesgaray R,Balaszczuk AM,Arranz C

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin ...

journal_title：Journal of hypertension

authors： Thiering E,Brüske I,Kratzsch J,Hoffmann B,Herbarth O,von Berg A,Schaaf B,Wichmann HE,Heinrich J,LISAplus Study Group.

更新日期：2012-06-01 00:00:00

abstract：:The purpose of this study was to examine pressor responsiveness in a rabbit model with adrenal perturbation. Adrenals in rabbits were stabbed with a needle, and the rabbits were given water (adrenal-water group) or 0.9% NaCl (adrenal-salt) to drink; additional rabbits were sham-operated and given water (sham-water gro...

journal_title：Journal of hypertension

authors： Siripaisarnpipat S,Johnson JA,Fowler WL Jr,Zeigler DW,Payne CG

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To seek in hypertensive patients rhythmic variations of the systolic blood pressure signal obtained by ambulatory blood pressure monitoring of any inherent cycle of intermediate value between 1 and 24 h. DESIGN:Subjects (62 hypertensive, 39 normotensive) were evaluated by 24-h ambulatory blood pressure monit...

journal_title：Journal of hypertension

authors： Meisel SR,Mor-Avi V,Rosenthal T,Akselrod S

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Little data is available concerning the prognostic implications of renal function abnormalities, their evolution over time and the effects of nifedipine on such abnormalities in patients with stable angina pectoris. METHODS:The previously published ACTION trial compared long-acting nifedipine GITS 60 mg onc...

journal_title：Journal of hypertension

authors： Ruilope LM,Kirwan BA,de Brouwer S,Danchin N,Fox KA,Wagener G,Segura J,Poole-Wilson PA,Lubsen J,ACTION investigators.

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To characterize an ATP-sensitive K+ channel at the single-channel and tissue level in the vascular smooth muscle of normotensive and genetically hypertensive rats. METHODS:Age- and sex-matched Wistar-Kyoto (WKY) rats and stroke-prone spontaneously hypertensive rats (SHRSP) were used. Patch-clamp single-chann...

journal_title：Journal of hypertension

authors： Furspan PB,Webb RC

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:BPH/2J hypertensive mice have an exaggerated sympathetic contribution to blood pressure (BP). Premotor sympathetic neurons within the rostroventrolateral medulla (RVLM) are a major source of sympathetic vasomotor tone and major site of action of the centrally acting sympatholytic agent, rilmenidine. The relat...

journal_title：Journal of hypertension

authors： Jackson KL,Palma-Rigo K,Nguyen-Huu TP,Davern PJ,Head GA

更新日期：2014-03-01 00:00:00