Comparative study of the efficacy of olmesartan/amlodipine vs. perindopril/amlodipine in peripheral blood pressure after missed dose in type 2 diabetes.

abstract：:Two formulations of felodipine, conventional and extended release (ER) tablets, were compared in a double-blind, crossover study of patients whose blood pressure was not being controlled using metoprolol 100 mg once daily. Nineteen patients with a supine diastolic blood pressure greater than or equal to 95 mmHg after ...

journal_title：Journal of hypertension

authors： McGrath BP,Langton D,Matthews PG,Syme S,Treloar K,McNeil JJ

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:Nifedipine, an L-type calcium channel blocker, is widely used in the treatment of hypertension and coronary heart diseases, and also exhibits an antiplatelet activity. Activation of peroxisome proliferator-activated receptors (PPARs; α, β/δ, and γ) inhibits the platelet aggregation. Therefore, the purpose of ...

journal_title：Journal of hypertension

authors： Shih CY,Lin MH,Fan HC,Chen FC,Chou TC

更新日期：2014-01-01 00:00:00

abstract：DESIGN:Because of uncertainties regarding the complete antihypertensive mechanism of action of beta-adrenoceptor antagonists, the present study determined whether vagal afferent neurons of humans and rats possess beta-adrenoceptors. Such a location would provide an appropriate target for beta-blockers to modulate neuro...

journal_title：Journal of hypertension

authors： Lawrence AJ,Watkins D,Jarrott B

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The existence and localization of renin in situ was examined in human arteries under non-pathological conditions. DESIGN:Biochemical and immunohistochemical procedures were adopted to examine the existence of renin in human gastroepiploic arteries using an antibody raised against human recombinant renin or a...

journal_title：Journal of hypertension

authors： Okamura T,Aimi Y,Kimura H,Murakami K,Toda N

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:We have previously reported that hearts from N-[omega]-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats exhibited an enhanced expression of Gi proteins. Since, losartan, an AT1 receptor antagonist, has been shown to attenuate the L-NAME-induced increase in blood pressure, we undertook the pres...

journal_title：Journal of hypertension

authors： Hashim S,Anand-Srivastava MB

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:In the nineteenth century, prior to the introduction of the cuff sphygmomanometer, stiffening of arteries was recognized as an indicator of vascular ageing and cardiovascular risk. Through the twentieth century, views on vascular ageing came to focus on brachial blood pressures and on occlusive atherosclerot...

journal_title：Journal of hypertension

authors： Safar ME,Nilsson PM

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:Mechanisms involved in hypertension in homozygous mice for the defective endothelial nitric oxide synthase gene (eNOS-/-) have not been fully elucidated. As NO is a potent vasodilator agent and possibly promotes angiogenesis, we investigated whether vasoconstriction and/or microvascular rarefaction could exp...

journal_title：Journal of hypertension

authors： Kubis N,Richer C,Domergue V,Giudicelli JF,Lévy BI

更新日期：2002-08-01 00:00:00

abstract：AIMS:Myocardial fibrosis is a relevant component of hypertensive heart disease (HHD). Novel cardiovascular magnetic resonance (CMR) imaging techniques have shown potential in quantification of diffuse cardiac fibrosis, with T1 mapping, and estimating preclinical cardiac dysfunction, with strain analysis. Molecular biom...

journal_title：Journal of hypertension

authors： Pichler G,Redon J,Martínez F,Solaz E,Calaforra O,Andrés MS,Lopez B,Díez J,Oberbauer R,Adlbrecht C,Karth GD,Maceira A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To examine the associations among hypertension, insulin secretion, glucose tolerance and insulin resistance in vivo. DESIGN:Glucose tolerance and insulin secretion during an intravenous glucose tolerance test and action of insulin on whole-body glucose kinetics in the post-absorptive state and during hyperin...

journal_title：Journal of hypertension

authors： Holness MJ,Sugden MC

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The use of thiazide diuretics in the treatment of hypertension is widely considered as a first-line treatment, given the efficacy and low cost of this class of drugs. This indication is not unanimous, because thiazides can cause metabolic alterations, and other side effects that reduce compliance and persist...

