Impact of genes related to immune tolerance and inflammation (tumour necrosis factor-alpha, interleukin-6) on blood pressure, protein excretion and oedema in pregnancy.

abstract：OBJECTIVE:We have previously reported that hearts from N-[omega]-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats exhibited an enhanced expression of Gi proteins. Since, losartan, an AT1 receptor antagonist, has been shown to attenuate the L-NAME-induced increase in blood pressure, we undertook the pres...

journal_title：Journal of hypertension

authors： Hashim S,Anand-Srivastava MB

更新日期：2004-01-01 00:00:00

abstract：AIMS:Baroreflex activation therapy (BAT) has recently been shown to reduce muscle sympathetic nerve activity and hospitalization rate while improving clinical variables through 6 months of therapy in patients with heart failure and reduced ejection fraction (HFrEF). The objective of the present study is to extend the i...

journal_title：Journal of hypertension

authors： Gronda E,Seravalle G,Trevano FQ,Costantino G,Casini A,Alsheraei A,Lovett EG,Vanoli E,Mancia G,Grassi G

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To study blood pressure and antihypertensive drug treatment in subjects with contrasting family histories of hypertension. SUBJECTS AND METHODS:We grouped 520 offspring examined in 1990 (mean +/- SD age 36 +/- 7 years) according to their parents' blood pressure screened in 1963-1964 as offspring of two normo...

journal_title：Journal of hypertension

authors： Mo R,Omvik P,Lund-Johansen P

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

journal_title：Journal of hypertension

authors： Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the prevalence and distribution of hypertension and to determine the status of hypertension awareness, treatment and control in the Portuguese adult population. METHODS:This study was conducted in 2003, and a multistage cluster sampling method was used to select a...

journal_title：Journal of hypertension

authors： Macedo ME,Lima MJ,Silva AO,Alcantara P,Ramalhinho V,Carmona J

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To compare the anti-hypertensive effect of combination therapy versus a single drug regimen schedule (dose-titration or switching to a different drug class) in type 2 diabetic hypertensive patients with inadequate blood pressure (BP) control on monotherapy. DESIGN:Prospective, randomized, open-fashion, paral...

journal_title：Journal of hypertension

authors： Ruilope LM,de la Sierra A,Moreno E,Fernández R,Garrido J,de la Figuera M,de la Cámara AG,Coca A,Luque-Otero M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To determine the effects of capillary rarefaction on cardiovascular reactivity and microcirculatory functioning in essential hypertension. DESIGN:Hypertension is associated with abnormal cardiovascular reactivity and increased vasoconstriction. Capillary rarefaction amplifies these abnormalities, which modif...

journal_title：Journal of hypertension

authors： Ciuffetti G,Schillaci G,Innocente S,Lombardini R,Pasqualini L,Notaristefano S,Mannarino E

更新日期：2003-12-01 00:00:00

abstract：RATIONALE:Cicletanine (CIC), an anti-hypertensive compound with direct vascular and natriuretic actions, is especially effective in salt-sensitive hypertension, in which dysregulation of the sodium pump plays an important pathogenic role, and digitalis-like cardiotonic steroids contribute to increased vascular tone. Th...

journal_title：Journal of hypertension

authors： Bagrov AY,Dmitrieva RI,Dorofeeva NA,Fedorova OV,Lopatin DA,Lakatta EG,Droy-Lefaix MT

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between birth characteristics and blood pressure at age 20 years and to assess whether effects of birth weight on blood pressure are amplified from childhood to adulthood. DESIGN:A longitudinal study of 584 men and women from Adelaide, Australia, examined previously at 8 years an...

journal_title：Journal of hypertension

authors： Moore VM,Cockington RA,Ryan P,Robinson JS

更新日期：1999-07-01 00:00:00

abstract：INTRODUCTION:Combination therapy is needed to control blood pressure (BP) in a large number of hypertensive patients with diabetes mellitus. Adherence to treatment is a major clinical problem; therefore, the time duration of the antihypertensive action of a drug determines BP control when a dose is skipped. OBJECTIVES...

journal_title：Journal of hypertension

authors： Redon J,Pichler G,Missed Dose Study Group.