journal_title：Journal of hypertension

authors： Trimarco V,de Simone G,Izzo R,De Luca N,Giudice R,Marino M,Damiano S,Rozza F,Trimarco B,Di Renzo G

更新日期：2012-06-01 00:00:00

abstract：:Medical records were examined for 1935 patients who presented sequentially to a hypertension clinic between 1971 and 1981. Patients were classified according to whether they were on a beta-blocker, methyldopa, a potassium-losing diuretic, or whether they had discontinued any of these treatments. Age-standardized morta...

journal_title：Journal of hypertension

authors： Franks PJ,Hartley K,Bulpitt PF,Bulpitt CJ,Dollery CT

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of angiotensins acting at the rostral ventrolateral medulla (RVLM) on the cardiovascular adjustments following haemorrhage. DESIGN:Changes in mean arterial pressure (MAP) and heart rate (HR) produced by micro-injections of angiotensin II (Ang II) and angiotensin (Ang)-(1-7) and differ...

journal_title：Journal of hypertension

authors： Lima DX,Campagnole-Santos MJ,Fontes MA,Khosla MC,Santos RA

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:Local atrial tissue angiotensin II (AngII) level is elevated in atrial fibrillation (AF), but the mechanism is unknown. We hypothesized that atrial myocytes express all components of the renin-angiotensin system (RAS) and investigated whether rapid depolarization alone is sufficient to increase paracrine Ang...

journal_title：Journal of hypertension

authors： Tsai CT,Lai LP,Hwang JJ,Chen WP,Chiang FT,Hsu KL,Tseng CD,Tseng YZ,Lin JL

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Angiotensin II causes hypertension not only by direct constriction of vascular smooth muscle, but also by facilitating the release of noradrenaline from sympathetic terminals and by enhancing vascular noradrenaline sensitivity. AT1 receptor antagonists attenuate all these actions, but display some evidence o...

journal_title：Journal of hypertension

authors： Dendorfer A,Dominiak P,Tempel K,Raasch W

更新日期：2005-10-01 00:00:00

abstract：:: We aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and ...

journal_title：Journal of hypertension

authors： Pinho-Gomes AC,Azevedo L,Bidel Z,Nazarzadeh M,Canoy D,Copland E,Salam A,Rodgers A,Kotecha D,Rahimi K

更新日期：2019-09-01 00:00:00

abstract：:Hypertension is associated with thickening of the wall of resistance vessels, but the cellular or genetic basis of this is unclear. Cell proliferation and intracellular alkalinization via increased Na+/H+ exchange are linked in the response of tissues to growth factors. To define a possible cellular basis for vascular...

journal_title：Journal of hypertension

authors： Ng LL,Dudley C,Bomford J,Hawley D

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolo...

journal_title：Journal of hypertension

authors： Brooksby P,Levi AJ,Jones JV

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypert...

journal_title：Journal of hypertension

authors： Koton S,Tanne D,Grossman E

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To investigate the association between long-term exposure to high-level urban traffic noise and blood pressure in preschool children. DESIGN:Normotensive children (n = 1542), aged 3-7 years and attending kindergartens, had their blood pressures and heart rate measured. Mean values of these circulatory variab...

journal_title：Journal of hypertension

authors： Regecová V,Kellerová E

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:This study was designed to compare the effects of prostaglandin synthesis inhibition on calculated preglomerular and postglomerular resistance in hypertensive patients with unilateral renal artery stenosis (RAS) and in patients with essential hypertension. DESIGN AND METHODS:Sixteen patients with suspected r...

journal_title：Journal of hypertension

authors： Milot A,Lambert R,Lebel M,Cusson JR,Larochelle P

更新日期：1996-06-01 00:00:00

abstract：:Fenoldopam, a dopamine-1 (D1) agonist, was administered by a 6-h intravenous infusion to patients with refractory hypertension [diastolic blood pressure (DBP) greater than 115 mmHg while on triple therapy] in order to achieve a fall in DBP of 30 mmHg. The evolution of blood pressure, heart rate, glomerular filtration ...

journal_title：Journal of hypertension

authors： Ruilope LM,Robles RG,Miranda B,Tovar J,Alcazar JM,Sancho J,Rodicio JL,Martinez A,Astorga A,Beck T

更新日期：1988-08-01 00:00:00

abstract：:: The aim of the current article is to review the current evidence on the role of morning blood pressure (BP) in the management of hypertension. Morning BP surge had been and will continue to be a hot topic of hypertension research. However, more evidence is needed to prove its clinical usefulness in the management of...

journal_title：Journal of hypertension

authors： Wang JG,Kario K,Park JB,Chen CH

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:There are no studies that relate BsmI polymorphism of the vitamin D receptor (VDR) gene and with vitamin D to blood pressure (BP). OBJECTIVE:To analyze if this polymorphism and 25-hydroxyvitamin D levels (25OHD3) influence BP in a population of healthy subjects. DESIGN:Transversal study on healthy populati...

journal_title：Journal of hypertension

authors： Muray S,Parisi E,Cardús A,Craver L,Fernández E

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:To examine the health risks associated with smoking and blood pressure in Chinese hypertensive patients and to compare the benefit of antihypertensive drug treatment with the risk attributable to smoking. METHODS:We used multiple Cox regression to correlate outcome with blood pressure and smoking status in ...

journal_title：Journal of hypertension

authors： Wang JG,Staessen JA,Fagard R,Gong L,Liu L,Systolic Hypertension in China (Syst-China) Trial Collaborative Group.

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) recovery after orthostatic hypotension might be important to prevent cerebral hypoperfusion episodes in older adults, and be related to better clinical outcome. The objective was to study the relationship between BP recovery and clinical outcome, that is physical and cognitive performance,...

journal_title：Journal of hypertension

authors： Mol A,Slangen LRN,van Wezel RJA,Maier AB,Meskers CGM

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To introduce a new method, the smoothness index, for assessing the homogeneity of 24 h blood pressure reduction by antihypertensive treatment and to compare it with the trough : peak ratio; and to assess the ability of both indices to predict a reduction in the left ventricular mass index induced by treatment...

journal_title：Journal of hypertension

authors： Parati G,Omboni S,Rizzoni D,Agabiti-Rosei E,Mancia G

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:Globally, healthcare policy promotes supported self-management as a strategy for people with long-term conditions. This meta-review aimed to explore how people with hypertension make sense of their condition, to assess the effectiveness of supported self-management in hypertension, and to identify effective ...

journal_title：Journal of hypertension

authors： Shahaj O,Denneny D,Schwappach A,Pearce G,Epiphaniou E,Parke HL,Taylor SJC,Pinnock H

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Bradykinin is a potent cardioprotective hormone, the beneficial role of which in vivo appears to be limited by its rapid metabolism. Inhibitors of peptidases that degrade endogenously formed bradykinin are themselves cardioprotective, presumably by increasing local bradykinin concentrations. As bradykinin-de...

journal_title：Journal of hypertension

authors： Taylor-McCabe KJ,Erşahin C,Simmons WH

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:Acute hypertensive response (AHR) in acute stroke is associated with adverse outcomes; however, the underlying pathophysiology of the association is poorly understood and its prognostic impact in ischemic stroke remains unclear. We aimed to investigate the prognostic significance of AHR in patients with isch...

journal_title：Journal of hypertension

authors： Yi JE,Chang Y,Song TJ,Shin GJ,Kim YJ

更新日期：2019-12-01 00:00:00

abstract：AIM:Studies addressing the association between a reduced drop of heart rate (HR) at night with subclinical organ damage and cardiovascular events in the general population are scanty. We evaluated this issue in individuals enrolled in the Pressioni Monitorate E Loro Associazioni study. METHODS:At entry, 2021 individua...

journal_title：Journal of hypertension

authors： Cuspidi C,Facchetti R,Bombelli M,Sala C,Tadic M,Grassi G,Mancia G

更新日期：2018-06-01 00:00:00