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The major advantage of dual inhibitors of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) is their ability to lower blood pressure irrespective of renin or volume status. The aim of this study was to determine whether dual NEP/ACE inhibition produces different effects on cardiovascular str...

journal_title：Journal of hypertension

authors： Farina NK,Johnston CI,Burrell LM

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To estimate the compliance rate and associated factors among a population of hypertensive subjects registered in hospitals and primary health care centres. DESIGN:A prospective study carried out on a sample of hypertensive subjects. METHOD:Compliance with treatment by the study sample was measured using the...

journal_title：Journal of hypertension

authors： Khalil SA,Elzubier AG

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Arterial hypertension is recurrently associated with inflammation of the endothelium as an effect of the upregulation of functional molecules, including cytokines, adhesion molecules and chemokines. However, the role of monocyte chemoattractant protein-1 (MCP-1) in maintaining the inflammatory state of endoth...

journal_title：Journal of hypertension

authors： Tucci M,Quatraro C,Frassanito MA,Silvestris F

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Hemodialysis patients have a cardiovascular mortality rate of 20-40 times that of the general population. Aldosterone inhibition by spironolactone has exerted beneficial, prognostically significant cardiovascular effects in patients with heart failure maintained on hemodialysis or peritoneal dialysis. Our ai...

journal_title：Journal of hypertension

authors： Flevari P,Kalogeropoulou S,Drakou A,Leftheriotis D,Panou F,Lekakis J,Kremastinos D,Vlahakos DV

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine plasma aldosterone concentration (PAC) and plasma renin concentration (PRC) and aldosterone-to-renin ratio (ARR) values in a population attending a Clinic for Cardiovascular Risk Assessment in Children. METHODS:We assessed ARR and associated factors in a cohort of 287 children (137 female, 4-18 ...

journal_title：Journal of hypertension

authors： Genovesi S,Antolini L,Orlando A,Tassistro E,Giussani M,Nava E,Turolo L,Manolopoulou J,Parati G,Morganti A

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To establish whether safety and feasibility of dobutamine and dipyridamole stress echocardiography are affected by history of hypertension. METHODS:Data on 2200 consecutive pharmacologic stress echocardiography (959 dobutamine and 1241 dipyridamole) performed between October 1990 and February 2001 at a sing...

journal_title：Journal of hypertension

authors： Cortigiani L,Zanetti L,Bigi R,Desideri A,Fiorentini C,Nannini E

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:In the BEtter control of BP in hypertensive pAtients monitored Using the HOTMAN sYstem study, we investigated whether utilizing noninvasive monitoring of hemodynamic parameters combined with a drug selection algorithm (integrated hemodynamic management - IHM) compared with conventional drug selection may imp...

journal_title：Journal of hypertension

authors： Fadl Elmula FE,Rebora P,Talvik A,Salerno S,Miszkowska-Nagórna E,Liu X,Heinpalu-Kuum M,Comotti T,Larstorp AC,Rostrup M,Świerblewska E,Valsecchi MG,Kjeldsen SE,Viigimaa M,Narkiewicz K,Parati G,Laurent S,BEtter control of

更新日期：2015-12-01 00:00:00

abstract：:We have studied the effect of parathyroidectomy on the systolic blood pressure, cardiovascular reactivity and the contractile response of isolated aorta to norepinephrine in the genetically hypertensive Lyon rat strain (LH), parathyroidectomized hypertensive Lyon rats (LH-PTX) and parathyroidectomized hypertensive Lyo...

journal_title：Journal of hypertension

authors： Pernot F,Schleiffer R,Vincent M,Sassard J,Gairard A

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Left-ventricular hypertrophy (LVH) is a marker of organ damage in hypertension and helps stratifying cardiovascular risk. Initial left-ventricular mass (LVM) is also a predictor of progression to hypertension, independently of initial blood pressure (BP) and other confounders. OBJECTIVES:To evaluate whether...

journal_title：Journal of hypertension

authors： Izzo R,de Simone G,Devereux RB,Giudice R,De Marco M,Cimmino CS,Vasta A,De Luca N,Trimarco B

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To examine the associations among hypertension, insulin secretion, glucose tolerance and insulin resistance in vivo. DESIGN:Glucose tolerance and insulin secretion during an intravenous glucose tolerance test and action of insulin on whole-body glucose kinetics in the post-absorptive state and during hyperin...

journal_title：Journal of hypertension

authors： Holness MJ,Sugden MC

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:The objective is to evaluate the relationship between cholesterolemia, serum apolipoprotein B (apoB) level and blood pressure in a large sample of general population. METHODS:The Brisighella Heart Study (BHS) is a prospective, population-based longitudinal epidemiological investigation. For this study, we an...

journal_title：Journal of hypertension

authors： Cicero AF,D'Addato S,Veronesi M,Rosticci M,Santi F,Dormi A,Borghi C,Brisighella Heart Study Group.

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Chronic kidney disease (CKD) in which the disease cannot be attributed to any known cause is named CKD of uncertain aetiology (CKDu). The main aims of this analysis were to estimate the prevalence of hypertension and to identify the associated factors in a rural community vulnerable to CKDu and to identify...

journal_title：Journal of hypertension

authors： Senanayake S,Ruwanpathirana T,Gunawardena N

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...

journal_title：Journal of hypertension

authors：

更新日期：1993-03-01 00:00:00

abstract：:Basal platelet function was measured in 35 40-year-old men with untreated mild essential hypertension and compared with 44 age-matched normotensive men. The groups differed significantly with respect to platelet size in venous blood (hypertensive, 7.46 +/- 0.10 X 10(-15) l versus normotensive, 7.11 +/- 0.09 X 10(-15) ...

journal_title：Journal of hypertension

authors： Lande K,Os I,Kjeldsen SE,Westheim A,Hjermann I,Eide I,Gjesdal K

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To examine the interaction of sodium intake with genetic variations of the angiotensinogen gene and hypertension. DESIGN:A community-based case-reference study. SETTING:Two rural Japanese communities. PARTICIPANTS:Non-overweight and non-drinking Japanese men and women: 229 hypertensives and 229 age-, sex- ...

journal_title：Journal of hypertension

authors： Iso H,Harada S,Shimamoto T,Sato S,Kitamura A,Sankai T,Tanigawa T,Iida M,Komachi Y

更新日期：2000-09-01 00:00:00

abstract：:Normotensives with hypertensive parents have been reported to exhibit enhanced cardiovascular reactions to mental stress. We have examined the question of why this result was not confirmed in all studies. In addition we have investigated whether appropriate tests can be performed under clinical rather than laboratory ...

journal_title：Journal of hypertension

authors： Neus H,Gödderz W,Otten H,Rüddel H,von Eiff AW

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To investigate methods to diagnose renal artery stenosis (RAS) among the general hypertensive population. METHODS:We studied the value of clinical and biochemical characteristics at the outpatient clinic to identify subjects with a renal artery narrowing of more than 50% of the luminal surface among 1047 hyp...

journal_title：Journal of hypertension

authors： Bijlstra PJ,Postma CT,de Boo T,Thien T

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Reduction in capillary density or rarefaction is a hallmark of essential hypertension. We measured the retinal capillary density using noninvasive optical coherence tomographic angiography (OCT-A) in adults with treated systemic hypertension and determined possible correlations with ambulatory blood pressure ...

journal_title：Journal of hypertension

authors： Chua J,Chin CWL,Hong J,Chee ML,Le TT,Ting DSW,Wong TY,Schmetterer L

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TI...

journal_title：Journal of hypertension

authors：

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:Scarce data exist on blood pressure (BP) and secondary effects in young athletes. Hence, we aimed to study prevalence of high BP (≥140/90 mmHg) and the association to arterial compliance, left ventricle mass and left atrium volume. METHODS:A Norwegian preparticipation cardiac screening of male professional ...

journal_title：Journal of hypertension

authors： Berge HM,Gjerdalen GF,Andersen TE,Solberg EE,Steine K

更新日期：2013-04-01 00:00:00